Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W288369321', 'doi': 'https://doi.org/10.1023/a:1006596620406', 'title': 'Overexpression of tissue inhibitor of matrix metalloproteinases-1 (TIMP-1) in metastatic MDCK cells transformed by v-src.', 'display_name': 'Overexpression of tissue inhibitor of matrix metalloproteinases-1 (TIMP-1) in metastatic MDCK cells transformed by v-src.', 'publication_year': 1999, 'publication_date': '1999-01-01', 'ids': {'openalex': 'https://openalex.org/W288369321', 'doi': 'https://doi.org/10.1023/a:1006596620406', 'mag': '288369321', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/10411101'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1023/a:1006596620406', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S100674681', 'display_name': 'Clinical & Experimental Metastasis', 'issn_l': '0262-0898', 'issn': ['0262-0898', '1573-7276'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310319900', 'host_organization_name': 'Springer Science+Business Media', 'host_organization_lineage': ['https://openalex.org/P4310319965', 'https://openalex.org/P4310319900'], 'host_organization_lineage_names': ['Springer Nature', 'Springer Science+Business Media'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5004574558', 'display_name': 'Hanae Noritake', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I10091056', 'display_name': 'Kanazawa University', 'ror': 'https://ror.org/02hwp6a56', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I10091056']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Hanae Noritake', 'raw_affiliation_strings': ['Department of Molecular Virology and Oncology, Cancer Research Institute, Kanazawa University, Japan.'], 'affiliations': [{'raw_affiliation_string': 'Department of Molecular Virology and Oncology, Cancer Research Institute, Kanazawa University, Japan.', 'institution_ids': ['https://openalex.org/I10091056']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5082942100', 'display_name': 'Hisashi Miyamori', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I10091056', 'display_name': 'Kanazawa University', 'ror': 'https://ror.org/02hwp6a56', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I10091056']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Hisashi Miyamori', 'raw_affiliation_strings': ['Department of Molecular Virology and Oncology , Cancer Research Institute, Kanazawa University , Kanazawa, Japan'], 'affiliations': [{'raw_affiliation_string': 'Department of Molecular Virology and Oncology , Cancer Research Institute, Kanazawa University , Kanazawa, Japan', 'institution_ids': ['https://openalex.org/I10091056']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5024944859', 'display_name': 'Chisa Goto', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I10091056', 'display_name': 'Kanazawa University', 'ror': 'https://ror.org/02hwp6a56', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I10091056']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Chisa Goto', 'raw_affiliation_strings': ['Department of Molecular Virology and Oncology , Cancer Research Institute, Kanazawa University , Kanazawa, Japan'], 'affiliations': [{'raw_affiliation_string': 'Department of Molecular Virology and Oncology , Cancer Research Institute, Kanazawa University , Kanazawa, Japan', 'institution_ids': ['https://openalex.org/I10091056']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5008902984', 'display_name': 'Motoharu Seiki', 'orcid': 'https://orcid.org/0000-0002-3909-0782'}, 'institutions': [{'id': 'https://openalex.org/I74801974', 'display_name': 'The University of Tokyo', 'ror': 'https://ror.org/057zh3y96', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I74801974']}, {'id': 'https://openalex.org/I161296585', 'display_name': 'Tokyo University of Science', 'ror': 'https://ror.org/05sj3n476', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I161296585']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Motoharu Seiki', 'raw_affiliation_strings': ['Department of Cancer Cells, Institute of Medical Science, University of Tokyo, Tokyo, Japan'], 'affiliations': [{'raw_affiliation_string': 'Department of Cancer Cells, Institute of Medical Science, University of Tokyo, Tokyo, Japan', 'institution_ids': ['https://openalex.org/I74801974', 'https://openalex.org/I161296585']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5007332542', 'display_name': 'Hiroshi Satô', 'orcid': 'https://orcid.org/0000-0002-0030-8078'}, 'institutions': [{'id': 'https://openalex.org/I10091056', 'display_name': 'Kanazawa University', 'ror': 'https://ror.org/02hwp6a56', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I10091056']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Hiroshi Sato', 'raw_affiliation_strings': ['Department of Molecular Virology and Oncology , Cancer Research Institute, Kanazawa University , Kanazawa, Japan'], 'affiliations': [{'raw_affiliation_string': 'Department of Molecular Virology and Oncology , Cancer Research Institute, Kanazawa University , Kanazawa, Japan', 'institution_ids': ['https://openalex.org/I10091056']}]}], 'countries_distinct_count': 1, 'institutions_distinct_count': 3, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': {'value': 3290, 'currency': 'EUR', 'value_usd': 4290, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 0.666, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 25, 'citation_normalized_percentile': {'value': 0.660639, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 86, 'max': 87}, 'biblio': {'volume': '17', 'issue': '2', 'first_page': '105', 'last_page': '110'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10620', 'display_name': 'Role of Matrix Metalloproteinases in Cancer and Physiology', 'score': 0.9998, 'subfield': {'id': 'https://openalex.org/subfields/1306', 'display_name': 'Cancer Research'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10620', 'display_name': 'Role of Matrix Metalloproteinases in Cancer and Physiology', 'score': 0.9998, 'subfield': {'id': 'https://openalex.org/subfields/1306', 'display_name': 'Cancer Research'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T12505', 'display_name': 'Role of Fibroblast Activation in Cancer Progression', 'score': 0.9992, 'subfield': {'id': 'https://openalex.org/subfields/2730', 'display_name': 'Oncology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T12110', 'display_name': 'Role of Osteopontin in Biomineralization and Inflammation', 'score': 0.9971, 'subfield': {'id': 'https://openalex.org/subfields/2745', 'display_name': 'Rheumatology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/matrix-metalloproteinases', 'display_name': 'Matrix Metalloproteinases', 'score': 0.540602}, {'id': 'https://openalex.org/keywords/clone', 'display_name': 'clone (Java method)', 'score': 0.44143808}], 'concepts': [{'id': 'https://openalex.org/C109523444', 'wikidata': 'https://www.wikidata.org/wiki/Q424216', 'display_name': 'Matrix metalloproteinase', 'level': 2, 'score': 0.7492186}, {'id': 'https://openalex.org/C54009773', 'wikidata': 'https://www.wikidata.org/wiki/Q1429031', 'display_name': 'Transfection', 'level': 3, 'score': 0.67668355}, {'id': 'https://openalex.org/C108636557', 'wikidata': 'https://www.wikidata.org/wiki/Q21109354', 'display_name': 'Proto-oncogene tyrosine-protein kinase Src', 'level': 3, 'score': 0.517533}, {'id': 'https://openalex.org/C96232424', 'wikidata': 'https://www.wikidata.org/wiki/Q4118072', 'display_name': 'Cancer cell', 'level': 3, 'score': 0.48541865}, {'id': 'https://openalex.org/C153911025', 'wikidata': 'https://www.wikidata.org/wiki/Q7202', 'display_name': 'Molecular biology', 'level': 1, 'score': 0.4854084}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.47408783}, {'id': 'https://openalex.org/C81089528', 'wikidata': 'https://www.wikidata.org/wiki/Q5134986', 'display_name': 'clone (Java method)', 'level': 3, 'score': 0.44143808}, {'id': 'https://openalex.org/C189165786', 'wikidata': 'https://www.wikidata.org/wiki/Q193825', 'display_name': 'Extracellular matrix', 'level': 2, 'score': 0.4318556}, {'id': 'https://openalex.org/C55728118', 'wikidata': 'https://www.wikidata.org/wiki/Q425402', 'display_name': 'Metalloproteinase', 'level': 3, 'score': 0.41922322}, {'id': 'https://openalex.org/C81885089', 'wikidata': 'https://www.wikidata.org/wiki/Q189082', 'display_name': 'Cell culture', 'level': 2, 'score': 0.4164193}, {'id': 'https://openalex.org/C2779013556', 'wikidata': 'https://www.wikidata.org/wiki/Q181876', 'display_name': 'Metastasis', 'level': 3, 'score': 0.4109407}, {'id': 'https://openalex.org/C95444343', 'wikidata': 'https://www.wikidata.org/wiki/Q7141', 'display_name': 'Cell biology', 'level': 1, 'score': 0.39786804}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.37991118}, {'id': 'https://openalex.org/C502942594', 'wikidata': 'https://www.wikidata.org/wiki/Q3421914', 'display_name': 'Cancer research', 'level': 1, 'score': 0.34938556}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.29942977}, {'id': 'https://openalex.org/C121608353', 'wikidata': 'https://www.wikidata.org/wiki/Q12078', 'display_name': 'Cancer', 'level': 2, 'score': 0.22640643}, {'id': 'https://openalex.org/C62478195', 'wikidata': 'https://www.wikidata.org/wiki/Q828130', 'display_name': 'Signal transduction', 'level': 2, 'score': 0.15200138}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.09887552}, {'id': 'https://openalex.org/C54355233', 'wikidata': 'https://www.wikidata.org/wiki/Q7162', 'display_name': 'Genetics', 'level': 1, 'score': 0.07291603}], 'mesh': [{'descriptor_ui': 'D017364', 'descriptor_name': 'Collagenases', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': True}, {'descriptor_ui': 'D004847', 'descriptor_name': 'Epithelial Cells', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D016391', 'descriptor_name': 'Genes, src', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': True}, {'descriptor_ui': 'D007680', 'descriptor_name': 'Kidney Neoplasms', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D019715', 'descriptor_name': 'Tissue Inhibitor of Metalloproteinase-1', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': True}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001483', 'descriptor_name': 'Base Sequence', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015153', 'descriptor_name': 'Blotting, Western', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002461', 'descriptor_name': 'Cell Line, Transformed', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D003001', 'descriptor_name': 'Cloning, Molecular', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D017364', 'descriptor_name': 'Collagenases', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D018076', 'descriptor_name': 'DNA, Complementary', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D018076', 'descriptor_name': 'DNA, Complementary', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D004285', 'descriptor_name': 'Dogs', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004847', 'descriptor_name': 'Epithelial Cells', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005780', 'descriptor_name': 'Gelatin', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005780', 'descriptor_name': 'Gelatin', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D016391', 'descriptor_name': 'Genes, src', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007668', 'descriptor_name': 'Kidney', 'qualifier_ui': 'Q000166', 'qualifier_name': 'cytology', 'is_major_topic': False}, {'descriptor_ui': 'D007668', 'descriptor_name': 'Kidney', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007680', 'descriptor_name': 'Kidney Neoplasms', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D020781', 'descriptor_name': 'Matrix Metalloproteinase 1', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D061965', 'descriptor_name': 'Matrix Metalloproteinase Inhibitors', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D051379', 'descriptor_name': 'Mice', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008819', 'descriptor_name': 'Mice, Nude', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008969', 'descriptor_name': 'Molecular Sequence Data', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009362', 'descriptor_name': 'Neoplasm Metastasis', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D019715', 'descriptor_name': 'Tissue Inhibitor of Metalloproteinase-1', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D019715', 'descriptor_name': 'Tissue Inhibitor of Metalloproteinase-1', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D014407', 'descriptor_name': 'Tumor Cells, Cultured', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015854', 'descriptor_name': 'Up-Regulation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1023/a:1006596620406', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S100674681', 'display_name': 'Clinical & Experimental Metastasis', 'issn_l': '0262-0898', 'issn': ['0262-0898', '1573-7276'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310319900', 'host_organization_name': 'Springer Science+Business Media', 'host_organization_lineage': ['https://openalex.org/P4310319965', 'https://openalex.org/P4310319900'], 'host_organization_lineage_names': ['Springer Nature', 'Springer Science+Business Media'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/10411101', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 33, 'referenced_works': ['https://openalex.org/W1490966335', 'https://openalex.org/W1559851036', 'https://openalex.org/W1573411722', 'https://openalex.org/W1581095210', 'https://openalex.org/W1583835478', 'https://openalex.org/W1604342691', 'https://openalex.org/W1648100608', 'https://openalex.org/W178142526', 'https://openalex.org/W1799809595', 'https://openalex.org/W1949259756', 'https://openalex.org/W1974492547', 'https://openalex.org/W1978680709', 'https://openalex.org/W1979390430', 'https://openalex.org/W1983219998', 'https://openalex.org/W1996543534', 'https://openalex.org/W2000903132', 'https://openalex.org/W2012348648', 'https://openalex.org/W2015849738', 'https://openalex.org/W2026151657', 'https://openalex.org/W2043068076', 'https://openalex.org/W2043250294', 'https://openalex.org/W2048441028', 'https://openalex.org/W2052047439', 'https://openalex.org/W2052626837', 'https://openalex.org/W2072447465', 'https://openalex.org/W2088479573', 'https://openalex.org/W2119050264', 'https://openalex.org/W2130627807', 'https://openalex.org/W2132012838', 'https://openalex.org/W2160834627', 'https://openalex.org/W2165190607', 'https://openalex.org/W2444390998', 'https://openalex.org/W4229764094'], 'related_works': ['https://openalex.org/W985133341', 'https://openalex.org/W2402700372', 'https://openalex.org/W2392720592', 'https://openalex.org/W2382282969', 'https://openalex.org/W2359992629', 'https://openalex.org/W2342111204', 'https://openalex.org/W2147894248', 'https://openalex.org/W2052144929', 'https://openalex.org/W2002035242', 'https://openalex.org/W1648100608'], 'abstract_inverted_index': None, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W288369321', 'counts_by_year': [{'year': 2019, 'cited_by_count': 1}, {'year': 2016, 'cited_by_count': 1}, {'year': 2014, 'cited_by_count': 1}], 'updated_date': '2024-08-15T15:14:57.206604', 'created_date': '2016-06-24'}