Publication Information

{'id': 'https://openalex.org/W2845494217', 'doi': 'https://doi.org/10.3960/jslrt.18001', 'title': 'The expression of PD-1 ligands and IDO1 by macrophage/microglia in primary central nervous system lymphoma', 'display_name': 'The expression of PD-1 ligands and IDO1 by macrophage/microglia in primary central nervous system lymphoma', 'publication_year': 2018, 'publication_date': '2018-01-01', 'ids': {'openalex': 'https://openalex.org/W2845494217', 'doi': 'https://doi.org/10.3960/jslrt.18001', 'mag': '2845494217', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/29998979', 'pmcid': 'https://www.ncbi.nlm.nih.gov/pmc/articles/6413151'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.3960/jslrt.18001', 'pdf_url': 'https://www.jstage.jst.go.jp/article/jslrt/58/2/58_18001/_pdf', 'source': {'id': 'https://openalex.org/S94741007', 'display_name': 'Journal of Clinical and Experimental Hematopathology', 'issn_l': '1346-4280', 'issn': ['1346-4280', '1880-9952'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': None, 'host_organization_name': None, 'host_organization_lineage': [], 'host_organization_lineage_names': [], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'gold', 'oa_url': 'https://www.jstage.jst.go.jp/article/jslrt/58/2/58_18001/_pdf', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5108914579', 'display_name': 'Yuko Miyasato', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I96036126', 'display_name': 'Kumamoto University', 'ror': 'https://ror.org/02cgss904', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I96036126']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Yuko Miyasato', 'raw_affiliation_strings': [') Department of Cell Pathology, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan,'], 'affiliations': [{'raw_affiliation_string': ') Department of Cell Pathology, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan,', 'institution_ids': ['https://openalex.org/I96036126']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5054154659', 'display_name': 'Yasuo Takashima', 'orcid': 'https://orcid.org/0000-0001-8876-6673'}, 'institutions': [{'id': 'https://openalex.org/I40677808', 'display_name': 'Kyoto Prefectural University of Medicine', 'ror': 'https://ror.org/028vxwa22', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I40677808']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Yasuo Takashima', 'raw_affiliation_strings': [') Kyoto Prefectural University of Medicine, Graduate School for Health Care Science, Kyoto, Japan,'], 'affiliations': [{'raw_affiliation_string': ') Kyoto Prefectural University of Medicine, Graduate School for Health Care Science, Kyoto, Japan,', 'institution_ids': ['https://openalex.org/I40677808']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5069676632', 'display_name': 'Hiroto Takeya', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I96036126', 'display_name': 'Kumamoto University', 'ror': 'https://ror.org/02cgss904', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I96036126']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Hiroto Takeya', 'raw_affiliation_strings': [') Department of Cell Pathology, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan,'], 'affiliations': [{'raw_affiliation_string': ') Department of Cell Pathology, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan,', 'institution_ids': ['https://openalex.org/I96036126']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5031494774', 'display_name': 'Hiromu Yano', 'orcid': 'https://orcid.org/0000-0003-3985-0259'}, 'institutions': [{'id': 'https://openalex.org/I96036126', 'display_name': 'Kumamoto University', 'ror': 'https://ror.org/02cgss904', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I96036126']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Hiromu Yano', 'raw_affiliation_strings': [') Department of Cell Pathology, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan,'], 'affiliations': [{'raw_affiliation_string': ') Department of Cell Pathology, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan,', 'institution_ids': ['https://openalex.org/I96036126']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5067761683', 'display_name': 'Azusa Hayano', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I40677808', 'display_name': 'Kyoto Prefectural University of Medicine', 'ror': 'https://ror.org/028vxwa22', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I40677808']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Azusa Hayano', 'raw_affiliation_strings': [') Kyoto Prefectural University of Medicine, Graduate School for Health Care Science, Kyoto, Japan,'], 'affiliations': [{'raw_affiliation_string': ') Kyoto Prefectural University of Medicine, Graduate School for Health Care Science, Kyoto, Japan,', 'institution_ids': ['https://openalex.org/I40677808']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5109983338', 'display_name': 'Takenobu Nakagawa', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I96036126', 'display_name': 'Kumamoto University', 'ror': 'https://ror.org/02cgss904', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I96036126']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Takenobu Nakagawa', 'raw_affiliation_strings': [') Department of Cell Pathology, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan,'], 'affiliations': [{'raw_affiliation_string': ') Department of Cell Pathology, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan,', 'institution_ids': ['https://openalex.org/I96036126']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5027494058', 'display_name': 'Keishi Makino', 'orcid': 'https://orcid.org/0000-0002-4607-2646'}, 'institutions': [{'id': 'https://openalex.org/I96036126', 'display_name': 'Kumamoto University', 'ror': 'https://ror.org/02cgss904', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I96036126']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Keishi Makino', 'raw_affiliation_strings': [') Department of Neurosurgery, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan.'], 'affiliations': [{'raw_affiliation_string': ') Department of Neurosurgery, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan.', 'institution_ids': ['https://openalex.org/I96036126']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5026409331', 'display_name': 'Motohiro Takeya', 'orcid': 'https://orcid.org/0000-0003-3694-1294'}, 'institutions': [{'id': 'https://openalex.org/I96036126', 'display_name': 'Kumamoto University', 'ror': 'https://ror.org/02cgss904', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I96036126']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Motohiro Takeya', 'raw_affiliation_strings': [') Department of Cell Pathology, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan,'], 'affiliations': [{'raw_affiliation_string': ') Department of Cell Pathology, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan,', 'institution_ids': ['https://openalex.org/I96036126']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5030817537', 'display_name': 'Ryuya Yamanaka', 'orcid': 'https://orcid.org/0000-0003-2941-7996'}, 'institutions': [{'id': 'https://openalex.org/I40677808', 'display_name': 'Kyoto Prefectural University of Medicine', 'ror': 'https://ror.org/028vxwa22', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I40677808']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Ryuya Yamanaka', 'raw_affiliation_strings': [') Kyoto Prefectural University of Medicine, Graduate School for Health Care Science, Kyoto, Japan,'], 'affiliations': [{'raw_affiliation_string': ') Kyoto Prefectural University of Medicine, Graduate School for Health Care Science, Kyoto, Japan,', 'institution_ids': ['https://openalex.org/I40677808']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5072733384', 'display_name': 'Yoshihiro Komohara', 'orcid': 'https://orcid.org/0000-0001-9723-0846'}, 'institutions': [{'id': 'https://openalex.org/I96036126', 'display_name': 'Kumamoto University', 'ror': 'https://ror.org/02cgss904', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I96036126']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Yoshihiro Komohara', 'raw_affiliation_strings': [') Department of Cell Pathology, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan,'], 'affiliations': [{'raw_affiliation_string': ') Department of Cell Pathology, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan,', 'institution_ids': ['https://openalex.org/I96036126']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 2, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': {'value': 120000, 'currency': 'JPY', 'value_usd': 1200, 'provenance': 'doaj'}, 'apc_paid': {'value': 120000, 'currency': 'JPY', 'value_usd': 1200, 'provenance': 'doaj'}, 'fwci': 3.034, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 45, 'citation_normalized_percentile': {'value': 0.832421, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 96, 'max': 97}, 'biblio': {'volume': '58', 'issue': '2', 'first_page': '95', 'last_page': '101'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T11266', 'display_name': 'Neuroinflammation and Neurodegeneration Mechanisms', 'score': 0.9995, 'subfield': {'id': 'https://openalex.org/subfields/2808', 'display_name': 'Neurology'}, 'field': {'id': 'https://openalex.org/fields/28', 'display_name': 'Neuroscience'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T11266', 'display_name': 'Neuroinflammation and Neurodegeneration Mechanisms', 'score': 0.9995, 'subfield': {'id': 'https://openalex.org/subfields/2808', 'display_name': 'Neurology'}, 'field': {'id': 'https://openalex.org/fields/28', 'display_name': 'Neuroscience'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T12212', 'display_name': 'CNS Lymphoma Diagnosis and Treatment', 'score': 0.9994, 'subfield': {'id': 'https://openalex.org/subfields/2728', 'display_name': 'Neurology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T11337', 'display_name': 'Tryptophan and brain disorders', 'score': 0.9956, 'subfield': {'id': 'https://openalex.org/subfields/2803', 'display_name': 'Biological Psychiatry'}, 'field': {'id': 'https://openalex.org/fields/28', 'display_name': 'Neuroscience'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/tumor-associated-macrophage', 'display_name': 'Tumor-associated macrophage', 'score': 0.49790335}, {'id': 'https://openalex.org/keywords/cd163', 'display_name': 'CD163', 'score': 0.49292874}, {'id': 'https://openalex.org/keywords/monocyte', 'display_name': 'Monocyte', 'score': 0.42421234}], 'concepts': [{'id': 'https://openalex.org/C2781173314', 'wikidata': 'https://www.wikidata.org/wiki/Q3246818', 'display_name': 'Primary central nervous system lymphoma', 'level': 3, 'score': 0.86021554}, {'id': 'https://openalex.org/C2779830541', 'wikidata': 'https://www.wikidata.org/wiki/Q1622829', 'display_name': 'Microglia', 'level': 3, 'score': 0.7003933}, {'id': 'https://openalex.org/C502942594', 'wikidata': 'https://www.wikidata.org/wiki/Q3421914', 'display_name': 'Cancer research', 'level': 1, 'score': 0.6342485}, {'id': 'https://openalex.org/C171958077', 'wikidata': 'https://www.wikidata.org/wiki/Q419333', 'display_name': 'STAT protein', 'level': 4, 'score': 0.62162256}, {'id': 'https://openalex.org/C2779244956', 'wikidata': 'https://www.wikidata.org/wiki/Q184204', 'display_name': 'Macrophage', 'level': 3, 'score': 0.5158593}, {'id': 'https://openalex.org/C2779482015', 'wikidata': 'https://www.wikidata.org/wiki/Q17121648', 'display_name': 'Tumor-associated macrophage', 'level': 4, 'score': 0.49790335}, {'id': 'https://openalex.org/C8891405', 'wikidata': 'https://www.wikidata.org/wiki/Q1059', 'display_name': 'Immune system', 'level': 2, 'score': 0.49324387}, {'id': 'https://openalex.org/C2775858924', 'wikidata': 'https://www.wikidata.org/wiki/Q18034009', 'display_name': 'CD163', 'level': 4, 'score': 0.49292874}, {'id': 'https://openalex.org/C2776107976', 'wikidata': 'https://www.wikidata.org/wiki/Q1786433', 'display_name': 'Tumor microenvironment', 'level': 3, 'score': 0.48076817}, {'id': 'https://openalex.org/C2777701055', 'wikidata': 'https://www.wikidata.org/wiki/Q1427096', 'display_name': 'Immunotherapy', 'level': 3, 'score': 0.46798965}, {'id': 'https://openalex.org/C81885089', 'wikidata': 'https://www.wikidata.org/wiki/Q189082', 'display_name': 'Cell culture', 'level': 2, 'score': 0.44988683}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.43789697}, {'id': 'https://openalex.org/C2779338263', 'wikidata': 'https://www.wikidata.org/wiki/Q208414', 'display_name': 'Lymphoma', 'level': 2, 'score': 0.43674543}, {'id': 'https://openalex.org/C2781184567', 'wikidata': 'https://www.wikidata.org/wiki/Q107244', 'display_name': 'Monocyte', 'level': 2, 'score': 0.42421234}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.3595789}, {'id': 'https://openalex.org/C203014093', 'wikidata': 'https://www.wikidata.org/wiki/Q101929', 'display_name': 'Immunology', 'level': 1, 'score': 0.35660574}, {'id': 'https://openalex.org/C95444343', 'wikidata': 'https://www.wikidata.org/wiki/Q7141', 'display_name': 'Cell biology', 'level': 1, 'score': 0.32917625}, {'id': 'https://openalex.org/C62478195', 'wikidata': 'https://www.wikidata.org/wiki/Q828130', 'display_name': 'Signal transduction', 'level': 2, 'score': 0.23174766}, {'id': 'https://openalex.org/C2776914184', 'wikidata': 'https://www.wikidata.org/wiki/Q101991', 'display_name': 'Inflammation', 'level': 2, 'score': 0.14663222}, {'id': 'https://openalex.org/C202751555', 'wikidata': 'https://www.wikidata.org/wiki/Q221681', 'display_name': 'In vitro', 'level': 2, 'score': 0.09636593}, {'id': 'https://openalex.org/C2778923194', 'wikidata': 'https://www.wikidata.org/wiki/Q14912019', 'display_name': 'STAT3', 'level': 3, 'score': 0.09201449}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.0}, {'id': 'https://openalex.org/C54355233', 'wikidata': 'https://www.wikidata.org/wiki/Q7162', 'display_name': 'Genetics', 'level': 1, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D060890', 'descriptor_name': 'B7-H1 Antigen', 'qualifier_ui': 'Q000276', 'qualifier_name': 'immunology', 'is_major_topic': True}, {'descriptor_ui': 'D016543', 'descriptor_name': 'Central Nervous System Neoplasms', 'qualifier_ui': 'Q000276', 'qualifier_name': 'immunology', 'is_major_topic': True}, {'descriptor_ui': 'D015972', 'descriptor_name': 'Gene Expression Regulation, Neoplastic', 'qualifier_ui': 'Q000276', 'qualifier_name': 'immunology', 'is_major_topic': True}, {'descriptor_ui': 'D050503', 'descriptor_name': 'Indoleamine-Pyrrole 2,3,-Dioxygenase', 'qualifier_ui': 'Q000276', 'qualifier_name': 'immunology', 'is_major_topic': True}, {'descriptor_ui': 'D008223', 'descriptor_name': 'Lymphoma', 'qualifier_ui': 'Q000276', 'qualifier_name': 'immunology', 'is_major_topic': True}, {'descriptor_ui': 'D008264', 'descriptor_name': 'Macrophages', 'qualifier_ui': 'Q000276', 'qualifier_name': 'immunology', 'is_major_topic': True}, {'descriptor_ui': 'D017628', 'descriptor_name': 'Microglia', 'qualifier_ui': 'Q000276', 'qualifier_name': 'immunology', 'is_major_topic': True}, {'descriptor_ui': 'D009363', 'descriptor_name': 'Neoplasm Proteins', 'qualifier_ui': 'Q000276', 'qualifier_name': 'immunology', 'is_major_topic': True}, {'descriptor_ui': 'D019139', 'descriptor_name': 'Tumor Escape', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D060890', 'descriptor_name': 'B7-H1 Antigen', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D045744', 'descriptor_name': 'Cell Line, Tumor', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D016543', 'descriptor_name': 'Central Nervous System Neoplasms', 'qualifier_ui': 'Q000473', 'qualifier_name': 'pathology', 'is_major_topic': False}, {'descriptor_ui': 'D016543', 'descriptor_name': 'Central Nervous System Neoplasms', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005260', 'descriptor_name': 'Female', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015972', 'descriptor_name': 'Gene Expression Regulation, Neoplastic', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D050503', 'descriptor_name': 'Indoleamine-Pyrrole 2,3,-Dioxygenase', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008223', 'descriptor_name': 'Lymphoma', 'qualifier_ui': 'Q000473', 'qualifier_name': 'pathology', 'is_major_topic': False}, {'descriptor_ui': 'D008223', 'descriptor_name': 'Lymphoma', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008264', 'descriptor_name': 'Macrophages', 'qualifier_ui': 'Q000473', 'qualifier_name': 'pathology', 'is_major_topic': False}, {'descriptor_ui': 'D008264', 'descriptor_name': 'Macrophages', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008297', 'descriptor_name': 'Male', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D017628', 'descriptor_name': 'Microglia', 'qualifier_ui': 'Q000473', 'qualifier_name': 'pathology', 'is_major_topic': False}, {'descriptor_ui': 'D017628', 'descriptor_name': 'Microglia', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009363', 'descriptor_name': 'Neoplasm Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 4, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.3960/jslrt.18001', 'pdf_url': 'https://www.jstage.jst.go.jp/article/jslrt/58/2/58_18001/_pdf', 'source': {'id': 'https://openalex.org/S94741007', 'display_name': 'Journal of Clinical and Experimental Hematopathology', 'issn_l': '1346-4280', 'issn': ['1346-4280', '1880-9952'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': None, 'host_organization_name': None, 'host_organization_lineage': [], 'host_organization_lineage_names': [], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://europepmc.org/articles/pmc6413151', 'pdf_url': 'https://europepmc.org/articles/pmc6413151?pdf=render', 'source': {'id': 'https://openalex.org/S4306400806', 'display_name': 'Europe PMC (PubMed Central)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1303153112', 'host_organization_name': 'European Bioinformatics Institute', 'host_organization_lineage': ['https://openalex.org/I1303153112'], 'host_organization_lineage_names': ['European Bioinformatics Institute'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6413151', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/29998979', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.3960/jslrt.18001', 'pdf_url': 'https://www.jstage.jst.go.jp/article/jslrt/58/2/58_18001/_pdf', 'source': {'id': 'https://openalex.org/S94741007', 'display_name': 'Journal of Clinical and Experimental Hematopathology', 'issn_l': '1346-4280', 'issn': ['1346-4280', '1880-9952'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': None, 'host_organization_name': None, 'host_organization_lineage': [], 'host_organization_lineage_names': [], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [{'display_name': 'Good health and well-being', 'id': 'https://metadata.un.org/sdg/3', 'score': 0.85}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 32, 'referenced_works': ['https://openalex.org/W1766299275', 'https://openalex.org/W1949207081', 'https://openalex.org/W1973798835', 'https://openalex.org/W1990400836', 'https://openalex.org/W2040589111', 'https://openalex.org/W2051882232', 'https://openalex.org/W2095808484', 'https://openalex.org/W2115104447', 'https://openalex.org/W2133949144', 'https://openalex.org/W2152683795', 'https://openalex.org/W2160492423', 'https://openalex.org/W2230376335', 'https://openalex.org/W2347099355', 'https://openalex.org/W2513437047', 'https://openalex.org/W2560233848', 'https://openalex.org/W2570766240', 'https://openalex.org/W2590023130', 'https://openalex.org/W2595109242', 'https://openalex.org/W2595704927', 'https://openalex.org/W2600434382', 'https://openalex.org/W2600581432', 'https://openalex.org/W2610297465', 'https://openalex.org/W2617968907', 'https://openalex.org/W2724690266', 'https://openalex.org/W2730150905', 'https://openalex.org/W2741389799', 'https://openalex.org/W2774491730', 'https://openalex.org/W2782998220', 'https://openalex.org/W2785652708', 'https://openalex.org/W2979819244', 'https://openalex.org/W2982074880', 'https://openalex.org/W4253921737'], 'related_works': ['https://openalex.org/W4388495217', 'https://openalex.org/W4297013269', 'https://openalex.org/W3099369776', 'https://openalex.org/W3002759430', 'https://openalex.org/W2808686635', 'https://openalex.org/W2767753423', 'https://openalex.org/W2590244317', 'https://openalex.org/W2287464593', 'https://openalex.org/W2270388924', 'https://openalex.org/W1784648447'], 'abstract_inverted_index': {'Recent': [0], 'progress': [1], 'in': [2, 14, 30, 47, 80, 107, 160], 'anti-tumor': [3], 'immunotherapy': [4], 'has': [5], 'focused': [6], 'on': [7, 89], 'the': [8, 11, 34, 39, 90, 122, 134, 145], 'significance': [9], 'of': [10, 41, 70, 84, 92, 97, 124, 138, 147, 163], 'tumor': [12, 15], 'microenvironment': [13], 'progression': [16], 'and': [17, 58, 76, 95, 101, 110, 126, 153], 'resistance': [18], 'to': [19], 'chemo/radio-therapy.': [20], 'Myeloid': [21], 'cells': [22], 'such': [23], 'as': [24], 'macrophages': [25], 'are': [26], 'predominant': [27], 'stromal': [28], 'components': [29], 'hematological': [31], 'malignancies.': [32], 'In': [33], 'present': [35], 'study,': [36], 'we': [37], 'investigated': [38], 'regulation': [40], 'programmed': [42], 'death-1': [43], '(PD-1)': [44], 'ligand': [45], 'expression': [46, 83, 112, 117, 123, 146], 'primary': [48], 'central': [49], 'nervous': [50], 'system': [51], 'lymphoma': [52, 164], '(PCNSL)': [53], 'using': [54], 'PCNSL': [55, 63, 108], 'cell': [56, 64, 139], 'lines': [57], 'human': [59], 'monocyte-derived': [60], 'macrophages.': [61, 81], 'TK': [62], 'line-derived': [65], 'soluble': [66], 'factors': [67, 130], 'induced': [68], 'overexpression': [69], 'PD-1': [71, 85, 151], 'ligands,': [72], 'indoleamine': [73], '2,3-dioxygenase': [74], '(IDO1),': [75], 'several': [77], 'other': [78], 'cytokines': [79], 'The': [82], 'ligands': [86, 152], 'was': [87, 118], 'dependent': [88], 'activation': [91], 'signal': [93], 'transducer': [94], 'activator': [96], 'transcription': [98], '3.': [99], 'PD-L1': [100], 'IDO1': [102, 116], 'were': [103], 'overexpressed': [104], 'by': [105, 155], 'macrophage/microglia': [106, 156], 'tissues,': [109], 'gene': [111], 'profiling': [113], 'indicated': [114], 'that': [115, 144], 'positively': [119], 'correlated': [120], 'with': [121], 'macrophage': [125], 'lymphocyte': [127], 'markers.': [128], 'Macrophage-derived': [129], 'did': [131], 'not': [132], 'influence': [133], 'proliferation': [135], 'or': [136], 'chemo-sensitivity': [137], 'lines.': [140], 'These': [141], 'data': [142], 'suggest': [143], 'immunosuppressive': [148], 'molecules,': [149], 'including': [150], 'IDO1,': [154], 'may': [157], 'be': [158], 'involved': [159], 'immune': [161], 'evasion': [162], 'cells.': [165]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2845494217', 'counts_by_year': [{'year': 2024, 'cited_by_count': 3}, {'year': 2023, 'cited_by_count': 7}, {'year': 2022, 'cited_by_count': 10}, {'year': 2021, 'cited_by_count': 9}, {'year': 2020, 'cited_by_count': 7}, {'year': 2019, 'cited_by_count': 9}], 'updated_date': '2024-12-13T21:48:56.465574', 'created_date': '2018-07-19'}