Publication Information

{'id': 'https://openalex.org/W2811135594', 'doi': 'https://doi.org/10.1186/s12974-018-1239-9', 'title': 'The splenic response to stroke: from rodents to stroke subjects', 'display_name': 'The splenic response to stroke: from rodents to stroke subjects', 'publication_year': 2018, 'publication_date': '2018-07-03', 'ids': {'openalex': 'https://openalex.org/W2811135594', 'doi': 'https://doi.org/10.1186/s12974-018-1239-9', 'mag': '2811135594', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/29970193', 'pmcid': 'https://www.ncbi.nlm.nih.gov/pmc/articles/6030736'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1186/s12974-018-1239-9', 'pdf_url': 'https://jneuroinflammation.biomedcentral.com/track/pdf/10.1186/s12974-018-1239-9', 'source': {'id': 'https://openalex.org/S199572710', 'display_name': 'Journal of Neuroinflammation', 'issn_l': '1742-2094', 'issn': ['1742-2094'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320256', 'host_organization_name': 'BioMed Central', 'host_organization_lineage': ['https://openalex.org/P4310319965', 'https://openalex.org/P4310320256'], 'host_organization_lineage_names': ['Springer Nature', 'BioMed Central'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'review', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'doaj', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'gold', 'oa_url': 'https://jneuroinflammation.biomedcentral.com/track/pdf/10.1186/s12974-018-1239-9', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5019150773', 'display_name': 'Hilary Seifert', 'orcid': 'https://orcid.org/0000-0002-8187-4214'}, 'institutions': [{'id': 'https://openalex.org/I4210144745', 'display_name': 'VA Portland Health Care System', 'ror': 'https://ror.org/054484h93', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1322918889', 'https://openalex.org/I2799886695', 'https://openalex.org/I4210144745']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Hilary A. Seifert', 'raw_affiliation_strings': ['Neuroimmunology Research R&D-31 Veterans Affairs Portland Health Care System, 3710 SW US Veterans Hospital Rd, Portland, OR, 97239, USA'], 'affiliations': [{'raw_affiliation_string': 'Neuroimmunology Research R&D-31 Veterans Affairs Portland Health Care System, 3710 SW US Veterans Hospital Rd, Portland, OR, 97239, USA', 'institution_ids': ['https://openalex.org/I4210144745']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5087867695', 'display_name': 'Halina Offner', 'orcid': 'https://orcid.org/0000-0001-6472-6079'}, 'institutions': [{'id': 'https://openalex.org/I4210144745', 'display_name': 'VA Portland Health Care System', 'ror': 'https://ror.org/054484h93', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1322918889', 'https://openalex.org/I2799886695', 'https://openalex.org/I4210144745']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Halina Offner', 'raw_affiliation_strings': ['Neuroimmunology Research R&D-31 Veterans Affairs Portland Health Care System, 3710 SW US Veterans Hospital Rd, Portland, OR, 97239, USA'], 'affiliations': [{'raw_affiliation_string': 'Neuroimmunology Research R&D-31 Veterans Affairs Portland Health Care System, 3710 SW US Veterans Hospital Rd, Portland, OR, 97239, USA', 'institution_ids': ['https://openalex.org/I4210144745']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 1, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': {'value': 2390, 'currency': 'GBP', 'value_usd': 2931, 'provenance': 'doaj'}, 'apc_paid': {'value': 2390, 'currency': 'GBP', 'value_usd': 2931, 'provenance': 'doaj'}, 'fwci': 1.216, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 61, 'citation_normalized_percentile': {'value': 0.999519, 'is_in_top_1_percent': True, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 97, 'max': 98}, 'biblio': {'volume': '15', 'issue': '1', 'first_page': None, 'last_page': None}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T11266', 'display_name': 'Neuroinflammation and Neurodegeneration Mechanisms', 'score': 0.9927, 'subfield': {'id': 'https://openalex.org/subfields/2808', 'display_name': 'Neurology'}, 'field': {'id': 'https://openalex.org/fields/28', 'display_name': 'Neuroscience'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T11266', 'display_name': 'Neuroinflammation and Neurodegeneration Mechanisms', 'score': 0.9927, 'subfield': {'id': 'https://openalex.org/subfields/2808', 'display_name': 'Neurology'}, 'field': {'id': 'https://openalex.org/fields/28', 'display_name': 'Neuroscience'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T13551', 'display_name': 'Biochemical effects in animals', 'score': 0.9767, 'subfield': {'id': 'https://openalex.org/subfields/2737', 'display_name': 'Physiology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T11142', 'display_name': 'Advanced Glycation End Products research', 'score': 0.9617, 'subfield': {'id': 'https://openalex.org/subfields/1308', 'display_name': 'Clinical Biochemistry'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/stroke', 'display_name': 'Stroke', 'score': 0.919608}], 'concepts': [{'id': 'https://openalex.org/C2780645631', 'wikidata': 'https://www.wikidata.org/wiki/Q671554', 'display_name': 'Stroke (engine)', 'level': 2, 'score': 0.919608}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.7595584}, {'id': 'https://openalex.org/C16568411', 'wikidata': 'https://www.wikidata.org/wiki/Q83042', 'display_name': 'Neurology', 'level': 2, 'score': 0.67154545}, {'id': 'https://openalex.org/C2780931953', 'wikidata': 'https://www.wikidata.org/wiki/Q9371', 'display_name': 'Spleen', 'level': 2, 'score': 0.6580888}, {'id': 'https://openalex.org/C2776309230', 'wikidata': 'https://www.wikidata.org/wiki/Q580383', 'display_name': 'Splenectomy', 'level': 3, 'score': 0.45710075}, {'id': 'https://openalex.org/C8891405', 'wikidata': 'https://www.wikidata.org/wiki/Q1059', 'display_name': 'Immune system', 'level': 2, 'score': 0.4514047}, {'id': 'https://openalex.org/C2777094939', 'wikidata': 'https://www.wikidata.org/wiki/Q1368943', 'display_name': 'Intracerebral hemorrhage', 'level': 3, 'score': 0.41955066}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.35737455}, {'id': 'https://openalex.org/C203014093', 'wikidata': 'https://www.wikidata.org/wiki/Q101929', 'display_name': 'Immunology', 'level': 1, 'score': 0.24703276}, {'id': 'https://openalex.org/C2777736543', 'wikidata': 'https://www.wikidata.org/wiki/Q693442', 'display_name': 'Subarachnoid hemorrhage', 'level': 2, 'score': 0.15129086}, {'id': 'https://openalex.org/C118552586', 'wikidata': 'https://www.wikidata.org/wiki/Q7867', 'display_name': 'Psychiatry', 'level': 1, 'score': 0.05310273}, {'id': 'https://openalex.org/C78519656', 'wikidata': 'https://www.wikidata.org/wiki/Q101333', 'display_name': 'Mechanical engineering', 'level': 1, 'score': 0.0}, {'id': 'https://openalex.org/C127413603', 'wikidata': 'https://www.wikidata.org/wiki/Q11023', 'display_name': 'Engineering', 'level': 0, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D013154', 'descriptor_name': 'Spleen', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': True}, {'descriptor_ui': 'D020521', 'descriptor_name': 'Stroke', 'qualifier_ui': 'Q000276', 'qualifier_name': 'immunology', 'is_major_topic': True}, {'descriptor_ui': 'D020521', 'descriptor_name': 'Stroke', 'qualifier_ui': 'Q000473', 'qualifier_name': 'pathology', 'is_major_topic': True}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004195', 'descriptor_name': 'Disease Models, Animal', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D051379', 'descriptor_name': 'Mice', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D051381', 'descriptor_name': 'Rats', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013154', 'descriptor_name': 'Spleen', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013156', 'descriptor_name': 'Splenectomy', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D020521', 'descriptor_name': 'Stroke', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 4, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.1186/s12974-018-1239-9', 'pdf_url': 'https://jneuroinflammation.biomedcentral.com/track/pdf/10.1186/s12974-018-1239-9', 'source': {'id': 'https://openalex.org/S199572710', 'display_name': 'Journal of Neuroinflammation', 'issn_l': '1742-2094', 'issn': ['1742-2094'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320256', 'host_organization_name': 'BioMed Central', 'host_organization_lineage': ['https://openalex.org/P4310319965', 'https://openalex.org/P4310320256'], 'host_organization_lineage_names': ['Springer Nature', 'BioMed Central'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://doaj.org/article/2856ec08deaf4651a6abd219ec8caac0', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306401280', 'display_name': 'DOAJ (DOAJ: Directory of Open Access Journals)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': None, 'host_organization_name': None, 'host_organization_lineage': [], 'host_organization_lineage_names': [], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6030736', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/29970193', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1186/s12974-018-1239-9', 'pdf_url': 'https://jneuroinflammation.biomedcentral.com/track/pdf/10.1186/s12974-018-1239-9', 'source': {'id': 'https://openalex.org/S199572710', 'display_name': 'Journal of Neuroinflammation', 'issn_l': '1742-2094', 'issn': ['1742-2094'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320256', 'host_organization_name': 'BioMed Central', 'host_organization_lineage': ['https://openalex.org/P4310319965', 'https://openalex.org/P4310320256'], 'host_organization_lineage_names': ['Springer Nature', 'BioMed Central'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [{'id': 'https://metadata.un.org/sdg/1', 'score': 0.65, 'display_name': 'No poverty'}], 'grants': [{'funder': 'https://openalex.org/F4320306230', 'funder_display_name': 'American Heart Association', 'award_id': '17GRNT33220001'}, {'funder': 'https://openalex.org/F4320337359', 'funder_display_name': 'National Institute of Neurological Disorders and Stroke', 'award_id': 'R01NS076013'}, {'funder': 'https://openalex.org/F4320337359', 'funder_display_name': 'National Institute of Neurological Disorders and Stroke', 'award_id': 'R01NS080890'}], 'datasets': [], 'versions': [], 'referenced_works_count': 42, 'referenced_works': ['https://openalex.org/W1583337622', 'https://openalex.org/W1923630585', 'https://openalex.org/W1966194847', 'https://openalex.org/W1966545752', 'https://openalex.org/W1970341486', 'https://openalex.org/W1973879471', 'https://openalex.org/W1973921290', 'https://openalex.org/W1981160000', 'https://openalex.org/W1986677588', 'https://openalex.org/W1994363249', 'https://openalex.org/W2010929029', 'https://openalex.org/W2018131256', 'https://openalex.org/W2029939494', 'https://openalex.org/W2040579356', 'https://openalex.org/W2043790266', 'https://openalex.org/W2043880154', 'https://openalex.org/W2045780777', 'https://openalex.org/W2058367789', 'https://openalex.org/W2059050443', 'https://openalex.org/W2066004972', 'https://openalex.org/W2084147470', 'https://openalex.org/W2089263724', 'https://openalex.org/W2090641592', 'https://openalex.org/W2093416386', 'https://openalex.org/W2097756768', 'https://openalex.org/W2107091908', 'https://openalex.org/W2110566966', 'https://openalex.org/W2116505148', 'https://openalex.org/W2136067584', 'https://openalex.org/W2138451147', 'https://openalex.org/W2162787683', 'https://openalex.org/W2168286065', 'https://openalex.org/W2169980335', 'https://openalex.org/W2256195399', 'https://openalex.org/W2288310966', 'https://openalex.org/W2512205646', 'https://openalex.org/W2574367038', 'https://openalex.org/W2621513897', 'https://openalex.org/W2759715932', 'https://openalex.org/W2778313476', 'https://openalex.org/W2791453970', 'https://openalex.org/W79466244'], 'related_works': ['https://openalex.org/W3022420474', 'https://openalex.org/W2953399381', 'https://openalex.org/W2412544874', 'https://openalex.org/W2327174195', 'https://openalex.org/W2318572985', 'https://openalex.org/W2316898853', 'https://openalex.org/W2063031507', 'https://openalex.org/W2009445420', 'https://openalex.org/W2005546071', 'https://openalex.org/W1992327271'], 'abstract_inverted_index': {'Stroke': [0], 'is': [1, 28, 65, 147, 158, 183], 'the': [2, 9, 16, 29, 52, 96, 111, 115, 133, 145, 167, 171, 181, 194], 'fifth': [3], 'leading': [4, 10, 31], 'cause': [5, 11, 32], 'of': [6, 12, 33, 51, 62, 124, 141, 162, 170, 179], 'death': [7, 34], 'and': [8, 23, 35, 42, 64, 84, 89, 113, 204], 'long-term': [13], 'disability': [14], 'in': [15, 21, 40, 54, 59, 87, 99, 103, 110, 121, 136, 149, 153, 159, 173, 187, 198], 'USA,': [17], 'costing': [18], '$40.2': [19], 'billion': [20], 'direct': [22], 'indirect': [24], 'costs.': [25], 'Globally,': [26], 'stroke': [27, 55, 63, 86, 102, 125, 128, 137, 154, 174, 186, 207], 'second': [30], 'has': [36, 56], 'a': [37, 68, 150], 'higher': [38], 'prevalence': [39], 'lower-': [41], 'middle-income': [43], 'countries': [44], 'compared': [45], 'to': [46, 71, 82, 130], 'high-income': [47], 'countries.': [48], 'The': [49, 139], 'role': [50, 169], 'spleen': [53, 97, 112, 146, 172, 182], 'been': [57], 'studied': [58], 'rodent': [60], 'models': [61, 123, 161, 165], 'seen': [66], 'as': [67, 156], 'major': [69], 'contributor': [70], 'increased': [72, 109], 'secondary': [73], 'neural': [74], 'injury': [75], 'after': [76, 117], 'stroke.': [77, 118, 163], 'Splenectomy': [78], '2': [79], 'weeks': [80], 'prior': [81], 'ischemic': [83], 'hemorrhagic': [85], 'mice': [88], 'rats': [90], 'shows': [91], 'decreased': [92], 'infarct': [93], 'volumes.': [94], 'Additionally,': [95], 'decreases': [98], 'size': [100], 'following': [101], 'rodents.': [104], 'Pro-inflammatory': [105], 'mediators': [106], 'are': [107, 175], 'also': [108], 'subsequently': [114], 'brain': [116], 'These': [119], 'data': [120], 'preclinical': [122], 'have': [126], 'led': [127], 'neurologists': [129], 'look': [131], 'at': [132], 'splenic': [134, 195], 'response': [135, 197], 'subjects.': [138, 189, 208], 'outcomes': [140], 'these': [142], 'studies': [143], 'suggest': [144], 'responding': [148, 184], 'similar': [151], 'manner': [152], 'subjects': [155], 'it': [157], 'animal': [160], 'Animal': [164], 'demonstrating': [166], 'detrimental': [168], 'providing': [176], 'strong': [177], 'evidence': [178], 'how': [180], 'during': [185], 'human': [188], 'This': [190], 'indicates': [191], 'treatments': [192, 205], 'targeting': [193], 'immune': [196], 'animals': [199], 'could': [200], 'provide': [201], 'useful': [202], 'targets': [203], 'for': [206]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2811135594', 'counts_by_year': [{'year': 2024, 'cited_by_count': 5}, {'year': 2023, 'cited_by_count': 10}, {'year': 2022, 'cited_by_count': 15}, {'year': 2021, 'cited_by_count': 11}, {'year': 2020, 'cited_by_count': 7}, {'year': 2019, 'cited_by_count': 13}, {'year': 2018, 'cited_by_count': 1}], 'updated_date': '2024-12-18T07:51:08.445630', 'created_date': '2018-07-10'}