Title: Landscape of somatic genetic alterations in endometrioid endometrial cancers with germline and somatic PTEN mutations
Abstract: Objective: Germline PTEN mutations result in a spectrum of autosomal dominant hamartomatous tumor syndromes, most notably Cowden syndrome. Here we sought to determine the repertoire of somatic genetic alterations of an endometrioid endometrial cancer from a germline PTEN mutation carrier with Cowden syndrome, and to compare its genomic profile to that of endometrial cancers arising in patients with somatic PTEN mutations.
Publication Year: 2018
Publication Date: 2018-06-01
Language: en
Type: article
Indexed In: ['crossref']
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