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'included': [633, 794], 'all': [634, 786], '(myocardial': [638], 'infarction,': [639], 'resuscitated': [640], 'cardiac': [641], 'arrest,': [642], 'death),': [645], 'plus': [646], 'stroke': [647, 649], 'death.': [650], 'Participants': [651, 838], 'provided': [652], 'informed': [653], 'consent,': [654], 'each': [656], 'site': [658], 'obtained': [659], 'approval': [660], 'from': [661, 1166, 1441, 1455, 2016], 'their': [662, 1405], 'institutional': [663], 'review': [664], 'board.Cox': [665], 'proportional': [666, 1303], 'hazard': [667, 673, 1304, 1388], 'models': [668, 945, 1018], 'developed': [670, 1464], 'calculate': [672], 'ratios': [674, 1305], 'by': [678, 728, 834, 1009, 1298, 1314, 1319, 1427, 1450, 1476, 1489, 1524, 2244, 3280, 3318, 3352], 'status': [680], '(ED': [681], 'yes/no)': [682], 'after': [683, 1042], 'adjusting': [684, 693, 721, 800], 'age,': [686, 1326], 'race/ethnicity,': [687], 'education': [689], '(model': [690, 717, 744, 946], '1);': [691], 'further': [692, 720, 746], 'smoking': [695, 1337], 'status,': [696, 1338], 'family': [699, 850, 1341], 'history': [700, 851, 1342], 'CHD,': [702, 1344], 'total/high-density': [703], 'lipoprotein': [704], 'cholesterol': [705, 1346], 'ratio,': [706, 926, 936, 958, 998, 1020, 1347], 'systolic': [707, 1348], 'blood': [708, 1349], 'pressure,': [709, 1350], 'antihypertensive': [710, 1351], 'medication': [711, 715, 1010, 1352, 1356], 'use,': [712, 1353], 'lipid-lowering': [714, 1355], 'use': [716, 724, 860, 1011, 1644], '2);': [718], 'β-blocker': [723, 1051, 1071, 1367], 'depression': [726, 1013, 1069, 1365], 'assessed': [727], 'Epidemiological': [732, 738], 'Studies': [733, 739], 'Depression': [734, 740], 'score': [735, 1148], '(Center': [736], 'score>16': [741], 'versus': [742, 902, 909], '≤16)': [743], '3).To': [745], 'assess': [747], 'potential': [749], 'bidirectional': [750], 'relationship': [751, 1084], 'prior': [753, 989, 1086], 'ED,': [756, 1090, 1194, 1211, 1380], 'additional': [758, 1231], 'shifted-time': [759, 979], 'cross-sectional': [760, 980], 'conducted': [763], 'see': [765], 'interim': [768], 'associated': [776, 2919], '5.': [782], 'For': [783], 'analysis,': [785, 981], '1914': [787, 809], 'assessment': [792, 1192], 'multivariable-adjusted': [797], 'logistic': [798], 'regression': [799], 'above-mentioned': [803], 'covariates.The': [804], 'mean': [805], 'age': [806], '69±9.2': [812], '42.3%': [815], 'white,': [817], '24.2%': [818], 'African': [820], 'American,': [821, 825], '10.5%': [822], 'Chinese': [824], '22.9%': [827], 'Hispanic.': [829], 'reported': [833], '877': [835], '(45.8%)': [836], 'participants.': [837, 1283], 'more': [842, 857, 1175], 'likely': [843, 858], 'mellitus': [847], 'CHD.': [853], 'They': [854], 'β-blocker,': [861], 'antihypertensive,': [862], 'lipid-lowering,': [863], 'antidepressant': [865], 'medications.': [866], 'Over': [867], '3.8-year': [869], 'follow-up,': [870], 'there': [871], 'total': [874], '40': [876, 1865, 2727], '75': [879], 'events.': [882, 940], 'significantly': [884], 'greater': [885, 1798], 'proportion': [886], 'experienced': [891], 'than': [894], 'without': [896], '(CHD': [898], 'events:': [900, 907, 1804, 2066], '3.4%': [901], '1.4%,': [903], 'P<0.001;': [904], '6.3%': [908], '2.6%,': [910], 'P<0.001).In': [911], 'unadjusted': [913], 'Cox': [914, 1302], 'models,': [915], 'significant': [919, 951, 983, 1005, 1036], 'both': [922], '(hazard': [925, 935, 957], '2.5;': [927], '95%': [928, 938, 960, 1000, 1022], 'confidence': [929, 1375], 'interval': [930], '[CI],': [931], '1.3–4.8)': [932], '2.6;': [937], 'CI,1.6–4.1)': [939], 'In': [941, 1143, 1222, 2382], 'fully': [943, 1016], 'adjusted': [944, 1017, 1067, 1324, 1332, 1360], '3),': [947], 'remained': [949, 1004], '1.9;': [959], 'CI,': [961, 1001, 1023, 1374], '1.1–3.4),': [962], 'whereas': [963], 'became': [967], 'nonsignificant,': [968], 'albeit': [969], 'similar': [972, 1187], 'point': [973], 'estimate': [974, 1722], '(Figure).In': [977], 'association': [984, 1097, 1112, 1217], 'seen': [987], 'between': [988, 1085, 1113, 1205, 1218, 1270, 1841, 1877], '(odds': [997, 1019], '2.1;': [999], '1.4–3.2),': [1002], 'which': [1003, 1212], 'but': [1006, 1091], 'attenuated': [1008, 1215], '1.7;': [1021], '1.1–2.6).In': [1024], 'community-based': [1028], 'cohort,': [1029], 'found': [1032, 1419], 'be': [1034, 1418], 'adjustment': [1043], 'traditional': [1045, 1761], 'factors,': [1048], 'depression,': [1049], 'use.': [1052, 1072, 1357, 1368], 'To': [1053], 'knowledge,': [1055], 'first': [1059, 1151], 'subsequent': [1064, 1089, 1692], 'that': [1066, 1076], 'Our': [1073, 1103, 1171], 'results': [1074, 1172], 'suggest': [1075], '2': [1078, 1331, 1363], 'may': [1080, 1173, 1213], 'partially': [1081], 'mediate': [1082], 'do': [1092], 'not': [1093, 1203, 1485, 1508], 'attenuate': [1094], 'CVD.': [1102, 1221], 'findings': [1104], 'strengthen': [1105], 'existing': [1107], 'CVD,': [1117, 1377], 'could': [1119], 'important': [1121], 'clinical': [1122, 2681], 'implications': [1123], 'stratification': [1126], 'middle-aged': [1128], 'men.': [1129], 'We': [1130], 'previously': [1132], 'documented': [1133], 'increased': [1134], 'subclinical': [1135], 'atherosclerosis': [1136], 'subsequently': [1140], 'report': [1141], 'ED.4': [1142], '2017,': [1144], 'UK': [1146], 'QRISK': [1147], 'incorporate': [1153], 'factor': [1159], 'CVD,5': [1161], 'yet': [1162], 'remains': [1164], 'absent': [1165], 'US': [1167, 1478], 'prediction': [1169, 1719, 2063], 'guidelines.': [1170], 'justify': [1174], 'aggressive': [1176], 'preventive': [1177], 'therapy': [1178], 'such': [1180], 'patients.Our': [1181], 'had': [1183], 'certain': [1184], 'limitations.': [1185], 'Although': [1186], 'primary': [1190], 'care': [1191], 'question': [1201, 1648], 'does': [1202, 1507], 'distinguish': [1204], 'vascular': [1206, 1689], 'nonvascular': [1208], 'types': [1209], 'addition,': [1223], 'because': [1224], 'follow-up': [1226], 'just': [1228], 'years,': [1230], '10-year': [1232], 'data': [1233, 1521], 'predictive': [1237, 1257], 'needed.In': [1242], 'conclusion,': [1243], 'provides': [1246], 'some': [1247], 'strongest': [1250], 'date': [1253], 'modern,': [1263], 'multiethnic,': [1264], 'well-phenotyped': [1265], 'cohort.Download': [1266], 'figureDownload': [1267], 'PowerPointFigure.': [1268], 'Association': [1269, 1840, 1969, 2504, 2803, 2875, 3189], 'among': [1279], 'male': [1281, 2439], 'B,': [1286, 2279], 'Kaplan-Meier': [1287], 'cumulative': [1288], 'survival': [1289], 'function': [1290], 'curves': [1291], 'status.': [1300, 1316], 'C,': [1301, 1710, 1744, 2275, 2759, 2829, 2954, 3016, 3106, 3118, 3120], '(95%': [1306], 'CIs)': [1307], '*P': [1317], 'log-rank': [1320], 'testing.': [1321], '†Model': [1322], '1': [1323, 1335], 'race/ethnicity': [1327], 'education.': [1329], '‡Model': [1330], 'model': [1334, 1362], '+': [1336, 1364], 'total/HDL': [1345], '§Model': [1358], '3': [1359], 'indicates': [1370], 'disease;': [1373, 1379], 'interval;': [1376], 'dysfunction;': [1382], 'HDL,': [1383], 'high-density': [1384], 'lipoprotein;': [1385], 'HR,': [1387], 'ratio.AcknowledgmentsThe': [1389], 'authors': [1390, 1503], 'thank': [1391], 'other': [1393], 'investigators,': [1394], 'staff,': [1396], 'valuable': [1406], 'contributions.': [1407], 'full': [1409], 'list': [1410], 'participating': [1412], 'investigators': [1414], 'institutions': [1416], 'can': [1417], 'http://www.mesa-nhlbi.org.Sources': [1421], 'FundingThis': [1423], 'research': [1424, 1468], 'supported': [1426], 'contracts': [1428], 'N01-HC-95159,': [1429], 'N01-HC-95160,': [1430], 'N01-HC-95161,': [1431], 'N01-HC-95162,': [1432], 'N01-HC-95163,': [1433], 'N01-HC-95164,': [1434], 'N01-HC-95165,': [1435], 'N01-HC-95166,': [1436], 'N01-HC-95167,': [1437], 'N01-HC-95168': [1438], 'N01-HC-95169': [1440], 'National': [1443, 1456, 2901], 'Heart,': [1444], 'Lung,': [1445], 'Blood': [1447], 'grants': [1451], 'UL1-TR-000040,': [1452], 'UL1-TR-001079': [1454], 'Resources.': [1460], 'This': [1461], 'publication': [1462, 1892, 1938, 1992, 2032, 2079, 2095, 2123, 2210, 2314, 2335, 2417, 2449, 2483, 2527, 2558, 2605, 2663, 2691, 2743, 2814, 2886, 2938, 3000, 3064, 3100, 3145, 3164, 3211, 3268, 3307, 3343, 3377, 3416, 3444, 3462], 'under': [1465], 'STAR': [1467], 'assistance': [1469], 'agreement,': [1470], 'RD831697': [1472], '(MESA': [1473], 'Air),': [1474], 'awarded': [1475], 'Environmental': [1479], 'Protection': [1480], 'Agency': [1481], '(EPA).': [1482], 'It': [1483, 3425], 'has': [1484], 'formally': [1487], 'reviewed': [1488], 'EPA.': [1491], 'views': [1493], 'expressed': [1494], 'document': [1497], 'solely': [1499], 'EPA': [1506], 'endorse': [1509], 'any': [1510], 'products': [1511], 'commercial': [1513], 'services': [1514], 'mentioned': [1515], 'publication.DisclosuresNone.FootnotesData': [1518], 'sharing:': [1519], 'available': [1523], 'request': [1525], 'website': [1529], 'https://www.mesa-nhlbi.org/.https://www.ahajournals.org/journal/circMichael': [1531], 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'Rodriguez‐Agurto': [1784], 'Bravo': [1787], 'M': [1788, 1967, 2176, 2462, 2672, 3233, 3277], 'Patients': [1790, 1916, 2242], 'periodontitis': [1792], 'suffer': [1796], 'incidence': [1799], 'major': [1801, 2590], 'adverse': [1802, 2591], 'Spanish': [1810], 'population,': [1811], 'Periodontology,': [1814], '10.1002/JPER.21-0477': [1815], 'Fujita': [1816], 'N,': [1817, 1869, 2281, 2421, 2491, 3108, 3116, 3381, 3387], 'Hatakeyama': [1818], 'Momota': [1820], 'Tobisawa': [1822], 'Y,': [1823, 1833, 2487], 'Yoneyama': [1824, 1830], 'T,': [1825, 1827, 1831, 1944, 1962, 2285, 3068], 'Okamoto': [1826], 'Yamamoto': [1828], 'H,': [1829, 2283, 2709], 'Hashimoto': [1832], 'Yoshikawa': [1834], 'K': [1835, 1871, 2568], 'Ohyama': [1837], 'C': [1838, 1874, 3398], 'Aortic': [1842], 'Calcification': [1843], 'Burden': [1844], 'Severity': [1847], 'Men': [1852, 2151, 2181, 2726, 3252], 'Undergoing': [1853], 'Dialysis:': [1854], 'Cross-Sectional': [1856, 2634, 3257], 'Study,': [1857, 1982, 2635, 3258], 'World': [1859], "Men's": [1862, 3262], '10.5534/wjmh.210230,': [1864], 'Terentes-Printzios': [1866], 'Ioakeimidis': [1868], 'Rokkas': [1870], 'Vlachopoulos': [1873], '(2021)': [1875, 2005, 2050, 2087, 2109, 2147, 2177, 2196, 2230, 2295, 2319, 2345, 2363], 'Interactions': [1876], 'drugs,': [1884], 'Nature': [1885], 'Reviews': [1886], '10.1038/s41569-021-00593-6,': [1888], '19:1,': [1889, 1935, 2077], '(59-74),': [1890], 'Online': [1891, 1937, 1991, 2031, 2078, 2094, 2122, 2209, 2313, 2334, 2416, 2448, 2482, 2526, 2557, 2604, 2662, 2690, 2742, 2813, 2885, 2937, 2999, 3063, 3099, 3144, 3163, 3210, 3267, 3306, 3342, 3376, 3415, 3443, 3461], 'date:': [1893, 1939, 1993, 2033, 2080, 2096, 2124, 2211, 2315, 2336, 2418, 2450, 2484, 2528, 2559, 2606, 2664, 2692, 2744, 2815, 2887, 2939, 3001, 3065, 3101, 3146, 3165, 3212, 3269, 3308, 3344, 3378, 3417, 3445, 3463], '1-Jan-2022.': [1894, 1940, 1994, 2034], 'Nunes': [1895], 'Seeger': [1897], 'J,': [1898, 2129, 2265, 2269, 2489, 2609, 2695, 2699, 2705, 2765, 2835, 2960, 3022, 3072, 3219], 'Stewart': [1899], 'Gupta': [1901], 'McGraw': [1904], 'T': [1905, 2108, 2401, 2899, 3184, 3448], 'Retrospective': [1907], 'Observational': [1908], 'Real-World': [1909], 'Outcome': [1910], 'Evaluate': [1913], 'Safety': [1914], 'Among': [1915], 'With': [1917, 1921, 1972, 3253], 'Co-Possession': [1922], 'Tadalafil': [1924], 'Anti-Hypertensive': [1926], 'Medications': [1927], '(anti-HTN),': [1928], 'Sexual': [1932, 2404, 2410, 2737, 3128, 3430], '10.1016/j.jsxm.2021.10.012,': [1934], '(74-82),': [1936], 'El-Shahawy': [1941], 'O,': [1942, 1946, 1999, 2667], 'Shah': [1943, 2280], 'Obisesan': [1945], 'Durr': [1947], 'Stokes': [1949], 'I,': [1952, 2890], 'Pinjani': [1953], 'Benjamin': [1955], 'E,': [1956, 2139, 2261, 2497, 2531, 2757, 2767, 2827, 2837, 2952, 2962, 3014, 3024, 3168], 'Osei': [1959], 'Loney': [1961], 'Sherman': [1963], 'S': [1964, 2318, 2426, 2499, 2611, 2614, 3420, 3423], 'E-Cigarettes': [1971], 'Dysfunction:': [1974, 2298, 2632], 'Population': [1976], 'Assessment': [1977], 'Tobacco': [1979], 'American': [1983, 2306, 2519, 2798, 2870, 2992, 3056, 3259, 3476], '10.1016/j.amepre.2021.08.004,': [1988], '62:1,': [1989], '(26-38),': [1990], 'Idowu': [1995], 'Oyeleye': [1996], 'Ajayi': [1998], 'Ademosun': [2000], 'Oboh': [2003], 'G': [2004, 2173], 'GC': [2006], 'characterization': [2007], 'erectogenic': [2009], 'enzyme': [2010], 'inhibitory': [2011], 'effect': [2012], 'essential': [2014], 'oils': [2015], 'tangerine': [2017], 'lemon': [2019], 'peels:': [2020], 'comparative': [2022], 'Flavour': [2024], 'Fragrance': [2026], 'Journal,': [2027], '10.1002/ffj.3679,': [2028], '37:1,': [2029], '(33-42),': [2030], 'Hadaegh': [2035], 'Asgari': [2037], 'Moosaie': [2039], 'Orangi': [2041], 'Sarvghadi': [2043], 'Khalili': [2045], 'D': [2046, 2291, 2669, 3236], 'Azizi': [2048], 'added': [2054], 'values': [2055], 'atherosclerotic': [2058], 'enhancers': [2061], 'Tehran': [2067], 'lipid': [2068], 'glucose': [2070], 'Translational': [2074], '10.1186/s12967-020-02686-1,': [2076], '1-Dec-2021.': [2081, 2097], 'Mohan': [2082, 2358, 2644], 'V': [2083, 2359, 2372, 2645], 'Diehm': [2085, 2361, 2647], 'Erektile': [2088, 2364, 2650], 'Dysfunktion,': [2089], 'CardioVasc,': [2090, 2658], '10.1007/s15027-021-3581-6,': [2091], '21:6,': [2092], '(53-58),': [2093], 'Clephane': [2098], 'Wilson': [2100], 'Craig': [2102], 'Heiman': [2104], 'Lorenz': [2107], 'Inflammation': [2110], 'predicts': [2111, 3403], 'sexual': [2112], 'arousability': [2113], 'healthy': [2115], 'women,': [2116], 'Comprehensive': [2117], 'Psychoneuroendocrinology,': [2118], '10.1016/j.cpnec.2021.100086,': [2119], '8,': [2120], '(100086),': [2121], '1-Nov-2021.': [2125], 'Kałka': [2126, 3235], 'Gebala': [2128, 3218], 'Biernikiewicz': [2130], 'Mrozek-Szetela': [2132], 'Rożek-Piechura': [2134], 'Sobieszczańska': [2136, 3220], 'Szuster': [2138], 'Majchrowska': [2140], 'Miętka': [2142], 'Rusiecka': [2145], 'Burdened': [2152], 'Familial': [2155], 'Occurrence': 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2793, 2863, 3050], 'Review,': [2249], 'Biomedicines,': [2250], '10.3390/biomedicines9040432,': [2251], '9:4,': [2252], '(432)': [2253], 'Ostfeld': [2254], 'Allen': [2256, 2490], 'Aspry': [2258], 'Brandt': [2260], 'Spitz': [2262], 'Liberman': [2264], 'Belardo': [2266], "O'Keefe": [2268], 'Aggarwal': [2270], 'Batiste': [2274], 'Kopecky': [2276], 'White': [2278], 'Hawamdeh': [2282], 'Batts': [2284], 'Reddy': [2288], 'Ornish': [2290], 'Freeman': [2293], 'Vasculogenic': [2296], 'Impact': [2300], 'Diet': [2302], 'Lifestyle,': [2304], '10.1016/j.amjmed.2020.09.033,': [2310], '134:3,': [2311], '(310-316),': [2312], '1-Mar-2021.': [2316], 'Agarwal': [2317], 'Exercise': [2320], 'Holistic': [2329], '10.18231/j.jpmhh.2020.011,': [2331], '6:2,': [2332], '(54-61),': [2333], '28-Feb-2021.': [2337], 'Sharma': [2338], 'Minhas': [2340], 'Michos': [2343, 2496, 2766, 2836, 2961, 3023], 'Disease': [2349], 'Sex': [2350], 'Differences': [2351], 'Diseases,': [2354], '10.1016/B978-0-12-819369-3.00013-7,': 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