Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2807736360', 'doi': 'https://doi.org/10.1208/s12249-018-1091-3', 'title': 'Application of FT-NIR Analysis for In-line and Real-Time Monitoring of Pharmaceutical Hot Melt Extrusion: a Technical Note', 'display_name': 'Application of FT-NIR Analysis for In-line and Real-Time Monitoring of Pharmaceutical Hot Melt Extrusion: a Technical Note', 'publication_year': 2018, 'publication_date': '2018-06-13', 'ids': {'openalex': 'https://openalex.org/W2807736360', 'doi': 'https://doi.org/10.1208/s12249-018-1091-3', 'mag': '2807736360', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/29948985', 'pmcid': 'https://www.ncbi.nlm.nih.gov/pmc/articles/6283664'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1208/s12249-018-1091-3', 'pdf_url': 'https://link.springer.com/content/pdf/10.1208/s12249-018-1091-3.pdf', 'source': {'id': 'https://openalex.org/S1234972', 'display_name': 'AAPS PharmSciTech', 'issn_l': '1530-9932', 'issn': ['1530-9932'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310319900', 'host_organization_name': 'Springer Science+Business Media', 'host_organization_lineage': ['https://openalex.org/P4310319965', 'https://openalex.org/P4310319900'], 'host_organization_lineage_names': ['Springer Nature', 'Springer Science+Business Media'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'bronze', 'oa_url': 'https://link.springer.com/content/pdf/10.1208/s12249-018-1091-3.pdf', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5020755160', 'display_name': 'Anh Q. Vo', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I368840534', 'display_name': 'University of Mississippi', 'ror': 'https://ror.org/02teq1165', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I368840534', 'https://openalex.org/I4210141039']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Anh Q. Vo', 'raw_affiliation_strings': ['Department of Pharmaceutics and Drug Delivery, University of Mississippi, University, Mississippi, 38677, USA'], 'affiliations': [{'raw_affiliation_string': 'Department of Pharmaceutics and Drug Delivery, University of Mississippi, University, Mississippi, 38677, USA', 'institution_ids': ['https://openalex.org/I368840534']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5021220202', 'display_name': 'Herman He', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210142480', 'display_name': 'Thermo Fisher Scientific (United States)', 'ror': 'https://ror.org/03x1ewr52', 'country_code': 'US', 'type': 'company', 'lineage': ['https://openalex.org/I4210142480']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Herman He', 'raw_affiliation_strings': ['Thermo Fisher Scientific, Waltham, Massachusetts, USA'], 'affiliations': [{'raw_affiliation_string': 'Thermo Fisher Scientific, Waltham, Massachusetts, USA', 'institution_ids': ['https://openalex.org/I4210142480']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5100608005', 'display_name': 'Jiaxiang Zhang', 'orcid': 'https://orcid.org/0000-0002-5402-9277'}, 'institutions': [{'id': 'https://openalex.org/I368840534', 'display_name': 'University of Mississippi', 'ror': 'https://ror.org/02teq1165', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I368840534', 'https://openalex.org/I4210141039']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Jiaxiang Zhang', 'raw_affiliation_strings': ['Department of Pharmaceutics and Drug Delivery, University of Mississippi, University, Mississippi, 38677, USA'], 'affiliations': [{'raw_affiliation_string': 'Department of Pharmaceutics and Drug Delivery, University of Mississippi, University, Mississippi, 38677, USA', 'institution_ids': ['https://openalex.org/I368840534']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5057688043', 'display_name': 'S. T. Martin', 'orcid': 'https://orcid.org/0000-0003-1073-3358'}, 'institutions': [{'id': 'https://openalex.org/I4210142480', 'display_name': 'Thermo Fisher Scientific (United States)', 'ror': 'https://ror.org/03x1ewr52', 'country_code': 'US', 'type': 'company', 'lineage': ['https://openalex.org/I4210142480']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Scott Martin', 'raw_affiliation_strings': ['Thermo Fisher Scientific, Waltham, Massachusetts, USA'], 'affiliations': [{'raw_affiliation_string': 'Thermo Fisher Scientific, Waltham, Massachusetts, USA', 'institution_ids': ['https://openalex.org/I4210142480']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5100403653', 'display_name': 'Rui Chen', 'orcid': 'https://orcid.org/0000-0002-6488-6133'}, 'institutions': [{'id': 'https://openalex.org/I4210142480', 'display_name': 'Thermo Fisher Scientific (United States)', 'ror': 'https://ror.org/03x1ewr52', 'country_code': 'US', 'type': 'company', 'lineage': ['https://openalex.org/I4210142480']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Rui Chen', 'raw_affiliation_strings': ['Thermo Fisher Scientific, Waltham, Massachusetts, USA'], 'affiliations': [{'raw_affiliation_string': 'Thermo Fisher Scientific, Waltham, Massachusetts, USA', 'institution_ids': ['https://openalex.org/I4210142480']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5035421570', 'display_name': 'Michael A. Repka', 'orcid': 'https://orcid.org/0000-0003-2049-4696'}, 'institutions': [{'id': 'https://openalex.org/I368840534', 'display_name': 'University of Mississippi', 'ror': 'https://ror.org/02teq1165', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I368840534', 'https://openalex.org/I4210141039']}], 'countries': ['US'], 'is_corresponding': True, 'raw_author_name': 'Michael A. Repka', 'raw_affiliation_strings': ['Pii Center for Pharmaceutical Technology, School of Pharmacy, University of Mississippi, University, Mississippi, 38677, USA'], 'affiliations': [{'raw_affiliation_string': 'Pii Center for Pharmaceutical Technology, School of Pharmacy, University of Mississippi, University, Mississippi, 38677, USA', 'institution_ids': ['https://openalex.org/I368840534']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 2, 'corresponding_author_ids': ['https://openalex.org/A5035421570'], 'corresponding_institution_ids': ['https://openalex.org/I368840534'], 'apc_list': {'value': 2890, 'currency': 'EUR', 'value_usd': 3690, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 3.423, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 29, 'citation_normalized_percentile': {'value': 0.999784, 'is_in_top_1_percent': True, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 93, 'max': 94}, 'biblio': {'volume': '19', 'issue': '8', 'first_page': '3425', 'last_page': '3429'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10640', 'display_name': 'Chemometrics in Analytical Chemistry and Food Technology', 'score': 0.9998, 'subfield': {'id': 'https://openalex.org/subfields/1602', 'display_name': 'Analytical Chemistry'}, 'field': {'id': 'https://openalex.org/fields/16', 'display_name': 'Chemistry'}, 'domain': {'id': 'https://openalex.org/domains/3', 'display_name': 'Physical Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10640', 'display_name': 'Chemometrics in Analytical Chemistry and Food Technology', 'score': 0.9998, 'subfield': {'id': 'https://openalex.org/subfields/1602', 'display_name': 'Analytical Chemistry'}, 'field': {'id': 'https://openalex.org/fields/16', 'display_name': 'Chemistry'}, 'domain': {'id': 'https://openalex.org/domains/3', 'display_name': 'Physical Sciences'}}, {'id': 'https://openalex.org/T11324', 'display_name': 'Biomedical Applications of Spectroscopy Techniques', 'score': 0.9912, 'subfield': {'id': 'https://openalex.org/subfields/1304', 'display_name': 'Biophysics'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10876', 'display_name': 'Process Fault Detection and Diagnosis in Industries', 'score': 0.9775, 'subfield': {'id': 'https://openalex.org/subfields/2207', 'display_name': 'Control and Systems Engineering'}, 'field': {'id': 'https://openalex.org/fields/22', 'display_name': 'Engineering'}, 'domain': {'id': 'https://openalex.org/domains/3', 'display_name': 'Physical Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/process-analytical-technology', 'display_name': 'Process analytical technology', 'score': 0.9241941}, {'id': 'https://openalex.org/keywords/pharmaceutical-manufacturing', 'display_name': 'Pharmaceutical manufacturing', 'score': 0.6760587}, {'id': 'https://openalex.org/keywords/chemometrics', 'display_name': 'Chemometrics', 'score': 0.54694706}, {'id': 'https://openalex.org/keywords/process-monitoring', 'display_name': 'Process Monitoring', 'score': 0.544253}, {'id': 'https://openalex.org/keywords/near-infrared-spectroscopy', 'display_name': 'Near-Infrared Spectroscopy', 'score': 0.527148}], 'concepts': [{'id': 'https://openalex.org/C178144697', 'wikidata': 'https://www.wikidata.org/wiki/Q2111609', 'display_name': 'Process analytical technology', 'level': 3, 'score': 0.9241941}, {'id': 'https://openalex.org/C2778958987', 'wikidata': 'https://www.wikidata.org/wiki/Q139143', 'display_name': 'Extrusion', 'level': 2, 'score': 0.7741026}, {'id': 'https://openalex.org/C21880701', 'wikidata': 'https://www.wikidata.org/wiki/Q2144042', 'display_name': 'Process engineering', 'level': 1, 'score': 0.69608927}, {'id': 'https://openalex.org/C2778938233', 'wikidata': 'https://www.wikidata.org/wiki/Q7180757', 'display_name': 'Pharmaceutical manufacturing', 'level': 2, 'score': 0.6760587}, {'id': 'https://openalex.org/C151304367', 'wikidata': 'https://www.wikidata.org/wiki/Q910067', 'display_name': 'Chemometrics', 'level': 2, 'score': 0.54694706}, {'id': 'https://openalex.org/C98045186', 'wikidata': 'https://www.wikidata.org/wiki/Q205663', 'display_name': 'Process (computing)', 'level': 2, 'score': 0.5124879}, {'id': 'https://openalex.org/C43571822', 'wikidata': 'https://www.wikidata.org/wiki/Q599037', 'display_name': 'Near-infrared spectroscopy', 'level': 2, 'score': 0.4659444}, {'id': 'https://openalex.org/C160892712', 'wikidata': 'https://www.wikidata.org/wiki/Q901559', 'display_name': 'Fourier transform infrared spectroscopy', 'level': 2, 'score': 0.45241708}, {'id': 'https://openalex.org/C45904493', 'wikidata': 'https://www.wikidata.org/wiki/Q912807', 'display_name': 'Active ingredient', 'level': 2, 'score': 0.43437272}, {'id': 'https://openalex.org/C192562407', 'wikidata': 'https://www.wikidata.org/wiki/Q228736', 'display_name': 'Materials science', 'level': 0, 'score': 0.390388}, {'id': 'https://openalex.org/C41008148', 'wikidata': 'https://www.wikidata.org/wiki/Q21198', 'display_name': 'Computer science', 'level': 0, 'score': 0.38628405}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.25945735}, {'id': 'https://openalex.org/C174998907', 'wikidata': 'https://www.wikidata.org/wiki/Q357662', 'display_name': 'Work in process', 'level': 2, 'score': 0.20991853}, {'id': 'https://openalex.org/C43617362', 'wikidata': 'https://www.wikidata.org/wiki/Q170050', 'display_name': 'Chromatography', 'level': 1, 'score': 0.19871727}, {'id': 'https://openalex.org/C42360764', 'wikidata': 'https://www.wikidata.org/wiki/Q83588', 'display_name': 'Chemical engineering', 'level': 1, 'score': 0.13630477}, {'id': 'https://openalex.org/C127413603', 'wikidata': 'https://www.wikidata.org/wiki/Q11023', 'display_name': 'Engineering', 'level': 0, 'score': 0.104210794}, {'id': 'https://openalex.org/C120665830', 'wikidata': 'https://www.wikidata.org/wiki/Q14620', 'display_name': 'Optics', 'level': 1, 'score': 0.10321158}, {'id': 'https://openalex.org/C60644358', 'wikidata': 'https://www.wikidata.org/wiki/Q128570', 'display_name': 'Bioinformatics', 'level': 1, 'score': 0.0}, {'id': 'https://openalex.org/C21547014', 'wikidata': 'https://www.wikidata.org/wiki/Q1423657', 'display_name': 'Operations management', 'level': 1, 'score': 0.0}, {'id': 'https://openalex.org/C121332964', 'wikidata': 'https://www.wikidata.org/wiki/Q413', 'display_name': 'Physics', 'level': 0, 'score': 0.0}, {'id': 'https://openalex.org/C191897082', 'wikidata': 'https://www.wikidata.org/wiki/Q11467', 'display_name': 'Metallurgy', 'level': 1, 'score': 0.0}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.0}, {'id': 'https://openalex.org/C111919701', 'wikidata': 'https://www.wikidata.org/wiki/Q9135', 'display_name': 'Operating system', 'level': 1, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D003199', 'descriptor_name': 'Computer Systems', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D005583', 'descriptor_name': 'Fourier Analysis', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D006358', 'descriptor_name': 'Hot Temperature', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D013678', 'descriptor_name': 'Technology, Pharmaceutical', 'qualifier_ui': 'Q000379', 'qualifier_name': 'methods', 'is_major_topic': True}, {'descriptor_ui': 'D004345', 'descriptor_name': 'Drug Industry', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004345', 'descriptor_name': 'Drug Industry', 'qualifier_ui': 'Q000379', 'qualifier_name': 'methods', 'is_major_topic': False}, {'descriptor_ui': 'D005615', 'descriptor_name': 'Freezing', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D019265', 'descriptor_name': 'Spectroscopy, Near-Infrared', 'qualifier_ui': 'Q000379', 'qualifier_name': 'methods', 'is_major_topic': False}, {'descriptor_ui': 'D019265', 'descriptor_name': 'Spectroscopy, Near-Infrared', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013678', 'descriptor_name': 'Technology, Pharmaceutical', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 4, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.1208/s12249-018-1091-3', 'pdf_url': 'https://link.springer.com/content/pdf/10.1208/s12249-018-1091-3.pdf', 'source': {'id': 'https://openalex.org/S1234972', 'display_name': 'AAPS PharmSciTech', 'issn_l': '1530-9932', 'issn': ['1530-9932'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310319900', 'host_organization_name': 'Springer Science+Business Media', 'host_organization_lineage': ['https://openalex.org/P4310319965', 'https://openalex.org/P4310319900'], 'host_organization_lineage_names': ['Springer Nature', 'Springer Science+Business Media'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://europepmc.org/articles/pmc6283664', 'pdf_url': 'https://europepmc.org/articles/pmc6283664?pdf=render', 'source': {'id': 'https://openalex.org/S4306400806', 'display_name': 'Europe PMC (PubMed Central)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1303153112', 'host_organization_name': 'European Bioinformatics Institute', 'host_organization_lineage': ['https://openalex.org/I1303153112'], 'host_organization_lineage_names': ['European Bioinformatics Institute'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'acceptedVersion', 'is_accepted': True, 'is_published': False}, {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6283664', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'acceptedVersion', 'is_accepted': True, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/29948985', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1208/s12249-018-1091-3', 'pdf_url': 'https://link.springer.com/content/pdf/10.1208/s12249-018-1091-3.pdf', 'source': {'id': 'https://openalex.org/S1234972', 'display_name': 'AAPS PharmSciTech', 'issn_l': '1530-9932', 'issn': ['1530-9932'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310319900', 'host_organization_name': 'Springer Science+Business Media', 'host_organization_lineage': ['https://openalex.org/P4310319965', 'https://openalex.org/P4310319900'], 'host_organization_lineage_names': ['Springer Nature', 'Springer Science+Business Media'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [{'score': 0.57, 'id': 'https://metadata.un.org/sdg/9', 'display_name': 'Industry, innovation and infrastructure'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 8, 'referenced_works': ['https://openalex.org/W1542860649', 'https://openalex.org/W1770883461', 'https://openalex.org/W1978145063', 'https://openalex.org/W1989195393', 'https://openalex.org/W2012358846', 'https://openalex.org/W2128728535', 'https://openalex.org/W2158863190', 'https://openalex.org/W2766983743'], 'related_works': ['https://openalex.org/W839656262', 'https://openalex.org/W3217336248', 'https://openalex.org/W2983486423', 'https://openalex.org/W2807736360', 'https://openalex.org/W2465558286', 'https://openalex.org/W2261411557', 'https://openalex.org/W2083259132', 'https://openalex.org/W2032947319', 'https://openalex.org/W2018365323', 'https://openalex.org/W1585744361'], 'abstract_inverted_index': {'Continuous': [0], 'manufacturing,': [1], 'a': [2, 54, 59], 'gaining': [3], 'interest': [4], 'paradigm': [5], 'in': [6, 32], 'the': [7, 24], 'pharmaceutical': [8, 67], 'industry,': [9], 'requires': [10], 'in-process': [11], 'monitoring': [12], 'of': [13, 26], 'critical': [14], 'process': [15, 42, 61], 'parameters': [16], 'to': [17, 64], 'ensure': [18], 'product': [19], 'consistency.': [20], 'This': [21], 'study': [22], 'demonstrated': [23], 'application': [25], 'Fourier': [27], 'transform': [28], 'near-infrared': [29], '(FT-NIR)': [30], 'spectroscopy': [31], 'conjunction': [33], 'with': [34, 53], 'chemometrics': [35], 'modeling': [36], 'for': [37], 'in-line': [38], 'hot': [39], 'melt': [40], 'extrusion': [41], 'monitoring.': [43], 'The': [44], 'obtained': [45], 'results': [46], 'suggested': [47], 'that': [48], 'inline': [49], 'FT-NIR': [50], 'analysis,': [51], 'along': [52], 'tailored': [55], 'NIR': [56], 'reflector,': [57], 'is': [58], 'viable': [60], 'analytical': [62], 'tool': [63], 'monitor': [65], 'active': [66], 'ingredient': [68], 'concentration': [69], 'as': [70, 72], 'well': [71], 'processing': [73], 'parameters.': [74]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2807736360', 'counts_by_year': [{'year': 2024, 'cited_by_count': 5}, {'year': 2023, 'cited_by_count': 1}, {'year': 2022, 'cited_by_count': 2}, {'year': 2021, 'cited_by_count': 5}, {'year': 2020, 'cited_by_count': 7}, {'year': 2019, 'cited_by_count': 8}, {'year': 2018, 'cited_by_count': 1}], 'updated_date': '2024-09-19T02:32:38.155390', 'created_date': '2018-06-21'}