Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2807566785', 'doi': 'https://doi.org/10.1007/s12033-018-0067-6', 'title': 'Pellino-1 Protects Periodontal Ligament Stem Cells Against H2O2-Induced Apoptosis via Activation of NF-κB Signaling', 'display_name': 'Pellino-1 Protects Periodontal Ligament Stem Cells Against H2O2-Induced Apoptosis via Activation of NF-κB Signaling', 'publication_year': 2018, 'publication_date': '2018-06-02', 'ids': {'openalex': 'https://openalex.org/W2807566785', 'doi': 'https://doi.org/10.1007/s12033-018-0067-6', 'mag': '2807566785', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/29860626'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1007/s12033-018-0067-6', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S31191957', 'display_name': 'Molecular Biotechnology', 'issn_l': '1073-6085', 'issn': ['1073-6085', '1559-0305'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310319900', 'host_organization_name': 'Springer Science+Business Media', 'host_organization_lineage': ['https://openalex.org/P4310319965', 'https://openalex.org/P4310319900'], 'host_organization_lineage_names': ['Springer Nature', 'Springer Science+Business Media'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5108987083', 'display_name': 'Jiangang Tian', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I87445476', 'display_name': "Xi'an Jiaotong University", 'ror': 'https://ror.org/017zhmm22', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I87445476']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Jiangang Tian', 'raw_affiliation_strings': ["Key Laboratory of Shaanxi Province for Craniofacial Precision Medicine Research, College of Stomatology, Xi'an Jiaotong University, Xi'an, 710004, Shaanxi Province, China"], 'affiliations': [{'raw_affiliation_string': "Key Laboratory of Shaanxi Province for Craniofacial Precision Medicine Research, College of Stomatology, Xi'an Jiaotong University, Xi'an, 710004, Shaanxi Province, China", 'institution_ids': ['https://openalex.org/I87445476']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5113066397', 'display_name': 'Liufang Gu', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210131893', 'display_name': "Second Affiliated Hospital of Xi'an Jiaotong University", 'ror': 'https://ror.org/03aq7kf18', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210131893']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Liufang Gu', 'raw_affiliation_strings': ["Department of Hematology, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, 710004, Shaanxi Province, China"], 'affiliations': [{'raw_affiliation_string': "Department of Hematology, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, 710004, Shaanxi Province, China", 'institution_ids': ['https://openalex.org/I4210131893']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5082293572', 'display_name': 'Andrew Adams', 'orcid': 'https://orcid.org/0000-0001-8925-9956'}, 'institutions': [{'id': 'https://openalex.org/I202697423', 'display_name': 'University of Zurich', 'ror': 'https://ror.org/02crff812', 'country_code': 'CH', 'type': 'education', 'lineage': ['https://openalex.org/I202697423']}], 'countries': ['CH'], 'is_corresponding': False, 'raw_author_name': 'Andrew Adams', 'raw_affiliation_strings': ['Institute of Veterinary Physiology, University of Zurich, 8057, Zurich, Switzerland'], 'affiliations': [{'raw_affiliation_string': 'Institute of Veterinary Physiology, University of Zurich, 8057, Zurich, Switzerland', 'institution_ids': ['https://openalex.org/I202697423']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5100676194', 'display_name': 'Xueliang Wang', 'orcid': 'https://orcid.org/0000-0003-2834-9370'}, 'institutions': [{'id': 'https://openalex.org/I87445476', 'display_name': "Xi'an Jiaotong University", 'ror': 'https://ror.org/017zhmm22', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I87445476']}], 'countries': ['CN'], 'is_corresponding': True, 'raw_author_name': 'Xueliang Wang', 'raw_affiliation_strings': ["Department of Epidemiology and Biostatistics, School of Public Health, Xi'an Jiaotong University Health Science Center, Xi'an, 710061, Shaanxi Province, China"], 'affiliations': [{'raw_affiliation_string': "Department of Epidemiology and Biostatistics, School of Public Health, Xi'an Jiaotong University Health Science Center, Xi'an, 710061, Shaanxi Province, China", 'institution_ids': ['https://openalex.org/I87445476']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5108823342', 'display_name': 'Ruizhe Huang', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I87445476', 'display_name': "Xi'an Jiaotong University", 'ror': 'https://ror.org/017zhmm22', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I87445476']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Ruizhe Huang', 'raw_affiliation_strings': ["Key Laboratory of Shaanxi Province for Craniofacial Precision Medicine Research, College of Stomatology, Xi'an Jiaotong University, Xi'an, 710004, Shaanxi Province, China"], 'affiliations': [{'raw_affiliation_string': "Key Laboratory of Shaanxi Province for Craniofacial Precision Medicine Research, College of Stomatology, Xi'an Jiaotong University, Xi'an, 710004, Shaanxi Province, China", 'institution_ids': ['https://openalex.org/I87445476']}]}], 'institution_assertions': [], 'countries_distinct_count': 2, 'institutions_distinct_count': 3, 'corresponding_author_ids': ['https://openalex.org/A5100676194'], 'corresponding_institution_ids': ['https://openalex.org/I87445476'], 'apc_list': None, 'apc_paid': None, 'fwci': 0.263, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 8, 'citation_normalized_percentile': {'value': 0.658768, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 83, 'max': 84}, 'biblio': {'volume': '60', 'issue': '8', 'first_page': '533', 'last_page': '538'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T11884', 'display_name': 'Redox biology and oxidative stress', 'score': 0.9972, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T11884', 'display_name': 'Redox biology and oxidative stress', 'score': 0.9972, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T11480', 'display_name': 'Connexins and lens biology', 'score': 0.9887, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10371', 'display_name': 'Immune Response and Inflammation', 'score': 0.968, 'subfield': {'id': 'https://openalex.org/subfields/2403', 'display_name': 'Immunology'}, 'field': {'id': 'https://openalex.org/fields/24', 'display_name': 'Immunology and Microbiology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [], 'concepts': [{'id': 'https://openalex.org/C2779886569', 'wikidata': 'https://www.wikidata.org/wiki/Q7168661', 'display_name': 'Periodontal ligament stem cells', 'level': 4, 'score': 0.8566963}, {'id': 'https://openalex.org/C190283241', 'wikidata': 'https://www.wikidata.org/wiki/Q14599311', 'display_name': 'Apoptosis', 'level': 2, 'score': 0.6492223}, {'id': 'https://openalex.org/C2775838275', 'wikidata': 'https://www.wikidata.org/wiki/Q410776', 'display_name': 'Superoxide dismutase', 'level': 3, 'score': 0.6333885}, {'id': 'https://openalex.org/C127561419', 'wikidata': 'https://www.wikidata.org/wiki/Q224527', 'display_name': 'Downregulation and upregulation', 'level': 3, 'score': 0.5909364}, {'id': 'https://openalex.org/C2778979269', 'wikidata': 'https://www.wikidata.org/wiki/Q106951292', 'display_name': 'Catalase', 'level': 3, 'score': 0.57576203}, {'id': 'https://openalex.org/C95444343', 'wikidata': 'https://www.wikidata.org/wiki/Q7141', 'display_name': 'Cell biology', 'level': 1, 'score': 0.5695866}, {'id': 'https://openalex.org/C28328180', 'wikidata': 'https://www.wikidata.org/wiki/Q48196', 'display_name': 'Stem cell', 'level': 2, 'score': 0.48234552}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.47175178}, {'id': 'https://openalex.org/C62478195', 'wikidata': 'https://www.wikidata.org/wiki/Q828130', 'display_name': 'Signal transduction', 'level': 2, 'score': 0.46027777}, {'id': 'https://openalex.org/C2776151105', 'wikidata': 'https://www.wikidata.org/wiki/Q898814', 'display_name': 'Oxidative stress', 'level': 2, 'score': 0.44795337}, {'id': 'https://openalex.org/C2778760513', 'wikidata': 'https://www.wikidata.org/wiki/Q24773045', 'display_name': 'Glutathione peroxidase', 'level': 4, 'score': 0.4359184}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.3424764}, {'id': 'https://openalex.org/C153911025', 'wikidata': 'https://www.wikidata.org/wiki/Q7202', 'display_name': 'Molecular biology', 'level': 1, 'score': 0.32969558}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.2115078}, {'id': 'https://openalex.org/C181199279', 'wikidata': 'https://www.wikidata.org/wiki/Q8047', 'display_name': 'Enzyme', 'level': 2, 'score': 0.1274072}, {'id': 'https://openalex.org/C160160445', 'wikidata': 'https://www.wikidata.org/wiki/Q24769688', 'display_name': 'Alkaline phosphatase', 'level': 3, 'score': 0.05167955}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.05141005}], 'mesh': [{'descriptor_ui': 'D017209', 'descriptor_name': 'Apoptosis', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': True}, {'descriptor_ui': 'D006861', 'descriptor_name': 'Hydrogen Peroxide', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': True}, {'descriptor_ui': 'D016328', 'descriptor_name': 'NF-kappa B', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D009687', 'descriptor_name': 'Nuclear Proteins', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D010513', 'descriptor_name': 'Periodontal Ligament', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D015398', 'descriptor_name': 'Signal Transduction', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': True}, {'descriptor_ui': 'D013234', 'descriptor_name': 'Stem Cells', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D044767', 'descriptor_name': 'Ubiquitin-Protein Ligases', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D000975', 'descriptor_name': 'Antioxidants', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000975', 'descriptor_name': 'Antioxidants', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D017209', 'descriptor_name': 'Apoptosis', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002374', 'descriptor_name': 'Catalase', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002374', 'descriptor_name': 'Catalase', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D002470', 'descriptor_name': 'Cell Survival', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002470', 'descriptor_name': 'Cell Survival', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': False}, {'descriptor_ui': 'D015536', 'descriptor_name': 'Down-Regulation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015536', 'descriptor_name': 'Down-Regulation', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006861', 'descriptor_name': 'Hydrogen Peroxide', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D016328', 'descriptor_name': 'NF-kappa B', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009687', 'descriptor_name': 'Nuclear Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D018384', 'descriptor_name': 'Oxidative Stress', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': False}, {'descriptor_ui': 'D018384', 'descriptor_name': 'Oxidative Stress', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D010513', 'descriptor_name': 'Periodontal Ligament', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D017382', 'descriptor_name': 'Reactive Oxygen Species', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D017382', 'descriptor_name': 'Reactive Oxygen Species', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015398', 'descriptor_name': 'Signal Transduction', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013234', 'descriptor_name': 'Stem Cells', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013482', 'descriptor_name': 'Superoxide Dismutase', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D013482', 'descriptor_name': 'Superoxide Dismutase', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D044767', 'descriptor_name': 'Ubiquitin-Protein Ligases', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015854', 'descriptor_name': 'Up-Regulation', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': False}, {'descriptor_ui': 'D015854', 'descriptor_name': 'Up-Regulation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1007/s12033-018-0067-6', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S31191957', 'display_name': 'Molecular Biotechnology', 'issn_l': '1073-6085', 'issn': ['1073-6085', '1559-0305'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310319900', 'host_organization_name': 'Springer Science+Business Media', 'host_organization_lineage': ['https://openalex.org/P4310319965', 'https://openalex.org/P4310319900'], 'host_organization_lineage_names': ['Springer Nature', 'Springer Science+Business Media'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/29860626', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'id': 'https://metadata.un.org/sdg/2', 'display_name': 'Zero hunger', 'score': 0.52}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 15, 'referenced_works': ['https://openalex.org/W1551392207', 'https://openalex.org/W1992517860', 'https://openalex.org/W1995468432', 'https://openalex.org/W1995909916', 'https://openalex.org/W1999334284', 'https://openalex.org/W2000121863', 'https://openalex.org/W2025552012', 'https://openalex.org/W2035189746', 'https://openalex.org/W2046412303', 'https://openalex.org/W2068299688', 'https://openalex.org/W2071103462', 'https://openalex.org/W2095690145', 'https://openalex.org/W2143237736', 'https://openalex.org/W2159284467', 'https://openalex.org/W2182804823'], 'related_works': ['https://openalex.org/W4313039917', 'https://openalex.org/W3214998341', 'https://openalex.org/W3171294832', 'https://openalex.org/W3024950597', 'https://openalex.org/W2593871493', 'https://openalex.org/W2213996271', 'https://openalex.org/W2186775341', 'https://openalex.org/W2105259559', 'https://openalex.org/W2062622163', 'https://openalex.org/W1828599895'], 'abstract_inverted_index': None, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2807566785', 'counts_by_year': [{'year': 2024, 'cited_by_count': 1}, {'year': 2023, 'cited_by_count': 2}, {'year': 2022, 'cited_by_count': 2}, {'year': 2021, 'cited_by_count': 1}, {'year': 2020, 'cited_by_count': 2}], 'updated_date': '2024-12-10T09:42:23.311787', 'created_date': '2018-06-13'}