Publication Information

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1377, 1388, 1414, 1460, 1484, 1658], 'infusion': [80, 189, 1079, 1097, 1172, 1596], 'has': [81, 190, 1000, 1262], 'GLP-1-dependent': [82, 191], 'and': [83, 192, 251, 276, 375, 383, 432, 522, 526, 1019, 1026, 1056, 1083, 1113, 1146, 1176, 1234, 1265, 1275, 1392, 1451, 1487, 1604, 1668, 1677, 1691], '-independent': [84, 193], 'actions': [85, 194, 1482, 1506], 'opposing': [87, 196], 'tolerance,': [91, 200, 651], 'resulting': [92, 201, 1369], 'an': [94, 203, 223, 464, 1101, 1371], 'overall': [95, 204, 1287, 1372], 'improvement': [96, 103, 205, 212, 1252], 'healthy': [98, 207, 456, 1244, 1312], 'male': [99, 105, 208, 214, 1060], 'volunteers': [100, 209, 1313], 'but': [101, 210, 997, 1314], 'no': [102, 211, 1250], 'patients': [106, 215, 1215, 1317], 'diabetes.': [108, 217, 1322], 'Reduction': [218], 'post-prandial': [220, 233, 350], 'hyperglycemia': [221, 234], 'is': [222, 676, 958, 968, 1074, 1115, 1193, 1296, 1306, 1353, 1399, 1432, 1507, 1559], 'important': [224, 1477], 'goal': [225], 'diabetes': [227, 266, 395, 1220, 1338, 1690], 'treatment.': [228], 'Two': [229], 'key': [230], 'variables': [231], 'controlling': [232], 'are': [235, 261, 860, 1108, 1475, 1683], 'emptying,': [237, 271, 635, 939, 1663], 'which': [238, 780, 1422], 'determines': [239], 'rate': [240, 1082], 'delivery': [242], 'nutrients': [244, 495], 'to': [245, 455, 463, 529, 632, 794, 849, 969, 1006, 1148, 1188, 1195, 1214, 1276, 1307, 1350, 1401, 1407, 1456, 1538, 1620, 1622, 1631, 1694], 'absorptive': [246], 'areas': [247], 'the': [249, 252, 343, 361, 447, 482, 523, 551, 557, 624, 639, 643, 647, 654, 787, 798, 830, 844, 850, 856, 934, 963, 1077, 1088, 1094, 1122, 1164, 1167, 1286, 1303, 1343, 1357, 1363, 1379, 1396, 1444, 1480, 1500, 1508, 1539, 1678], 'gut,': [250], 'effectiveness': [253], 'insulin.': [255], 'Glucagon-like': [256], 'analogs': [260], 'highly': [262], 'successful': [263], 'therapies': [264], 'for': [265, 715, 1205, 1409, 1443], 'because': [267, 662, 962], 'they': [268, 636], 'decrease': [269, 474, 668, 936, 1277], 'increase': [272, 1102], 'glucose-stimulated': [273], 'insulin': [274, 389, 422, 476, 487, 670, 947, 971, 981, 995, 1177, 1235, 1278, 1352, 1367, 1670, 1681], 'secretion,': [275, 671, 948, 996, 1368], 'suppress': [277], 'food': [278], 'intake.': [279], 'investigate': [342, 854], 'effect': [344, 648, 655, 965, 977, 1288, 1305, 1510], 'administration': [348], 'excursion': [352, 1236], 'man': [354, 984, 1261, 1563], '(see': [355], 'Figure': [356], '1).': [357], 'Previous': [358], 'work': [359], 'from': [360, 371, 376, 429, 446], 'same': [362], 'group': [363], 'had': [364, 807], 'shown': [365], 'stimulates': [368], 'GLP-1': [369, 835, 924, 955, 967, 991, 1014, 1050, 1512, 1545], 'secretion': [370, 390, 423, 428, 982, 1055, 1178, 1682], 'mouse': [372], 'enteroendocrine': [373], 'cells': [374, 380, 431], 'human': [377], 'pancreatic': [378], 'alpha': [379, 433], 'vitro': [382], 'enhanced': [388], 'animal': [392], 'models': [393], '(Ellingsgaard': [396], '2011Ellingsgaard': [399], 'Hauselmann': [401], 'I.': [402], 'Schuler': [403], 'B.': [404], 'Habib': [405], 'A.M.': [406], 'Baggio': [407], 'L.L.': [408], 'Meier': [409], 'D.T.': [410], 'Eppler': [411], 'E.': [412], 'Bouzakri': [413], 'Wueest': [415], 'S.': [416, 1141, 1521], 'Muller': [417], 'Y.D.': [418], 'al.Interleukin-6': [420], 'enhances': [421], 'by': [424, 491, 549, 679, 784, 840, 862, 952, 1013, 1426, 1544], 'increasing': [425], 'peptide-1': [427, 1593], 'L': [430], 'cells.Nat.': [434], 'Med.': [435], '2011;': [436], '17:': [437], '1481-1489Crossref': [438], '(599)': [441], 'Scholar).': [443, 709, 1069, 1615], 'As': [444], 'predicted': [445], 'rodent': [448], 'work,': [449], 'when': [450, 1087], 'recombinant': [451], 'was': [453, 459, 470, 781, 950, 1090, 1098, 1256], 'given': [454, 1213], 'volunteers,': [457], 'there': [458, 1114, 1474], 'improved': [460], 'orally': [465], 'ingested': [466, 554], 'meal.': [467, 851], 'However,': [468], 'associated': [471, 1020, 1099], 'a': [473, 530, 616, 698, 775, 923, 941, 959, 1007, 1224, 1228, 1238], 'Improved': [478], 'presence': [483], 'reduced': [485, 633, 1679], 'circulating': [486, 834, 1104], 'can': [488, 992, 1120, 1144, 1493], 'be': [489, 1186, 1203, 1424, 1441, 1454, 1494, 1623], 'explained': [490], 'slower': [492], 'absorption': [493], '(Gentilcore': [496], '2006Gentilcore': [499], 'D.': [500, 1044, 1046, 1527, 1531], 'Chaikomin': [501], 'R.': [502, 1529], 'Jones': [503], 'K.L.': [504], 'Russo': [505], 'A.': [506, 1586, 1588], 'Feinle-Bisset': [507], 'C.': [508, 687], 'Wishart': [509], 'J.M.': [510], 'Rayner': [511], 'C.K.': [512], 'Horowitz': [513], 'M.': [514], 'Effects': [515, 1641], 'fat': [517], 'glycemic,': [524], 'insulin,': [525], 'incretin': [527], 'responses': [528], 'carbohydrate': [531], 'meal': [532, 640, 845, 1089], 'type': [534, 1218, 1320, 1448, 1688], '2': [535, 1219, 1321, 1449, 1689], 'diabetes.J.': [536], 'Clin.': [537], 'Endocrinol.': [538], '2006;': [540], '91:': [541], '2062-2067Crossref': [542], '(240)': [545], 'Scholar);': [547], 'here,': [548], 'measuring': [550], 'appearance': [552], 'paracetamol': [555], 'circulation,': [558], 'demonstrated': [615, 774, 1003], 'reduction': [617, 945, 1229], 'emptying.': [620, 666, 828], 'To': [621, 852], 'see': [622, 1457], 'whether': [623, 855, 1197, 1437, 1458], 'were': [629, 837], 'indeed': [630], 'secondary': [631], 'next': [637], 'infused': [638, 1010, 1091], 'directly': [641, 1092, 1124], 'into': [642, 1093], 'duodenum.': [644], 'This': [645, 957, 973, 1298], 'abrogated': [646, 951], 'indicating': [652], 'occurs': [661], 'delayed': [664], 'The': [667, 944, 1207, 1469, 1672], 'however,': [672, 949, 1434], 'persisted.': [673], 'Circulating': [674], 'moderately': [677], 'elevated': [678, 1657], 'exercise': [680], '(Muñoz-Cánoves': [681], '2013Muñoz-Cánoves': [684], 'P.': [685, 1129], 'Scheele': [686], 'Serrano': [690], 'A.L.': [691], 'myokine': [693], 'signaling': [694], 'skeletal': [696], 'muscle:': [697], 'double-edged': [699], 'sword?.FEBS': [700], 'J.': [701, 1523, 1581], '2013;': [702, 1608], '280:': [703], '4131-4148Crossref': [704], '(432)': [707], 'endurance': [711], 'athletes': [712], 'who': [713], 'ran': [714], '60': [716], 'min,': [717], 'modest': [776], 'rise': [777], 'IL-6,': [779, 801], 'dramatically': [782], 'increased': [783, 839, 1080, 1601], 'blockade': [785, 953, 1415], 'receptor': [789, 806, 925, 1546], 'tocilizumab,': [791], 'presumably': [792], 'due': [793], 'decreased': [795], 'clearance.': [796], 'Despite': [797], 'elevation': [799, 821, 1335, 1389], 'runners': [802], 'whom': [804], 'been': [808, 1002], 'blocked': [809], 'exhibited': [810], 'much': [811], 'faster': [812], 'than': [815], 'without': [816], 'blockade,': [817], 'suggesting': [818, 940], 'exercise-induced': [820], 'does': [824], 'physiologically': [825], 'slow': [826, 1272], 'present': [831, 1208, 1470], 'study,': [832], 'peripheral': [833], 'levels': [836], 'not': [838, 932, 1315, 1560], 'either': [842], 'before': [843], 'or': [846], 'response': [848, 1005], 'further': [853], 'mediated': [861, 1012], 'GLP-1,': [863], 'used': [920, 1442], 'exendin': [921, 929], '9-39,': [922], 'antagonist.': [926], 'Addition': [927], '9-39': [930], 'did': [931, 1242], 'reverse': [933], 'IL-6-induced': [935], 'GLP-1-independent': [942], 'pathway.': [943], 'receptors.': [956], 'surprising': [960], 'finding': [961], 'canonical': [964], 'stimulate': [970, 1121], 'intriguing': [974], 'GLP-1-mediated': [975, 1364], 'inhibitory': [976], 'remains': [985], 'unexplained.': [986], 'Recent': [987], 'evidence': [988, 1117, 1301, 1398], 'suggests': [989], 'paradoxically': [993], 'inhibit': [994], 'phenomenon': [999], 'only': [1001], 'high': [1008], 'dose': [1009], 'centrally,': [1011], 'receptors': [1015, 1051], 'hindbrain': [1017], 'neurons,': [1018], 'sympathetic': [1022], 'nervous': [1023, 1048], 'system': [1024, 1049], '(SNS)': [1025], 'hypothalamo-pituitary-adrenal': [1027], 'axis': [1028], 'activation': [1029], '(Jessen': [1030], '2017Jessen': [1033], 'Smith': [1035], 'E.P.': [1036], 'Ulrich-Lai': [1037], 'Y.': [1038], 'Herman': [1039], 'J.P.': [1040], 'Seeley': [1041], 'R.J.': [1042], 'Sandoval': [1043], 'D’Alessio': [1045], 'Central': [1047], 'regulate': [1052], 'islet': [1053], 'hormone': [1054, 1505], 'homeostasis': [1058], 'rats.Endocrinology.': [1061], '2017;': [1062], '158:': [1063], '2124-2133Crossref': [1064], '(25)': [1067], 'conjunction,': [1072], 'it': [1073, 1241, 1452], 'noteworthy': [1075], 'heart': [1081], 'triggered': [1084], 'shivering;': [1085], 'furthermore,': [1086], 'duodenum,': [1095], 'glucagon.': [1105], 'These': [1106], 'reminiscent': [1109], 'SNS': [1111, 1123, 1181], 'stimulation,': [1112], 'some': [1116], '(März': [1125], '1998März': [1128], 'Cheng': [1130], 'J.G.': [1131], 'Gadient': [1132], 'R.A.': [1133], 'Patterson': [1134], 'P.H.': [1135], 'Stoyan': [1136], 'T.': [1137], 'Otten': [1138], 'U.': [1139], 'Rose-John': [1140], 'Sympathetic': [1142], 'neurons': [1143], 'produce': [1145], 'respond': [1147], 'interleukin': [1149], '6.Proc.': [1150], 'Natl.': [1151], 'Acad.': [1152], 'Sci.': [1153], 'USA.': [1154], '1998;': [1155], '95:': [1156], '3251-3256Crossref': [1157], '(283)': [1160], 'Scholar),': [1162], 'posing': [1163], 'question:': [1165], 'do': [1166], 'acute': [1170, 1333], 'occur': [1179], 'stimulation?': [1182], 'Future': [1183], 'studies': [1184, 1628], 'will': [1185, 1356, 1405, 1453], 'required': [1187], 'address': [1189], 'question.': [1191], 'It': [1192, 1431], 'natural': [1194], 'ask': [1196], 'these': [1198, 1248], 'might': [1202, 1423, 1462], 'exploited': [1204], 'therapy.': [1206], 'study': [1209, 1299, 1471], 'shows': [1210, 1472], 'mild': [1217, 1319], '(well': [1221], 'controlled': [1222], 'single': [1225], 'agent)': [1226], 'caused': [1227], 'both': [1231], 'following': [1237], 'meal,': [1239], 'as': [1240, 1419], 'volunteers.': [1245], 'Importantly,': [1246], 'patients,': [1249], 'significant': [1251], 'seen.': [1257], 'If': [1258], 'two': [1263], 'distinct': [1264], 'opposed': [1266], '(to': [1271], 'secretion),': [1279], 'understanding': [1280], 'their': [1281], 'relative': [1282], 'contribution': [1283], 'and,': [1284], 'therefore,': [1285, 1617], 'different': [1293], 'clinical': [1294], 'scenarios': [1295], 'paramount.': [1297], 'provides': [1300], 'summative': [1304], 'improve': [1308], 'Does': [1323], 'trend': [1325], 'continue': [1326, 1621], 'more': [1328, 1464], 'severe': [1329, 1337, 1383], 'diabetes—that': [1330], 'is,': [1331], 'would': [1332], 'worsen': [1339], 'tolerance?': [1341], 'On': [1342], 'other': [1344], 'hand,': [1345], 'where': [1346], 'β': [1347], 'cell': [1348, 1699], 'ability': [1349], 'secrete': [1351], 'severely': [1354], 'compromised,': [1355], 'outweigh': [1362], 'inhibition': [1365], 'clinically': [1373], 'favorable': [1374, 1465], 'effect?': [1375], 'Could': [1376], 'exacerbate': [1378, 1390], 'gastroparesis': [1380], 'seen': [1381], 'diabetes?': [1384], 'Finally,': [1385], 'could': [1386, 1440], 'chronic': [1387, 1459], 'inflammation': [1391], 'atherosclerosis?': [1393], 'summary,': [1395], 'current': [1397], 'enough': [1400], 'suggest': [1402], 'we': [1404], 'need': [1406], 'look': [1408], 'deleterious': [1410], 'metabolic': [1411, 1481, 1491, 1504, 1627], 'consequences': [1412], 'diseases': [1417], 'such': [1418], 'rheumatoid': [1420], 'arthritis,': [1421], 'exacerbated': [1425], 'concurrent': [1427], 'treatment': [1428, 1446, 1461], 'glucocorticoids.': [1430], 'not,': [1433], 'presently': [1435], 'obvious': [1436], 'IL-6-based': [1438], 'therapy': [1439], 'future': [1445], 'diabetes,': [1450], 'interesting': [1455], 'have': [1463], 'metabolism.': [1468], 'clearly': [1476], 'differences': [1478], 'between': [1479], 'mice': [1486], 'man,': [1488], 'underlining': [1489], 'control': [1492, 1540], 'species': [1495, 1501], 'specific;': [1496], 'another': [1497], 'example': [1498], 'specificity': [1502], 'thermogenic': [1509], 'rodents': [1514, 1630], '(Heppner': [1515], '2015Heppner': [1518], 'K.M.': [1519], 'Marks': [1520], 'Holland': [1522], 'Ottaway': [1524], 'N.': [1525], 'Smiley': [1526], 'Dimarchi': [1528], 'Perez-Tilve': [1530], 'Contribution': [1532], 'brown': [1534], 'adipose': [1535], 'tissue': [1536], 'activity': [1537], 'energy': [1542, 1602], 'balance': [1543], 'signalling': [1547], 'mice.Diabetologia.': [1549], '2015;': [1550], '58:': [1551], '2124-2132Crossref': [1552], '(35)': [1555], 'Scholar)': [1557], 'apparent': [1561], '(Tan': [1564], '2013Tan': [1567], 'T.M.': [1568], 'Field': [1569], 'B.C.T.': [1570], 'McCullough': [1571], 'K.A.': [1572], 'Troke': [1573], 'R.C.': [1574], 'Chambers': [1575], 'E.S.': [1576], 'Salem': [1577], 'V.': [1578], 'Gonzalez': [1579], 'Maffe': [1580], 'Baynes': [1582], 'K.C.R.': [1583], 'De': [1584], 'Silva': [1585], 'Viardot': [1587], 'al.Coadministration': [1590], 'during': [1594], 'glucagon': [1595], 'results': [1599], 'expenditure': [1603], 'amelioration': [1605], 'hyperglycemia.Diabetes.': [1607], '62:': [1609], '1131-1138Crossref': [1610], '(158)': [1613], 'It,': [1616], 'behooves': [1618], 'us': [1619], 'wary': [1624], 'extrapolating': [1626], 'humans.': [1632], 'Delays': [1634], 'Gastric': [1635], 'Emptying': [1636], 'Humans': [1638], 'Direct': [1640], 'Glycemic': [1643], 'ControlLang': [1644], 'al.Cell': [1647], 'MetabolismMay': [1648], '3,': [1649], '2018In': [1650], 'BriefLehrskov': [1651], 'al.': [1653], 'show': [1654], 'acutely': [1656], 'reduces': [1664, 1669], 'postprandial': [1665], 'blood': [1666], 'glucose,': [1667], 'delay': [1673], 'meal-stimulated': [1680], 'maintained': [1684], 'individuals': [1686], 'may': [1692], 'contribute': [1693], 'long-term': [1695], 'preservation': [1696], 'beta': [1698], 'function.': [1700], 'Full-Text': [1701], 'Open': [1703], 'Archive': [1704]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2806508209', 'counts_by_year': [{'year': 2021, 'cited_by_count': 1}, {'year': 2020, 'cited_by_count': 2}, {'year': 2018, 'cited_by_count': 1}], 'updated_date': '2024-12-08T21:17:15.390557', 'created_date': '2018-06-13'}