Abstract: Aims & Objectives: To examine if use of honey is not inferior to standard treatment in terms of time to wound healing in critically ill children with pressure ulcers. Methods We randomly assigned children <17 years of age with stage I to III pressure ulcer in the intensive care unit to ‘honey dressing’ or ‘standard treatment’ groups; medicated honey dressing or standard dressing was applied in the two groups, respectively. Children with ulcers > 5 cm diameter and those with active infection were excluded. The respective dressing was changed when soiled, for a maximum period of 8 weeks or till healthy granulation tissue appeared. Major outcomes were time to wound healing and proportion with complete wound healing. Enrolled patients were followed-up till death or discharge from the hospital. Data were analysed using STATA 13. Results In this ongoing trial, we have enrolled 33 children - 18 and 15 in ‘honey dressing’ and ‘standard treatment’ groups, respectively. Baseline characteristics including nutritional status were comparable between the groups. The time to wound healing was shorter (median [IQR]: 7 [3, 14] vs. 9 [5, 19] days; p=0.30) and a higher proportion of children achieved wound healing in the ‘honey dressing’ group (83% vs. 71%; p=0.41) but the differences were not significant. Conclusions Use of honey dressing seems to decrease the time to wound healing. These preliminary findings need to be confirmed upon enrolment of the required sample size.