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'this.After': [588], 'completing': [589], 'Tübingen,': [593], 'record': [595], 'implies': [596], 'turned': [600], 'clinic': [604], 'biology.': [606, 650, 1887], 'He': [607, 1547, 1623], 'pursued': [610], 'evolving': [612], 'interest': [615], 'but,': [618], 'whatever': [620], 'reason,': [621], 'sights': [625], 'America.': [627], 'Van': [628], 'Potter,': [629, 664], 'University': [632, 1756], 'Wisconsin,': [634, 1758], 'gaining': [636], 'prominence': [637], 'trying': [639], 'connect': [641], 'cancer': [642, 675], 'what': [644], 'would': [646, 1864], 'called': [648], 'Following': [651], 'successful': [653], 'PhD': [654], '(1967),': [656], 'likely': [660, 793], 'top': [661], 'recommendation': [662], 'held': [665], 'high': [667, 1086], 'esteem': [668], 'U.S.': [671], 'research': [676], 'guild,': [677], 'post': [681], 'George': [683, 753, 1790], "Palade's": [684], 'group': [685, 797], 'University.At': [688], 'University,': [690], 'two': [691, 1041], '“schools”': [692], '1940s,': [699], 'focused': [701], 'looking': [703], 'another,': [711], 'daring,': [713], 'enterprise': [714], 'oriented': [717], 'homogenates': [719], 'assessing': [721], 'biochemical': [723], 'reactions': [724], 'captured': [728], 'them': [730, 1549, 1579], '(Pederson,': [731], '2013).': [732], 'regards': [735], 'dawning': [737], 'protein': [740, 1231, 1249, 1365, 1401], 'traffic': [741], 'concept,': [742], 'point': [745], 'made': [748, 1646], 'epistemology': [750], 'Palade': [754, 770, 796, 816, 1070], 'become': [756], 'fascinated': [757], 'based': [761], 'own': [764], 'work': [765], 'before': [766, 1854], 'arrived.': [769], 'Keith': [772, 964], 'Porter': [773, 787], 'seen': [777], 'endoplasmic': [779, 969], 'reticulum': [780, 970], 'studded': [783], 'ribosomes': [784], 'and,': [785], 'whereas': [786], 'saw': [788, 798, 1615, 1712], 'structure': [791], 'function,': [794], 'motif': [800, 848], 'clue': [803], 'function': [805, 1435], 'form': [808], 'actionable': [810], 'experiments.': [811], 'When': [812], 'joined': [814], 'lab,': [817], 'soaked': [819], 'gestalt.': [822], 'Most': [823], 'labs': [826], 'European': [834], 'leader,': [835], '“gestalt”': [839], 'inaccurate': [843], 'way': [844], 'describe': [846], 'labs.': [851], '(A': [852], 'few': [853], 'years': [854, 923, 1608], 'later,': [855], 'James': [856], 'Darnell,': [857], 'armed': [858], 'grant': [861], 'Lucille': [864], 'P.': [865], 'Markey': [866], 'Trust,': [867], 'ushered': [868], 'opened': [876], 'door': [878], 'appointments': [881], 'junior': [883], 'talent': [884], 'higher': [886], 'ranks—a': [887], 'event': [889], 'has': [891, 1386, 1505], 'success.)The': [895], 'notion': [896, 950], 'membrane': [898, 918, 956, 991], 'proteins': [899, 984, 998, 1025, 1489], 'somehow': [900], 'slip': [901], 'preexisting': [903, 914], 'membranes': [904], 'simple': [907], 'ΔG': [908], 'and/or': [909], 'ΔS': [910], 'event,': [911], 'given': [912], 'thermodynamics': [915], '(descended': [919], 'over': [920], 'billions': [921], 'Earth),': [927], 'main': [932], 'features': [933], 'movie': [938], 'house': [939], 'half': [944], 'ran': [951], 'bacterial': [955, 1223], 'field': [957], '(to': [958], 'we': [960, 1109, 1861], 'return),': [962], "Porter's": [965], 'discovery': [966, 1408, 1653], '(ER)': [971], 'gave': [972], 'rise': [973], 'maybe': [978], 'more.': [982], 'Membrane': [983], 'indeed': [986], 'assemble': [987], 'ER': [990, 1296, 1356], 'formal': [994], 'constituent,': [995], 'other': [997, 1514], 'headed': [1000], 'elsewhere,': [1001], 'namely': [1002], 'This,': [1007], 'course,': [1009], 'canon': [1012], 'metazoan': [1014], 'Eukarya,': [1018], 'ER-based': [1022], 'delivery': [1023], 'exterior': [1028], 'became': [1029, 1797], 'foothold.In': [1032], '1975,': [1033], 'associate': [1037], 'Bernhard': [1038], 'Dobberstein': [1039], 'published': [1040], 'stunning': [1042], 'showed': [1047, 1308, 1548], 'N-terminal': [1050, 1325], 'sequence': [1051], 'targets': [1052], 'nascent': [1054, 1282, 1352], 'polypeptide': [1055, 1353], 'ER.': [1058], 'They': [1059, 1271], 'erected': [1060], '“signal': [1062], 'peptide': [1063, 1159, 1327], 'hypothesis”': [1064], 'capture': [1066], 'findings.': [1068], 'taught': [1072, 1553], 'Günter,': [1073], 'naming': [1074], 'very': [1077], 'important.': [1078], 'In': [1079, 1121, 1173, 1298], 'molecular': [1080, 1885], 'Jacob': [1082], 'Monod': [1084], 'priests': [1087], 'art': [1090], '(i.e.,': [1091], '“operon”),': [1093], 'elegant': [1096], 'eloquent': [1098], 'name': [1099], 'quite': [1106], 'new.And': [1107], 'yet,': [1108], 'ask': [1112], 'whether': [1113, 1244], 'anything': [1116, 1742], 'under': [1118, 1963, 1978], 'sun.': [1120], 'antibody': [1124], 'synthesis,': [1125], 'César': [1126], 'Milstein': [1127, 1152], 'Cambridge,': [1129], 'England,': [1130], 'observed': [1132], 'higher-molecular-weight': [1133], 'precursors': [1134], 'speculated': [1136], 'reflected': [1139], 'kind': [1141], 'tag': [1143], 'either': [1145, 1384], 'processing': [1146], 'or': [1147], 'export': [1148, 1460], 'cell.': [1151], 'bitterly': [1155], 'resent': [1156], 'signal': [1158, 1280, 1287, 1313, 1326], 'hypothesis': [1160, 1181, 1205], 'colleagues': [1163], 'discovered': [1164, 1272, 1425, 1483], 'disputed': [1167], 'priority': [1169], 'idea.': [1172], 'my': [1174, 1423, 1605], 'opinion,': [1175], 'reaching': [1178], 'observation,': [1184], 'only': [1189, 1809], 'possibilities.': [1193], 'Dobberstien': [1197], 'stronger': [1200], 'legs': [1201], 'soon': [1208], 'followed': [1209], 'up': [1210], 'powerful': [1212, 1591, 1905], 'mechanistic': [1213], 'discoveries': [1214, 1363], '(vide': [1215], 'infra).': [1216], 'There': [1217], 'controversy': [1220], 'camp': [1224], 'M13': [1229], 'phage': [1230], 'William': [1233], 'Wickner.': [1234], 'led': [1236, 1263, 1392, 1464], 'unpleasantness': [1239], 'issue': [1242], 'secretion': [1246, 1366], 'process': [1247], 'driven.The': [1250], 'subsequent': [1251, 1299, 1822], 'arrival': [1252], 'Peter': [1254, 1405], 'Walter': [1255, 1301], 'Reid': [1257], 'Gilmore': [1258], 'lab': [1262, 1307, 1424, 1443, 1512, 1816], 'second': [1266, 1434, 1769], 'step.': [1270], 'machine': [1274, 1369], 'propelled': [1276], 'translocation': [1278], 'peptide-bearing': [1281], 'polypeptides': [1283], 'ER—the': [1286], 'recognition': [1288, 1314], '(SRP)': [1290], 'receptor': [1293], 'membrane.': [1297], 'work,': [1300], 'machine,': [1311], 'particle,': [1315], 'RNA–protein': [1318], 'complex': [1319], 'arrests': [1321], 'translation': [1322], 'after': [1323, 1970], 'synthesized.': [1329], 'On': [1330], 'docking': [1332], 'ER-located': [1335], 'SRP': [1336, 1411, 1431], 'receptor,': [1337], 'translational': [1339, 1347], 'block': [1340], 'released,': [1342], 'now': [1343, 1517], '“forcing”': [1344], 'resumed': [1346], 'elongation': [1348], 'place': [1350], 'channel,': [1357], 'later': [1358, 1391, 1444], 'dubbed': [1359], '“translocon.”': [1361], 'These': [1362, 1389], 'accomplishes': [1371], 'among': [1374], 'greatest': [1376], 'exemplifications': [1377], 'biochemistry': [1379], 'informing': [1380], 'discipline': [1385], 'ever': [1387, 1664], 'had.': [1388], 'advances': [1390, 1467], 'findings,': [1396], 'unfolded': [1400], 'response': [1402], 'pioneered': [1403], 'Walter.': [1406], 'reached': [1413], 'back': [1414], 'ancient': [1420, 1452], 'nucleolus,': [1421], 'site': [1429], 'assembly,': [1432], 'organelle,': [1438], 'beyond': [1439], 'ribosome': [1440], 'synthesis.The': [1441], 'delved': [1445], 'how': [1447], 'nucleus': [1449, 1484], '(possibly': [1450], 'endosymbiont': [1453], "today's": [1455], 'eukaryotic': [1456], 'cells)': [1457], 'manages': [1458], 'import.': [1462], 'field,': [1470], 'moving': [1474], 'bit': [1476], 'sluggishly': [1477], 'before.': [1478], 'Others': [1479], 'localization': [1485], 'signals': [1486], 'mechanism': [1492], 'remained': [1493], 'unresolved': [1495], 'problem.': [1496], 'Today,': [1497], 'definitive': [1499], 'description': [1500], 'nuclear': [1502], 'pore': [1503], 'complexes': [1504], 'accomplishment': [1508], 'disciples': [1515], 'there,': [1516], 'upward': [1519], 'promotion': [1520], 'play,': [1525], 'just': [1526], 'promoted.Günter': [1531], 'attracted': [1533], 'legions': [1534, 1802], 'brilliant': [1536], 'students': [1537, 1804], 'postdocs,': [1539], 'scientists': [1541], 'charisma': [1544], 'do.': [1546], '“the': [1550], 'ropes”': [1551], 'skills': [1555], 'needed': [1556], 'compete': [1558], 'often': [1561], 'tough': [1562], 'forum': [1563], 'won': [1570], 'wings,': [1571], 'while': [1572], 'conveying': [1574], 'passion': [1576], 'wanting': [1578], 'go': [1581], 'do': [1584, 1863], 'well.': [1585], 'His': [1586, 1650, 1748, 1768], 'trainees': [1587], 'written': [1589], 'remembrance': [1592], 'captures': [1594], 'beloved': [1596, 1844], 'mentor': [1597], 'perfect': [1599], '(Blobel': [1601], 'Lab': [1602, 1878], 'Trainees,': [1603], '2018).In': [1604], 'nearly': [1606], '50': [1607], 'knowing': [1610], 'open': [1617], 'mind': [1618], 'generous': [1621], 'demeanor.': [1622], 'kept': [1624], 'humor': [1628], 'close': [1629], 'chest': [1632], 'those': [1635], 'occasions': [1636], 'when': [1637, 1685, 1795], 'spontaneously': [1639], 'broke': [1640], 'forth,': [1641], 'hearty': [1643], 'laugh': [1644], 'almost': [1645, 1695], 'walls': [1648], 'rumble.': [1649], 'enthusiasm': [1651], 'infectious': [1656], 'any': [1660, 1840], 'scientist': [1661], 'known,': [1665], 'passionate': [1668], 'desire': [1669], 'instill': [1671], 'next': [1675], 'generation': [1676], 'signature': [1679], 'mentorship.As': [1682], 'know,': [1684], 'received': [1687], 'Nobel': [1689], 'Prize': [1690], '(unshared)': [1691], 'donated': [1693], '$1': [1696], 'million': [1697], 'restoration': [1700], 'cathedral': [1704], 'synagogue': [1706], 'whose': [1709], 'ruins': [1710], 'boy,': [1716], 'image': [1718], 'never': [1721], 'left': [1722], 'him.': [1723], 'reflect': [1726], 'about': [1729, 1739], 'dear': [1731], 'friend': [1732], 'colleague.': [1734], 'may': [1736], 'say': [1737], 'him': [1740, 1812, 1866], 'than': [1741, 1868], 'else.Günter': [1743], 'experiences.': [1747], 'heartland,': [1753], 'benefitted': [1761], 'talented': [1764], 'understated': [1766], 'mentor.': [1767], 'palatial': [1773], 'center': [1774], 'biomedical': [1777], 'infused': [1782], 'extraordinary': [1785], 'style': [1786], 'intellect': [1788], 'Palade.': [1791], 'icon': [1799], 'postdocs': [1806], 'who': [1807], 'worked': [1810], 'exalted': [1815], 'moved': [1819], 'stations': [1823], 'United': [1827], 'States': [1828], 'abroad.We': [1830], 'see': [1833], 'likes': [1835], 'again': [1839], 'soon.': [1842], 'Our': [1843], 'colleague': [1845], 'immigrant': [1848], 'America': [1850], '“Dreamer”': [1853], 'use.': [1859], 'Nothing': [1860], 'honor': [1865], 'us': [1870], 'support': [1872], 'cause': [1874], 'memory.FOOTNOTESDOI:10.1091/mbc.E18-03-0160REFERENCESBlobel': [1877], 'Trainees': [1879], '(2018).': [1880], 'pioneer': [1883], 'J': [1888], 'Cell': [1889, 1897, 1920, 1929, 1961], 'Biol': [1890, 1928], '217,': [1891], '1163–1167.': [1892], 'Google': [1893, 1933], 'ScholarPederson': [1894], 'T': [1895], '(2013).': [1896], 'biology:': [1898], 'high-resolution': [1900], 'image,': [1901], 'viewed': [1902], 'lens.': [1906], 'Review': [1907], '“Entering': [1909], 'Unseen': [1911], 'World:': [1912], 'Founding': [1914], 'Laboratory': [1915], 'Origins': [1917], 'Modern': [1919], 'Biology,': [1921], '1910–1974,”': [1922], 'Carol': [1924], 'L.': [1925], 'Moberg.': [1926], 'Mol': [1927], '24,': [1930], '1260–1262.': [1931], 'Link,': [1932], 'ScholarFiguresReferencesRelatedDetails': [1934], 'Vol.': [1935], 'June': [1939], '01,': [1940], '20181271-1409': [1941], 'Metrics': [1942], 'Downloads': [1943], '&': [1944], 'Downloads:': [1946], '115': [1947], 'History': [1948], 'Information©': [1949], '2018': [1950], 'Pederson.': [1951], 'article': [1953], 'distributed': [1955], 'Society': [1959], 'license': [1964], 'author(s).': [1967], 'Two': [1968], 'months': [1969], 'publication': [1971], 'available': [1974], 'public': [1977], 'Attribution–Noncommercial–Share': [1980], 'Alike': [1981], '3.0': [1982], 'Unported': [1983], 'Creative': [1984], 'Commons': [1985], 'License': [1986], '(http://creativecommons.org/licenses/by-nc-sa/3.0).PDF': [1987], 'download': [1988]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2805556592', 'counts_by_year': [], 'updated_date': '2024-12-07T04:59:24.045168', 'created_date': '2018-06-13'}