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1394], 'data,': [1127, 1863], 'well': [1129, 1805], 'annotated': [1131], 'information,': [1132, 1165], 'define': [1134], 'predictive': [1138], 'Annotations': [1140], 'anything': [1143], 'listed': [1146], 'together': [1147], 'paper': [1150], 'linked': [1156], 'pathway.': [1159], 'By': [1160, 2351], 'multiple': [1162, 1770], 'levels': [1163], 'GenMiner': [1166], 'enables': [1167], 'easily': [1170], 'synthesize': [1171], 'previous': [1172], 'work': [1173], 'current': [1176], 'projects.': [1177], '(or': [1194], 'other': [1195, 1833, 2232], 'species).': [1196], 'overlap': [1198], 'similarities': [1207, 1398], 'differences': [1209, 1485], 'select': [1218], 'direct': [1224], 'future': [1225, 1266, 1766, 1787], 'relationship': [1232], 'volume,': [1237], 'linking': [1239], 'varied': [1240], 'compared,': [1249], 'search': [1251], 'shared': [1255], 'species.': [1257, 1469], 'Association': [1258], 'provides': [1262], 'directions': [1264], 'increased': [1269], 'validity': [1273], 'model.Another': 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'valuable': [1518, 1809, 1878], 'help': [1521, 1578], 'process.': [1526, 1590], 'Although': [1527], 'replace': [1531], 'traditional': [1532], 'experiments,': [1533], 'enhance': [1539], 'investigation': [1540], 'phenomenon': [1543], 'suggest': [1545], 'new': [1546], 'experiments': [1547], 'closed-loop': [1550], 'approach.': [1551], 'enable': [1554], 'test': [1557], 'hypotheses': [1558], 'explore': [1560, 1606], 'parameter': [1563], 'space': [1564], 'biological': [1567], 'difficult/impossible': [1574], 'experimentally,': [1575], 'increase': [1579], "researcher's": [1581], 'phenomena': [1585, 1608], 'considering': [1594], 'interest': [1610], 'across': [1611], 'temporal': [1612, 1654], 'spatial': [1614, 1651], 'scales.': [1615], 'Using': [1616, 1746], 'researcher': [1620], 'begin': [1622], 'constructing': [1624], 'cellular': [1626, 1637], 'based': [1628], 'cell': [1633, 1678, 1686, 2179], 'electrophysiology': [1634], 'data).': [1635], 'tissue': [1648], 'featuring': [1649], 'unique': [1650, 1661], 'scales,10': [1655], 'will': [1657, 1928], 'informed': [1659], 'magnetic': [1664], 'resonance': [1665], 'imaging': [1666], 'data)': [1667], 'governed': [1669], 'distinct': [1671], 'mathematics/biophysics.': [1672], 'components': [1674], 'fitted': [1677], 'transferred': [1682], 'existing': [1684], 'fit': [1689], 'scaled': [1691], 'develop': [1693], 'animals.': [1699], 'Examination': [1700], 'aspects': [1704], 'inform': [1714, 1739], 'vivo': [1719], '(by': [1722], 'comparing': [1723], 'animal,': [1730], 'example).': [1732], 'Experiments': [1733], 'closed-loop,': [1749], 'iterative': [1750], 'approach,': [1751], 'computer': [1752], 'simulation': [1753], 'tight': [1756], 'coupling': [1757], 'enhancing': [1763], 'expediting': [1765], 'research.We': [1767], 'discussed': [1769], 'facilitate': [1778], 'endeavor': [1780], 'high-quality': [1782], 'translation).': [1788], 'Full': [1789], 'assays': [1791], 'wealth': [1794], 'mined': [1807], 'insights.': [1810], 'Furthermore,': [1811], 'increasing': [1815], 'valid': [1829], 'clustering.': [1839], 'Ideally,': [1840], 'selection;': [1852], 'sometimes': [1857], 'gather': [1861], 'successful': [1864], 'performed': [1868], 'phenotype': [1871], 'alone.': [1872], 'Finally,': [1873], 'resource': [1879], 'reducing': [1881], 'gap': [1883], 'accelerating': [1889], 'translation/translation': [1892], 'loop.': [1893], 'aid': [1904], 'choice': [1907], 'species': [1909], 'enabling': [1914], 'detailed': [1917], 'comparison.': [1918], 'As': [1919], 'quantity': [1921], 'increases,': [1926], 'become': [1929], 'push': [1934], 'boundaries': [1936], 'mining,': [1939], 'maximize': [1945], 'impactful': [1949], 'studies.Sources': [1951], 'FundingWe': [1953], 'supported': [1955], 'National': [1958], 'Institutes': [1959], 'grants': [1962], 'HL135096,': [1963], 'HL134824,': [1964], 'HL114893': [1966], 'T.J.': [1968], 'AG057046,': [1971], 'HL139348,': [1972], 'NR012618,': [1973], 'ES019923': [1975], 'L.E.': [1977], 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