Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2803732764', 'doi': 'https://doi.org/10.1007/s00018-018-2836-6', 'title': 'Roles of heat shock factor 1 beyond the heat shock response', 'display_name': 'Roles of heat shock factor 1 beyond the heat shock response', 'publication_year': 2018, 'publication_date': '2018-05-17', 'ids': {'openalex': 'https://openalex.org/W2803732764', 'doi': 'https://doi.org/10.1007/s00018-018-2836-6', 'mag': '2803732764', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/29774376'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1007/s00018-018-2836-6', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S60362788', 'display_name': 'Cellular and Molecular Life Sciences', 'issn_l': '1420-682X', 'issn': ['1420-682X', '1420-9071'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310319965', 'host_organization_name': 'Springer Nature', 'host_organization_lineage': ['https://openalex.org/P4310319965'], 'host_organization_lineage_names': ['Springer Nature'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'review', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'green', 'oa_url': 'http://repo.lib.semmelweis.hu//bitstream/123456789/6806/1/Csermely-CMLS-18.pdf', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5059648584', 'display_name': 'János Barna', 'orcid': 'https://orcid.org/0000-0002-9242-0939'}, 'institutions': [{'id': 'https://openalex.org/I106118109', 'display_name': 'Eötvös Loránd University', 'ror': 'https://ror.org/01jsq2704', 'country_code': 'HU', 'type': 'education', 'lineage': ['https://openalex.org/I106118109']}], 'countries': ['HU'], 'is_corresponding': False, 'raw_author_name': 'János Barna', 'raw_affiliation_strings': ['Department of Genetics, Eötvös Loránd University, Pázmány Péter Stny. 1/C, Budapest, 1117, Hungary'], 'affiliations': [{'raw_affiliation_string': 'Department of Genetics, Eötvös Loránd University, Pázmány Péter Stny. 1/C, Budapest, 1117, Hungary', 'institution_ids': ['https://openalex.org/I106118109']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5081215274', 'display_name': 'Péter Csermely', 'orcid': 'https://orcid.org/0000-0001-9234-0659'}, 'institutions': [{'id': 'https://openalex.org/I101202996', 'display_name': 'Semmelweis University', 'ror': 'https://ror.org/01g9ty582', 'country_code': 'HU', 'type': 'education', 'lineage': ['https://openalex.org/I101202996']}], 'countries': ['HU'], 'is_corresponding': False, 'raw_author_name': 'Péter Csermely', 'raw_affiliation_strings': ['Department of Medical Chemistry, Semmelweis University, Budapest, Hungary'], 'affiliations': [{'raw_affiliation_string': 'Department of Medical Chemistry, Semmelweis University, Budapest, Hungary', 'institution_ids': ['https://openalex.org/I101202996']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5029503476', 'display_name': 'Tibor Vellai', 'orcid': 'https://orcid.org/0000-0002-3520-2572'}, 'institutions': [{'id': 'https://openalex.org/I106118109', 'display_name': 'Eötvös Loránd University', 'ror': 'https://ror.org/01jsq2704', 'country_code': 'HU', 'type': 'education', 'lineage': ['https://openalex.org/I106118109']}], 'countries': ['HU'], 'is_corresponding': False, 'raw_author_name': 'Tibor Vellai', 'raw_affiliation_strings': ['MTA-ELTE Genetics Research Group, Eötvös Loránd University, Budapest, Hungary'], 'affiliations': [{'raw_affiliation_string': 'MTA-ELTE Genetics Research Group, Eötvös Loránd University, Budapest, Hungary', 'institution_ids': ['https://openalex.org/I106118109']}]}], 'countries_distinct_count': 1, 'institutions_distinct_count': 2, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': {'value': 3290, 'currency': 'EUR', 'value_usd': 4290, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 2.509, 'has_fulltext': True, 'fulltext_origin': 'pdf', 'cited_by_count': 151, 'citation_normalized_percentile': {'value': 0.999734, 'is_in_top_1_percent': True, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 99, 'max': 100}, 'biblio': {'volume': '75', 'issue': '16', 'first_page': '2897', 'last_page': '2916'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10934', 'display_name': 'Molecular Chaperones in Protein Folding and Disease', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10934', 'display_name': 'Molecular Chaperones in Protein Folding and Disease', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T11150', 'display_name': 'Endoplasmic Reticulum Stress and Unfolded Protein Response', 'score': 0.9984, 'subfield': {'id': 'https://openalex.org/subfields/1307', 'display_name': 'Cell Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10676', 'display_name': 'Molecular Mechanisms of Aging and Longevity', 'score': 0.965, 'subfield': {'id': 'https://openalex.org/subfields/1302', 'display_name': 'Aging'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/hsf1', 'display_name': 'HSF1', 'score': 0.97271514}, {'id': 'https://openalex.org/keywords/heat-shock-factor', 'display_name': 'Heat shock factor', 'score': 0.84309757}, {'id': 'https://openalex.org/keywords/proteostasis', 'display_name': 'Proteostasis', 'score': 0.69035095}, {'id': 'https://openalex.org/keywords/hspa12a', 'display_name': 'HSPA12A', 'score': 0.6502302}, {'id': 'https://openalex.org/keywords/cellular-stress-response', 'display_name': 'Cellular stress response', 'score': 0.5855611}, {'id': 'https://openalex.org/keywords/heat-shock-proteins', 'display_name': 'Heat Shock Proteins', 'score': 0.569936}, {'id': 'https://openalex.org/keywords/hspa4', 'display_name': 'HSPA4', 'score': 0.47487733}], 'concepts': [{'id': 'https://openalex.org/C2776667301', 'wikidata': 'https://www.wikidata.org/wiki/Q18027324', 'display_name': 'HSF1', 'level': 5, 'score': 0.97271514}, {'id': 'https://openalex.org/C52981337', 'wikidata': 'https://www.wikidata.org/wiki/Q24782817', 'display_name': 'Heat shock factor', 'level': 5, 'score': 0.84309757}, {'id': 'https://openalex.org/C95444343', 'wikidata': 'https://www.wikidata.org/wiki/Q7141', 'display_name': 'Cell biology', 'level': 1, 'score': 0.74235517}, {'id': 'https://openalex.org/C205260736', 'wikidata': 'https://www.wikidata.org/wiki/Q418939', 'display_name': 'Heat shock protein', 'level': 3, 'score': 0.7314936}, {'id': 'https://openalex.org/C137984847', 'wikidata': 'https://www.wikidata.org/wiki/Q1621258', 'display_name': 'Heat shock', 'level': 4, 'score': 0.71305555}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.69496113}, {'id': 'https://openalex.org/C2781452922', 'wikidata': 'https://www.wikidata.org/wiki/Q2892805', 'display_name': 'Proteostasis', 'level': 2, 'score': 0.69035095}, {'id': 'https://openalex.org/C103474985', 'wikidata': 'https://www.wikidata.org/wiki/Q24786671', 'display_name': 'HSPA12A', 'level': 5, 'score': 0.6502302}, {'id': 'https://openalex.org/C86339819', 'wikidata': 'https://www.wikidata.org/wiki/Q407384', 'display_name': 'Transcription factor', 'level': 3, 'score': 0.61108035}, {'id': 'https://openalex.org/C2780096491', 'wikidata': 'https://www.wikidata.org/wiki/Q60574533', 'display_name': 'Cellular stress response', 'level': 4, 'score': 0.5855611}, {'id': 'https://openalex.org/C158617107', 'wikidata': 'https://www.wikidata.org/wiki/Q79927', 'display_name': 'Endoplasmic reticulum', 'level': 2, 'score': 0.5712152}, {'id': 'https://openalex.org/C27740335', 'wikidata': 'https://www.wikidata.org/wiki/Q14878333', 'display_name': 'Proteasome', 'level': 2, 'score': 0.5689786}, {'id': 'https://openalex.org/C139447449', 'wikidata': 'https://www.wikidata.org/wiki/Q14633900', 'display_name': 'Unfolded protein response', 'level': 3, 'score': 0.53683156}, {'id': 'https://openalex.org/C203522944', 'wikidata': 'https://www.wikidata.org/wiki/Q288322', 'display_name': 'Autophagy', 'level': 3, 'score': 0.4858727}, {'id': 'https://openalex.org/C197199866', 'wikidata': 'https://www.wikidata.org/wiki/Q18027348', 'display_name': 'HSPA4', 'level': 5, 'score': 0.47487733}, {'id': 'https://openalex.org/C68991219', 'wikidata': 'https://www.wikidata.org/wiki/Q419102', 'display_name': 'Hsp70', 'level': 4, 'score': 0.37561274}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.2906255}, {'id': 'https://openalex.org/C54355233', 'wikidata': 'https://www.wikidata.org/wiki/Q7162', 'display_name': 'Genetics', 'level': 1, 'score': 0.23408094}, {'id': 'https://openalex.org/C190283241', 'wikidata': 'https://www.wikidata.org/wiki/Q14599311', 'display_name': 'Apoptosis', 'level': 2, 'score': 0.17940792}, {'id': 'https://openalex.org/C78604142', 'wikidata': 'https://www.wikidata.org/wiki/Q1640582', 'display_name': 'Fight-or-flight response', 'level': 3, 'score': 0.10441777}], 'mesh': [{'descriptor_ui': 'D002468', 'descriptor_name': 'Cell Physiological Phenomena', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': True}, {'descriptor_ui': 'D000076249', 'descriptor_name': 'Heat Shock Transcription Factors', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': True}, {'descriptor_ui': 'D006360', 'descriptor_name': 'Heat-Shock Proteins', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': True}, {'descriptor_ui': 'D018869', 'descriptor_name': 'Heat-Shock Response', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': True}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D017209', 'descriptor_name': 'Apoptosis', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D001343', 'descriptor_name': 'Autophagy', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D005786', 'descriptor_name': 'Gene Expression Regulation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 3, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1007/s00018-018-2836-6', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S60362788', 'display_name': 'Cellular and Molecular Life Sciences', 'issn_l': '1420-682X', 'issn': ['1420-682X', '1420-9071'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310319965', 'host_organization_name': 'Springer Nature', 'host_organization_lineage': ['https://openalex.org/P4310319965'], 'host_organization_lineage_names': ['Springer Nature'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': True, 'landing_page_url': 'http://repo.lib.semmelweis.hu//handle/123456789/6806', 'pdf_url': 'http://repo.lib.semmelweis.hu//bitstream/123456789/6806/1/Csermely-CMLS-18.pdf', 'source': {'id': 'https://openalex.org/S4306402199', 'display_name': 'Semmelweis University Repository (Semmelweis University)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I101202996', 'host_organization_name': 'Semmelweis University', 'host_organization_lineage': ['https://openalex.org/I101202996'], 'host_organization_lineage_names': ['Semmelweis University'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'submittedVersion', 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/29774376', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'http://repo.lib.semmelweis.hu//handle/123456789/6806', 'pdf_url': 'http://repo.lib.semmelweis.hu//bitstream/123456789/6806/1/Csermely-CMLS-18.pdf', 'source': {'id': 'https://openalex.org/S4306402199', 'display_name': 'Semmelweis University Repository (Semmelweis University)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I101202996', 'host_organization_name': 'Semmelweis University', 'host_organization_lineage': ['https://openalex.org/I101202996'], 'host_organization_lineage_names': ['Semmelweis University'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'submittedVersion', 'is_accepted': False, 'is_published': False}, 'sustainable_development_goals': [{'display_name': 'Good health and well-being', 'score': 0.67, 'id': 'https://metadata.un.org/sdg/3'}], 'grants': [{'funder': 'https://openalex.org/F4320321994', 'funder_display_name': 'Hungarian Scientific Research Fund', 'award_id': 'K115378'}, {'funder': 'https://openalex.org/F4320321994', 'funder_display_name': 'Hungarian Scientific Research Fund', 'award_id': 'NK78012'}, {'funder': 'https://openalex.org/F4320322193', 'funder_display_name': 'Nemzeti Kutatási és Technológiai Hivatal', 'award_id': 'VEKOP-2.3.2-16-2017-00014'}], 'datasets': [], 'versions': [], 'referenced_works_count': 214, 'referenced_works': ['https://openalex.org/W1502386496', 'https://openalex.org/W1509643601', 'https://openalex.org/W153442697', 'https://openalex.org/W1534544091', 'https://openalex.org/W1540709528', 'https://openalex.org/W1621199903', 'https://openalex.org/W1683598352', 'https://openalex.org/W1759362230', 'https://openalex.org/W1835157090', 'https://openalex.org/W1904178031', 'https://openalex.org/W1964184380', 'https://openalex.org/W1966913704', 'https://openalex.org/W1967809393', 'https://openalex.org/W1973838213', 'https://openalex.org/W1974136307', 'https://openalex.org/W1975195662', 'https://openalex.org/W1975200549', 'https://openalex.org/W1975358590', 'https://openalex.org/W1976065095', 'https://openalex.org/W1979479771', 'https://openalex.org/W1980902269', 'https://openalex.org/W1981593440', 'https://openalex.org/W1983351509', 'https://openalex.org/W1984422392', 'https://openalex.org/W1985872632', 'https://openalex.org/W1988857689', 'https://openalex.org/W1992779495', 'https://openalex.org/W1993069510', 'https://openalex.org/W1994149899', 'https://openalex.org/W1998058878', 'https://openalex.org/W1998323098', 'https://openalex.org/W1998586548', 'https://openalex.org/W2001341780', 'https://openalex.org/W2001980122', 'https://openalex.org/W2002628931', 'https://openalex.org/W2002669376', 'https://openalex.org/W2004360525', 'https://openalex.org/W2005131012', 'https://openalex.org/W2005202590', 'https://openalex.org/W2006466159', 'https://openalex.org/W2008536823', 'https://openalex.org/W2010142538', 'https://openalex.org/W2011810742', 'https://openalex.org/W2012091442', 'https://openalex.org/W2013486761', 'https://openalex.org/W2016192239', 'https://openalex.org/W2017151000', 'https://openalex.org/W2019766459', 'https://openalex.org/W2021435809', 'https://openalex.org/W2022501802', 'https://openalex.org/W2022777279', 'https://openalex.org/W2023431124', 'https://openalex.org/W2023598683', 'https://openalex.org/W2025732015', 'https://openalex.org/W2027069379', 'https://openalex.org/W2028466753', 'https://openalex.org/W2029019156', 'https://openalex.org/W2029785188', 'https://openalex.org/W2031473689', 'https://openalex.org/W2031793125', 'https://openalex.org/W2034503993', 'https://openalex.org/W2035218158', 'https://openalex.org/W2036101230', 'https://openalex.org/W2037385652', 'https://openalex.org/W2037611748', 'https://openalex.org/W2037850046', 'https://openalex.org/W2037911961', 'https://openalex.org/W2039470834', 'https://openalex.org/W2039755487', 'https://openalex.org/W2040327353', 'https://openalex.org/W2040359453', 'https://openalex.org/W2040601363', 'https://openalex.org/W2042219465', 'https://openalex.org/W2043005875', 'https://openalex.org/W2044089985', 'https://openalex.org/W2046016011', 'https://openalex.org/W2046314862', 'https://openalex.org/W2046640957', 'https://openalex.org/W2053119214', 'https://openalex.org/W2054073100', 'https://openalex.org/W2054712075', 'https://openalex.org/W2055525599', 'https://openalex.org/W2058261286', 'https://openalex.org/W2060977907', 'https://openalex.org/W2061091970', 'https://openalex.org/W2062771689', 'https://openalex.org/W2062779626', 'https://openalex.org/W2062841269', 'https://openalex.org/W2063117081', 'https://openalex.org/W2063623078', 'https://openalex.org/W2064391294', 'https://openalex.org/W2064451353', 'https://openalex.org/W2065785051', 'https://openalex.org/W2066670143', 'https://openalex.org/W2068073076', 'https://openalex.org/W2070056754', 'https://openalex.org/W2072479337', 'https://openalex.org/W2073204556', 'https://openalex.org/W2073710122', 'https://openalex.org/W2073786084', 'https://openalex.org/W2075123763', 'https://openalex.org/W2075604280', 'https://openalex.org/W2075703485', 'https://openalex.org/W2077404705', 'https://openalex.org/W2080659767', 'https://openalex.org/W2081787112', 'https://openalex.org/W2081910903', 'https://openalex.org/W2084644507', 'https://openalex.org/W2084795601', 'https://openalex.org/W2086085489', 'https://openalex.org/W2092985720', 'https://openalex.org/W2093304538', 'https://openalex.org/W2094730469', 'https://openalex.org/W2096645082', 'https://openalex.org/W2097749282', 'https://openalex.org/W2100810063', 'https://openalex.org/W2102042089', 'https://openalex.org/W2103959519', 'https://openalex.org/W2108324435', 'https://openalex.org/W2108398067', 'https://openalex.org/W2108808474', 'https://openalex.org/W2110026725', 'https://openalex.org/W2111405344', 'https://openalex.org/W2111599440', 'https://openalex.org/W2111877659', 'https://openalex.org/W2114587202', 'https://openalex.org/W2114746301', 'https://openalex.org/W2115871248', 'https://openalex.org/W2116070992', 'https://openalex.org/W2116902247', 'https://openalex.org/W2118292263', 'https://openalex.org/W2119652242', 'https://openalex.org/W2119864607', 'https://openalex.org/W2121699992', 'https://openalex.org/W2123737072', 'https://openalex.org/W2124032036', 'https://openalex.org/W2124310857', 'https://openalex.org/W2124526610', 'https://openalex.org/W2127906347', 'https://openalex.org/W2128344746', 'https://openalex.org/W2128923889', 'https://openalex.org/W2130527641', 'https://openalex.org/W2130543809', 'https://openalex.org/W2132176657', 'https://openalex.org/W2132702191', 'https://openalex.org/W2135686999', 'https://openalex.org/W2136002979', 'https://openalex.org/W2137417707', 'https://openalex.org/W2137440237', 'https://openalex.org/W2137819605', 'https://openalex.org/W2139393817', 'https://openalex.org/W2140375810', 'https://openalex.org/W2141322853', 'https://openalex.org/W2141444248', 'https://openalex.org/W2143632993', 'https://openalex.org/W2143659623', 'https://openalex.org/W2145760315', 'https://openalex.org/W2145953486', 'https://openalex.org/W2151221308', 'https://openalex.org/W2151897497', 'https://openalex.org/W2152217159', 'https://openalex.org/W2153040065', 'https://openalex.org/W2153475997', 'https://openalex.org/W2153599010', 'https://openalex.org/W2154338704', 'https://openalex.org/W2154620292', 'https://openalex.org/W2154827429', 'https://openalex.org/W2156110752', 'https://openalex.org/W2157057023', 'https://openalex.org/W2157360354', 'https://openalex.org/W2158488559', 'https://openalex.org/W2158648222', 'https://openalex.org/W2159271990', 'https://openalex.org/W2160167196', 'https://openalex.org/W2161463238', 'https://openalex.org/W2162092051', 'https://openalex.org/W2162695817', 'https://openalex.org/W2164663225', 'https://openalex.org/W2165178917', 'https://openalex.org/W2166185546', 'https://openalex.org/W2167439903', 'https://openalex.org/W2168333121', 'https://openalex.org/W2169210465', 'https://openalex.org/W2169466265', 'https://openalex.org/W2170634816', 'https://openalex.org/W2184152595', 'https://openalex.org/W2191837935', 'https://openalex.org/W2213407375', 'https://openalex.org/W2249259354', 'https://openalex.org/W2259023643', 'https://openalex.org/W2287992997', 'https://openalex.org/W2299409781', 'https://openalex.org/W2306540679', 'https://openalex.org/W2319595593', 'https://openalex.org/W2325287326', 'https://openalex.org/W2330783056', 'https://openalex.org/W2377706331', 'https://openalex.org/W2407890715', 'https://openalex.org/W2420903908', 'https://openalex.org/W2486890521', 'https://openalex.org/W2487443016', 'https://openalex.org/W2508956795', 'https://openalex.org/W2521298391', 'https://openalex.org/W2526226642', 'https://openalex.org/W2551749690', 'https://openalex.org/W2566869110', 'https://openalex.org/W2587866198', 'https://openalex.org/W2588627185', 'https://openalex.org/W2601284491', 'https://openalex.org/W2682402162', 'https://openalex.org/W2743018412', 'https://openalex.org/W2750745925', 'https://openalex.org/W4293409298', 'https://openalex.org/W86778626'], 'related_works': ['https://openalex.org/W2803732764', 'https://openalex.org/W2323127830', 'https://openalex.org/W2154512403', 'https://openalex.org/W2146363912', 'https://openalex.org/W2146142695', 'https://openalex.org/W2102042089', 'https://openalex.org/W2035470335', 'https://openalex.org/W1983404919', 'https://openalex.org/W1933920814', 'https://openalex.org/W1555441628'], 'abstract_inverted_index': {'Various': [0], 'stress': [1, 155], 'factors': [2], 'leading': [3], 'to': [4, 22], 'protein': [5, 24, 122], 'damage': [6], 'induce': [7], 'the': [8, 17, 41, 83, 118], 'activation': [9, 84], 'of': [10, 85, 94, 98, 153], 'an': [11], 'evolutionarily': [12], 'conserved': [13], 'cell': [14, 133], 'protective': [15], 'mechanism,': [16], 'heat': [18, 55], 'shock': [19, 32, 56], 'response': [20, 123, 156], '(HSR),': [21], 'maintain': [23], 'homeostasis': [25], 'in': [26, 40, 65, 109], 'virtually': [27], 'all': [28], 'eukaryotic': [29], 'cells.': [30], 'Heat': [31], 'factor': [33, 50], '1': [34], '(HSF1)': [35], 'plays': [36], 'a': [37, 48, 90, 150], 'central': [38], 'role': [39], 'HSR.': [42], 'HSF1': [43, 81, 99, 107, 147], 'was': [44], 'initially': [45], 'known': [46], 'as': [47, 149], 'transcription': [49], 'that': [51], 'upregulates': [52], 'genes': [53, 97], 'encoding': [54], 'proteins': [57], '(HSPs),': [58], 'also': [59], 'called': [60], 'molecular': [61, 115], 'chaperones,': [62], 'which': [63], 'assist': [64], 'refolding': [66], 'or': [67], 'degrading': [68], 'injured': [69], 'intracellular': [70], 'proteins.': [71], 'However,': [72], 'recent': [73], 'accumulating': [74], 'evidence': [75], 'indicates': [76], 'multiple': [77], 'additional': [78], 'functions': [79], 'for': [80], 'beyond': [82], 'HSPs.': [86], 'Here,': [87], 'we': [88], 'present': [89], 'nearly': [91], 'comprehensive': [92], 'list': [93], 'non-HSP-related': [95], 'target': [96], 'identified': [100], 'so': [101], 'far.': [102], 'Through': [103], 'controlling': [104], 'these': [105], 'targets,': [106], 'acts': [108], 'diverse': [110], 'stress-induced': [111], 'cellular': [112, 154], 'processes': [113], 'and': [114, 124, 144], 'mechanisms,': [116], 'including': [117], 'endoplasmic': [119], 'reticulum': [120], 'unfolded': [121], 'ubiquitin–proteasome': [125], 'system,': [126], 'multidrug': [127], 'resistance,': [128], 'autophagy,': [129], 'apoptosis,': [130], 'immune': [131], 'response,': [132], 'growth': [134], 'arrest,': [135], 'differentiation': [136], 'underlying': [137], 'developmental': [138], 'diapause,': [139], 'chromatin': [140], 'remodelling,': [141], 'cancer': [142], 'development,': [143], 'ageing.': [145], 'Hence,': [146], 'emerges': [148], 'major': [151], 'orchestrator': [152], 'pathways.': [157]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2803732764', 'counts_by_year': [{'year': 2024, 'cited_by_count': 20}, {'year': 2023, 'cited_by_count': 17}, {'year': 2022, 'cited_by_count': 29}, {'year': 2021, 'cited_by_count': 34}, {'year': 2020, 'cited_by_count': 33}, {'year': 2019, 'cited_by_count': 14}, {'year': 2018, 'cited_by_count': 4}], 'updated_date': '2024-09-01T07:12:05.325235', 'created_date': '2018-06-01'}