Publication Information

{'id': 'https://openalex.org/W2800327377', 'doi': 'https://doi.org/10.1182/bloodadvances.2018016121', 'title': 'Hypomethylating agents in relapsed and refractory AML: outcomes and their predictors in a large international patient cohort', 'display_name': 'Hypomethylating agents in relapsed and refractory AML: outcomes and their predictors in a large international patient cohort', 'publication_year': 2018, 'publication_date': '2018-04-23', 'ids': {'openalex': 'https://openalex.org/W2800327377', 'doi': 'https://doi.org/10.1182/bloodadvances.2018016121', 'mag': '2800327377', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/29685952', 'pmcid': 'https://www.ncbi.nlm.nih.gov/pmc/articles/5916007'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1182/bloodadvances.2018016121', 'pdf_url': 'https://ashpublications.org/bloodadvances/article-pdf/2/8/923/880924/advances016121.pdf', 'source': {'id': 'https://openalex.org/S2764683450', 'display_name': 'Blood Advances', 'issn_l': '2473-9529', 'issn': ['2473-9529', '2473-9537'], 'is_oa': True, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': 'cc-by-nc-nd', 'license_id': 'https://openalex.org/licenses/cc-by-nc-nd', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'gold', 'oa_url': 'https://ashpublications.org/bloodadvances/article-pdf/2/8/923/880924/advances016121.pdf', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5013969487', 'display_name': 'Maximilian Stahl', 'orcid': 'https://orcid.org/0000-0002-1299-5901'}, 'institutions': [{'id': 'https://openalex.org/I32971472', 'display_name': 'Yale University', 'ror': 'https://ror.org/03v76x132', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I32971472']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Maximilian Stahl', 'raw_affiliation_strings': ['Section of Hematology, Department of Internal Medicine, Yale University School of Medicine, New Haven, CT;'], 'affiliations': [{'raw_affiliation_string': 'Section of Hematology, Department of Internal Medicine, Yale University School of Medicine, New Haven, CT;', 'institution_ids': ['https://openalex.org/I32971472']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5000296770', 'display_name': 'Michelle DeVeaux', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I32971472', 'display_name': 'Yale University', 'ror': 'https://ror.org/03v76x132', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I32971472']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Michelle DeVeaux', 'raw_affiliation_strings': ['Department of Biostatistics, Yale School of Public Health, New Haven, CT;'], 'affiliations': [{'raw_affiliation_string': 'Department of Biostatistics, Yale School of Public Health, New Haven, CT;', 'institution_ids': ['https://openalex.org/I32971472']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5003682435', 'display_name': 'Pau Montesinos', 'orcid': 'https://orcid.org/0000-0002-3275-5593'}, 'institutions': [{'id': 'https://openalex.org/I3019010403', 'display_name': 'Hospital Universitari i Politècnic La Fe', 'ror': 'https://ror.org/01ar2v535', 'country_code': 'ES', 'type': 'healthcare', 'lineage': ['https://openalex.org/I3019010403', 'https://openalex.org/I4210166036']}, {'id': 'https://openalex.org/I16097986', 'display_name': 'Universitat de València', 'ror': 'https://ror.org/043nxc105', 'country_code': 'ES', 'type': 'education', 'lineage': ['https://openalex.org/I16097986']}], 'countries': ['ES'], 'is_corresponding': False, 'raw_author_name': 'Pau Montesinos', 'raw_affiliation_strings': ['Department of Medicine, University of Valencia, Hospital Universitario y Politécnico La Fe, Valencia, Spain;'], 'affiliations': [{'raw_affiliation_string': 'Department of Medicine, University of Valencia, Hospital Universitario y Politécnico La Fe, Valencia, Spain;', 'institution_ids': ['https://openalex.org/I3019010403', 'https://openalex.org/I16097986']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5004876764', 'display_name': 'Raphaël Itzykson', 'orcid': 'https://orcid.org/0000-0003-2139-6262'}, 'institutions': [{'id': 'https://openalex.org/I4210144610', 'display_name': 'Hôpital Saint-Louis', 'ror': 'https://ror.org/049am9t04', 'country_code': 'FR', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210097159', 'https://openalex.org/I4210144610']}, {'id': 'https://openalex.org/I204730241', 'display_name': 'Université Paris Cité', 'ror': 'https://ror.org/05f82e368', 'country_code': 'FR', 'type': 'education', 'lineage': ['https://openalex.org/I204730241']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'Raphael Itzykson', 'raw_affiliation_strings': ['Section of Hematology, Saint-Louis Hospital, University Paris 7, Paris, France;'], 'affiliations': [{'raw_affiliation_string': 'Section of Hematology, Saint-Louis Hospital, University Paris 7, Paris, France;', 'institution_ids': ['https://openalex.org/I4210144610', 'https://openalex.org/I204730241']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5078887304', 'display_name': 'Ellen K. Ritchie', 'orcid': 'https://orcid.org/0000-0001-8150-5542'}, 'institutions': [{'id': 'https://openalex.org/I4210096498', 'display_name': 'Presbyterian Hospital', 'ror': 'https://ror.org/00n2w1t65', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1321404777', 'https://openalex.org/I4210096498']}, {'id': 'https://openalex.org/I2801107848', 'display_name': 'New York Hospital Queens', 'ror': 'https://ror.org/01j17xg39', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2801107848']}, {'id': 'https://openalex.org/I1340179700', 'display_name': 'NewYork–Presbyterian Hospital', 'ror': 'https://ror.org/03gzbrs57', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1340179700']}, {'id': 'https://openalex.org/I4387153466', 'display_name': 'Weill Cornell Medicine', 'ror': 'https://ror.org/02r109517', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I205783295', 'https://openalex.org/I4387153466']}, {'id': 'https://openalex.org/I205783295', 'display_name': 'Cornell University', 'ror': 'https://ror.org/05bnh6r87', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I205783295']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Ellen K. Ritchie', 'raw_affiliation_strings': ['Weill Cornell Medicine and New York Presbyterian Hospital, New York, NY;'], 'affiliations': [{'raw_affiliation_string': 'Weill Cornell Medicine and New York Presbyterian Hospital, New York, NY;', 'institution_ids': ['https://openalex.org/I4210096498', 'https://openalex.org/I2801107848', 'https://openalex.org/I1340179700', 'https://openalex.org/I4387153466', 'https://openalex.org/I205783295']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5055740968', 'display_name': 'Mikkael A. Sekeres', 'orcid': 'https://orcid.org/0000-0003-2009-6524'}, 'institutions': [{'id': 'https://openalex.org/I1316902750', 'display_name': 'Cleveland Clinic', 'ror': 'https://ror.org/03xjacd83', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1316902750']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Mikkael A. Sekeres', 'raw_affiliation_strings': ['Leukemia Program, Taussig Cancer Institute, Cleveland Clinic, Cleveland, OH;'], 'affiliations': [{'raw_affiliation_string': 'Leukemia Program, Taussig Cancer Institute, Cleveland Clinic, Cleveland, OH;', 'institution_ids': ['https://openalex.org/I1316902750']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5026865748', 'display_name': 'John Barnard', 'orcid': 'https://orcid.org/0000-0003-2403-8268'}, 'institutions': [{'id': 'https://openalex.org/I1316902750', 'display_name': 'Cleveland Clinic', 'ror': 'https://ror.org/03xjacd83', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1316902750']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'John D. Barnard', 'raw_affiliation_strings': ['Leukemia Program, Taussig Cancer Institute, Cleveland Clinic, Cleveland, OH;'], 'affiliations': [{'raw_affiliation_string': 'Leukemia Program, Taussig Cancer Institute, Cleveland Clinic, Cleveland, OH;', 'institution_ids': ['https://openalex.org/I1316902750']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5015755664', 'display_name': 'Nikolai A. Podoltsev', 'orcid': 'https://orcid.org/0000-0002-3657-778X'}, 'institutions': [{'id': 'https://openalex.org/I32971472', 'display_name': 'Yale University', 'ror': 'https://ror.org/03v76x132', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I32971472']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Nikolai A. Podoltsev', 'raw_affiliation_strings': ['Section of Hematology, Department of Internal Medicine, Yale University School of Medicine, New Haven, CT;'], 'affiliations': [{'raw_affiliation_string': 'Section of Hematology, Department of Internal Medicine, Yale University School of Medicine, New Haven, CT;', 'institution_ids': ['https://openalex.org/I32971472']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5009387581', 'display_name': 'Andrew M. Brunner', 'orcid': 'https://orcid.org/0000-0002-2169-4115'}, 'institutions': [{'id': 'https://openalex.org/I4210087915', 'display_name': 'Massachusetts General Hospital', 'ror': 'https://ror.org/002pd6e78', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210087915', 'https://openalex.org/I48633490']}, {'id': 'https://openalex.org/I136199984', 'display_name': 'Harvard University', 'ror': 'https://ror.org/03vek6s52', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I136199984']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Andrew M. Brunner', 'raw_affiliation_strings': ['Massachusetts General Hospital Cancer Center, Department of Hematology/Oncology, Harvard Medical School, Boston, MA;'], 'affiliations': [{'raw_affiliation_string': 'Massachusetts General Hospital Cancer Center, Department of Hematology/Oncology, Harvard Medical School, Boston, MA;', 'institution_ids': ['https://openalex.org/I4210087915', 'https://openalex.org/I136199984']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5010075752', 'display_name': 'Rami S. Komrokji', 'orcid': 'https://orcid.org/0000-0002-1876-5269'}, 'institutions': [{'id': 'https://openalex.org/I3019308854', 'display_name': 'Moffitt Cancer Center', 'ror': 'https://ror.org/01xf75524', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I3019308854']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Rami S. Komrokji', 'raw_affiliation_strings': ['Department of Malignant Hematology, Moffitt Cancer Center and Research Institute, Tampa, FL;'], 'affiliations': [{'raw_affiliation_string': 'Department of Malignant Hematology, Moffitt Cancer Center and Research Institute, Tampa, FL;', 'institution_ids': ['https://openalex.org/I3019308854']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5051793137', 'display_name': 'Vijaya Raj Bhatt', 'orcid': 'https://orcid.org/0000-0003-2513-0533'}, 'institutions': [{'id': 'https://openalex.org/I59130452', 'display_name': 'University of Nebraska Medical Center', 'ror': 'https://ror.org/00thqtb16', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I59130452']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Vijaya R. Bhatt', 'raw_affiliation_strings': ['Division of Oncology & Hematology, University of Nebraska Medical Center, Omaha, NE;'], 'affiliations': [{'raw_affiliation_string': 'Division of Oncology & Hematology, University of Nebraska Medical Center, Omaha, NE;', 'institution_ids': ['https://openalex.org/I59130452']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5008422091', 'display_name': 'Aref Al‐Kali', 'orcid': 'https://orcid.org/0000-0002-0824-3715'}, 'institutions': [{'id': 'https://openalex.org/I4210125099', 'display_name': 'Mayo Clinic in Arizona', 'ror': 'https://ror.org/03jp40720', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1330342723', 'https://openalex.org/I4210125099']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Aref Al-Kali', 'raw_affiliation_strings': ['Division of Hematology, Mayo Clinic, Rochester, MN;'], 'affiliations': [{'raw_affiliation_string': 'Division of Hematology, Mayo Clinic, Rochester, MN;', 'institution_ids': ['https://openalex.org/I4210125099']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5080661528', 'display_name': 'Thomas Cluzeau', 'orcid': 'https://orcid.org/0000-0002-6745-1127'}, 'institutions': [{'id': 'https://openalex.org/I3018988418', 'display_name': 'Centre Hospitalier Universitaire de Nice', 'ror': 'https://ror.org/05qsjq305', 'country_code': 'FR', 'type': 'healthcare', 'lineage': ['https://openalex.org/I201841394', 'https://openalex.org/I3018988418']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'Thomas Cluzeau', 'raw_affiliation_strings': ["Cote d'Azur University, Nice Sophia Antipolis University, Centre Hospitalier Universitaire de Nice, Nice, France;"], 'affiliations': [{'raw_affiliation_string': "Cote d'Azur University, Nice Sophia Antipolis University, Centre Hospitalier Universitaire de Nice, Nice, France;", 'institution_ids': ['https://openalex.org/I3018988418']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5091318797', 'display_name': 'Valeria Santini', 'orcid': 'https://orcid.org/0000-0002-5439-2172'}, 'institutions': [{'id': 'https://openalex.org/I4210115393', 'display_name': 'Azienda Ospedaliero-Universitaria Careggi', 'ror': 'https://ror.org/02crev113', 'country_code': 'IT', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210115393']}, {'id': 'https://openalex.org/I45084792', 'display_name': 'University of Florence', 'ror': 'https://ror.org/04jr1s763', 'country_code': 'IT', 'type': 'education', 'lineage': ['https://openalex.org/I45084792']}], 'countries': ['IT'], 'is_corresponding': False, 'raw_author_name': 'Valeria Santini', 'raw_affiliation_strings': ['Division of Hematology, University of Florence, Azienda Ospedaliero Universitaria Careggi, Florence, Italy;'], 'affiliations': [{'raw_affiliation_string': 'Division of Hematology, University of Florence, Azienda Ospedaliero Universitaria Careggi, Florence, Italy;', 'institution_ids': ['https://openalex.org/I4210115393', 'https://openalex.org/I45084792']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5010057352', 'display_name': 'Amir T. Fathi', 'orcid': 'https://orcid.org/0000-0003-4907-6447'}, 'institutions': [{'id': 'https://openalex.org/I4210087915', 'display_name': 'Massachusetts General Hospital', 'ror': 'https://ror.org/002pd6e78', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210087915', 'https://openalex.org/I48633490']}, {'id': 'https://openalex.org/I136199984', 'display_name': 'Harvard University', 'ror': 'https://ror.org/03vek6s52', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I136199984']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Amir T. Fathi', 'raw_affiliation_strings': ['Massachusetts General Hospital Cancer Center, Department of Hematology/Oncology, Harvard Medical School, Boston, MA;'], 'affiliations': [{'raw_affiliation_string': 'Massachusetts General Hospital Cancer Center, Department of Hematology/Oncology, Harvard Medical School, Boston, MA;', 'institution_ids': ['https://openalex.org/I4210087915', 'https://openalex.org/I136199984']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5012863731', 'display_name': 'Gail J. Roboz', 'orcid': 'https://orcid.org/0000-0002-0384-3658'}, 'institutions': [{'id': 'https://openalex.org/I4210096498', 'display_name': 'Presbyterian Hospital', 'ror': 'https://ror.org/00n2w1t65', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1321404777', 'https://openalex.org/I4210096498']}, {'id': 'https://openalex.org/I2801107848', 'display_name': 'New York Hospital Queens', 'ror': 'https://ror.org/01j17xg39', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2801107848']}, {'id': 'https://openalex.org/I1340179700', 'display_name': 'NewYork–Presbyterian Hospital', 'ror': 'https://ror.org/03gzbrs57', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1340179700']}, {'id': 'https://openalex.org/I4387153466', 'display_name': 'Weill Cornell Medicine', 'ror': 'https://ror.org/02r109517', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I205783295', 'https://openalex.org/I4387153466']}, {'id': 'https://openalex.org/I205783295', 'display_name': 'Cornell University', 'ror': 'https://ror.org/05bnh6r87', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I205783295']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Gail J. Roboz', 'raw_affiliation_strings': ['Weill Cornell Medicine and New York Presbyterian Hospital, New York, NY;'], 'affiliations': [{'raw_affiliation_string': 'Weill Cornell Medicine and New York Presbyterian Hospital, New York, NY;', 'institution_ids': ['https://openalex.org/I4210096498', 'https://openalex.org/I2801107848', 'https://openalex.org/I1340179700', 'https://openalex.org/I4387153466', 'https://openalex.org/I205783295']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5014838075', 'display_name': 'Pierre Fenaux', 'orcid': 'https://orcid.org/0000-0002-0468-3553'}, 'institutions': [{'id': 'https://openalex.org/I4210144610', 'display_name': 'Hôpital Saint-Louis', 'ror': 'https://ror.org/049am9t04', 'country_code': 'FR', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210097159', 'https://openalex.org/I4210144610']}, {'id': 'https://openalex.org/I204730241', 'display_name': 'Université Paris Cité', 'ror': 'https://ror.org/05f82e368', 'country_code': 'FR', 'type': 'education', 'lineage': ['https://openalex.org/I204730241']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'Pierre Fenaux', 'raw_affiliation_strings': ['Section of Hematology, Saint-Louis Hospital, University Paris 7, Paris, France;'], 'affiliations': [{'raw_affiliation_string': 'Section of Hematology, Saint-Louis Hospital, University Paris 7, Paris, France;', 'institution_ids': ['https://openalex.org/I4210144610', 'https://openalex.org/I204730241']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5085360755', 'display_name': 'Mark R. Litzow', 'orcid': 'https://orcid.org/0000-0002-9816-6302'}, 'institutions': [{'id': 'https://openalex.org/I4210125099', 'display_name': 'Mayo Clinic in Arizona', 'ror': 'https://ror.org/03jp40720', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1330342723', 'https://openalex.org/I4210125099']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Mark R. Litzow', 'raw_affiliation_strings': ['Division of Hematology, Mayo Clinic, Rochester, MN;'], 'affiliations': [{'raw_affiliation_string': 'Division of Hematology, Mayo Clinic, Rochester, MN;', 'institution_ids': ['https://openalex.org/I4210125099']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5103074370', 'display_name': 'Sarah Perreault', 'orcid': 'https://orcid.org/0000-0002-4502-7579'}, 'institutions': [{'id': 'https://openalex.org/I1323778983', 'display_name': 'Yale New Haven Hospital', 'ror': 'https://ror.org/05tszed37', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1323778983', 'https://openalex.org/I4210117499']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Sarah Perreault', 'raw_affiliation_strings': ['Department of Pharmacy, Yale New Haven Hospital, New Haven, CT;'], 'affiliations': [{'raw_affiliation_string': 'Department of Pharmacy, Yale New Haven Hospital, New Haven, CT;', 'institution_ids': ['https://openalex.org/I1323778983']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5057178417', 'display_name': 'Tae Kon Kim', 'orcid': 'https://orcid.org/0000-0002-5182-3870'}, 'institutions': [{'id': 'https://openalex.org/I32971472', 'display_name': 'Yale University', 'ror': 'https://ror.org/03v76x132', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I32971472']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Tae Kon Kim', 'raw_affiliation_strings': ['Section of Hematology, Department of Internal Medicine, Yale University School of Medicine, New Haven, CT;'], 'affiliations': [{'raw_affiliation_string': 'Section of Hematology, Department of Internal Medicine, Yale University School of Medicine, New Haven, CT;', 'institution_ids': ['https://openalex.org/I32971472']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5035222674', 'display_name': 'Thomas Prébet', 'orcid': 'https://orcid.org/0000-0002-6872-625X'}, 'institutions': [{'id': 'https://openalex.org/I32971472', 'display_name': 'Yale University', 'ror': 'https://ror.org/03v76x132', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I32971472']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Thomas Prebet', 'raw_affiliation_strings': ['Section of Hematology, Department of Internal Medicine, Yale University School of Medicine, New Haven, CT;'], 'affiliations': [{'raw_affiliation_string': 'Section of Hematology, Department of Internal Medicine, Yale University School of Medicine, New Haven, CT;', 'institution_ids': ['https://openalex.org/I32971472']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5053724616', 'display_name': 'Norbert Vey', 'orcid': 'https://orcid.org/0000-0001-7027-040X'}, 'institutions': [{'id': 'https://openalex.org/I4210150365', 'display_name': 'Institut Paoli-Calmettes', 'ror': 'https://ror.org/04s3t1g37', 'country_code': 'FR', 'type': 'nonprofit', 'lineage': ['https://openalex.org/I4210150365']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'Norbert Vey', 'raw_affiliation_strings': ['Department of Hematology, Institut Paoli Calmettes, Marseille, France;'], 'affiliations': [{'raw_affiliation_string': 'Department of Hematology, Institut Paoli Calmettes, Marseille, France;', 'institution_ids': ['https://openalex.org/I4210150365']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5071827540', 'display_name': 'Vivek Verma', 'orcid': 'https://orcid.org/0000-0002-5863-6023'}, 'institutions': [{'id': 'https://openalex.org/I59130452', 'display_name': 'University of Nebraska Medical Center', 'ror': 'https://ror.org/00thqtb16', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I59130452']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Vivek Verma', 'raw_affiliation_strings': ['Division of Oncology & Hematology, University of Nebraska Medical Center, Omaha, NE;'], 'affiliations': [{'raw_affiliation_string': 'Division of Oncology & Hematology, University of Nebraska Medical Center, Omaha, NE;', 'institution_ids': ['https://openalex.org/I59130452']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5063615217', 'display_name': 'Ulrich Germing', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I44260953', 'display_name': 'Heinrich Heine University Düsseldorf', 'ror': 'https://ror.org/024z2rq82', 'country_code': 'DE', 'type': 'education', 'lineage': ['https://openalex.org/I44260953']}], 'countries': ['DE'], 'is_corresponding': False, 'raw_author_name': 'Ulrich Germing', 'raw_affiliation_strings': ['Department of Haematology, Oncology and Clinical Immunology, Heinrich-Heine University Duesseldorf, Duesseldorf, Germany;'], 'affiliations': [{'raw_affiliation_string': 'Department of Haematology, Oncology and Clinical Immunology, Heinrich-Heine University Duesseldorf, Duesseldorf, Germany;', 'institution_ids': ['https://openalex.org/I44260953']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5069030466', 'display_name': 'Juan Bergua', 'orcid': 'https://orcid.org/0000-0001-8229-1208'}, 'institutions': [{'id': 'https://openalex.org/I4210111317', 'display_name': 'Hospital San Pedro de Alcántara', 'ror': 'https://ror.org/01yp8kc21', 'country_code': 'ES', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210111317']}], 'countries': ['ES'], 'is_corresponding': False, 'raw_author_name': 'Juan Miguel Bergua', 'raw_affiliation_strings': ['Section of Hematology, Hospital San Pedro Alcántara, Cáceres, Spain; and'], 'affiliations': [{'raw_affiliation_string': 'Section of Hematology, Hospital San Pedro Alcántara, Cáceres, Spain; and', 'institution_ids': ['https://openalex.org/I4210111317']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5052872662', 'display_name': 'Josefina Serrano', 'orcid': 'https://orcid.org/0000-0003-1608-6016'}, 'institutions': [{'id': 'https://openalex.org/I4210123675', 'display_name': 'Hospital Universitario Reina Sofía', 'ror': 'https://ror.org/02vtd2q19', 'country_code': 'ES', 'type': 'healthcare', 'lineage': ['https://openalex.org/I158283456', 'https://openalex.org/I4210123675']}], 'countries': ['ES'], 'is_corresponding': False, 'raw_author_name': 'Josefina Serrano', 'raw_affiliation_strings': ['Section of Hematology, University Hospital Reina Sofia, Cordoba, Spain'], 'affiliations': [{'raw_affiliation_string': 'Section of Hematology, University Hospital Reina Sofia, Cordoba, Spain', 'institution_ids': ['https://openalex.org/I4210123675']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5101760493', 'display_name': 'Steven D. Gore', 'orcid': 'https://orcid.org/0000-0002-3649-8758'}, 'institutions': [{'id': 'https://openalex.org/I32971472', 'display_name': 'Yale University', 'ror': 'https://ror.org/03v76x132', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I32971472']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Steven D. Gore', 'raw_affiliation_strings': ['Section of Hematology, Department of Internal Medicine, Yale University School of Medicine, New Haven, CT;'], 'affiliations': [{'raw_affiliation_string': 'Section of Hematology, Department of Internal Medicine, Yale University School of Medicine, New Haven, CT;', 'institution_ids': ['https://openalex.org/I32971472']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5067521829', 'display_name': 'Amer M. Zeidan', 'orcid': 'https://orcid.org/0000-0001-7017-8160'}, 'institutions': [{'id': 'https://openalex.org/I32971472', 'display_name': 'Yale University', 'ror': 'https://ror.org/03v76x132', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I32971472']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Amer M. Zeidan', 'raw_affiliation_strings': ['Section of Hematology, Department of Internal Medicine, Yale University School of Medicine, New Haven, CT;'], 'affiliations': [{'raw_affiliation_string': 'Section of Hematology, Department of Internal Medicine, Yale University School of Medicine, New Haven, CT;', 'institution_ids': ['https://openalex.org/I32971472']}]}], 'institution_assertions': [], 'countries_distinct_count': 5, 'institutions_distinct_count': 24, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': {'value': 3000, 'currency': 'USD', 'value_usd': 3000, 'provenance': 'doaj'}, 'apc_paid': {'value': 3000, 'currency': 'USD', 'value_usd': 3000, 'provenance': 'doaj'}, 'fwci': 13.352, 'has_fulltext': False, 'cited_by_count': 129, 'citation_normalized_percentile': {'value': 0.99987, 'is_in_top_1_percent': True, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 98, 'max': 99}, 'biblio': {'volume': '2', 'issue': '8', 'first_page': '923', 'last_page': '932'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10309', 'display_name': 'Acute Myeloid Leukemia Research', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/2720', 'display_name': 'Hematology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10309', 'display_name': 'Acute Myeloid Leukemia Research', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/2720', 'display_name': 'Hematology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T11736', 'display_name': 'Histone Deacetylase Inhibitors Research', 'score': 0.9964, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T11628', 'display_name': 'Myeloproliferative Neoplasms: Diagnosis and Treatment', 'score': 0.9922, 'subfield': {'id': 'https://openalex.org/subfields/2716', 'display_name': 'Genetics'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/decitabine', 'display_name': 'Decitabine', 'score': 0.93503845}, {'id': 'https://openalex.org/keywords/azacitidine', 'display_name': 'Azacitidine', 'score': 0.8470845}, {'id': 'https://openalex.org/keywords/hypomethylating-agent', 'display_name': 'Hypomethylating agent', 'score': 0.7162576}, {'id': 'https://openalex.org/keywords/refractory', 'display_name': 'Refractory (planetary science)', 'score': 0.6485305}], 'concepts': [{'id': 'https://openalex.org/C2780235182', 'wikidata': 'https://www.wikidata.org/wiki/Q1181878', 'display_name': 'Decitabine', 'level': 5, 'score': 0.93503845}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.881576}, {'id': 'https://openalex.org/C2776239401', 'wikidata': 'https://www.wikidata.org/wiki/Q416451', 'display_name': 'Azacitidine', 'level': 5, 'score': 0.8470845}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.72956514}, {'id': 'https://openalex.org/C2776012956', 'wikidata': 'https://www.wikidata.org/wiki/Q17125294', 'display_name': 'Hypomethylating agent', 'level': 5, 'score': 0.7162576}, {'id': 'https://openalex.org/C142424586', 'wikidata': 'https://www.wikidata.org/wiki/Q7307572', 'display_name': 'Refractory (planetary science)', 'level': 2, 'score': 0.6485305}, {'id': 'https://openalex.org/C2778729363', 'wikidata': 'https://www.wikidata.org/wiki/Q11688946', 'display_name': 'Myeloid leukemia', 'level': 2, 'score': 0.57233787}, {'id': 'https://openalex.org/C44249647', 'wikidata': 'https://www.wikidata.org/wiki/Q208498', 'display_name': 'Confidence interval', 'level': 2, 'score': 0.5261811}, {'id': 'https://openalex.org/C2780240888', 'wikidata': 'https://www.wikidata.org/wiki/Q6052586', 'display_name': 'International Prognostic Scoring System', 'level': 4, 'score': 0.44483066}, {'id': 'https://openalex.org/C167135981', 'wikidata': 'https://www.wikidata.org/wiki/Q2146302', 'display_name': 'Retrospective cohort study', 'level': 2, 'score': 0.4395897}, {'id': 'https://openalex.org/C143998085', 'wikidata': 'https://www.wikidata.org/wiki/Q162555', 'display_name': 'Oncology', 'level': 1, 'score': 0.43725273}, {'id': 'https://openalex.org/C3018657049', 'wikidata': 'https://www.wikidata.org/wiki/Q1595418', 'display_name': 'Complete remission', 'level': 3, 'score': 0.4152633}, {'id': 'https://openalex.org/C2780007613', 'wikidata': 'https://www.wikidata.org/wiki/Q546523', 'display_name': 'Bone marrow', 'level': 2, 'score': 0.41148403}, {'id': 'https://openalex.org/C2780817109', 'wikidata': 'https://www.wikidata.org/wiki/Q954625', 'display_name': 'Myelodysplastic syndromes', 'level': 3, 'score': 0.3670866}, {'id': 'https://openalex.org/C2776694085', 'wikidata': 'https://www.wikidata.org/wiki/Q974135', 'display_name': 'Chemotherapy', 'level': 2, 'score': 0.27199113}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.0}, {'id': 'https://openalex.org/C150194340', 'wikidata': 'https://www.wikidata.org/wiki/Q26972', 'display_name': 'Gene expression', 'level': 3, 'score': 0.0}, {'id': 'https://openalex.org/C87355193', 'wikidata': 'https://www.wikidata.org/wiki/Q411', 'display_name': 'Astrobiology', 'level': 1, 'score': 0.0}, {'id': 'https://openalex.org/C190727270', 'wikidata': 'https://www.wikidata.org/wiki/Q874745', 'display_name': 'DNA methylation', 'level': 4, 'score': 0.0}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.0}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.0}, {'id': 'https://openalex.org/C121332964', 'wikidata': 'https://www.wikidata.org/wiki/Q413', 'display_name': 'Physics', 'level': 0, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D019175', 'descriptor_name': 'DNA Methylation', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': True}, {'descriptor_ui': 'D000077209', 'descriptor_name': 'Decitabine', 'qualifier_ui': 'Q000627', 'qualifier_name': 'therapeutic use', 'is_major_topic': True}, {'descriptor_ui': 'D015470', 'descriptor_name': 'Leukemia, Myeloid, Acute', 'qualifier_ui': 'Q000188', 'qualifier_name': 'drug therapy', 'is_major_topic': True}, {'descriptor_ui': 'D016879', 'descriptor_name': 'Salvage Therapy', 'qualifier_ui': 'Q000379', 'qualifier_name': 'methods', 'is_major_topic': True}, {'descriptor_ui': 'D000293', 'descriptor_name': 'Adolescent', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000328', 'descriptor_name': 'Adult', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000368', 'descriptor_name': 'Aged', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000369', 'descriptor_name': 'Aged, 80 and over', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000964', 'descriptor_name': 'Antimetabolites, Antineoplastic', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000964', 'descriptor_name': 'Antimetabolites, Antineoplastic', 'qualifier_ui': 'Q000627', 'qualifier_name': 'therapeutic use', 'is_major_topic': False}, {'descriptor_ui': 'D015331', 'descriptor_name': 'Cohort Studies', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D019175', 'descriptor_name': 'DNA Methylation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D016208', 'descriptor_name': 'Databases, Factual', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000077209', 'descriptor_name': 'Decitabine', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015470', 'descriptor_name': 'Leukemia, Myeloid, Acute', 'qualifier_ui': 'Q000401', 'qualifier_name': 'mortality', 'is_major_topic': False}, {'descriptor_ui': 'D015470', 'descriptor_name': 'Leukemia, Myeloid, Acute', 'qualifier_ui': 'Q000175', 'qualifier_name': 'diagnosis', 'is_major_topic': False}, {'descriptor_ui': 'D015470', 'descriptor_name': 'Leukemia, Myeloid, Acute', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015470', 'descriptor_name': 'Leukemia, Myeloid, Acute', 'qualifier_ui': 'Q000473', 'qualifier_name': 'pathology', 'is_major_topic': False}, {'descriptor_ui': 'D008875', 'descriptor_name': 'Middle Aged', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011379', 'descriptor_name': 'Prognosis', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D012074', 'descriptor_name': 'Remission Induction', 'qualifier_ui': 'Q000379', 'qualifier_name': 'methods', 'is_major_topic': False}, {'descriptor_ui': 'D012074', 'descriptor_name': 'Remission Induction', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D012189', 'descriptor_name': 'Retrospective Studies', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D016879', 'descriptor_name': 'Salvage Therapy', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D016019', 'descriptor_name': 'Survival Analysis', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D016896', 'descriptor_name': 'Treatment Outcome', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D055815', 'descriptor_name': 'Young Adult', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 5, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.1182/bloodadvances.2018016121', 'pdf_url': 'https://ashpublications.org/bloodadvances/article-pdf/2/8/923/880924/advances016121.pdf', 'source': {'id': 'https://openalex.org/S2764683450', 'display_name': 'Blood Advances', 'issn_l': '2473-9529', 'issn': ['2473-9529', '2473-9537'], 'is_oa': True, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': 'cc-by-nc-nd', 'license_id': 'https://openalex.org/licenses/cc-by-nc-nd', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://hdl.handle.net/2158/1175141', 'pdf_url': 'https://flore.unifi.it/bitstream/2158/1175141/2/advances016121_HMA%20AML.pdf', 'source': {'id': 'https://openalex.org/S4306402033', 'display_name': 'Florence Research (University of Florence)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I45084792', 'host_organization_name': 'University of Florence', 'host_organization_lineage': ['https://openalex.org/I45084792'], 'host_organization_lineage_names': ['University of Florence'], 'type': 'repository'}, 'license': 'other-oa', 'license_id': 'https://openalex.org/licenses/other-oa', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://europepmc.org/articles/pmc5916007', 'pdf_url': 'https://europepmc.org/articles/pmc5916007?pdf=render', 'source': {'id': 'https://openalex.org/S4306400806', 'display_name': 'Europe PMC (PubMed Central)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1303153112', 'host_organization_name': 'European Bioinformatics Institute', 'host_organization_lineage': ['https://openalex.org/I1303153112'], 'host_organization_lineage_names': ['European Bioinformatics Institute'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5916007', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/29685952', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1182/bloodadvances.2018016121', 'pdf_url': 'https://ashpublications.org/bloodadvances/article-pdf/2/8/923/880924/advances016121.pdf', 'source': {'id': 'https://openalex.org/S2764683450', 'display_name': 'Blood Advances', 'issn_l': '2473-9529', 'issn': ['2473-9529', '2473-9537'], 'is_oa': True, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': 'cc-by-nc-nd', 'license_id': 'https://openalex.org/licenses/cc-by-nc-nd', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 36, 'referenced_works': ['https://openalex.org/W1572539757', 'https://openalex.org/W1600365609', 'https://openalex.org/W1764888106', 'https://openalex.org/W1973392550', 'https://openalex.org/W1981886750', 'https://openalex.org/W1982035148', 'https://openalex.org/W1996917824', 'https://openalex.org/W2015776863', 'https://openalex.org/W2044088883', 'https://openalex.org/W2058794589', 'https://openalex.org/W2068556430', 'https://openalex.org/W2081391009', 'https://openalex.org/W2082365047', 'https://openalex.org/W2087387748', 'https://openalex.org/W2095588623', 'https://openalex.org/W2097035477', 'https://openalex.org/W2104222465', 'https://openalex.org/W2110893339', 'https://openalex.org/W2111064444', 'https://openalex.org/W2115098571', 'https://openalex.org/W2116858301', 'https://openalex.org/W2117446917', 'https://openalex.org/W2121603250', 'https://openalex.org/W2129510594', 'https://openalex.org/W2144395887', 'https://openalex.org/W2147083172', 'https://openalex.org/W2150480709', 'https://openalex.org/W2159507916', 'https://openalex.org/W2159746057', 'https://openalex.org/W2517675534', 'https://openalex.org/W2530673457', 'https://openalex.org/W2549790759', 'https://openalex.org/W2556473631', 'https://openalex.org/W2623089849', 'https://openalex.org/W2654449699', 'https://openalex.org/W4298826872'], 'related_works': ['https://openalex.org/W4245640489', 'https://openalex.org/W3203236595', 'https://openalex.org/W2559444916', 'https://openalex.org/W2557741488', 'https://openalex.org/W2436188093', 'https://openalex.org/W2409251897', 'https://openalex.org/W2096084875', 'https://openalex.org/W2054507167', 'https://openalex.org/W2051650123', 'https://openalex.org/W1983754555'], 'abstract_inverted_index': {'Although': [0], 'hypomethylating': [1], 'agents': [2], '(HMAs)': [3], 'are': [4], 'frequently': [5], 'used': [6], 'in': [7, 24, 42], 'the': [8, 38, 142, 161], 'frontline': [9], 'treatment': [10], 'of': [11, 40, 48, 56, 133, 144, 152, 163, 180, 193, 197], 'older': [12], 'acute': [13], 'myeloid': [14], 'leukemia': [15], '(AML)': [16], 'patients,': [17], 'little': [18], 'is': [19], 'known': [20], 'about': [21], 'their': [22], 'effectiveness': [23, 39], 'relapsed': [25, 74], 'or': [26, 65, 93], 'primary': [27], 'treatment-refractory': [28], '(RR)-AML.': [29], 'Using': [30], 'an': [31], 'international': [32], 'multicenter': [33], 'retrospective': [34], 'database,': [35], 'we': [36], 'studied': [37], 'HMAs': [41, 87, 187, 201], 'RR-AML': [43, 181], 'and': [44, 50, 72, 127, 135, 148, 167, 188], 'evaluated': [45], 'for': [46, 207], 'predictors': [47], 'response': [49, 85, 158], 'overall': [51], 'survival': [52], '(OS).': [53], 'A': [54, 177], 'total': [55], '655': [57], 'patients': [58, 124, 182, 209], 'from': [59], '12': [60], 'centers': [61], 'received': [62], 'azacitidine': [63], '(57%)': [64], 'decitabine': [66, 153], '(43%),': [67], 'including': [68], '290': [69], 'refractory': [70], '(44%)': [71], '365': [73], '(56%)': [75], 'patients.': [76], 'Median': [77, 106], 'age': [78], 'at': [79], 'diagnosis': [80], 'was': [81, 88, 108], '65': [82], 'years.': [83], 'Best': [84], 'to': [86], 'complete': [89], 'remission': [90], '(CR;': [91], '11%)': [92], 'CR': [94, 126], 'with': [95, 123, 156, 174, 186, 210], 'incomplete': [96], 'count': [97], 'recovery': [98], '(CRi;': [99], '5.3%).': [100], 'Additionally,': [101], '8.5%': [102], 'experienced': [103, 189], 'hematologic': [104], 'improvement.': [105], 'OS': [107, 117, 132, 192], '6.7': [109], 'months': [110], '(95%': [111], 'confidence': [112], 'interval,': [113], '6.1-7.3).': [114], 'As': [115], 'expected,': [116], 'differed': [118], 'significantly': [119], 'by': [120], 'best': [121], 'response,': [122], 'achieving': [125], 'CRi': [128], 'having': [129], 'a': [130, 149, 190, 198, 203], 'median': [131, 191], '25.3': [134], '14.6': [136], 'months,': [137], 'respectively.': [138], 'In': [139], 'multivariate': [140], 'analysis,': [141], 'presence': [143, 162], '≤5%': [145], 'circulating': [146, 165], 'blasts': [147, 166, 171], '10-day': [150], 'schedule': [151], 'were': [154, 172], 'associated': [155, 173], 'improved': [157], 'rates,': [159], 'whereas': [160], '>5%': [164], '>20%': [168], 'bone': [169], 'marrow': [170], 'decreased': [175], 'OS.': [176], 'significant': [178], 'subset': [179], '(16%)': [183], 'achieved': [184], 'CR/CRi': [185], '21': [194], 'months.': [195], 'Outside': [196], 'clinical': [199], 'trial,': [200], 'represent': [202], 'reasonable': [204], 'therapeutic': [205], 'option': [206], 'some': [208], 'RR-AML.': [211]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2800327377', 'counts_by_year': [{'year': 2024, 'cited_by_count': 10}, {'year': 2023, 'cited_by_count': 19}, {'year': 2022, 'cited_by_count': 26}, {'year': 2021, 'cited_by_count': 24}, {'year': 2020, 'cited_by_count': 20}, {'year': 2019, 'cited_by_count': 21}, {'year': 2018, 'cited_by_count': 7}], 'updated_date': '2024-12-24T15:59:18.360392', 'created_date': '2018-05-17'}