Efficacy of the combination of venetoclax and hypomethylating agents in relapsed/refractory acute myeloid leukemia

Name: Work Video:
Duration: 3 min 30 s
Ibrahim Aldoss; Dongyun Yang; Ahmed Aribi; Haris Ali; Karamjeet S. Sandhu; Monzr M. Al Malki; Matthew Mei; Amandeep Salhotra; Samer K. Khaled; Ryotaro Nakamura; David S. Snyder; Margaret O’Donnell; Anthony S. Stein; Stephen J. Forman; Guido Marcucci; Vinod Pullarkat
{'id': 'https://openalex.org/W2793886497', 'doi': 'https://doi.org/10.3324/haematol.2018.188094', 'title': 'Efficacy of the combination of venetoclax and hypomethylating agents in relapsed/refractory acute myeloid leukemia', 'display_name': 'Efficacy of the combination of venetoclax and hypomethylating agents in relapsed/refractory acute myeloid leukemia', 'publication_year': 2018, 'publication_date': '2018-03-15', 'ids': {'openalex': 'https://openalex.org/W2793886497', 'doi': 'https://doi.org/10.3324/haematol.2018.188094', 'mag': '2793886497', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/29545346', 'pmcid': 'https://www.ncbi.nlm.nih.gov/pmc/articles/6119155'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.3324/haematol.2018.188094', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2752781272', 'display_name': 'Haematologica', 'issn_l': '0390-6078', 'issn': ['0390-6078', '1592-8721'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310317774', 'host_organization_name': 'Ferrata Storti Foundation', 'host_organization_lineage': ['https://openalex.org/P4310317774'], 'host_organization_lineage_names': ['Ferrata Storti Foundation'], 'type': 'journal'}, 'license': 'cc-by-nc', 'license_id': 'https://openalex.org/licenses/cc-by-nc', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'letter', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'gold', 'oa_url': 'https://doi.org/10.3324/haematol.2018.188094', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5040369089', 'display_name': 'Ibrahim Aldoss', 'orcid': 'https://orcid.org/0000-0001-9564-4498'}, 'institutions': [{'id': 'https://openalex.org/I4210110459', 'display_name': 'City of Hope', 'ror': 'https://ror.org/01z1vct10', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1301076528', 'https://openalex.org/I4210110459']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Ibrahim Aldoss', 'raw_affiliation_strings': ['Department of Hematology and Hematopoietic Cell Transplantation, Gehr Family Center for Leukemia Research, City of Hope, Duarte, CA, USA'], 'affiliations': [{'raw_affiliation_string': 'Department of Hematology and Hematopoietic Cell Transplantation, Gehr Family Center for Leukemia Research, City of Hope, Duarte, CA, USA', 'institution_ids': ['https://openalex.org/I4210110459']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5090001130', 'display_name': 'Dongyun Yang', 'orcid': 'https://orcid.org/0000-0003-0736-4977'}, 'institutions': [{'id': 'https://openalex.org/I4210110459', 'display_name': 'City of Hope', 'ror': 'https://ror.org/01z1vct10', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1301076528', 'https://openalex.org/I4210110459']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Dongyun Yang', 'raw_affiliation_strings': ['Department of Information Sciences, Division of Biostatistics, City of Hope, Duarte, CA, USA'], 'affiliations': [{'raw_affiliation_string': 'Department of Information Sciences, Division of Biostatistics, City of Hope, Duarte, CA, USA', 'institution_ids': ['https://openalex.org/I4210110459']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5038541414', 'display_name': 'Ahmed Aribi', 'orcid': 'https://orcid.org/0000-0003-2497-3176'}, 'institutions': [{'id': 'https://openalex.org/I4210110459', 'display_name': 'City of Hope', 'ror': 'https://ror.org/01z1vct10', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1301076528', 'https://openalex.org/I4210110459']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Ahmed Aribi', 'raw_affiliation_strings': ['Department of Hematology and Hematopoietic Cell Transplantation, Gehr Family Center for Leukemia Research, City of Hope, Duarte, CA, USA'], 'affiliations': [{'raw_affiliation_string': 'Department of Hematology and Hematopoietic Cell Transplantation, Gehr Family Center for Leukemia Research, City of Hope, Duarte, CA, USA', 'institution_ids': ['https://openalex.org/I4210110459']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5070193149', 'display_name': 'Haris Ali', 'orcid': 'https://orcid.org/0000-0002-9728-7292'}, 'institutions': [{'id': 'https://openalex.org/I4210110459', 'display_name': 'City of Hope', 'ror': 'https://ror.org/01z1vct10', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1301076528', 'https://openalex.org/I4210110459']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Haris Ali', 'raw_affiliation_strings': ['Department of Hematology and Hematopoietic Cell Transplantation, Gehr Family Center for Leukemia Research, City of Hope, Duarte, CA, USA'], 'affiliations': [{'raw_affiliation_string': 'Department of Hematology and Hematopoietic Cell Transplantation, Gehr Family Center for Leukemia Research, City of Hope, Duarte, CA, USA', 'institution_ids': ['https://openalex.org/I4210110459']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5063345064', 'display_name': 'Karamjeet S. Sandhu', 'orcid': 'https://orcid.org/0000-0001-8024-8484'}, 'institutions': [{'id': 'https://openalex.org/I4210110459', 'display_name': 'City of Hope', 'ror': 'https://ror.org/01z1vct10', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1301076528', 'https://openalex.org/I4210110459']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Karamjeet Sandhu', 'raw_affiliation_strings': ['Department of Hematology and Hematopoietic Cell Transplantation, Gehr Family Center for Leukemia Research, City of Hope, Duarte, CA, USA'], 'affiliations': [{'raw_affiliation_string': 'Department of Hematology and Hematopoietic Cell Transplantation, Gehr Family Center for Leukemia Research, City of Hope, Duarte, CA, USA', 'institution_ids': ['https://openalex.org/I4210110459']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5048360588', 'display_name': 'Monzr M. Al Malki', 'orcid': 'https://orcid.org/0000-0001-8226-471X'}, 'institutions': [{'id': 'https://openalex.org/I4210110459', 'display_name': 'City of Hope', 'ror': 'https://ror.org/01z1vct10', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1301076528', 'https://openalex.org/I4210110459']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Monzr M. Al Malki', 'raw_affiliation_strings': ['Department of Hematology and Hematopoietic Cell Transplantation, Gehr Family Center for Leukemia Research, City of Hope, Duarte, CA, USA'], 'affiliations': [{'raw_affiliation_string': 'Department of Hematology and Hematopoietic Cell Transplantation, Gehr Family Center for Leukemia Research, City of Hope, Duarte, CA, USA', 'institution_ids': ['https://openalex.org/I4210110459']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5063781871', 'display_name': 'Matthew Mei', 'orcid': 'https://orcid.org/0000-0002-1109-6955'}, 'institutions': [{'id': 'https://openalex.org/I4210110459', 'display_name': 'City of Hope', 'ror': 'https://ror.org/01z1vct10', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1301076528', 'https://openalex.org/I4210110459']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Matthew Mei', 'raw_affiliation_strings': ['Department of Hematology and Hematopoietic Cell Transplantation, Gehr Family Center for Leukemia Research, City of Hope, Duarte, CA, USA'], 'affiliations': [{'raw_affiliation_string': 'Department of Hematology and Hematopoietic Cell Transplantation, Gehr Family Center for Leukemia Research, City of Hope, Duarte, CA, USA', 'institution_ids': ['https://openalex.org/I4210110459']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5065052780', 'display_name': 'Amandeep Salhotra', 'orcid': 'https://orcid.org/0000-0002-9302-5041'}, 'institutions': [{'id': 'https://openalex.org/I4210110459', 'display_name': 'City of Hope', 'ror': 'https://ror.org/01z1vct10', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1301076528', 'https://openalex.org/I4210110459']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Amandeep Salhotra', 'raw_affiliation_strings': ['Department of Hematology and Hematopoietic Cell Transplantation, Gehr Family Center for Leukemia Research, City of Hope, Duarte, CA, USA'], 'affiliations': [{'raw_affiliation_string': 'Department of Hematology and Hematopoietic Cell Transplantation, Gehr Family Center for Leukemia Research, City of Hope, Duarte, CA, USA', 'institution_ids': ['https://openalex.org/I4210110459']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5087735259', 'display_name': 'Samer K. Khaled', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210110459', 'display_name': 'City of Hope', 'ror': 'https://ror.org/01z1vct10', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1301076528', 'https://openalex.org/I4210110459']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Samer Khaled', 'raw_affiliation_strings': ['Department of Hematology and Hematopoietic Cell Transplantation, Gehr Family Center for Leukemia Research, City of Hope, Duarte, CA, USA'], 'affiliations': [{'raw_affiliation_string': 'Department of Hematology and Hematopoietic Cell Transplantation, Gehr Family Center for Leukemia Research, City of Hope, Duarte, CA, USA', 'institution_ids': ['https://openalex.org/I4210110459']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5086494836', 'display_name': 'Ryotaro Nakamura', 'orcid': 'https://orcid.org/0000-0002-9082-0680'}, 'institutions': [{'id': 'https://openalex.org/I4210110459', 'display_name': 'City of Hope', 'ror': 'https://ror.org/01z1vct10', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1301076528', 'https://openalex.org/I4210110459']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Ryotaro Nakamura', 'raw_affiliation_strings': ['Department of Hematology and Hematopoietic Cell Transplantation, Gehr Family Center for Leukemia Research, City of Hope, Duarte, CA, USA'], 'affiliations': [{'raw_affiliation_string': 'Department of Hematology and Hematopoietic Cell Transplantation, Gehr Family Center for Leukemia Research, City of Hope, Duarte, CA, USA', 'institution_ids': ['https://openalex.org/I4210110459']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5113550483', 'display_name': 'David S. Snyder', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210110459', 'display_name': 'City of Hope', 'ror': 'https://ror.org/01z1vct10', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1301076528', 'https://openalex.org/I4210110459']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'David Snyder', 'raw_affiliation_strings': ['Department of Hematology and Hematopoietic Cell Transplantation, Gehr Family Center for Leukemia Research, City of Hope, Duarte, CA, USA'], 'affiliations': [{'raw_affiliation_string': 'Department of Hematology and Hematopoietic Cell Transplantation, Gehr Family Center for Leukemia Research, City of Hope, Duarte, CA, USA', 'institution_ids': ['https://openalex.org/I4210110459']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5109911056', 'display_name': 'Margaret O’Donnell', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210110459', 'display_name': 'City of Hope', 'ror': 'https://ror.org/01z1vct10', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1301076528', 'https://openalex.org/I4210110459']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Margaret O’Donnell', 'raw_affiliation_strings': ['Department of Hematology and Hematopoietic Cell Transplantation, Gehr Family Center for Leukemia Research, City of Hope, Duarte, CA, USA'], 'affiliations': [{'raw_affiliation_string': 'Department of Hematology and Hematopoietic Cell Transplantation, Gehr Family Center for Leukemia Research, City of Hope, Duarte, CA, USA', 'institution_ids': ['https://openalex.org/I4210110459']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5020684790', 'display_name': 'Anthony S. Stein', 'orcid': 'https://orcid.org/0000-0002-1786-1398'}, 'institutions': [{'id': 'https://openalex.org/I4210110459', 'display_name': 'City of Hope', 'ror': 'https://ror.org/01z1vct10', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1301076528', 'https://openalex.org/I4210110459']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Anthony S. Stein', 'raw_affiliation_strings': ['Department of Hematology and Hematopoietic Cell Transplantation, Gehr Family Center for Leukemia Research, City of Hope, Duarte, CA, USA'], 'affiliations': [{'raw_affiliation_string': 'Department of Hematology and Hematopoietic Cell Transplantation, Gehr Family Center for Leukemia Research, City of Hope, Duarte, CA, USA', 'institution_ids': ['https://openalex.org/I4210110459']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5039374832', 'display_name': 'Stephen J. Forman', 'orcid': 'https://orcid.org/0000-0002-2803-4152'}, 'institutions': [{'id': 'https://openalex.org/I4210110459', 'display_name': 'City of Hope', 'ror': 'https://ror.org/01z1vct10', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1301076528', 'https://openalex.org/I4210110459']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Stephen J. Forman', 'raw_affiliation_strings': ['Department of Hematology and Hematopoietic Cell Transplantation, Gehr Family Center for Leukemia Research, City of Hope, Duarte, CA, USA'], 'affiliations': [{'raw_affiliation_string': 'Department of Hematology and Hematopoietic Cell Transplantation, Gehr Family Center for Leukemia Research, City of Hope, Duarte, CA, USA', 'institution_ids': ['https://openalex.org/I4210110459']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5060959458', 'display_name': 'Guido Marcucci', 'orcid': 'https://orcid.org/0000-0002-3983-5908'}, 'institutions': [{'id': 'https://openalex.org/I4210110459', 'display_name': 'City of Hope', 'ror': 'https://ror.org/01z1vct10', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1301076528', 'https://openalex.org/I4210110459']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Guido Marcucci', 'raw_affiliation_strings': ['Department of Hematology and Hematopoietic Cell Transplantation, Gehr Family Center for Leukemia Research, City of Hope, Duarte, CA, USA'], 'affiliations': [{'raw_affiliation_string': 'Department of Hematology and Hematopoietic Cell Transplantation, Gehr Family Center for Leukemia Research, City of Hope, Duarte, CA, USA', 'institution_ids': ['https://openalex.org/I4210110459']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5024492683', 'display_name': 'Vinod Pullarkat', 'orcid': 'https://orcid.org/0000-0001-9129-3424'}, 'institutions': [{'id': 'https://openalex.org/I4210110459', 'display_name': 'City of Hope', 'ror': 'https://ror.org/01z1vct10', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1301076528', 'https://openalex.org/I4210110459']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Vinod Pullarkat', 'raw_affiliation_strings': ['Department of Hematology and Hematopoietic Cell Transplantation, Gehr Family Center for Leukemia Research, City of Hope, Duarte, CA, USA'], 'affiliations': [{'raw_affiliation_string': 'Department of Hematology and Hematopoietic Cell Transplantation, Gehr Family Center for Leukemia Research, City of Hope, Duarte, CA, USA', 'institution_ids': ['https://openalex.org/I4210110459']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 1, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': {'value': 2000, 'currency': 'EUR', 'value_usd': 2157, 'provenance': 'doaj'}, 'apc_paid': {'value': 2000, 'currency': 'EUR', 'value_usd': 2157, 'provenance': 'doaj'}, 'fwci': None, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 225, 'citation_normalized_percentile': {'value': 0.99775, 'is_in_top_1_percent': True, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 99, 'max': 100}, 'biblio': {'volume': '103', 'issue': '9', 'first_page': 'e404', 'last_page': 'e407'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10309', 'display_name': 'Acute Myeloid Leukemia Research', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/2720', 'display_name': 'Hematology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10309', 'display_name': 'Acute Myeloid Leukemia Research', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/2720', 'display_name': 'Hematology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T11215', 'display_name': 'Chronic Myeloid Leukemia Treatments', 'score': 0.9948, 'subfield': {'id': 'https://openalex.org/subfields/2720', 'display_name': 'Hematology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T11628', 'display_name': 'Myeloproliferative Neoplasms: Diagnosis and Treatment', 'score': 0.9941, 'subfield': {'id': 'https://openalex.org/subfields/2716', 'display_name': 'Genetics'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/venetoclax', 'display_name': 'Venetoclax', 'score': 0.9245676}, {'id': 'https://openalex.org/keywords/hypomethylating-agent', 'display_name': 'Hypomethylating agent', 'score': 0.7926059}, {'id': 'https://openalex.org/keywords/azacitidine', 'display_name': 'Azacitidine', 'score': 0.64527965}, {'id': 'https://openalex.org/keywords/refractory', 'display_name': 'Refractory (planetary science)', 'score': 0.55878955}], 'concepts': [{'id': 'https://openalex.org/C2779675984', 'wikidata': 'https://www.wikidata.org/wiki/Q23671272', 'display_name': 'Venetoclax', 'level': 4, 'score': 0.9245676}, {'id': 'https://openalex.org/C2776012956', 'wikidata': 'https://www.wikidata.org/wiki/Q17125294', 'display_name': 'Hypomethylating agent', 'level': 5, 'score': 0.7926059}, {'id': 'https://openalex.org/C2778729363', 'wikidata': 'https://www.wikidata.org/wiki/Q11688946', 'display_name': 'Myeloid leukemia', 'level': 2, 'score': 0.7565942}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.7129638}, {'id': 'https://openalex.org/C2776239401', 'wikidata': 'https://www.wikidata.org/wiki/Q416451', 'display_name': 'Azacitidine', 'level': 5, 'score': 0.64527965}, {'id': 'https://openalex.org/C142424586', 'wikidata': 'https://www.wikidata.org/wiki/Q7307572', 'display_name': 'Refractory (planetary science)', 'level': 2, 'score': 0.55878955}, {'id': 'https://openalex.org/C2778461978', 'wikidata': 'https://www.wikidata.org/wiki/Q29496', 'display_name': 'Leukemia', 'level': 2, 'score': 0.4678225}, {'id': 'https://openalex.org/C143998085', 'wikidata': 'https://www.wikidata.org/wiki/Q162555', 'display_name': 'Oncology', 'level': 1, 'score': 0.44218153}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.38659066}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.09013146}, {'id': 'https://openalex.org/C190727270', 'wikidata': 'https://www.wikidata.org/wiki/Q874745', 'display_name': 'DNA methylation', 'level': 4, 'score': 0.06821871}, {'id': 'https://openalex.org/C150194340', 'wikidata': 'https://www.wikidata.org/wiki/Q26972', 'display_name': 'Gene expression', 'level': 3, 'score': 0.0}, {'id': 'https://openalex.org/C2777938653', 'wikidata': 'https://www.wikidata.org/wiki/Q1088156', 'display_name': 'Chronic lymphocytic leukemia', 'level': 3, 'score': 0.0}, {'id': 'https://openalex.org/C87355193', 'wikidata': 'https://www.wikidata.org/wiki/Q411', 'display_name': 'Astrobiology', 'level': 1, 'score': 0.0}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.0}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D015470', 'descriptor_name': 'Leukemia, Myeloid, Acute', 'qualifier_ui': 'Q000188', 'qualifier_name': 'drug therapy', 'is_major_topic': True}, {'descriptor_ui': 'D000971', 'descriptor_name': 'Antineoplastic Combined Chemotherapy Protocols', 'qualifier_ui': 'Q000009', 'qualifier_name': 'adverse effects', 'is_major_topic': False}, {'descriptor_ui': 'D019086', 'descriptor_name': 'Bridged Bicyclo Compounds, Heterocyclic', 'qualifier_ui': 'Q000008', 'qualifier_name': 'administration & dosage', 'is_major_topic': False}, {'descriptor_ui': 'D000077209', 'descriptor_name': 'Decitabine', 'qualifier_ui': 'Q000008', 'qualifier_name': 'administration & dosage', 'is_major_topic': False}, {'descriptor_ui': 'D019008', 'descriptor_name': 'Drug Resistance, Neoplasm', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D012008', 'descriptor_name': 'Recurrence', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D019233', 'descriptor_name': 'Retreatment', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013449', 'descriptor_name': 'Sulfonamides', 'qualifier_ui': 'Q000008', 'qualifier_name': 'administration & dosage', 'is_major_topic': False}, {'descriptor_ui': 'D016019', 'descriptor_name': 'Survival Analysis', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D016896', 'descriptor_name': 'Treatment Outcome', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 4, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.3324/haematol.2018.188094', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2752781272', 'display_name': 'Haematologica', 'issn_l': '0390-6078', 'issn': ['0390-6078', '1592-8721'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310317774', 'host_organization_name': 'Ferrata Storti Foundation', 'host_organization_lineage': ['https://openalex.org/P4310317774'], 'host_organization_lineage_names': ['Ferrata Storti Foundation'], 'type': 'journal'}, 'license': 'cc-by-nc', 'license_id': 'https://openalex.org/licenses/cc-by-nc', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://europepmc.org/articles/pmc6119155', 'pdf_url': 'https://europepmc.org/articles/pmc6119155?pdf=render', 'source': {'id': 'https://openalex.org/S4306400806', 'display_name': 'Europe PMC (PubMed Central)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1303153112', 'host_organization_name': 'European Bioinformatics Institute', 'host_organization_lineage': ['https://openalex.org/I1303153112'], 'host_organization_lineage_names': ['European Bioinformatics Institute'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6119155', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/29545346', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.3324/haematol.2018.188094', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2752781272', 'display_name': 'Haematologica', 'issn_l': '0390-6078', 'issn': ['0390-6078', '1592-8721'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310317774', 'host_organization_name': 'Ferrata Storti Foundation', 'host_organization_lineage': ['https://openalex.org/P4310317774'], 'host_organization_lineage_names': ['Ferrata Storti Foundation'], 'type': 'journal'}, 'license': 'cc-by-nc', 'license_id': 'https://openalex.org/licenses/cc-by-nc', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 12, 'referenced_works': ['https://openalex.org/W1600365609', 'https://openalex.org/W2047122678', 'https://openalex.org/W2087387748', 'https://openalex.org/W2089532685', 'https://openalex.org/W2147083172', 'https://openalex.org/W2157287007', 'https://openalex.org/W2159507916', 'https://openalex.org/W2192121806', 'https://openalex.org/W2517675534', 'https://openalex.org/W2559537906', 'https://openalex.org/W2761234508', 'https://openalex.org/W2898284215'], 'related_works': ['https://openalex.org/W4405051588', 'https://openalex.org/W4401878169', 'https://openalex.org/W4401875674', 'https://openalex.org/W4388673960', 'https://openalex.org/W4362592484', 'https://openalex.org/W4362542584', 'https://openalex.org/W4310159665', 'https://openalex.org/W3131716652', 'https://openalex.org/W3048827006', 'https://openalex.org/W2899412336'], 'abstract_inverted_index': None, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2793886497', 'counts_by_year': [{'year': 2024, 'cited_by_count': 28}, {'year': 2023, 'cited_by_count': 33}, {'year': 2022, 'cited_by_count': 49}, {'year': 2021, 'cited_by_count': 40}, {'year': 2020, 'cited_by_count': 44}, {'year': 2019, 'cited_by_count': 26}, {'year': 2018, 'cited_by_count': 4}], 'updated_date': '2024-12-24T09:05:05.718217', 'created_date': '2018-03-29'}
Publication Information

Basic Information

Access and Citation

AI Researcher Chatbot

Primary Location

Authors

Topics

Keywords

Related Works
