Publication Information

{'id': 'https://openalex.org/W2789887784', 'doi': 'https://doi.org/10.1111/jfbc.12518', 'title': 'Evaluation of the antidiabetic activity of hydrolyzed peptides derived from<i>Juglans mandshurica</i>Maxim. fruits in insulin-resistant HepG2 cells and type 2 diabetic mice', 'display_name': 'Evaluation of the antidiabetic activity of hydrolyzed peptides derived from<i>Juglans mandshurica</i>Maxim. fruits in insulin-resistant HepG2 cells and type 2 diabetic mice', 'publication_year': 2018, 'publication_date': '2018-02-21', 'ids': {'openalex': 'https://openalex.org/W2789887784', 'doi': 'https://doi.org/10.1111/jfbc.12518', 'mag': '2789887784'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1111/jfbc.12518', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S53703007', 'display_name': 'Journal of Food Biochemistry', 'issn_l': '0145-8884', 'issn': ['0145-8884', '1745-4514'], 'is_oa': True, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320595', 'host_organization_name': 'Wiley', 'host_organization_lineage': ['https://openalex.org/P4310320595'], 'host_organization_lineage_names': ['Wiley'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref'], 'open_access': {'is_oa': True, 'oa_status': 'gold', 'oa_url': 'https://doi.org/10.1111/jfbc.12518', 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5100621951', 'display_name': 'Ji Wang', 'orcid': 'https://orcid.org/0000-0001-5042-2541'}, 'institutions': [{'id': 'https://openalex.org/I4210152006', 'display_name': 'Jilin Agricultural University', 'ror': 'https://ror.org/05dmhhd41', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I4210152006']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Ji Wang', 'raw_affiliation_strings': ["College of Food Science and Engineering, Jilin Agricultural University, Changchun, 130118 People's Republic of China", "National Engineering Laboratory on Wheat and Corn Further Processing, Changchun, JiLin, 130118 People's Republic of China"], 'affiliations': [{'raw_affiliation_string': "College of Food Science and Engineering, Jilin Agricultural University, Changchun, 130118 People's Republic of China", 'institution_ids': ['https://openalex.org/I4210152006']}, {'raw_affiliation_string': "National Engineering Laboratory on Wheat and Corn Further Processing, Changchun, JiLin, 130118 People's Republic of China", 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5028069837', 'display_name': 'Kaiying Du', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210152006', 'display_name': 'Jilin Agricultural University', 'ror': 'https://ror.org/05dmhhd41', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I4210152006']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Kaiying Du', 'raw_affiliation_strings': ["College of Food Science and Engineering, Jilin Agricultural University, Changchun, 130118 People's Republic of China", "National Engineering Laboratory on Wheat and Corn Further Processing, Changchun, JiLin, 130118 People's Republic of China"], 'affiliations': [{'raw_affiliation_string': "College of Food Science and Engineering, Jilin Agricultural University, Changchun, 130118 People's Republic of China", 'institution_ids': ['https://openalex.org/I4210152006']}, {'raw_affiliation_string': "National Engineering Laboratory on Wheat and Corn Further Processing, Changchun, JiLin, 130118 People's Republic of China", 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5100394166', 'display_name': 'Fang Li', 'orcid': 'https://orcid.org/0000-0001-9180-3615'}, 'institutions': [{'id': 'https://openalex.org/I4210152006', 'display_name': 'Jilin Agricultural University', 'ror': 'https://ror.org/05dmhhd41', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I4210152006']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Li Fang', 'raw_affiliation_strings': ["College of Food Science and Engineering, Jilin Agricultural University, Changchun, 130118 People's Republic of China", "National Engineering Laboratory on Wheat and Corn Further Processing, Changchun, JiLin, 130118 People's Republic of China"], 'affiliations': [{'raw_affiliation_string': "College of Food Science and Engineering, Jilin Agricultural University, Changchun, 130118 People's Republic of China", 'institution_ids': ['https://openalex.org/I4210152006']}, {'raw_affiliation_string': "National Engineering Laboratory on Wheat and Corn Further Processing, Changchun, JiLin, 130118 People's Republic of China", 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5115590051', 'display_name': 'Chunlei Liu', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210152006', 'display_name': 'Jilin Agricultural University', 'ror': 'https://ror.org/05dmhhd41', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I4210152006']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Chunlei Liu', 'raw_affiliation_strings': ["College of Food Science and Engineering, Jilin Agricultural University, Changchun, 130118 People's Republic of China", "National Engineering Laboratory on Wheat and Corn Further Processing, Changchun, JiLin, 130118 People's Republic of China"], 'affiliations': [{'raw_affiliation_string': "National Engineering Laboratory on Wheat and Corn Further Processing, Changchun, JiLin, 130118 People's Republic of China", 'institution_ids': []}, {'raw_affiliation_string': "College of Food Science and Engineering, Jilin Agricultural University, Changchun, 130118 People's Republic of China", 'institution_ids': ['https://openalex.org/I4210152006']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5112040905', 'display_name': 'Weihong Min', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210152006', 'display_name': 'Jilin Agricultural University', 'ror': 'https://ror.org/05dmhhd41', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I4210152006']}], 'countries': ['CN'], 'is_corresponding': True, 'raw_author_name': 'Weihong Min', 'raw_affiliation_strings': ["College of Food Science and Engineering, Jilin Agricultural University, Changchun, 130118 People's Republic of China", "National Engineering Laboratory on Wheat and Corn Further Processing, Changchun, JiLin, 130118 People's Republic of China"], 'affiliations': [{'raw_affiliation_string': "College of Food Science and Engineering, Jilin Agricultural University, Changchun, 130118 People's Republic of China", 'institution_ids': ['https://openalex.org/I4210152006']}, {'raw_affiliation_string': "National Engineering Laboratory on Wheat and Corn Further Processing, Changchun, JiLin, 130118 People's Republic of China", 'institution_ids': []}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5101837876', 'display_name': 'Jingsheng Liu', 'orcid': 'https://orcid.org/0000-0002-6126-673X'}, 'institutions': [{'id': 'https://openalex.org/I4210152006', 'display_name': 'Jilin Agricultural University', 'ror': 'https://ror.org/05dmhhd41', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I4210152006']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Jingsheng Liu', 'raw_affiliation_strings': ["College of Food Science and Engineering, Jilin Agricultural University, Changchun, 130118 People's Republic of China", "National Engineering Laboratory on Wheat and Corn Further Processing, Changchun, JiLin, 130118 People's Republic of China"], 'affiliations': [{'raw_affiliation_string': "National Engineering Laboratory on Wheat and Corn Further Processing, Changchun, JiLin, 130118 People's Republic of China", 'institution_ids': []}, {'raw_affiliation_string': "College of Food Science and Engineering, Jilin Agricultural University, Changchun, 130118 People's Republic of China", 'institution_ids': ['https://openalex.org/I4210152006']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 1, 'corresponding_author_ids': ['https://openalex.org/A5112040905'], 'corresponding_institution_ids': ['https://openalex.org/I4210152006'], 'apc_list': {'value': 2500, 'currency': 'USD', 'value_usd': 2500, 'provenance': 'doaj'}, 'apc_paid': {'value': 2500, 'currency': 'USD', 'value_usd': 2500, 'provenance': 'doaj'}, 'fwci': 1.664, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 46, 'citation_normalized_percentile': {'value': 0.999983, 'is_in_top_1_percent': True, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 96, 'max': 97}, 'biblio': {'volume': '42', 'issue': '3', 'first_page': 'e12518', 'last_page': 'e12518'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T11561', 'display_name': 'Protein Hydrolysis and Bioactive Peptides', 'score': 0.9998, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T11561', 'display_name': 'Protein Hydrolysis and Bioactive Peptides', 'score': 0.9998, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T13551', 'display_name': 'Biochemical effects in animals', 'score': 0.9983, 'subfield': {'id': 'https://openalex.org/subfields/2737', 'display_name': 'Physiology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T11399', 'display_name': 'Muscle metabolism and nutrition', 'score': 0.9941, 'subfield': {'id': 'https://openalex.org/subfields/1307', 'display_name': 'Cell Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/glucokinase', 'display_name': 'Glucokinase', 'score': 0.613455}], 'concepts': [{'id': 'https://openalex.org/C98335778', 'wikidata': 'https://www.wikidata.org/wiki/Q425185', 'display_name': 'Glucokinase', 'level': 3, 'score': 0.613455}, {'id': 'https://openalex.org/C2779218259', 'wikidata': 'https://www.wikidata.org/wiki/Q2453469', 'display_name': 'Juglans', 'level': 2, 'score': 0.494221}, {'id': 'https://openalex.org/C2779306644', 'wikidata': 'https://www.wikidata.org/wiki/Q2002370', 'display_name': 'Insulin', 'level': 2, 'score': 0.48692977}, {'id': 'https://openalex.org/C555293320', 'wikidata': 'https://www.wikidata.org/wiki/Q12206', 'display_name': 'Diabetes mellitus', 'level': 2, 'score': 0.42191744}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.41083524}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.39267272}, {'id': 'https://openalex.org/C31903555', 'wikidata': 'https://www.wikidata.org/wiki/Q1637030', 'display_name': 'Food science', 'level': 1, 'score': 0.3753625}, {'id': 'https://openalex.org/C556039675', 'wikidata': 'https://www.wikidata.org/wiki/Q771035', 'display_name': 'Traditional medicine', 'level': 1, 'score': 0.3200629}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.29980522}, {'id': 'https://openalex.org/C181199279', 'wikidata': 'https://www.wikidata.org/wiki/Q8047', 'display_name': 'Enzyme', 'level': 2, 'score': 0.28021574}, {'id': 'https://openalex.org/C134018914', 'wikidata': 'https://www.wikidata.org/wiki/Q162606', 'display_name': 'Endocrinology', 'level': 1, 'score': 0.27850989}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.24151719}], 'mesh': [], 'locations_count': 1, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.1111/jfbc.12518', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S53703007', 'display_name': 'Journal of Food Biochemistry', 'issn_l': '0145-8884', 'issn': ['0145-8884', '1745-4514'], 'is_oa': True, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320595', 'host_organization_name': 'Wiley', 'host_organization_lineage': ['https://openalex.org/P4310320595'], 'host_organization_lineage_names': ['Wiley'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1111/jfbc.12518', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S53703007', 'display_name': 'Journal of Food Biochemistry', 'issn_l': '0145-8884', 'issn': ['0145-8884', '1745-4514'], 'is_oa': True, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320595', 'host_organization_name': 'Wiley', 'host_organization_lineage': ['https://openalex.org/P4310320595'], 'host_organization_lineage_names': ['Wiley'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 39, 'referenced_works': ['https://openalex.org/W1570228473', 'https://openalex.org/W1604596593', 'https://openalex.org/W1988950261', 'https://openalex.org/W2000999406', 'https://openalex.org/W2013188890', 'https://openalex.org/W2015486015', 'https://openalex.org/W2032980460', 'https://openalex.org/W2039762060', 'https://openalex.org/W2055350818', 'https://openalex.org/W2066675191', 'https://openalex.org/W2079470195', 'https://openalex.org/W2089462632', 'https://openalex.org/W2091543361', 'https://openalex.org/W2094641040', 'https://openalex.org/W2114041992', 'https://openalex.org/W2116765782', 'https://openalex.org/W2130230005', 'https://openalex.org/W2159251461', 'https://openalex.org/W2165884492', 'https://openalex.org/W2174637709', 'https://openalex.org/W2291653093', 'https://openalex.org/W2296585153', 'https://openalex.org/W2463656216', 'https://openalex.org/W2467821377', 'https://openalex.org/W2507403919', 'https://openalex.org/W2513691179', 'https://openalex.org/W2522690786', 'https://openalex.org/W2539135165', 'https://openalex.org/W2543761832', 'https://openalex.org/W2554039968', 'https://openalex.org/W2564151079', 'https://openalex.org/W2572559258', 'https://openalex.org/W2579293418', 'https://openalex.org/W2583155014', 'https://openalex.org/W2588122889', 'https://openalex.org/W2605732424', 'https://openalex.org/W2713210942', 'https://openalex.org/W2951244841', 'https://openalex.org/W2951484080'], 'related_works': ['https://openalex.org/W90262143', 'https://openalex.org/W4299366526', 'https://openalex.org/W3183219936', 'https://openalex.org/W2789167028', 'https://openalex.org/W2380167832', 'https://openalex.org/W2376037314', 'https://openalex.org/W2049016439', 'https://openalex.org/W2010373010', 'https://openalex.org/W1988394752', 'https://openalex.org/W1963836299'], 'abstract_inverted_index': {'Bioactive': [0], 'peptides': [1, 27, 270], 'derived': [2], 'from': [3, 30], 'plant': [4, 163], 'proteins': [5, 33], 'are': [6], 'promising': [7], 'sources': [8], 'for': [9, 291], 'the': [10, 21, 31, 51, 127, 137, 142, 154, 161, 177, 217, 226, 255, 282, 292], 'development': [11], 'safe': [12], 'hypoglycemics.': [13], 'The': [14, 223], 'present': [15, 227], 'study': [16, 228], 'was': [17], 'designed': [18], 'to': [19, 135, 189, 212], 'investigate': [20], 'antidiabetic': [22, 128, 234, 269], 'activity': [23, 235], 'of': [24, 34, 106, 130, 139, 144, 160, 179, 197, 225, 267, 284, 294], 'walnut': [25, 221], 'hydrolyzed': [26], '(WHPs)': [28], 'obtained': [29], 'fruit': [32, 166], 'Juglans': [35, 148], 'mandshurica': [36, 149], 'Maxim.': [37], 'In': [38, 67], 'vitro': [39], 'results': [40, 125, 224], 'showed': [41, 110, 232], 'that': [42, 111, 230, 271], 'WHPs': [43, 74, 112, 131, 140, 231], 'with': [44, 69, 75], 'medium': [45, 76], 'molecular': [46, 77], 'weights': [47, 78], '(3–10': [48], 'kDa)': [49], 'exhibited': [50], 'highest': [52], 'α-glucosidase': [53, 238], 'inhibitory': [54], 'rate': [55], '(61.73%)': [56], 'and': [57, 86, 92, 95, 100, 119, 132, 173, 181, 185, 201, 244, 247], 'significantly': [58, 113], 'increased': [59, 87], 'extracellular': [60], 'glucose': [61, 82, 240, 258], 'consumption': [62], 'in': [63, 141, 170, 176, 216, 281], 'insulin-resistant': [64], 'HepG2': [65], 'cells.': [66], 'mice': [68], 'streptozotocin-induced': [70], 'type': [71, 295], '2': [72, 296], 'diabetes,': [73], 'reduced': [79], 'fasting': [80, 256], 'blood': [81, 257], 'levels': [83, 97, 249], 'by': [84, 90, 98, 236, 253], '64.82%': [85], 'insulin': [88, 242], 'secretion': [89], '23.71%': [91], 'liver': [93, 245], 'glucokinase': [94, 246], 'glycogen': [96, 248], '69.54': [99], '76.19%,': [101], 'respectively.': [102], 'Furthermore,': [103], 'an': [104, 208], 'analysis': [105], 'serum': [107, 115], 'lipid': [108], 'profiles': [109], 'decreased': [114], 'total': [116], 'cholesterol,': [117], 'triglyceride,': [118], 'low-density': [120], 'lipoprotein': [121], 'cholesterol': [122], 'levels.': [123], 'Our': [124], 'indicate': [126], 'potential': [129], 'provide': [133], 'evidence': [134], 'support': [136], 'application': [138], 'treatment': [143, 293], 'diabetes.': [145, 297], 'Practical': [146], 'applications': [147], 'Maxim.,': [150], 'commonly': [151], 'known': [152], 'as': [153, 250, 252, 276, 288], 'Manchurian': [155, 220], 'walnut,': [156], 'is': [157, 167, 174], 'a': [158, 213, 264, 277, 289], 'member': [159], 'Juglandaceae': [162], 'family.': [164], 'Its': [165], 'extensively': [168], 'consumed': [169], 'northeast': [171], 'China': [172], 'used': [175, 275], 'production': [178], 'dairy': [180], 'bakery': [182], 'products,': [183], 'candy,': [184], 'cooking': [186], 'oil': [187], 'owing': [188], 'its': [190], 'high': [191], 'protein': [192], 'content': [193], '(about': [194], '30%),': [195], 'abundance': [196], 'essential': [198], 'amino': [199], 'acids,': [200], 'easy': [202], 'digestibility.': [203], 'Hence,': [204], 'there': [205], 'has': [206], 'been': [207], 'immense': [209], 'increase,': [210], 'up': [211], 'million': [214], 'hectare,': [215], 'area': [218], 'under': [219], 'cultivation.': [222], 'indicated': [229], 'significant': [233], 'improving': [237], 'activity,': [239], 'metabolism,': [241], 'secretion,': [243], 'well': [251], 'decreasing': [254], 'level.': [259], 'These': [260], 'findings': [261], 'have': [262], 'identified': [263], 'green': [265], 'source': [266], 'novel': [268], 'can': [272], 'either': [273], 'be': [274], 'functional': [278], 'food': [279], 'ingredient': [280], 'management': [283], 'hyperglycemia': [285], 'or': [286], 'developed': [287], 'drug': [290]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2789887784', 'counts_by_year': [{'year': 2024, 'cited_by_count': 10}, {'year': 2023, 'cited_by_count': 12}, {'year': 2022, 'cited_by_count': 5}, {'year': 2021, 'cited_by_count': 6}, {'year': 2020, 'cited_by_count': 7}, {'year': 2019, 'cited_by_count': 4}, {'year': 2018, 'cited_by_count': 2}], 'updated_date': '2024-12-24T09:09:10.132911', 'created_date': '2018-03-29'}