Mutational profiling of isolated myeloid sarcomas and utility of serum 2HG as biomarker of IDH1/2 mutations

Name: Work Video:
Duration: 3 min 30 s
Christophe Willekens; Aline Renneville; Sophie Broutin; Véronique Saada; Jean‐Baptiste Micol; J Delahousse; Vianney Poinsignon; Claire Bories; Céline Berthon; Raphaël Itzykson; Nicolas Boissel; Cyril Quivoron; Marie Terroir-Cassou-Mounat; Jacques Bosq; Claude Preudhomme; Angélo Paci; Virginie Penard‐Lacronique; Stéphane de Botton
{'id': 'https://openalex.org/W2789513661', 'doi': 'https://doi.org/10.1038/s41375-018-0056-6', 'title': 'Mutational profiling of isolated myeloid sarcomas and utility of serum 2HG as biomarker of IDH1/2 mutations', 'display_name': 'Mutational profiling of isolated myeloid sarcomas and utility of serum 2HG as biomarker of IDH1/2 mutations', 'publication_year': 2018, 'publication_date': '2018-02-25', 'ids': {'openalex': 'https://openalex.org/W2789513661', 'doi': 'https://doi.org/10.1038/s41375-018-0056-6', 'mag': '2789513661', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/29479068'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1038/s41375-018-0056-6', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S149476849', 'display_name': 'Leukemia', 'issn_l': '0887-6924', 'issn': ['0887-6924', '1476-5551'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310319965', 'host_organization_name': 'Springer Nature', 'host_organization_lineage': ['https://openalex.org/P4310319965'], 'host_organization_lineage_names': ['Springer Nature'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5028073020', 'display_name': 'Christophe Willekens', 'orcid': 'https://orcid.org/0000-0001-9814-8537'}, 'institutions': [{'id': 'https://openalex.org/I277688954', 'display_name': 'Université Paris-Saclay', 'ror': 'https://ror.org/03xjwb503', 'country_code': 'FR', 'type': 'education', 'lineage': ['https://openalex.org/I277688954']}, {'id': 'https://openalex.org/I2801843802', 'display_name': 'Institut Gustave Roussy', 'ror': 'https://ror.org/0321g0743', 'country_code': 'FR', 'type': 'facility', 'lineage': ['https://openalex.org/I2801843802']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'Christophe Willekens', 'raw_affiliation_strings': ["Département d'Hématologie, Gustave Roussy, Université Paris-Saclay, F-94805, Villejuif, France"], 'affiliations': [{'raw_affiliation_string': "Département d'Hématologie, Gustave Roussy, Université Paris-Saclay, F-94805, Villejuif, France", 'institution_ids': ['https://openalex.org/I277688954', 'https://openalex.org/I2801843802']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5059057760', 'display_name': 'Aline Renneville', 'orcid': 'https://orcid.org/0000-0003-0805-9640'}, 'institutions': [{'id': 'https://openalex.org/I3018718406', 'display_name': 'Centre Hospitalier Universitaire de Lille', 'ror': 'https://ror.org/02ppyfa04', 'country_code': 'FR', 'type': 'healthcare', 'lineage': ['https://openalex.org/I3018718406']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'Aline Renneville', 'raw_affiliation_strings': ["Centre de Biologie-Pathologie, Laboratoire d'hématologie, Centre Hospitalier Universitaire de Lille, Lille, France"], 'affiliations': [{'raw_affiliation_string': "Centre de Biologie-Pathologie, Laboratoire d'hématologie, Centre Hospitalier Universitaire de Lille, Lille, France", 'institution_ids': ['https://openalex.org/I3018718406']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5069910012', 'display_name': 'Sophie Broutin', 'orcid': 'https://orcid.org/0000-0001-6333-3636'}, 'institutions': [{'id': 'https://openalex.org/I277688954', 'display_name': 'Université Paris-Saclay', 'ror': 'https://ror.org/03xjwb503', 'country_code': 'FR', 'type': 'education', 'lineage': ['https://openalex.org/I277688954']}, {'id': 'https://openalex.org/I2801843802', 'display_name': 'Institut Gustave Roussy', 'ror': 'https://ror.org/0321g0743', 'country_code': 'FR', 'type': 'facility', 'lineage': ['https://openalex.org/I2801843802']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'Sophie Broutin', 'raw_affiliation_strings': ['Département de Biologie-Pathologie, Gustave Roussy, Université Paris-Saclay, F-94805, Villejuif, France'], 'affiliations': [{'raw_affiliation_string': 'Département de Biologie-Pathologie, Gustave Roussy, Université Paris-Saclay, F-94805, Villejuif, France', 'institution_ids': ['https://openalex.org/I277688954', 'https://openalex.org/I2801843802']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5039143164', 'display_name': 'Véronique Saada', 'orcid': 'https://orcid.org/0000-0001-8021-9050'}, 'institutions': [{'id': 'https://openalex.org/I2801843802', 'display_name': 'Institut Gustave Roussy', 'ror': 'https://ror.org/0321g0743', 'country_code': 'FR', 'type': 'facility', 'lineage': ['https://openalex.org/I2801843802']}, {'id': 'https://openalex.org/I277688954', 'display_name': 'Université Paris-Saclay', 'ror': 'https://ror.org/03xjwb503', 'country_code': 'FR', 'type': 'education', 'lineage': ['https://openalex.org/I277688954']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'Véronique Saada', 'raw_affiliation_strings': ['Département de Biologie-Pathologie, Gustave Roussy, Université Paris-Saclay, F-94805, Villejuif, France'], 'affiliations': [{'raw_affiliation_string': 'Département de Biologie-Pathologie, Gustave Roussy, Université Paris-Saclay, F-94805, Villejuif, France', 'institution_ids': ['https://openalex.org/I2801843802', 'https://openalex.org/I277688954']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5008450550', 'display_name': 'Jean‐Baptiste Micol', 'orcid': 'https://orcid.org/0000-0003-0934-294X'}, 'institutions': [{'id': 'https://openalex.org/I277688954', 'display_name': 'Université Paris-Saclay', 'ror': 'https://ror.org/03xjwb503', 'country_code': 'FR', 'type': 'education', 'lineage': ['https://openalex.org/I277688954']}, {'id': 'https://openalex.org/I2801843802', 'display_name': 'Institut Gustave Roussy', 'ror': 'https://ror.org/0321g0743', 'country_code': 'FR', 'type': 'facility', 'lineage': ['https://openalex.org/I2801843802']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'Jean-Baptiste Micol', 'raw_affiliation_strings': ["Département d'Hématologie, Gustave Roussy, Université Paris-Saclay, F-94805, Villejuif, France"], 'affiliations': [{'raw_affiliation_string': "Département d'Hématologie, Gustave Roussy, Université Paris-Saclay, F-94805, Villejuif, France", 'institution_ids': ['https://openalex.org/I277688954', 'https://openalex.org/I2801843802']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5032039485', 'display_name': 'J Delahousse', 'orcid': 'https://orcid.org/0000-0002-2346-9608'}, 'institutions': [{'id': 'https://openalex.org/I2801843802', 'display_name': 'Institut Gustave Roussy', 'ror': 'https://ror.org/0321g0743', 'country_code': 'FR', 'type': 'facility', 'lineage': ['https://openalex.org/I2801843802']}, {'id': 'https://openalex.org/I277688954', 'display_name': 'Université Paris-Saclay', 'ror': 'https://ror.org/03xjwb503', 'country_code': 'FR', 'type': 'education', 'lineage': ['https://openalex.org/I277688954']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'Julia Delahousse', 'raw_affiliation_strings': ['Département de Biologie-Pathologie, Gustave Roussy, Université Paris-Saclay, F-94805, Villejuif, France'], 'affiliations': [{'raw_affiliation_string': 'Département de Biologie-Pathologie, Gustave Roussy, Université Paris-Saclay, F-94805, Villejuif, France', 'institution_ids': ['https://openalex.org/I2801843802', 'https://openalex.org/I277688954']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5070329039', 'display_name': 'Vianney Poinsignon', 'orcid': 'https://orcid.org/0000-0002-4945-5431'}, 'institutions': [{'id': 'https://openalex.org/I277688954', 'display_name': 'Université Paris-Saclay', 'ror': 'https://ror.org/03xjwb503', 'country_code': 'FR', 'type': 'education', 'lineage': ['https://openalex.org/I277688954']}, {'id': 'https://openalex.org/I2801843802', 'display_name': 'Institut Gustave Roussy', 'ror': 'https://ror.org/0321g0743', 'country_code': 'FR', 'type': 'facility', 'lineage': ['https://openalex.org/I2801843802']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'Vianney Poinsignon', 'raw_affiliation_strings': ['Département de Biologie-Pathologie, Gustave Roussy, Université Paris-Saclay, F-94805, Villejuif, France'], 'affiliations': [{'raw_affiliation_string': 'Département de Biologie-Pathologie, Gustave Roussy, Université Paris-Saclay, F-94805, Villejuif, France', 'institution_ids': ['https://openalex.org/I277688954', 'https://openalex.org/I2801843802']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5112487008', 'display_name': 'Claire Bories', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210155195', 'display_name': 'Hôpital Claude Huriez', 'ror': 'https://ror.org/05cpv3t46', 'country_code': 'FR', 'type': 'healthcare', 'lineage': ['https://openalex.org/I3018718406', 'https://openalex.org/I4210155195']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'Claire Bories', 'raw_affiliation_strings': ['Hôpital Claude Huriez, Centre Hospitalier Universitaire Lille, Service des maladies du sang, Lille, France'], 'affiliations': [{'raw_affiliation_string': 'Hôpital Claude Huriez, Centre Hospitalier Universitaire Lille, Service des maladies du sang, Lille, France', 'institution_ids': ['https://openalex.org/I4210155195']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5081514634', 'display_name': 'Céline Berthon', 'orcid': 'https://orcid.org/0000-0002-3474-2577'}, 'institutions': [{'id': 'https://openalex.org/I4210155195', 'display_name': 'Hôpital Claude Huriez', 'ror': 'https://ror.org/05cpv3t46', 'country_code': 'FR', 'type': 'healthcare', 'lineage': ['https://openalex.org/I3018718406', 'https://openalex.org/I4210155195']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'Céline Berthon', 'raw_affiliation_strings': ['Hôpital Claude Huriez, Centre Hospitalier Universitaire Lille, Service des maladies du sang, Lille, France'], 'affiliations': [{'raw_affiliation_string': 'Hôpital Claude Huriez, Centre Hospitalier Universitaire Lille, Service des maladies du sang, Lille, France', 'institution_ids': ['https://openalex.org/I4210155195']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5004876764', 'display_name': 'Raphaël Itzykson', 'orcid': 'https://orcid.org/0000-0003-2139-6262'}, 'institutions': [{'id': 'https://openalex.org/I4210144610', 'display_name': 'Hôpital Saint-Louis', 'ror': 'https://ror.org/049am9t04', 'country_code': 'FR', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210097159', 'https://openalex.org/I4210144610']}, {'id': 'https://openalex.org/I169173203', 'display_name': 'Délégation Paris 7', 'ror': 'https://ror.org/00bw5n526', 'country_code': 'FR', 'type': 'government', 'lineage': ['https://openalex.org/I154526488', 'https://openalex.org/I169173203']}, {'id': 'https://openalex.org/I4210097159', 'display_name': 'Assistance Publique – Hôpitaux de Paris', 'ror': 'https://ror.org/00pg5jh14', 'country_code': 'FR', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210097159']}, {'id': 'https://openalex.org/I204730241', 'display_name': 'Université Paris Cité', 'ror': 'https://ror.org/05f82e368', 'country_code': 'FR', 'type': 'education', 'lineage': ['https://openalex.org/I204730241']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'Raphael Itzykson', 'raw_affiliation_strings': ["Département d'Hématologie, Hôpital Saint-Louis, Assistance Publique-Hôpitaux de Paris, Université Paris Diderot, 75475, Paris, France"], 'affiliations': [{'raw_affiliation_string': "Département d'Hématologie, Hôpital Saint-Louis, Assistance Publique-Hôpitaux de Paris, Université Paris Diderot, 75475, Paris, France", 'institution_ids': ['https://openalex.org/I4210144610', 'https://openalex.org/I169173203', 'https://openalex.org/I4210097159', 'https://openalex.org/I204730241']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5076973611', 'display_name': 'Nicolas Boissel', 'orcid': 'https://orcid.org/0000-0003-2091-7927'}, 'institutions': [{'id': 'https://openalex.org/I4210144610', 'display_name': 'Hôpital Saint-Louis', 'ror': 'https://ror.org/049am9t04', 'country_code': 'FR', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210097159', 'https://openalex.org/I4210144610']}, {'id': 'https://openalex.org/I169173203', 'display_name': 'Délégation Paris 7', 'ror': 'https://ror.org/00bw5n526', 'country_code': 'FR', 'type': 'government', 'lineage': ['https://openalex.org/I154526488', 'https://openalex.org/I169173203']}, {'id': 'https://openalex.org/I4210097159', 'display_name': 'Assistance Publique – Hôpitaux de Paris', 'ror': 'https://ror.org/00pg5jh14', 'country_code': 'FR', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210097159']}, {'id': 'https://openalex.org/I204730241', 'display_name': 'Université Paris Cité', 'ror': 'https://ror.org/05f82e368', 'country_code': 'FR', 'type': 'education', 'lineage': ['https://openalex.org/I204730241']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'Nicolas Boissel', 'raw_affiliation_strings': ["Département d'Hématologie, Hôpital Saint-Louis, Assistance Publique-Hôpitaux de Paris, Université Paris Diderot, 75475, Paris, France"], 'affiliations': [{'raw_affiliation_string': "Département d'Hématologie, Hôpital Saint-Louis, Assistance Publique-Hôpitaux de Paris, Université Paris Diderot, 75475, Paris, France", 'institution_ids': ['https://openalex.org/I4210144610', 'https://openalex.org/I169173203', 'https://openalex.org/I4210097159', 'https://openalex.org/I204730241']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5054440976', 'display_name': 'Cyril Quivoron', 'orcid': 'https://orcid.org/0000-0002-9871-0187'}, 'institutions': [{'id': 'https://openalex.org/I154526488', 'display_name': 'Inserm', 'ror': 'https://ror.org/02vjkv261', 'country_code': 'FR', 'type': 'government', 'lineage': ['https://openalex.org/I154526488']}, {'id': 'https://openalex.org/I277688954', 'display_name': 'Université Paris-Saclay', 'ror': 'https://ror.org/03xjwb503', 'country_code': 'FR', 'type': 'education', 'lineage': ['https://openalex.org/I277688954']}, {'id': 'https://openalex.org/I2801843802', 'display_name': 'Institut Gustave Roussy', 'ror': 'https://ror.org/0321g0743', 'country_code': 'FR', 'type': 'facility', 'lineage': ['https://openalex.org/I2801843802']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'Cyril Quivoron', 'raw_affiliation_strings': ['Inserm U1170, Gustave Roussy, Université Paris-Saclay, 94805, Villejuif, France'], 'affiliations': [{'raw_affiliation_string': 'Inserm U1170, Gustave Roussy, Université Paris-Saclay, 94805, Villejuif, France', 'institution_ids': ['https://openalex.org/I154526488', 'https://openalex.org/I277688954', 'https://openalex.org/I2801843802']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5027733848', 'display_name': 'Marie Terroir-Cassou-Mounat', 'orcid': 'https://orcid.org/0000-0003-1395-8472'}, 'institutions': [{'id': 'https://openalex.org/I2801843802', 'display_name': 'Institut Gustave Roussy', 'ror': 'https://ror.org/0321g0743', 'country_code': 'FR', 'type': 'facility', 'lineage': ['https://openalex.org/I2801843802']}, {'id': 'https://openalex.org/I277688954', 'display_name': 'Université Paris-Saclay', 'ror': 'https://ror.org/03xjwb503', 'country_code': 'FR', 'type': 'education', 'lineage': ['https://openalex.org/I277688954']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'Marie Terroir-Cassou-Mounat', 'raw_affiliation_strings': ['Département de médecine nucléaire, Gustave Roussy, Université Paris-Saclay, F-94805, Villejuif, France'], 'affiliations': [{'raw_affiliation_string': 'Département de médecine nucléaire, Gustave Roussy, Université Paris-Saclay, F-94805, Villejuif, France', 'institution_ids': ['https://openalex.org/I2801843802', 'https://openalex.org/I277688954']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5105781562', 'display_name': 'Jacques Bosq', 'orcid': 'https://orcid.org/0000-0003-0429-3712'}, 'institutions': [{'id': 'https://openalex.org/I2801843802', 'display_name': 'Institut Gustave Roussy', 'ror': 'https://ror.org/0321g0743', 'country_code': 'FR', 'type': 'facility', 'lineage': ['https://openalex.org/I2801843802']}, {'id': 'https://openalex.org/I277688954', 'display_name': 'Université Paris-Saclay', 'ror': 'https://ror.org/03xjwb503', 'country_code': 'FR', 'type': 'education', 'lineage': ['https://openalex.org/I277688954']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'Jacques Bosq', 'raw_affiliation_strings': ['Département de Biologie-Pathologie, Gustave Roussy, Université Paris-Saclay, F-94805, Villejuif, France'], 'affiliations': [{'raw_affiliation_string': 'Département de Biologie-Pathologie, Gustave Roussy, Université Paris-Saclay, F-94805, Villejuif, France', 'institution_ids': ['https://openalex.org/I2801843802', 'https://openalex.org/I277688954']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5018416096', 'display_name': 'Claude Preudhomme', 'orcid': 'https://orcid.org/0000-0002-1267-9546'}, 'institutions': [{'id': 'https://openalex.org/I3018718406', 'display_name': 'Centre Hospitalier Universitaire de Lille', 'ror': 'https://ror.org/02ppyfa04', 'country_code': 'FR', 'type': 'healthcare', 'lineage': ['https://openalex.org/I3018718406']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'Claude Preudhomme', 'raw_affiliation_strings': ["Centre de Biologie-Pathologie, Laboratoire d'hématologie, Centre Hospitalier Universitaire de Lille, Lille, France"], 'affiliations': [{'raw_affiliation_string': "Centre de Biologie-Pathologie, Laboratoire d'hématologie, Centre Hospitalier Universitaire de Lille, Lille, France", 'institution_ids': ['https://openalex.org/I3018718406']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5013335730', 'display_name': 'Angélo Paci', 'orcid': 'https://orcid.org/0000-0002-4849-0825'}, 'institutions': [{'id': 'https://openalex.org/I2801843802', 'display_name': 'Institut Gustave Roussy', 'ror': 'https://ror.org/0321g0743', 'country_code': 'FR', 'type': 'facility', 'lineage': ['https://openalex.org/I2801843802']}, {'id': 'https://openalex.org/I277688954', 'display_name': 'Université Paris-Saclay', 'ror': 'https://ror.org/03xjwb503', 'country_code': 'FR', 'type': 'education', 'lineage': ['https://openalex.org/I277688954']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'Angelo Paci', 'raw_affiliation_strings': ['Département de Biologie-Pathologie, Gustave Roussy, Université Paris-Saclay, F-94805, Villejuif, France'], 'affiliations': [{'raw_affiliation_string': 'Département de Biologie-Pathologie, Gustave Roussy, Université Paris-Saclay, F-94805, Villejuif, France', 'institution_ids': ['https://openalex.org/I2801843802', 'https://openalex.org/I277688954']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5085860314', 'display_name': 'Virginie Penard‐Lacronique', 'orcid': 'https://orcid.org/0000-0001-9435-7331'}, 'institutions': [{'id': 'https://openalex.org/I277688954', 'display_name': 'Université Paris-Saclay', 'ror': 'https://ror.org/03xjwb503', 'country_code': 'FR', 'type': 'education', 'lineage': ['https://openalex.org/I277688954']}, {'id': 'https://openalex.org/I2801843802', 'display_name': 'Institut Gustave Roussy', 'ror': 'https://ror.org/0321g0743', 'country_code': 'FR', 'type': 'facility', 'lineage': ['https://openalex.org/I2801843802']}, {'id': 'https://openalex.org/I154526488', 'display_name': 'Inserm', 'ror': 'https://ror.org/02vjkv261', 'country_code': 'FR', 'type': 'government', 'lineage': ['https://openalex.org/I154526488']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'Virginie Penard-Lacronique', 'raw_affiliation_strings': ['Inserm U1170, Gustave Roussy, Université Paris-Saclay, 94805, Villejuif, France'], 'affiliations': [{'raw_affiliation_string': 'Inserm U1170, Gustave Roussy, Université Paris-Saclay, 94805, Villejuif, France', 'institution_ids': ['https://openalex.org/I277688954', 'https://openalex.org/I2801843802', 'https://openalex.org/I154526488']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5017435311', 'display_name': 'Stéphane de Botton', 'orcid': 'https://orcid.org/0000-0002-8126-4942'}, 'institutions': [{'id': 'https://openalex.org/I277688954', 'display_name': 'Université Paris-Saclay', 'ror': 'https://ror.org/03xjwb503', 'country_code': 'FR', 'type': 'education', 'lineage': ['https://openalex.org/I277688954']}, {'id': 'https://openalex.org/I154526488', 'display_name': 'Inserm', 'ror': 'https://ror.org/02vjkv261', 'country_code': 'FR', 'type': 'government', 'lineage': ['https://openalex.org/I154526488']}, {'id': 'https://openalex.org/I2801843802', 'display_name': 'Institut Gustave Roussy', 'ror': 'https://ror.org/0321g0743', 'country_code': 'FR', 'type': 'facility', 'lineage': ['https://openalex.org/I2801843802']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'Stéphane De Botton', 'raw_affiliation_strings': ['Inserm U1170, Gustave Roussy, Université Paris-Saclay, 94805, Villejuif, France'], 'affiliations': [{'raw_affiliation_string': 'Inserm U1170, Gustave Roussy, Université Paris-Saclay, 94805, Villejuif, France', 'institution_ids': ['https://openalex.org/I277688954', 'https://openalex.org/I154526488', 'https://openalex.org/I2801843802']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 9, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': {'value': 3890, 'currency': 'EUR', 'value_usd': 4790, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 1.669, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 19, 'citation_normalized_percentile': {'value': 0.883983, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 90, 'max': 91}, 'biblio': {'volume': '32', 'issue': '9', 'first_page': '2008', 'last_page': '2081'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10309', 'display_name': 'Acute Myeloid Leukemia Research', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/2720', 'display_name': 'Hematology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10309', 'display_name': 'Acute Myeloid Leukemia Research', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/2720', 'display_name': 'Hematology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10253', 'display_name': 'Sarcoma Diagnosis and Treatment', 'score': 0.9978, 'subfield': {'id': 'https://openalex.org/subfields/2740', 'display_name': 'Pulmonary and Respiratory Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T13374', 'display_name': 'Hematological disorders and diagnostics', 'score': 0.9968, 'subfield': {'id': 'https://openalex.org/subfields/2711', 'display_name': 'Emergency Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [], 'concepts': [{'id': 'https://openalex.org/C127848430', 'wikidata': 'https://www.wikidata.org/wiki/Q18027543', 'display_name': 'IDH1', 'level': 4, 'score': 0.81532586}, {'id': 'https://openalex.org/C2779282312', 'wikidata': 'https://www.wikidata.org/wiki/Q1956561', 'display_name': 'Myeloid', 'level': 2, 'score': 0.6021614}, {'id': 'https://openalex.org/C2781197716', 'wikidata': 'https://www.wikidata.org/wiki/Q864574', 'display_name': 'Biomarker', 'level': 2, 'score': 0.58188397}, {'id': 'https://openalex.org/C2778729363', 'wikidata': 'https://www.wikidata.org/wiki/Q11688946', 'display_name': 'Myeloid leukemia', 'level': 2, 'score': 0.52373314}, {'id': 'https://openalex.org/C502942594', 'wikidata': 'https://www.wikidata.org/wiki/Q3421914', 'display_name': 'Cancer research', 'level': 1, 'score': 0.4737302}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.36899793}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.36669296}, {'id': 'https://openalex.org/C501734568', 'wikidata': 'https://www.wikidata.org/wiki/Q42918', 'display_name': 'Mutation', 'level': 3, 'score': 0.3508737}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.28886485}, {'id': 'https://openalex.org/C54355233', 'wikidata': 'https://www.wikidata.org/wiki/Q7162', 'display_name': 'Genetics', 'level': 1, 'score': 0.27540922}], 'mesh': [{'descriptor_ui': 'D005977', 'descriptor_name': 'Glutarates', 'qualifier_ui': 'Q000097', 'qualifier_name': 'blood', 'is_major_topic': True}, {'descriptor_ui': 'D007521', 'descriptor_name': 'Isocitrate Dehydrogenase', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': True}, {'descriptor_ui': 'D009154', 'descriptor_name': 'Mutation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D023981', 'descriptor_name': 'Sarcoma, Myeloid', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': True}, {'descriptor_ui': 'D023981', 'descriptor_name': 'Sarcoma, Myeloid', 'qualifier_ui': 'Q000097', 'qualifier_name': 'blood', 'is_major_topic': True}, {'descriptor_ui': 'D000293', 'descriptor_name': 'Adolescent', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000328', 'descriptor_name': 'Adult', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000368', 'descriptor_name': 'Aged', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015415', 'descriptor_name': 'Biomarkers', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001706', 'descriptor_name': 'Biopsy', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004252', 'descriptor_name': 'DNA Mutational Analysis', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005260', 'descriptor_name': 'Female', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005977', 'descriptor_name': 'Glutarates', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007521', 'descriptor_name': 'Isocitrate Dehydrogenase', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008297', 'descriptor_name': 'Male', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008875', 'descriptor_name': 'Middle Aged', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D049268', 'descriptor_name': 'Positron-Emission Tomography', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D023981', 'descriptor_name': 'Sarcoma, Myeloid', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D023981', 'descriptor_name': 'Sarcoma, Myeloid', 'qualifier_ui': 'Q000175', 'qualifier_name': 'diagnosis', 'is_major_topic': False}, {'descriptor_ui': 'D055815', 'descriptor_name': 'Young Adult', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 3, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1038/s41375-018-0056-6', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S149476849', 'display_name': 'Leukemia', 'issn_l': '0887-6924', 'issn': ['0887-6924', '1476-5551'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310319965', 'host_organization_name': 'Springer Nature', 'host_organization_lineage': ['https://openalex.org/P4310319965'], 'host_organization_lineage_names': ['Springer Nature'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://hal.science/hal-04464390', 'pdf_url': None, 'source': None, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/29479068', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'display_name': 'Zero hunger', 'score': 0.59, 'id': 'https://metadata.un.org/sdg/2'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 16, 'referenced_works': ['https://openalex.org/W1968604811', 'https://openalex.org/W1983769365', 'https://openalex.org/W2009186097', 'https://openalex.org/W2021407059', 'https://openalex.org/W2023014046', 'https://openalex.org/W2042634892', 'https://openalex.org/W2047322423', 'https://openalex.org/W2066236650', 'https://openalex.org/W2118982859', 'https://openalex.org/W2219735937', 'https://openalex.org/W2342617640', 'https://openalex.org/W2465678433', 'https://openalex.org/W2510836133', 'https://openalex.org/W2555424581', 'https://openalex.org/W2566555267', 'https://openalex.org/W2623089849'], 'related_works': ['https://openalex.org/W4225329031', 'https://openalex.org/W3197827905', 'https://openalex.org/W3175212877', 'https://openalex.org/W2805394647', 'https://openalex.org/W2415936912', 'https://openalex.org/W2374499992', 'https://openalex.org/W2353247773', 'https://openalex.org/W2015207539', 'https://openalex.org/W2012639655', 'https://openalex.org/W1964249184'], 'abstract_inverted_index': None, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2789513661', 'counts_by_year': [{'year': 2024, 'cited_by_count': 1}, {'year': 2023, 'cited_by_count': 5}, {'year': 2022, 'cited_by_count': 4}, {'year': 2021, 'cited_by_count': 4}, {'year': 2020, 'cited_by_count': 4}, {'year': 2019, 'cited_by_count': 1}], 'updated_date': '2025-01-06T16:46:18.762915', 'created_date': '2018-03-29'}
Publication Information

Basic Information

Access and Citation

AI Researcher Chatbot

Primary Location

Authors

Topics

Keywords

Related Works
