Post-Transplantation Lymphoproliferative Disorders in Adults

Name: Work Video:
Duration: 3 min 30 s
Description: Solid-organ and hematopoietic stem-cell transplants are widely used for various life-threatening medical disorders. Prophylaxis against transplant rejection and graft-versus-host disease is often immunosuppressive and can increase the risk of lymphoproliferative disease.
Daan Dierickx; Thomas M. Habermann
{'id': 'https://openalex.org/W2786571997', 'doi': 'https://doi.org/10.1056/nejmra1702693', 'title': 'Post-Transplantation Lymphoproliferative Disorders in Adults', 'display_name': 'Post-Transplantation Lymphoproliferative Disorders in Adults', 'publication_year': 2018, 'publication_date': '2018-02-07', 'ids': {'openalex': 'https://openalex.org/W2786571997', 'doi': 'https://doi.org/10.1056/nejmra1702693', 'mag': '2786571997', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/29414277'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1056/nejmra1702693', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S62468778', 'display_name': 'New England Journal of Medicine', 'issn_l': '0028-4793', 'issn': ['0028-4793', '1533-4406'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320239', 'host_organization_name': 'Massachusetts Medical Society', 'host_organization_lineage': ['https://openalex.org/P4310320239'], 'host_organization_lineage_names': ['Massachusetts Medical Society'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'review', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5033063736', 'display_name': 'Daan Dierickx', 'orcid': 'https://orcid.org/0000-0002-8917-022X'}, 'institutions': [{'id': 'https://openalex.org/I99464096', 'display_name': 'KU Leuven', 'ror': 'https://ror.org/05f950310', 'country_code': 'BE', 'type': 'education', 'lineage': ['https://openalex.org/I99464096']}], 'countries': ['BE'], 'is_corresponding': False, 'raw_author_name': 'Daan Dierickx', 'raw_affiliation_strings': ['Laboratory for Experimental Hematology, Department of Oncology, University of Leuven, Leuven, Belgium'], 'affiliations': [{'raw_affiliation_string': 'Laboratory for Experimental Hematology, Department of Oncology, University of Leuven, Leuven, Belgium', 'institution_ids': ['https://openalex.org/I99464096']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5025688165', 'display_name': 'Thomas M. Habermann', 'orcid': 'https://orcid.org/0000-0003-3532-9132'}, 'institutions': [{'id': 'https://openalex.org/I4210125099', 'display_name': 'Mayo Clinic in Arizona', 'ror': 'https://ror.org/03jp40720', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1330342723', 'https://openalex.org/I4210125099']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Thomas M. Habermann', 'raw_affiliation_strings': ['Division of Hematology, Department of Medicine, Mayo Clinic, Rochester, MN'], 'affiliations': [{'raw_affiliation_string': 'Division of Hematology, Department of Medicine, Mayo Clinic, Rochester, MN', 'institution_ids': ['https://openalex.org/I4210125099']}]}], 'institution_assertions': [], 'countries_distinct_count': 2, 'institutions_distinct_count': 2, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 6.149, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 356, 'citation_normalized_percentile': {'value': 0.999406, 'is_in_top_1_percent': True, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 99, 'max': 100}, 'biblio': {'volume': '378', 'issue': '6', 'first_page': '549', 'last_page': '562'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10685', 'display_name': 'Viral-associated cancers and disorders', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/2730', 'display_name': 'Oncology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10685', 'display_name': 'Viral-associated cancers and disorders', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/2730', 'display_name': 'Oncology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T11827', 'display_name': 'Polyomavirus and related diseases', 'score': 0.9996, 'subfield': {'id': 'https://openalex.org/subfields/2730', 'display_name': 'Oncology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10981', 'display_name': 'Cytomegalovirus and herpesvirus research', 'score': 0.998, 'subfield': {'id': 'https://openalex.org/subfields/2713', 'display_name': 'Epidemiology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/lymphoproliferative-disorders', 'display_name': 'Lymphoproliferative Disorders', 'score': 0.86113673}, {'id': 'https://openalex.org/keywords/lymphoproliferative-disease', 'display_name': 'Lymphoproliferative disease', 'score': 0.7951899}, {'id': 'https://openalex.org/keywords/solid-organ', 'display_name': 'Solid organ', 'score': 0.51435983}, {'id': 'https://openalex.org/keywords/post-transplant-lymphoproliferative-disorder', 'display_name': 'Post-transplant lymphoproliferative disorder', 'score': 0.43923193}], 'concepts': [{'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.93793654}, {'id': 'https://openalex.org/C2776995267', 'wikidata': 'https://www.wikidata.org/wiki/Q4165484', 'display_name': 'Lymphoproliferative disorders', 'level': 3, 'score': 0.86113673}, {'id': 'https://openalex.org/C2910651325', 'wikidata': 'https://www.wikidata.org/wiki/Q4165484', 'display_name': 'Lymphoproliferative disease', 'level': 3, 'score': 0.7951899}, {'id': 'https://openalex.org/C2777408962', 'wikidata': 'https://www.wikidata.org/wiki/Q1128050', 'display_name': 'Hematopoietic stem cell transplantation', 'level': 3, 'score': 0.64490503}, {'id': 'https://openalex.org/C2911091166', 'wikidata': 'https://www.wikidata.org/wiki/Q106419912', 'display_name': 'Transplantation', 'level': 2, 'score': 0.6193323}, {'id': 'https://openalex.org/C2779134260', 'wikidata': 'https://www.wikidata.org/wiki/Q12136', 'display_name': 'Disease', 'level': 2, 'score': 0.60401076}, {'id': 'https://openalex.org/C3018513187', 'wikidata': 'https://www.wikidata.org/wiki/Q712378', 'display_name': 'Solid organ', 'level': 4, 'score': 0.51435983}, {'id': 'https://openalex.org/C203014093', 'wikidata': 'https://www.wikidata.org/wiki/Q101929', 'display_name': 'Immunology', 'level': 1, 'score': 0.4973705}, {'id': 'https://openalex.org/C168444539', 'wikidata': 'https://www.wikidata.org/wiki/Q105196', 'display_name': 'Organ transplantation', 'level': 3, 'score': 0.4638844}, {'id': 'https://openalex.org/C2781146716', 'wikidata': 'https://www.wikidata.org/wiki/Q1594599', 'display_name': 'Post-transplant lymphoproliferative disorder', 'level': 4, 'score': 0.43923193}, {'id': 'https://openalex.org/C2779972918', 'wikidata': 'https://www.wikidata.org/wiki/Q1194520', 'display_name': 'Graft-versus-host disease', 'level': 3, 'score': 0.42533785}, {'id': 'https://openalex.org/C2779338263', 'wikidata': 'https://www.wikidata.org/wiki/Q208414', 'display_name': 'Lymphoma', 'level': 2, 'score': 0.2724238}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.23340371}, {'id': 'https://openalex.org/C2780653079', 'wikidata': 'https://www.wikidata.org/wiki/Q412323', 'display_name': 'Rituximab', 'level': 3, 'score': 0.11746955}], 'mesh': [{'descriptor_ui': 'D018380', 'descriptor_name': 'Hematopoietic Stem Cell Transplantation', 'qualifier_ui': 'Q000009', 'qualifier_name': 'adverse effects', 'is_major_topic': True}, {'descriptor_ui': 'D016867', 'descriptor_name': 'Immunocompromised Host', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D007165', 'descriptor_name': 'Immunosuppression Therapy', 'qualifier_ui': 'Q000009', 'qualifier_name': 'adverse effects', 'is_major_topic': True}, {'descriptor_ui': 'D008232', 'descriptor_name': 'Lymphoproliferative Disorders', 'qualifier_ui': 'Q000209', 'qualifier_name': 'etiology', 'is_major_topic': True}, {'descriptor_ui': 'D016377', 'descriptor_name': 'Organ Transplantation', 'qualifier_ui': 'Q000009', 'qualifier_name': 'adverse effects', 'is_major_topic': True}, {'descriptor_ui': 'D000328', 'descriptor_name': 'Adult', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D020031', 'descriptor_name': 'Epstein-Barr Virus Infections', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D020031', 'descriptor_name': 'Epstein-Barr Virus Infections', 'qualifier_ui': 'Q000150', 'qualifier_name': 'complications', 'is_major_topic': False}, {'descriptor_ui': 'D018380', 'descriptor_name': 'Hematopoietic Stem Cell Transplantation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007155', 'descriptor_name': 'Immunologic Factors', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007155', 'descriptor_name': 'Immunologic Factors', 'qualifier_ui': 'Q000627', 'qualifier_name': 'therapeutic use', 'is_major_topic': False}, {'descriptor_ui': 'D007165', 'descriptor_name': 'Immunosuppression Therapy', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007167', 'descriptor_name': 'Immunotherapy', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008232', 'descriptor_name': 'Lymphoproliferative Disorders', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008232', 'descriptor_name': 'Lymphoproliferative Disorders', 'qualifier_ui': 'Q000175', 'qualifier_name': 'diagnosis', 'is_major_topic': False}, {'descriptor_ui': 'D008232', 'descriptor_name': 'Lymphoproliferative Disorders', 'qualifier_ui': 'Q000453', 'qualifier_name': 'epidemiology', 'is_major_topic': False}, {'descriptor_ui': 'D008232', 'descriptor_name': 'Lymphoproliferative Disorders', 'qualifier_ui': 'Q000628', 'qualifier_name': 'therapy', 'is_major_topic': False}, {'descriptor_ui': 'D016377', 'descriptor_name': 'Organ Transplantation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011379', 'descriptor_name': 'Prognosis', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D012307', 'descriptor_name': 'Risk Factors', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000069283', 'descriptor_name': 'Rituximab', 'qualifier_ui': 'Q000627', 'qualifier_name': 'therapeutic use', 'is_major_topic': False}, {'descriptor_ui': 'D000069283', 'descriptor_name': 'Rituximab', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D014184', 'descriptor_name': 'Transplantation, Homologous', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1056/nejmra1702693', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S62468778', 'display_name': 'New England Journal of Medicine', 'issn_l': '0028-4793', 'issn': ['0028-4793', '1533-4406'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320239', 'host_organization_name': 'Massachusetts Medical Society', 'host_organization_lineage': ['https://openalex.org/P4310320239'], 'host_organization_lineage_names': ['Massachusetts Medical Society'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/29414277', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'score': 0.68, 'id': 'https://metadata.un.org/sdg/2', 'display_name': 'Zero hunger'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 83, 'referenced_works': ['https://openalex.org/W1510797800', 'https://openalex.org/W1543833158', 'https://openalex.org/W1544269146', 'https://openalex.org/W1549927326', 'https://openalex.org/W1572459595', 'https://openalex.org/W1593469847', 'https://openalex.org/W1696276358', 'https://openalex.org/W1786008440', 'https://openalex.org/W1907736995', 'https://openalex.org/W1925602349', 'https://openalex.org/W1964106115', 'https://openalex.org/W1968111008', 'https://openalex.org/W1977635228', 'https://openalex.org/W1979401674', 'https://openalex.org/W1985222393', 'https://openalex.org/W1985970373', 'https://openalex.org/W1989488484', 'https://openalex.org/W1993281387', 'https://openalex.org/W1993504721', 'https://openalex.org/W1994080024', 'https://openalex.org/W1996729395', 'https://openalex.org/W2007193673', 'https://openalex.org/W2007367871', 'https://openalex.org/W2009628438', 'https://openalex.org/W2012103600', 'https://openalex.org/W2015278968', 'https://openalex.org/W2017201945', 'https://openalex.org/W2018175302', 'https://openalex.org/W2024382442', 'https://openalex.org/W2026571203', 'https://openalex.org/W2027948008', 'https://openalex.org/W2031832264', 'https://openalex.org/W2037796411', 'https://openalex.org/W2042326030', 'https://openalex.org/W2048288179', 'https://openalex.org/W2054279695', 'https://openalex.org/W2055375238', 'https://openalex.org/W2059793178', 'https://openalex.org/W2061446569', 'https://openalex.org/W2075432289', 'https://openalex.org/W2085600578', 'https://openalex.org/W2089923210', 'https://openalex.org/W2091616383', 'https://openalex.org/W2092415681', 'https://openalex.org/W2096644943', 'https://openalex.org/W2099112994', 'https://openalex.org/W2115042515', 'https://openalex.org/W2117287242', 'https://openalex.org/W2125231116', 'https://openalex.org/W2128732540', 'https://openalex.org/W2139241553', 'https://openalex.org/W2144718251', 'https://openalex.org/W2147246240', 'https://openalex.org/W2148422519', 'https://openalex.org/W2151139118', 'https://openalex.org/W2157666918', 'https://openalex.org/W2158267770', 'https://openalex.org/W2163510698', 'https://openalex.org/W2168772082', 'https://openalex.org/W2170308172', 'https://openalex.org/W2171321148', 'https://openalex.org/W2225072291', 'https://openalex.org/W2235523093', 'https://openalex.org/W2272544270', 'https://openalex.org/W2290253528', 'https://openalex.org/W2295409074', 'https://openalex.org/W2310716991', 'https://openalex.org/W2326233113', 'https://openalex.org/W2338402453', 'https://openalex.org/W2339783666', 'https://openalex.org/W2400770462', 'https://openalex.org/W2410125030', 'https://openalex.org/W2465355173', 'https://openalex.org/W2493435663', 'https://openalex.org/W2495196452', 'https://openalex.org/W2514437839', 'https://openalex.org/W2519323155', 'https://openalex.org/W2569045496', 'https://openalex.org/W2578082697', 'https://openalex.org/W2578876390', 'https://openalex.org/W2605534519', 'https://openalex.org/W2747457204', 'https://openalex.org/W4205736005'], 'related_works': ['https://openalex.org/W4312350884', 'https://openalex.org/W4200516431', 'https://openalex.org/W3008063367', 'https://openalex.org/W2737030275', 'https://openalex.org/W2322969100', 'https://openalex.org/W2157666918', 'https://openalex.org/W2156902794', 'https://openalex.org/W2071705083', 'https://openalex.org/W2032091237', 'https://openalex.org/W2008857130'], 'abstract_inverted_index': {'Solid-organ': [0], 'and': [1, 17, 23], 'hematopoietic': [2], 'stem-cell': [3], 'transplants': [4], 'are': [5], 'widely': [6], 'used': [7], 'for': [8], 'various': [9], 'life-threatening': [10], 'medical': [11], 'disorders.': [12], 'Prophylaxis': [13], 'against': [14], 'transplant': [15], 'rejection': [16], 'graft-versus-host': [18], 'disease': [19], 'is': [20], 'often': [21], 'immunosuppressive': [22], 'can': [24], 'increase': [25], 'the': [26], 'risk': [27], 'of': [28], 'lymphoproliferative': [29], 'disease.': [30]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2786571997', 'counts_by_year': [{'year': 2024, 'cited_by_count': 47}, {'year': 2023, 'cited_by_count': 51}, {'year': 2022, 'cited_by_count': 55}, {'year': 2021, 'cited_by_count': 82}, {'year': 2020, 'cited_by_count': 56}, {'year': 2019, 'cited_by_count': 45}, {'year': 2018, 'cited_by_count': 15}], 'updated_date': '2024-12-26T15:29:06.859795', 'created_date': '2018-02-23'}
Publication Information

Basic Information

Access and Citation

AI Researcher Chatbot

Primary Location

Authors

Topics

Keywords

Related Works
