Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W277808712', 'doi': 'https://doi.org/10.1007/s11010-015-2448-5', 'title': 'Arginase I expression is upregulated by dietary restriction in the liver of mice as a function of age', 'display_name': 'Arginase I expression is upregulated by dietary restriction in the liver of mice as a function of age', 'publication_year': 2015, 'publication_date': '2015-05-15', 'ids': {'openalex': 'https://openalex.org/W277808712', 'doi': 'https://doi.org/10.1007/s11010-015-2448-5', 'mag': '277808712', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/25976668'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1007/s11010-015-2448-5', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S11742566', 'display_name': 'Molecular and Cellular Biochemistry', 'issn_l': '0300-8177', 'issn': ['0300-8177', '1573-4919'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310319900', 'host_organization_name': 'Springer Science+Business Media', 'host_organization_lineage': ['https://openalex.org/P4310319965', 'https://openalex.org/P4310319900'], 'host_organization_lineage_names': ['Springer Nature', 'Springer Science+Business Media'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5005124620', 'display_name': 'Teikur Majaw', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I197465736', 'display_name': 'North Eastern Hill University', 'ror': 'https://ror.org/055m2tx54', 'country_code': 'IN', 'type': 'education', 'lineage': ['https://openalex.org/I197465736']}], 'countries': ['IN'], 'is_corresponding': False, 'raw_author_name': 'Teikur Majaw', 'raw_affiliation_strings': ['Department of Biochemistry, North-Eastern Hill University, Shillong, 793 022, India'], 'affiliations': [{'raw_affiliation_string': 'Department of Biochemistry, North-Eastern Hill University, Shillong, 793 022, India', 'institution_ids': ['https://openalex.org/I197465736']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5027802945', 'display_name': 'Ramesh Sharma', 'orcid': 'https://orcid.org/0000-0002-1574-8930'}, 'institutions': [{'id': 'https://openalex.org/I197465736', 'display_name': 'North Eastern Hill University', 'ror': 'https://ror.org/055m2tx54', 'country_code': 'IN', 'type': 'education', 'lineage': ['https://openalex.org/I197465736']}], 'countries': ['IN'], 'is_corresponding': False, 'raw_author_name': 'Ramesh Sharma', 'raw_affiliation_strings': ['Department of Biochemistry, North-Eastern Hill University, Shillong, 793 022, India'], 'affiliations': [{'raw_affiliation_string': 'Department of Biochemistry, North-Eastern Hill University, Shillong, 793 022, India', 'institution_ids': ['https://openalex.org/I197465736']}]}], 'countries_distinct_count': 1, 'institutions_distinct_count': 1, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 1.066, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 10, 'citation_normalized_percentile': {'value': 0.646844, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 86, 'max': 87}, 'biblio': {'volume': '407', 'issue': '1-2', 'first_page': '1', 'last_page': '7'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T12770', 'display_name': 'Amino Acid Transport and Metabolism in Health and Disease', 'score': 0.9992, 'subfield': {'id': 'https://openalex.org/subfields/1303', 'display_name': 'Biochemistry'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T12770', 'display_name': 'Amino Acid Transport and Metabolism in Health and Disease', 'score': 0.9992, 'subfield': {'id': 'https://openalex.org/subfields/1303', 'display_name': 'Biochemistry'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T11027', 'display_name': 'Metabolic Disorders and Biochemical Genetics', 'score': 0.9974, 'subfield': {'id': 'https://openalex.org/subfields/1308', 'display_name': 'Clinical Biochemistry'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T11337', 'display_name': 'Neuroimmune Interaction in Psychiatric Disorders', 'score': 0.9965, 'subfield': {'id': 'https://openalex.org/subfields/2803', 'display_name': 'Biological Psychiatry'}, 'field': {'id': 'https://openalex.org/fields/28', 'display_name': 'Neuroscience'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/catabolism', 'display_name': 'Catabolism', 'score': 0.51112896}, {'id': 'https://openalex.org/keywords/ornithine-aminotransferase', 'display_name': 'Ornithine aminotransferase', 'score': 0.44432366}, {'id': 'https://openalex.org/keywords/immune-activation', 'display_name': 'Immune Activation', 'score': 0.440959}], 'concepts': [{'id': 'https://openalex.org/C164007495', 'wikidata': 'https://www.wikidata.org/wiki/Q24721374', 'display_name': 'Arginase', 'level': 4, 'score': 0.9981855}, {'id': 'https://openalex.org/C2776796294', 'wikidata': 'https://www.wikidata.org/wiki/Q410198', 'display_name': 'Ornithine', 'level': 4, 'score': 0.65384626}, {'id': 'https://openalex.org/C77061444', 'wikidata': 'https://www.wikidata.org/wiki/Q595994', 'display_name': 'Urea cycle', 'level': 4, 'score': 0.6410614}, {'id': 'https://openalex.org/C127561419', 'wikidata': 'https://www.wikidata.org/wiki/Q224527', 'display_name': 'Downregulation and upregulation', 'level': 3, 'score': 0.54734474}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.5422436}, {'id': 'https://openalex.org/C134018914', 'wikidata': 'https://www.wikidata.org/wiki/Q162606', 'display_name': 'Endocrinology', 'level': 1, 'score': 0.5339709}, {'id': 'https://openalex.org/C96942376', 'wikidata': 'https://www.wikidata.org/wiki/Q21130714', 'display_name': 'Catabolism', 'level': 3, 'score': 0.51112896}, {'id': 'https://openalex.org/C2777468819', 'wikidata': 'https://www.wikidata.org/wiki/Q173670', 'display_name': 'Arginine', 'level': 3, 'score': 0.44806588}, {'id': 'https://openalex.org/C2781017228', 'wikidata': 'https://www.wikidata.org/wiki/Q7103622', 'display_name': 'Ornithine aminotransferase', 'level': 5, 'score': 0.44432366}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.4241036}, {'id': 'https://openalex.org/C2780365088', 'wikidata': 'https://www.wikidata.org/wiki/Q48318', 'display_name': 'Urea', 'level': 2, 'score': 0.41831952}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.40360543}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.31334835}, {'id': 'https://openalex.org/C62231903', 'wikidata': 'https://www.wikidata.org/wiki/Q1057', 'display_name': 'Metabolism', 'level': 2, 'score': 0.24060795}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.18639874}, {'id': 'https://openalex.org/C515207424', 'wikidata': 'https://www.wikidata.org/wiki/Q8066', 'display_name': 'Amino acid', 'level': 2, 'score': 0.09276742}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.07116482}], 'mesh': [{'descriptor_ui': 'D000375', 'descriptor_name': 'Aging', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D001119', 'descriptor_name': 'Arginase', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D004032', 'descriptor_name': 'Diet', 'qualifier_ui': 'Q000009', 'qualifier_name': 'adverse effects', 'is_major_topic': True}, {'descriptor_ui': 'D008099', 'descriptor_name': 'Liver', 'qualifier_ui': 'Q000201', 'qualifier_name': 'enzymology', 'is_major_topic': True}, {'descriptor_ui': 'D000375', 'descriptor_name': 'Aging', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001119', 'descriptor_name': 'Arginase', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001119', 'descriptor_name': 'Arginase', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D004032', 'descriptor_name': 'Diet', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004032', 'descriptor_name': 'Diet', 'qualifier_ui': 'Q000379', 'qualifier_name': 'methods', 'is_major_topic': False}, {'descriptor_ui': 'D015971', 'descriptor_name': 'Gene Expression Regulation, Enzymologic', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008099', 'descriptor_name': 'Liver', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008297', 'descriptor_name': 'Male', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D051379', 'descriptor_name': 'Mice', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015854', 'descriptor_name': 'Up-Regulation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1007/s11010-015-2448-5', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S11742566', 'display_name': 'Molecular and Cellular Biochemistry', 'issn_l': '0300-8177', 'issn': ['0300-8177', '1573-4919'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310319900', 'host_organization_name': 'Springer Science+Business Media', 'host_organization_lineage': ['https://openalex.org/P4310319965', 'https://openalex.org/P4310319900'], 'host_organization_lineage_names': ['Springer Nature', 'Springer Science+Business Media'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/25976668', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'id': 'https://metadata.un.org/sdg/2', 'display_name': 'Zero hunger', 'score': 0.84}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 41, 'referenced_works': ['https://openalex.org/W1436528600', 'https://openalex.org/W1581040284', 'https://openalex.org/W1590474280', 'https://openalex.org/W1602715853', 'https://openalex.org/W1611000773', 'https://openalex.org/W1901983160', 'https://openalex.org/W1956327946', 'https://openalex.org/W1964184380', 'https://openalex.org/W1964299219', 'https://openalex.org/W1968475125', 'https://openalex.org/W1980077908', 'https://openalex.org/W1987881651', 'https://openalex.org/W1993044841', 'https://openalex.org/W2021569259', 'https://openalex.org/W2033119372', 'https://openalex.org/W2040381357', 'https://openalex.org/W2056335897', 'https://openalex.org/W2058737138', 'https://openalex.org/W2070809007', 'https://openalex.org/W2079245468', 'https://openalex.org/W2081656733', 'https://openalex.org/W2084097442', 'https://openalex.org/W2085447674', 'https://openalex.org/W2093495014', 'https://openalex.org/W2105685838', 'https://openalex.org/W2107277218', 'https://openalex.org/W2108290804', 'https://openalex.org/W2121945497', 'https://openalex.org/W2122620803', 'https://openalex.org/W2126525177', 'https://openalex.org/W2128329787', 'https://openalex.org/W2128635872', 'https://openalex.org/W2144651567', 'https://openalex.org/W2178289462', 'https://openalex.org/W2318530848', 'https://openalex.org/W2417262350', 'https://openalex.org/W2419604885', 'https://openalex.org/W2439708677', 'https://openalex.org/W4242761677', 'https://openalex.org/W4285719527', 'https://openalex.org/W4293247451'], 'related_works': ['https://openalex.org/W9195784', 'https://openalex.org/W3176037224', 'https://openalex.org/W2401817542', 'https://openalex.org/W2339349566', 'https://openalex.org/W2324336404', 'https://openalex.org/W2152768879', 'https://openalex.org/W2125573269', 'https://openalex.org/W2114655432', 'https://openalex.org/W2105100270', 'https://openalex.org/W1897049332'], 'abstract_inverted_index': None, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W277808712', 'counts_by_year': [{'year': 2024, 'cited_by_count': 1}, {'year': 2020, 'cited_by_count': 1}, {'year': 2019, 'cited_by_count': 1}, {'year': 2018, 'cited_by_count': 1}, {'year': 2017, 'cited_by_count': 3}, {'year': 2016, 'cited_by_count': 3}], 'updated_date': '2024-09-10T17:12:40.640083', 'created_date': '2016-06-24'}