Abstract: Serum AMH (anti-Müllerian hormone) is the latest marker for the assessment of the ovarian reserve in women. It is synthetized by small antral follicles, which are precisely the ones counted on ultrasound for the antral follicle count (AFC). Serum AMH can therefore be used as a surrogate to the AFC in the evaluation of the ovarian reserve. The assessment of the ovarian reserve has become a useful tool in the prediction of fertility. More and more women inquire to know their ovarian reserve, in order to plan their pregnancies. However, it is a dangerous shortcut because neither serum AMH nor the AFC can predict the chances of spontaneous pregnancy. A low or a high ovarian reserve could therefore mislead a woman about her capacity to get pregnant. This review will explain the physiology of AMH and the difficulties of its different assays. We will also demonstrate the utility of AMH in the assessment of the ovarian reserve and more especially in its pathology (ovarian damage, polycystic ovarian syndrome), and in the prediction of the time of menopause. Finally, we will review the utility of serum AMH in the different treatments of infertility.
Publication Year: 2019
Publication Date: 2019-01-01
Language: en
Type: book-chapter
Indexed In: ['crossref']
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