Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2773200456', 'doi': 'https://doi.org/10.1016/j.bbrc.2017.12.067', 'title': 'Aberrant alternative splicing of RHOA is associated with loss of its expression and activity in diffuse-type gastric carcinoma cells', 'display_name': 'Aberrant alternative splicing of RHOA is associated with loss of its expression and activity in diffuse-type gastric carcinoma cells', 'publication_year': 2018, 'publication_date': '2018-01-01', 'ids': {'openalex': 'https://openalex.org/W2773200456', 'doi': 'https://doi.org/10.1016/j.bbrc.2017.12.067', 'mag': '2773200456', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/29247652'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1016/j.bbrc.2017.12.067', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S151589183', 'display_name': 'Biochemical and Biophysical Research Communications', 'issn_l': '0006-291X', 'issn': ['0006-291X', '1090-2104'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5102721166', 'display_name': 'Shingo Miyamoto', 'orcid': 'https://orcid.org/0000-0002-2782-4240'}, 'institutions': [{'id': 'https://openalex.org/I2802207800', 'display_name': 'Sasaki Institute', 'ror': 'https://ror.org/016chgx50', 'country_code': 'JP', 'type': 'nonprofit', 'lineage': ['https://openalex.org/I2802207800']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Shingo Miyamoto', 'raw_affiliation_strings': ['Department of Cancer Cell Research, Sasaki Institute, Sasaki Foundation, 2-2 Kandasurugadai, Chiyoda-ku, Tokyo 101-0062, Japan'], 'affiliations': [{'raw_affiliation_string': 'Department of Cancer Cell Research, Sasaki Institute, Sasaki Foundation, 2-2 Kandasurugadai, Chiyoda-ku, Tokyo 101-0062, Japan', 'institution_ids': ['https://openalex.org/I2802207800']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5029877725', 'display_name': 'Yuko Nagamura', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I2802207800', 'display_name': 'Sasaki Institute', 'ror': 'https://ror.org/016chgx50', 'country_code': 'JP', 'type': 'nonprofit', 'lineage': ['https://openalex.org/I2802207800']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Yuko Nagamura', 'raw_affiliation_strings': ['Department of Cancer Cell Research, Sasaki Institute, Sasaki Foundation, 2-2 Kandasurugadai, Chiyoda-ku, Tokyo 101-0062, Japan'], 'affiliations': [{'raw_affiliation_string': 'Department of Cancer Cell Research, Sasaki Institute, Sasaki Foundation, 2-2 Kandasurugadai, Chiyoda-ku, Tokyo 101-0062, Japan', 'institution_ids': ['https://openalex.org/I2802207800']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5084833665', 'display_name': 'Ayaka Nakabo', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I2802207800', 'display_name': 'Sasaki Institute', 'ror': 'https://ror.org/016chgx50', 'country_code': 'JP', 'type': 'nonprofit', 'lineage': ['https://openalex.org/I2802207800']}, {'id': 'https://openalex.org/I149964584', 'display_name': 'Tokyo University of Pharmacy and Life Sciences', 'ror': 'https://ror.org/057jm7w82', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I149964584']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Ayaka Nakabo', 'raw_affiliation_strings': ['Department of Cancer Cell Research, Sasaki Institute, Sasaki Foundation, 2-2 Kandasurugadai, Chiyoda-ku, Tokyo 101-0062, Japan', 'Laboratory of Genome and Biosignal, Tokyo University of Pharmacy and Life Sciences, 1432-1 Horinouchi, Hachioji-shi, Tokyo 192-0392, Japan'], 'affiliations': [{'raw_affiliation_string': 'Department of Cancer Cell Research, Sasaki Institute, Sasaki Foundation, 2-2 Kandasurugadai, Chiyoda-ku, Tokyo 101-0062, Japan', 'institution_ids': ['https://openalex.org/I2802207800']}, {'raw_affiliation_string': 'Laboratory of Genome and Biosignal, Tokyo University of Pharmacy and Life Sciences, 1432-1 Horinouchi, Hachioji-shi, Tokyo 192-0392, Japan', 'institution_ids': ['https://openalex.org/I149964584']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5083207864', 'display_name': 'Atsuyuki Okabe', 'orcid': 'https://orcid.org/0000-0003-4663-8053'}, 'institutions': [{'id': 'https://openalex.org/I149964584', 'display_name': 'Tokyo University of Pharmacy and Life Sciences', 'ror': 'https://ror.org/057jm7w82', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I149964584']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Akira Okabe', 'raw_affiliation_strings': ['Laboratory of Genome and Biosignal, Tokyo University of Pharmacy and Life Sciences, 1432-1 Horinouchi, Hachioji-shi, Tokyo 192-0392, Japan'], 'affiliations': [{'raw_affiliation_string': 'Laboratory of Genome and Biosignal, Tokyo University of Pharmacy and Life Sciences, 1432-1 Horinouchi, Hachioji-shi, Tokyo 192-0392, Japan', 'institution_ids': ['https://openalex.org/I149964584']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5053041120', 'display_name': 'Kazuyoshi Yanagihara', 'orcid': None}, 'institutions': [], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Kazuyoshi Yanagihara', 'raw_affiliation_strings': ['Division of Biomarker Discovery, Exploratory Oncology & Clinical Trial Center, National Cancer Center, 6-5-1 Kashiwanoha, Kashiwa, Chiba 277-8577, Japan'], 'affiliations': [{'raw_affiliation_string': 'Division of Biomarker Discovery, Exploratory Oncology & Clinical Trial Center, National Cancer Center, 6-5-1 Kashiwanoha, Kashiwa, Chiba 277-8577, Japan', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5105409269', 'display_name': 'Kiyoko Fukami', 'orcid': 'https://orcid.org/0000-0003-3205-1542'}, 'institutions': [{'id': 'https://openalex.org/I149964584', 'display_name': 'Tokyo University of Pharmacy and Life Sciences', 'ror': 'https://ror.org/057jm7w82', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I149964584']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Kiyoko Fukami', 'raw_affiliation_strings': ['Laboratory of Genome and Biosignal, Tokyo University of Pharmacy and Life Sciences, 1432-1 Horinouchi, Hachioji-shi, Tokyo 192-0392, Japan'], 'affiliations': [{'raw_affiliation_string': 'Laboratory of Genome and Biosignal, Tokyo University of Pharmacy and Life Sciences, 1432-1 Horinouchi, Hachioji-shi, Tokyo 192-0392, Japan', 'institution_ids': ['https://openalex.org/I149964584']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5076707760', 'display_name': 'Ryuichi Sakai', 'orcid': 'https://orcid.org/0000-0001-6833-1103'}, 'institutions': [{'id': 'https://openalex.org/I64189623', 'display_name': 'Kitasato University', 'ror': 'https://ror.org/00f2txz25', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I64189623']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Ryuichi Sakai', 'raw_affiliation_strings': ['Department of Biochemistry, Kitasato University School of Medicine, 1-15-1 Kitasato, Minami-ku, Sagamihara, Kanagawa 252-0374, Japan'], 'affiliations': [{'raw_affiliation_string': 'Department of Biochemistry, Kitasato University School of Medicine, 1-15-1 Kitasato, Minami-ku, Sagamihara, Kanagawa 252-0374, Japan', 'institution_ids': ['https://openalex.org/I64189623']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5003421949', 'display_name': 'Hideki Yamaguchi', 'orcid': 'https://orcid.org/0000-0003-2125-9655'}, 'institutions': [{'id': 'https://openalex.org/I2802207800', 'display_name': 'Sasaki Institute', 'ror': 'https://ror.org/016chgx50', 'country_code': 'JP', 'type': 'nonprofit', 'lineage': ['https://openalex.org/I2802207800']}], 'countries': ['JP'], 'is_corresponding': True, 'raw_author_name': 'Hideki Yamaguchi', 'raw_affiliation_strings': ['Department of Cancer Cell Research, Sasaki Institute, Sasaki Foundation, 2-2 Kandasurugadai, Chiyoda-ku, Tokyo 101-0062, Japan'], 'affiliations': [{'raw_affiliation_string': 'Department of Cancer Cell Research, Sasaki Institute, Sasaki Foundation, 2-2 Kandasurugadai, Chiyoda-ku, Tokyo 101-0062, Japan', 'institution_ids': ['https://openalex.org/I2802207800']}]}], 'countries_distinct_count': 1, 'institutions_distinct_count': 3, 'corresponding_author_ids': ['https://openalex.org/A5003421949'], 'corresponding_institution_ids': ['https://openalex.org/I2802207800'], 'apc_list': {'value': 2770, 'currency': 'USD', 'value_usd': 2770, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 0.457, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 8, 'citation_normalized_percentile': {'value': 0.671968, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 84, 'max': 85}, 'biblio': {'volume': '495', 'issue': '2', 'first_page': '1942', 'last_page': '1947'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10604', 'display_name': 'Regulation of RNA Processing and Function', 'score': 0.9991, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10604', 'display_name': 'Regulation of RNA Processing and Function', 'score': 0.9991, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T11482', 'display_name': 'RNA Methylation and Modification in Gene Expression', 'score': 0.9965, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T11369', 'display_name': 'Molecular Characterization of Colorectal Cancer', 'score': 0.9964, 'subfield': {'id': 'https://openalex.org/subfields/2734', 'display_name': 'Pathology and Forensic Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/alternative-splicing', 'display_name': 'Alternative Splicing', 'score': 0.508571}], 'concepts': [{'id': 'https://openalex.org/C2777093181', 'wikidata': 'https://www.wikidata.org/wiki/Q15331450', 'display_name': 'RHOA', 'level': 3, 'score': 0.9969684}, {'id': 'https://openalex.org/C194583182', 'wikidata': 'https://www.wikidata.org/wiki/Q21114084', 'display_name': 'Alternative splicing', 'level': 4, 'score': 0.75086933}, {'id': 'https://openalex.org/C54458228', 'wikidata': 'https://www.wikidata.org/wiki/Q237218', 'display_name': 'RNA splicing', 'level': 4, 'score': 0.65570533}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.58531135}, {'id': 'https://openalex.org/C153911025', 'wikidata': 'https://www.wikidata.org/wiki/Q7202', 'display_name': 'Molecular biology', 'level': 1, 'score': 0.4867692}, {'id': 'https://openalex.org/C53345823', 'wikidata': 'https://www.wikidata.org/wiki/Q5531554', 'display_name': 'Gene isoform', 'level': 3, 'score': 0.4634305}, {'id': 'https://openalex.org/C207332259', 'wikidata': 'https://www.wikidata.org/wiki/Q769143', 'display_name': 'GTPase', 'level': 2, 'score': 0.44628686}, {'id': 'https://openalex.org/C81885089', 'wikidata': 'https://www.wikidata.org/wiki/Q189082', 'display_name': 'Cell culture', 'level': 2, 'score': 0.43801364}, {'id': 'https://openalex.org/C95444343', 'wikidata': 'https://www.wikidata.org/wiki/Q7141', 'display_name': 'Cell biology', 'level': 1, 'score': 0.403939}, {'id': 'https://openalex.org/C502942594', 'wikidata': 'https://www.wikidata.org/wiki/Q3421914', 'display_name': 'Cancer research', 'level': 1, 'score': 0.381434}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.24658012}, {'id': 'https://openalex.org/C54355233', 'wikidata': 'https://www.wikidata.org/wiki/Q7162', 'display_name': 'Genetics', 'level': 1, 'score': 0.23441112}, {'id': 'https://openalex.org/C62478195', 'wikidata': 'https://www.wikidata.org/wiki/Q828130', 'display_name': 'Signal transduction', 'level': 2, 'score': 0.16523394}, {'id': 'https://openalex.org/C67705224', 'wikidata': 'https://www.wikidata.org/wiki/Q11053', 'display_name': 'RNA', 'level': 3, 'score': 0.06726551}], 'mesh': [{'descriptor_ui': 'D017398', 'descriptor_name': 'Alternative Splicing', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': True}, {'descriptor_ui': 'D015972', 'descriptor_name': 'Gene Expression Regulation, Neoplastic', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': True}, {'descriptor_ui': 'D020033', 'descriptor_name': 'Protein Isoforms', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': True}, {'descriptor_ui': 'D013274', 'descriptor_name': 'Stomach Neoplasms', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': True}, {'descriptor_ui': 'D013274', 'descriptor_name': 'Stomach Neoplasms', 'qualifier_ui': 'Q000201', 'qualifier_name': 'enzymology', 'is_major_topic': True}, {'descriptor_ui': 'D020742', 'descriptor_name': 'rhoA GTP-Binding Protein', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': True}, {'descriptor_ui': 'D017398', 'descriptor_name': 'Alternative Splicing', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D045744', 'descriptor_name': 'Cell Line, Tumor', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004789', 'descriptor_name': 'Enzyme Activation', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D004789', 'descriptor_name': 'Enzyme Activation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015972', 'descriptor_name': 'Gene Expression Regulation, Neoplastic', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009154', 'descriptor_name': 'Mutation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009154', 'descriptor_name': 'Mutation', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D020033', 'descriptor_name': 'Protein Isoforms', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013274', 'descriptor_name': 'Stomach Neoplasms', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D020742', 'descriptor_name': 'rhoA GTP-Binding Protein', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1016/j.bbrc.2017.12.067', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S151589183', 'display_name': 'Biochemical and Biophysical Research Communications', 'issn_l': '0006-291X', 'issn': ['0006-291X', '1090-2104'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/29247652', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [], 'grants': [{'funder': 'https://openalex.org/F4320309807', 'funder_display_name': 'Takeda Science Foundation', 'award_id': None}, {'funder': 'https://openalex.org/F4320334764', 'funder_display_name': 'Japan Society for the Promotion of Science', 'award_id': 'JP16K14622'}, {'funder': 'https://openalex.org/F4320334764', 'funder_display_name': 'Japan Society for the Promotion of Science', 'award_id': 'JP25430126'}], 'datasets': [], 'versions': [], 'referenced_works_count': 27, 'referenced_works': ['https://openalex.org/W1627528893', 'https://openalex.org/W1739919543', 'https://openalex.org/W1832912525', 'https://openalex.org/W1883773314', 'https://openalex.org/W1965619419', 'https://openalex.org/W1970177546', 'https://openalex.org/W2007490905', 'https://openalex.org/W2019731805', 'https://openalex.org/W2037513661', 'https://openalex.org/W2045690932', 'https://openalex.org/W2046987206', 'https://openalex.org/W2052744621', 'https://openalex.org/W2054994176', 'https://openalex.org/W2069271377', 'https://openalex.org/W2071199281', 'https://openalex.org/W2075256713', 'https://openalex.org/W2114031931', 'https://openalex.org/W2114096478', 'https://openalex.org/W2126547130', 'https://openalex.org/W2136818310', 'https://openalex.org/W2146146853', 'https://openalex.org/W2157936723', 'https://openalex.org/W2338576041', 'https://openalex.org/W2385313902', 'https://openalex.org/W2562016372', 'https://openalex.org/W2902200003', 'https://openalex.org/W4233431843'], 'related_works': ['https://openalex.org/W4385462331', 'https://openalex.org/W4213427798', 'https://openalex.org/W2904939684', 'https://openalex.org/W2797310082', 'https://openalex.org/W2321791250', 'https://openalex.org/W2090969926', 'https://openalex.org/W2081598294', 'https://openalex.org/W2024546609', 'https://openalex.org/W2023199111', 'https://openalex.org/W2012312817'], 'abstract_inverted_index': {'RhoA': [0, 69, 155], 'is': [1, 33], 'a': [2, 34, 49], 'member': [3], 'of': [4, 23, 36, 46, 51, 68, 96, 111, 134, 154, 176, 182], 'Rho': [5], 'family': [6], 'small': [7], 'GTPases': [8], 'that': [9, 31, 63, 92, 108, 172], 'regulates': [10], 'diverse': [11], 'cellular': [12], 'functions.': [13], 'Recent': [14], 'large-scale': [15], 'sequencing': [16, 90], 'studies': [17], 'have': [18], 'identified': [19], 'recurrent': [20], 'somatic': [21], 'mutations': [22], 'RHOA': [24, 32, 47, 87, 97, 113, 135, 177], 'in': [25, 48, 72, 99, 124, 167, 179, 187], 'diffuse-type': [26], 'gastric': [27, 52], 'carcinoma': [28, 53], '(DGC),': [29], 'indicating': [30], 'driver': [35], 'DGC.': [37], 'In': [38], 'this': [39], 'study,': [40], 'we': [41], 'investigated': [42], 'the': [43, 64, 109, 131, 142, 151, 180], 'possible': [44], 'abnormalities': [45], 'panel': [50], '(GC)': [54], 'cell': [55, 75, 82, 101, 128], 'lines.': [56, 102, 129], 'Pulldown': [57], 'assay': [58], 'and': [59, 66, 85, 126, 141, 185], 'immunoblot': [60], 'analysis': [61, 106], 'showed': [62, 107], 'activity': [65, 184], 'expression': [67, 110, 132, 186], 'were': [70, 120, 138, 145, 157], 'detectable': [71], 'all': [73], 'GC': [74], 'lines': [76], 'tested,': [77], 'except': [78], 'for': [79], 'two': [80], 'DGC': [81, 188], 'lines,': [83], 'HSC-59': [84, 125], 'GSU.': [86], 'coding': [88], 'region': [89], 'revealed': [91], 'aberrant': [93, 173], 'alternative': [94, 174], 'splicing': [95, 118, 136, 152, 175], 'occurred': [98], 'these': [100], 'Quantitative': [103], 'real-time': [104], 'PCR': [105], 'wild-type': [112], 'was': [114], 'nearly': [115], 'undetectable,': [116], 'whereas': [117], 'variants': [119, 137], 'almost': [121], 'exclusively': [122], 'expressed': [123, 160, 166], 'GSU': [127], 'However,': [130], 'levels': [133], 'very': [139], 'low': [140], 'corresponding': [143], 'proteins': [144], 'not': [146], 'detected': [147], 'by': [148], 'immunoblotting.': [149], 'Moreover,': [150], 'isoforms': [153], 'protein': [156], 'neither': [158], 'efficiently': [159], 'nor': [161], 'activated': [162], 'even': [163], 'if': [164], 'ectopically': [165], 'cells.': [168, 189], 'These': [169], 'results': [170, 178], 'indicate': [171], 'loss': [181], 'its': [183]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2773200456', 'counts_by_year': [{'year': 2022, 'cited_by_count': 3}, {'year': 2021, 'cited_by_count': 1}, {'year': 2020, 'cited_by_count': 1}, {'year': 2019, 'cited_by_count': 2}, {'year': 2018, 'cited_by_count': 1}], 'updated_date': '2024-09-13T13:31:39.771360', 'created_date': '2017-12-22'}