Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2770482307', 'doi': 'https://doi.org/10.1016/j.ijbiomac.2017.11.133', 'title': 'A novel detergent additive: Organic solvent- and thermo-alkaline-stable recombinant subtilisin', 'display_name': 'A novel detergent additive: Organic solvent- and thermo-alkaline-stable recombinant subtilisin', 'publication_year': 2017, 'publication_date': '2017-11-23', 'ids': {'openalex': 'https://openalex.org/W2770482307', 'doi': 'https://doi.org/10.1016/j.ijbiomac.2017.11.133', 'mag': '2770482307', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/29174357'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1016/j.ijbiomac.2017.11.133', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S83853393', 'display_name': 'International Journal of Biological Macromolecules', 'issn_l': '0141-8130', 'issn': ['0141-8130', '1879-0003'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5071788227', 'display_name': 'Canan Gülmez', 'orcid': 'https://orcid.org/0000-0003-3253-1407'}, 'institutions': [{'id': 'https://openalex.org/I135987583', 'display_name': 'Kafkas University', 'ror': 'https://ror.org/04v302n28', 'country_code': 'TR', 'type': 'education', 'lineage': ['https://openalex.org/I135987583']}], 'countries': ['TR'], 'is_corresponding': False, 'raw_author_name': 'Canan Gulmez', 'raw_affiliation_strings': ['Department of Chemistry, Faculty of Science and Letter, Kafkas University, Kars, Turkey'], 'affiliations': [{'raw_affiliation_string': 'Department of Chemistry, Faculty of Science and Letter, Kafkas University, Kars, Turkey', 'institution_ids': ['https://openalex.org/I135987583']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5032097272', 'display_name': 'Onur Atakişi', 'orcid': 'https://orcid.org/0000-0003-1183-6076'}, 'institutions': [{'id': 'https://openalex.org/I135987583', 'display_name': 'Kafkas University', 'ror': 'https://ror.org/04v302n28', 'country_code': 'TR', 'type': 'education', 'lineage': ['https://openalex.org/I135987583']}], 'countries': ['TR'], 'is_corresponding': True, 'raw_author_name': 'Onur Atakisi', 'raw_affiliation_strings': ['Department of Chemistry, Faculty of Science and Letter, Kafkas University, Kars, Turkey'], 'affiliations': [{'raw_affiliation_string': 'Department of Chemistry, Faculty of Science and Letter, Kafkas University, Kars, Turkey', 'institution_ids': ['https://openalex.org/I135987583']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5049485659', 'display_name': 'Kezban Yıldız Dalgınlı', 'orcid': 'https://orcid.org/0000-0002-1483-348X'}, 'institutions': [{'id': 'https://openalex.org/I135987583', 'display_name': 'Kafkas University', 'ror': 'https://ror.org/04v302n28', 'country_code': 'TR', 'type': 'education', 'lineage': ['https://openalex.org/I135987583']}], 'countries': ['TR'], 'is_corresponding': False, 'raw_author_name': 'Kezban Yildiz Dalginli', 'raw_affiliation_strings': ['Department of Chemistry, Faculty of Science and Letter, Kafkas University, Kars, Turkey'], 'affiliations': [{'raw_affiliation_string': 'Department of Chemistry, Faculty of Science and Letter, Kafkas University, Kars, Turkey', 'institution_ids': ['https://openalex.org/I135987583']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5010516163', 'display_name': 'Emine Atakişi', 'orcid': 'https://orcid.org/0000-0002-5685-1870'}, 'institutions': [{'id': 'https://openalex.org/I135987583', 'display_name': 'Kafkas University', 'ror': 'https://ror.org/04v302n28', 'country_code': 'TR', 'type': 'education', 'lineage': ['https://openalex.org/I135987583']}], 'countries': ['TR'], 'is_corresponding': False, 'raw_author_name': 'Emine Atakisi', 'raw_affiliation_strings': ['Departments of Biochemistry, Faculty of Veterinary, Kafkas University, Kars, Turkey'], 'affiliations': [{'raw_affiliation_string': 'Departments of Biochemistry, Faculty of Veterinary, Kafkas University, Kars, Turkey', 'institution_ids': ['https://openalex.org/I135987583']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 1, 'corresponding_author_ids': ['https://openalex.org/A5032097272'], 'corresponding_institution_ids': ['https://openalex.org/I135987583'], 'apc_list': {'value': 4100, 'currency': 'USD', 'value_usd': 4100, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 1.409, 'has_fulltext': False, 'cited_by_count': 24, 'citation_normalized_percentile': {'value': 0.851896, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 92, 'max': 93}, 'biblio': {'volume': '108', 'issue': None, 'first_page': '436', 'last_page': '443'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T11617', 'display_name': 'Enzyme Production and Characterization', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/1305', 'display_name': 'Biotechnology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T11617', 'display_name': 'Enzyme Production and Characterization', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/1305', 'display_name': 'Biotechnology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T11124', 'display_name': 'Protein purification and stability', 'score': 0.9996, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10404', 'display_name': 'Enzyme Catalysis and Immobilization', 'score': 0.994, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/subtilisin', 'display_name': 'Subtilisin', 'score': 0.9521772}, {'id': 'https://openalex.org/keywords/nattokinase', 'display_name': 'Nattokinase', 'score': 0.6930339}, {'id': 'https://openalex.org/keywords/molecular-mass', 'display_name': 'Molecular mass', 'score': 0.5065993}], 'concepts': [{'id': 'https://openalex.org/C2779811187', 'wikidata': 'https://www.wikidata.org/wiki/Q423655', 'display_name': 'Subtilisin', 'level': 3, 'score': 0.9521772}, {'id': 'https://openalex.org/C2777807008', 'wikidata': 'https://www.wikidata.org/wiki/Q87324999', 'display_name': 'Serine protease', 'level': 4, 'score': 0.86453646}, {'id': 'https://openalex.org/C2777272437', 'wikidata': 'https://www.wikidata.org/wiki/Q131238', 'display_name': 'Bacillus subtilis', 'level': 3, 'score': 0.7169999}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.7083533}, {'id': 'https://openalex.org/C2778568395', 'wikidata': 'https://www.wikidata.org/wiki/Q11323875', 'display_name': 'Nattokinase', 'level': 3, 'score': 0.6930339}, {'id': 'https://openalex.org/C40767141', 'wikidata': 'https://www.wikidata.org/wiki/Q285697', 'display_name': 'Recombinant DNA', 'level': 3, 'score': 0.6740157}, {'id': 'https://openalex.org/C2776714187', 'wikidata': 'https://www.wikidata.org/wiki/Q212410', 'display_name': 'Protease', 'level': 3, 'score': 0.647398}, {'id': 'https://openalex.org/C43617362', 'wikidata': 'https://www.wikidata.org/wiki/Q170050', 'display_name': 'Chromatography', 'level': 1, 'score': 0.63787556}, {'id': 'https://openalex.org/C2780865716', 'wikidata': 'https://www.wikidata.org/wiki/Q411575', 'display_name': 'PMSF', 'level': 3, 'score': 0.52058107}, {'id': 'https://openalex.org/C58121356', 'wikidata': 'https://www.wikidata.org/wiki/Q182854', 'display_name': 'Molecular mass', 'level': 3, 'score': 0.5065993}, {'id': 'https://openalex.org/C181199279', 'wikidata': 'https://www.wikidata.org/wiki/Q8047', 'display_name': 'Enzyme', 'level': 2, 'score': 0.4954127}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.45716962}, {'id': 'https://openalex.org/C2780471494', 'wikidata': 'https://www.wikidata.org/wiki/Q146505', 'display_name': 'Solvent', 'level': 2, 'score': 0.45058483}, {'id': 'https://openalex.org/C179247698', 'wikidata': 'https://www.wikidata.org/wiki/Q382799', 'display_name': 'Affinity chromatography', 'level': 3, 'score': 0.44522682}, {'id': 'https://openalex.org/C2778039104', 'wikidata': 'https://www.wikidata.org/wiki/Q149088', 'display_name': 'Bacillales', 'level': 4, 'score': 0.4226908}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.15753093}, {'id': 'https://openalex.org/C523546767', 'wikidata': 'https://www.wikidata.org/wiki/Q10876', 'display_name': 'Bacteria', 'level': 2, 'score': 0.15480423}, {'id': 'https://openalex.org/C100544194', 'wikidata': 'https://www.wikidata.org/wiki/Q41760', 'display_name': 'Fermentation', 'level': 2, 'score': 0.06047845}, {'id': 'https://openalex.org/C54355233', 'wikidata': 'https://www.wikidata.org/wiki/Q7162', 'display_name': 'Genetics', 'level': 1, 'score': 0.0}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D003902', 'descriptor_name': 'Detergents', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': True}, {'descriptor_ui': 'D011994', 'descriptor_name': 'Recombinant Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D012997', 'descriptor_name': 'Solvents', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': True}, {'descriptor_ui': 'D020860', 'descriptor_name': 'Subtilisin', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': True}, {'descriptor_ui': 'D003001', 'descriptor_name': 'Cloning, Molecular', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D003902', 'descriptor_name': 'Detergents', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004789', 'descriptor_name': 'Enzyme Activation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004926', 'descriptor_name': 'Escherichia coli', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004926', 'descriptor_name': 'Escherichia coli', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D004926', 'descriptor_name': 'Escherichia coli', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D015870', 'descriptor_name': 'Gene Expression', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006863', 'descriptor_name': 'Hydrogen-Ion Concentration', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008970', 'descriptor_name': 'Molecular Weight', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D055550', 'descriptor_name': 'Protein Stability', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D059748', 'descriptor_name': 'Proteolysis', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D017422', 'descriptor_name': 'Sequence Analysis, DNA', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D012997', 'descriptor_name': 'Solvents', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013379', 'descriptor_name': 'Substrate Specificity', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D020860', 'descriptor_name': 'Subtilisin', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013696', 'descriptor_name': 'Temperature', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1016/j.ijbiomac.2017.11.133', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S83853393', 'display_name': 'International Journal of Biological Macromolecules', 'issn_l': '0141-8130', 'issn': ['0141-8130', '1879-0003'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/29174357', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'display_name': 'Clean water and sanitation', 'score': 0.65, 'id': 'https://metadata.un.org/sdg/6'}], 'grants': [{'funder': 'https://openalex.org/F4320325392', 'funder_display_name': 'Bilim, Sanayi ve Teknoloji Bakanliği', 'award_id': '0026.TGSD.20152'}], 'datasets': [], 'versions': [], 'referenced_works_count': 41, 'referenced_works': ['https://openalex.org/W1094360208', 'https://openalex.org/W126109032', 'https://openalex.org/W1484104843', 'https://openalex.org/W1579170119', 'https://openalex.org/W1652464928', 'https://openalex.org/W1930916251', 'https://openalex.org/W1965134559', 'https://openalex.org/W1968567870', 'https://openalex.org/W1968788542', 'https://openalex.org/W1973029229', 'https://openalex.org/W1974103341', 'https://openalex.org/W1978668215', 'https://openalex.org/W1979655538', 'https://openalex.org/W1982161409', 'https://openalex.org/W1996936181', 'https://openalex.org/W1997234557', 'https://openalex.org/W1998565346', 'https://openalex.org/W2000474378', 'https://openalex.org/W2000476985', 'https://openalex.org/W2009888675', 'https://openalex.org/W2010285210', 'https://openalex.org/W2012164221', 'https://openalex.org/W2032924530', 'https://openalex.org/W2040685013', 'https://openalex.org/W2043685439', 'https://openalex.org/W2051311598', 'https://openalex.org/W2055543934', 'https://openalex.org/W2058584290', 'https://openalex.org/W2061583103', 'https://openalex.org/W2064908976', 'https://openalex.org/W2074619350', 'https://openalex.org/W2078848660', 'https://openalex.org/W2085074262', 'https://openalex.org/W2086914954', 'https://openalex.org/W2100837269', 'https://openalex.org/W2102131116', 'https://openalex.org/W2128635872', 'https://openalex.org/W2410020835', 'https://openalex.org/W2469229025', 'https://openalex.org/W4237491994', 'https://openalex.org/W4293247451'], 'related_works': ['https://openalex.org/W3005624443', 'https://openalex.org/W2770482307', 'https://openalex.org/W2249418334', 'https://openalex.org/W2116024419', 'https://openalex.org/W2078848660', 'https://openalex.org/W2071717928', 'https://openalex.org/W2061568535', 'https://openalex.org/W2029441210', 'https://openalex.org/W2026727532', 'https://openalex.org/W2003038676'], 'abstract_inverted_index': None, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2770482307', 'counts_by_year': [{'year': 2024, 'cited_by_count': 4}, {'year': 2023, 'cited_by_count': 5}, {'year': 2022, 'cited_by_count': 5}, {'year': 2021, 'cited_by_count': 3}, {'year': 2020, 'cited_by_count': 3}, {'year': 2019, 'cited_by_count': 2}, {'year': 2018, 'cited_by_count': 2}], 'updated_date': '2024-12-16T09:17:44.117896', 'created_date': '2017-12-04'}