Publication Information

{'id': 'https://openalex.org/W2769532298', 'doi': 'https://doi.org/10.1136/annrheumdis-2017-212046', 'title': 'Presence of monosodium urate crystal deposition by dual-energy CT in patients with gout treated with allopurinol', 'display_name': 'Presence of monosodium urate crystal deposition by dual-energy CT in patients with gout treated with allopurinol', 'publication_year': 2017, 'publication_date': '2017-11-16', 'ids': {'openalex': 'https://openalex.org/W2769532298', 'doi': 'https://doi.org/10.1136/annrheumdis-2017-212046', 'mag': '2769532298', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/29146741', 'pmcid': 'https://www.ncbi.nlm.nih.gov/pmc/articles/5867403'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1136/annrheumdis-2017-212046', 'pdf_url': 'https://ard.bmj.com/content/annrheumdis/77/3/364.full.pdf', 'source': {'id': 'https://openalex.org/S25650217', 'display_name': 'Annals of the Rheumatic Diseases', 'issn_l': '0003-4967', 'issn': ['0003-4967', '1468-2060'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310319945', 'host_organization_name': 'BMJ', 'host_organization_lineage': ['https://openalex.org/P4310319945'], 'host_organization_lineage_names': ['BMJ'], 'type': 'journal'}, 'license': 'cc-by-nc', 'license_id': 'https://openalex.org/licenses/cc-by-nc', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'hybrid', 'oa_url': 'https://ard.bmj.com/content/annrheumdis/77/3/364.full.pdf', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5086285989', 'display_name': 'Nicola Dalbeth', 'orcid': 'https://orcid.org/0000-0003-4632-4476'}, 'institutions': [{'id': 'https://openalex.org/I154130895', 'display_name': 'University of Auckland', 'ror': 'https://ror.org/03b94tp07', 'country_code': 'NZ', 'type': 'education', 'lineage': ['https://openalex.org/I154130895']}], 'countries': ['NZ'], 'is_corresponding': True, 'raw_author_name': 'Nicola Dalbeth', 'raw_affiliation_strings': ['Department of Medicine, University of Auckland, Auckland 1023, New Zealand'], 'affiliations': [{'raw_affiliation_string': 'Department of Medicine, University of Auckland, Auckland 1023, New Zealand', 'institution_ids': ['https://openalex.org/I154130895']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5071405883', 'display_name': 'Savvas Nicolaou', 'orcid': 'https://orcid.org/0000-0002-4203-6605'}, 'institutions': [{'id': 'https://openalex.org/I2802832906', 'display_name': 'Vancouver General Hospital', 'ror': 'https://ror.org/02zg69r60', 'country_code': 'CA', 'type': 'healthcare', 'lineage': ['https://openalex.org/I141074466', 'https://openalex.org/I2799475292', 'https://openalex.org/I2802832906']}, {'id': 'https://openalex.org/I141945490', 'display_name': 'University of British Columbia', 'ror': 'https://ror.org/03rmrcq20', 'country_code': 'CA', 'type': 'education', 'lineage': ['https://openalex.org/I141945490']}], 'countries': ['CA'], 'is_corresponding': False, 'raw_author_name': 'Savvas Nicolaou', 'raw_affiliation_strings': ['Department of Radiology, Vancouver General Hospital and University of British Columbia, Vancouver, British Columbia, Canada'], 'affiliations': [{'raw_affiliation_string': 'Department of Radiology, Vancouver General Hospital and University of British Columbia, Vancouver, British Columbia, Canada', 'institution_ids': ['https://openalex.org/I2802832906', 'https://openalex.org/I141945490']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5032801878', 'display_name': 'Scott Baumgartner', 'orcid': 'https://orcid.org/0000-0002-4745-4021'}, 'institutions': [], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Scott Baumgartner', 'raw_affiliation_strings': ['Formerly Ardea Biosciences, Inc., San Diego, California, USA'], 'affiliations': [{'raw_affiliation_string': 'Formerly Ardea Biosciences, Inc., San Diego, California, USA', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5075122118', 'display_name': 'Jia Hu', 'orcid': 'https://orcid.org/0000-0003-2174-5864'}, 'institutions': [], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Jia Hu', 'raw_affiliation_strings': ['Formerly Ardea Biosciences, Inc., San Diego, California, USA'], 'affiliations': [{'raw_affiliation_string': 'Formerly Ardea Biosciences, Inc., San Diego, California, USA', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5069157708', 'display_name': 'Maple M. Fung', 'orcid': None}, 'institutions': [], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Maple Fung', 'raw_affiliation_strings': ['Formerly Ardea Biosciences, Inc., San Diego, California, USA'], 'affiliations': [{'raw_affiliation_string': 'Formerly Ardea Biosciences, Inc., San Diego, California, USA', 'institution_ids': []}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5087655468', 'display_name': 'Hyon K. Choi', 'orcid': 'https://orcid.org/0000-0002-2862-0442'}, 'institutions': [{'id': 'https://openalex.org/I4210087915', 'display_name': 'Massachusetts General Hospital', 'ror': 'https://ror.org/002pd6e78', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210087915', 'https://openalex.org/I48633490']}, {'id': 'https://openalex.org/I136199984', 'display_name': 'Harvard University', 'ror': 'https://ror.org/03vek6s52', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I136199984']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Hyon K Choi', 'raw_affiliation_strings': ['Department of Rheumatology, Harvard Medical School and Massachusetts General Hospital, Boston, Massachusetts, USA'], 'affiliations': [{'raw_affiliation_string': 'Department of Rheumatology, Harvard Medical School and Massachusetts General Hospital, Boston, Massachusetts, USA', 'institution_ids': ['https://openalex.org/I4210087915', 'https://openalex.org/I136199984']}]}], 'institution_assertions': [], 'countries_distinct_count': 3, 'institutions_distinct_count': 5, 'corresponding_author_ids': ['https://openalex.org/A5086285989'], 'corresponding_institution_ids': ['https://openalex.org/I154130895'], 'apc_list': None, 'apc_paid': None, 'fwci': 4.751, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 51, 'citation_normalized_percentile': {'value': 0.85764, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 96, 'max': 97}, 'biblio': {'volume': '77', 'issue': '3', 'first_page': '364', 'last_page': '370'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T11139', 'display_name': 'Gout, Hyperuricemia, Uric Acid', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/2727', 'display_name': 'Nephrology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T11139', 'display_name': 'Gout, Hyperuricemia, Uric Acid', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/2727', 'display_name': 'Nephrology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T12833', 'display_name': 'Bartonella species infections research', 'score': 0.904, 'subfield': {'id': 'https://openalex.org/subfields/2405', 'display_name': 'Parasitology'}, 'field': {'id': 'https://openalex.org/fields/24', 'display_name': 'Immunology and Microbiology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/allopurinol', 'display_name': 'Allopurinol', 'score': 0.8756056}, {'id': 'https://openalex.org/keywords/deposition', 'display_name': 'Deposition', 'score': 0.44358018}, {'id': 'https://openalex.org/keywords/tophus', 'display_name': 'Tophus', 'score': 0.43158394}], 'concepts': [{'id': 'https://openalex.org/C2780402116', 'wikidata': 'https://www.wikidata.org/wiki/Q133087', 'display_name': 'Gout', 'level': 2, 'score': 0.91460025}, {'id': 'https://openalex.org/C2780261098', 'wikidata': 'https://www.wikidata.org/wiki/Q412486', 'display_name': 'Allopurinol', 'level': 2, 'score': 0.8756056}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.85726655}, {'id': 'https://openalex.org/C2779881121', 'wikidata': 'https://www.wikidata.org/wiki/Q105522', 'display_name': 'Uric acid', 'level': 2, 'score': 0.49983025}, {'id': 'https://openalex.org/C64297162', 'wikidata': 'https://www.wikidata.org/wiki/Q1987070', 'display_name': 'Deposition (geology)', 'level': 3, 'score': 0.44358018}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.43180013}, {'id': 'https://openalex.org/C2777385986', 'wikidata': 'https://www.wikidata.org/wiki/Q2293277', 'display_name': 'Tophus', 'level': 4, 'score': 0.43158394}, {'id': 'https://openalex.org/C141071460', 'wikidata': 'https://www.wikidata.org/wiki/Q40821', 'display_name': 'Surgery', 'level': 1, 'score': 0.40049678}, {'id': 'https://openalex.org/C126894567', 'wikidata': 'https://www.wikidata.org/wiki/Q105650', 'display_name': 'Urology', 'level': 1, 'score': 0.34366584}, {'id': 'https://openalex.org/C2779721657', 'wikidata': 'https://www.wikidata.org/wiki/Q49970', 'display_name': 'Hyperuricemia', 'level': 3, 'score': 0.28842562}, {'id': 'https://openalex.org/C151730666', 'wikidata': 'https://www.wikidata.org/wiki/Q7205', 'display_name': 'Paleontology', 'level': 1, 'score': 0.0}, {'id': 'https://openalex.org/C2816523', 'wikidata': 'https://www.wikidata.org/wiki/Q180184', 'display_name': 'Sediment', 'level': 2, 'score': 0.0}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D000493', 'descriptor_name': 'Allopurinol', 'qualifier_ui': 'Q000627', 'qualifier_name': 'therapeutic use', 'is_major_topic': True}, {'descriptor_ui': 'D015210', 'descriptor_name': 'Arthritis, Gouty', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D006074', 'descriptor_name': 'Gout Suppressants', 'qualifier_ui': 'Q000627', 'qualifier_name': 'therapeutic use', 'is_major_topic': True}, {'descriptor_ui': 'D014057', 'descriptor_name': 'Tomography, X-Ray Computed', 'qualifier_ui': 'Q000379', 'qualifier_name': 'methods', 'is_major_topic': True}, {'descriptor_ui': 'D014527', 'descriptor_name': 'Uric Acid', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D000328', 'descriptor_name': 'Adult', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000368', 'descriptor_name': 'Aged', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000493', 'descriptor_name': 'Allopurinol', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015210', 'descriptor_name': 'Arthritis, Gouty', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015210', 'descriptor_name': 'Arthritis, Gouty', 'qualifier_ui': 'Q000000981', 'qualifier_name': 'diagnostic imaging', 'is_major_topic': False}, {'descriptor_ui': 'D015210', 'descriptor_name': 'Arthritis, Gouty', 'qualifier_ui': 'Q000188', 'qualifier_name': 'drug therapy', 'is_major_topic': False}, {'descriptor_ui': 'D005260', 'descriptor_name': 'Female', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006074', 'descriptor_name': 'Gout Suppressants', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008297', 'descriptor_name': 'Male', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008875', 'descriptor_name': 'Middle Aged', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009520', 'descriptor_name': 'New Zealand', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015995', 'descriptor_name': 'Prevalence', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011446', 'descriptor_name': 'Prospective Studies', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D012720', 'descriptor_name': 'Severity of Illness Index', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D014057', 'descriptor_name': 'Tomography, X-Ray Computed', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D014481', 'descriptor_name': 'United States', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D014527', 'descriptor_name': 'Uric Acid', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 6, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.1136/annrheumdis-2017-212046', 'pdf_url': 'https://ard.bmj.com/content/annrheumdis/77/3/364.full.pdf', 'source': {'id': 'https://openalex.org/S25650217', 'display_name': 'Annals of the Rheumatic Diseases', 'issn_l': '0003-4967', 'issn': ['0003-4967', '1468-2060'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310319945', 'host_organization_name': 'BMJ', 'host_organization_lineage': ['https://openalex.org/P4310319945'], 'host_organization_lineage_names': ['BMJ'], 'type': 'journal'}, 'license': 'cc-by-nc', 'license_id': 'https://openalex.org/licenses/cc-by-nc', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://europepmc.org/articles/pmc5867403', 'pdf_url': 'https://europepmc.org/articles/pmc5867403?pdf=render', 'source': {'id': 'https://openalex.org/S4306400806', 'display_name': 'Europe PMC (PubMed Central)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1303153112', 'host_organization_name': 'European Bioinformatics Institute', 'host_organization_lineage': ['https://openalex.org/I1303153112'], 'host_organization_lineage_names': ['European Bioinformatics Institute'], 'type': 'repository'}, 'license': 'cc-by-nc', 'license_id': 'https://openalex.org/licenses/cc-by-nc', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'http://nrs.harvard.edu/urn-3:HUL.InstRepos:35981880', 'pdf_url': 'https://dash.harvard.edu/bitstream/1/35981880/1/5867403.pdf', 'source': {'id': 'https://openalex.org/S4306401540', 'display_name': 'Digital Access to Scholarship at Harvard (DASH) (Harvard University)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I136199984', 'host_organization_name': 'Harvard University', 'host_organization_lineage': ['https://openalex.org/I136199984'], 'host_organization_lineage_names': ['Harvard University'], 'type': 'repository'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'http://ard.bmj.com/cgi/content/short/77/3/364', 'pdf_url': 'http://ard.bmj.com/content/77/3/364.full.pdf', 'source': {'id': 'https://openalex.org/S128516502', 'display_name': 'Notes and Queries', 'issn_l': '0029-3970', 'issn': ['0029-3970', '1471-6941'], 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/P4310311648', 'host_organization_name': 'Oxford University Press', 'host_organization_lineage': ['https://openalex.org/P4310311647', 'https://openalex.org/P4310311648'], 'host_organization_lineage_names': ['University of Oxford', 'Oxford University Press'], 'type': 'journal'}, 'license': 'cc-by-nc', 'license_id': 'https://openalex.org/licenses/cc-by-nc', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5867403', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/29146741', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1136/annrheumdis-2017-212046', 'pdf_url': 'https://ard.bmj.com/content/annrheumdis/77/3/364.full.pdf', 'source': {'id': 'https://openalex.org/S25650217', 'display_name': 'Annals of the Rheumatic Diseases', 'issn_l': '0003-4967', 'issn': ['0003-4967', '1468-2060'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310319945', 'host_organization_name': 'BMJ', 'host_organization_lineage': ['https://openalex.org/P4310319945'], 'host_organization_lineage_names': ['BMJ'], 'type': 'journal'}, 'license': 'cc-by-nc', 'license_id': 'https://openalex.org/licenses/cc-by-nc', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [{'score': 0.69, 'display_name': 'Affordable and clean energy', 'id': 'https://metadata.un.org/sdg/7'}], 'grants': [{'funder': 'https://openalex.org/F4320307770', 'funder_display_name': 'AstraZeneca', 'award_id': None}], 'datasets': [], 'versions': [], 'referenced_works_count': 25, 'referenced_works': ['https://openalex.org/W1534146221', 'https://openalex.org/W1965212373', 'https://openalex.org/W1972065756', 'https://openalex.org/W1995340484', 'https://openalex.org/W2000166571', 'https://openalex.org/W2002664886', 'https://openalex.org/W2008245966', 'https://openalex.org/W2009110061', 'https://openalex.org/W2017160927', 'https://openalex.org/W2020409699', 'https://openalex.org/W2030653458', 'https://openalex.org/W2044334793', 'https://openalex.org/W2052661775', 'https://openalex.org/W2058214311', 'https://openalex.org/W2070426536', 'https://openalex.org/W2078280696', 'https://openalex.org/W2106983312', 'https://openalex.org/W2114365596', 'https://openalex.org/W2122184429', 'https://openalex.org/W2124187588', 'https://openalex.org/W2125560723', 'https://openalex.org/W2166084391', 'https://openalex.org/W2168582455', 'https://openalex.org/W2335302945', 'https://openalex.org/W2761615158'], 'related_works': ['https://openalex.org/W4311821803', 'https://openalex.org/W4255417148', 'https://openalex.org/W4251906466', 'https://openalex.org/W3085858615', 'https://openalex.org/W2883284954', 'https://openalex.org/W2410573108', 'https://openalex.org/W2130470649', 'https://openalex.org/W2052661775', 'https://openalex.org/W1993899114', 'https://openalex.org/W1553052470'], 'abstract_inverted_index': {'Objective': [0], 'Dual-energy': [1], 'CT': [2], '(DECT)': [3], 'detects': [4], 'and': [5, 29, 58, 72, 92, 97, 106, 112, 163, 175, 196, 240, 250], 'quantifies': [6], 'monosodium': [7], 'urate': [8, 77], '(MSU)': [9], 'crystal': [10, 19, 35, 84, 130, 138, 152, 180, 201, 224, 255], 'deposition': [11, 20, 85, 131, 153, 181, 202], 'with': [12, 23, 26, 39, 42, 69, 75, 134, 159, 171, 185, 205, 237], 'high': [13], 'precision.': [14], 'This': [15], 'DECT': [16, 105], 'study': [17], 'assessed': [18, 103], 'in': [21, 88], 'patients': [22, 68, 118, 158, 218], 'gout': [24, 40, 113, 189], 'treated': [25, 41], 'stable-dose': [27], 'allopurinol,': [28], 'investigated': [30], 'potential': [31], 'clinical': [32, 241], 'determinants': [33], 'for': [34, 47, 123, 232], 'deposition.': [36, 256], 'Methods': [37], 'Patients': [38, 236], 'allopurinol': [43, 120, 228], '≥300': [44, 121, 230], 'mg': [45], 'daily': [46], 'at': [48], 'least': [49], '3': [50, 143, 147, 194], 'months': [51, 195], 'were': [52, 102], 'prospectively': [53], 'recruited': [54], 'from': [55, 155], 'the': [56, 89, 192], 'USA': [57], 'New': [59], 'Zealand,': [60], 'using': [61], 'monitored': [62], 'enrolment': [63], 'to': [64, 109, 167], 'include': [65], 'approximately': [66, 73], '25%': [67], 'palpable': [70, 165, 220], 'tophi': [71, 166, 221], '50%': [74], 'serum': [76], '(sUA)': [78], 'levels': [79, 111], '<6.0': [80, 161], 'mg/dL': [81, 162, 174], '(<357µmol/L).': [82], 'MSU': [83, 223, 254], 'was': [86, 182], 'measured': [87], 'hands/wrists,': [90], 'feet/ankles/Achilles': [91], 'knees': [93], 'bilaterally.': [94], 'The': [95, 149], 'presence': [96], 'total': [98, 137], 'volume': [99, 139, 178, 199, 252], 'of': [100, 140, 151, 179, 200, 209, 217, 243, 253], 'crystals': [101], 'by': [104], 'analysed': [107], 'according': [108], 'sUA': [110, 160, 172, 186, 239], 'characteristics.': [114], 'Results': [115], 'Among': [116], '152': [117], 'receiving': [119, 227], 'mg/day': [122, 231], '5.1': [124], 'years': [125], 'on': [126, 132], 'average,': [127], '69.1%': [128], 'had': [129], 'DECT,': [133], 'a': [135, 233, 247], 'median': [136], '0.16': [141], 'cm': [142, 146], '(range:': [144], '0.01–19.53': [145], ').': [148], 'prevalence': [150], 'ranged': [154], '46.9%': [156], 'among': [157, 169], 'no': [164], '90.0%': [168], 'those': [170], '≥6.0': [173, 187], 'tophi.': [176, 197], 'Total': [177, 198], 'positively': [183, 204], 'associated': [184], 'mg/dL,': [188], 'flares': [190], 'within': [191], 'past': [193], 'correlated': [203], 'Patient': [206], 'Global': [207], 'Impression': [208], 'Disease': [210], 'Activity': [211], 'scores.': [212], 'Conclusion': [213], 'A': [214], 'substantial': [215], 'proportion': [216], 'without': [219], 'have': [222, 246], 'deposition,': [225], 'despite': [226], 'doses': [229], 'considerable': [234], 'duration.': [235], 'higher': [238, 248], 'features': [242], 'severe': [244], 'disease': [245], 'frequency': [249], 'greater': [251]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2769532298', 'counts_by_year': [{'year': 2024, 'cited_by_count': 3}, {'year': 2023, 'cited_by_count': 6}, {'year': 2022, 'cited_by_count': 7}, {'year': 2021, 'cited_by_count': 8}, {'year': 2020, 'cited_by_count': 12}, {'year': 2019, 'cited_by_count': 11}, {'year': 2018, 'cited_by_count': 2}], 'updated_date': '2024-12-27T02:48:25.134165', 'created_date': '2017-12-04'}