Publication Information

{'id': 'https://openalex.org/W2766726410', 'doi': None, 'title': 'Complement C5 - eScholarship', 'display_name': 'Complement C5 - eScholarship', 'publication_year': 2012, 'publication_date': '2012-01-01', 'ids': {'openalex': 'https://openalex.org/W2766726410', 'mag': '2766726410'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://escholarship.org/content/qt76k5d1mt/qt76k5d1mt.pdf', 'pdf_url': None, 'source': None, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': [], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5067365133', 'display_name': 'Anjana Chandrasekhar', 'orcid': 'https://orcid.org/0009-0001-5113-5576'}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Anjana Chandrasekhar', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5059749945', 'display_name': 'Ashok Reddy Dinasarapu', 'orcid': 'https://orcid.org/0000-0002-1423-1518'}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Ashok Reddy Dinasarapu', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5000201491', 'display_name': 'David E. 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'display_name': 'Complement system in diseases', 'score': 0.9993, 'subfield': {'id': 'https://openalex.org/subfields/2403', 'display_name': 'Immunology'}, 'field': {'id': 'https://openalex.org/fields/24', 'display_name': 'Immunology and Microbiology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10993', 'display_name': 'Complement system in diseases', 'score': 0.9993, 'subfield': {'id': 'https://openalex.org/subfields/2403', 'display_name': 'Immunology'}, 'field': {'id': 'https://openalex.org/fields/24', 'display_name': 'Immunology and Microbiology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10091', 'display_name': 'Malaria Research and Control', 'score': 0.9636, 'subfield': {'id': 'https://openalex.org/subfields/2739', 'display_name': 'Public Health, Environmental and Occupational Health'}, 'field': {'id': 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'https://www.wikidata.org/wiki/Q4736500', 'display_name': 'Alternative complement pathway', 'level': 4, 'score': 0.40881416}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.39586288}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.39375216}, {'id': 'https://openalex.org/C159654299', 'wikidata': 'https://www.wikidata.org/wiki/Q79460', 'display_name': 'Antibody', 'level': 2, 'score': 0.37052274}, {'id': 'https://openalex.org/C170493617', 'wikidata': 'https://www.wikidata.org/wiki/Q208467', 'display_name': 'Receptor', 'level': 2, 'score': 0.29856926}, {'id': 'https://openalex.org/C203014093', 'wikidata': 'https://www.wikidata.org/wiki/Q101929', 'display_name': 'Immunology', 'level': 1, 'score': 0.26757896}, {'id': 'https://openalex.org/C127716648', 'wikidata': 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'https://openalex.org/W2912022140', 'https://openalex.org/W2911285109', 'https://openalex.org/W2911269908', 'https://openalex.org/W2461467707', 'https://openalex.org/W2171533933', 'https://openalex.org/W208642478', 'https://openalex.org/W2063026975', 'https://openalex.org/W2061899289', 'https://openalex.org/W2037082249', 'https://openalex.org/W2009351133', 'https://openalex.org/W1980514201', 'https://openalex.org/W1975460168', 'https://openalex.org/W1971302922', 'https://openalex.org/W186082473', 'https://openalex.org/W1515152089', 'https://openalex.org/W115227093', 'https://openalex.org/W108386553'], 'abstract_inverted_index': {'Complement': [0], 'C5': [1, 40, 60, 186, 210, 220], 'is': [2, 18, 41, 57, 94], 'a': [3, 11, 22, 29, 34, 95, 127, 146, 225], '189': [4], 'kDa': [5, 31, 36], 'protein': [6], 'synthesized': [7], 'in': [8, 43, 99, 126, 149, 165, 196, 214], 'liver': [9], 'as': [10], 'single-chain': [12], 'precursor': [13, 16], 'molecule.': [14], 'The': [15, 198], 'molecule': [17], 'then': [19], 'cleaved': [20, 58], 'to': [21, 70, 114, 130, 227], 'disulfide': [23], 'linked': [24], 'two-chain': [25], 'glycoprotein': [26], 'consisting': [27], 'of': [28, 101, 105, 110, 160], '115': [30], '(C5α)': [32], 'and': [33, 53, 76, 84, 103, 124, 153, 162], '75': [35], 'N-terminal': [37], '(C5β)': [38], 'chain.': [39], 'present': [42], 'all': [44], 'the': [45, 66, 132, 150, 155, 158, 167], 'three': [46], 'known': [47], 'complement': [48, 67, 134], 'activation': [49, 68], 'pathways:': [50], 'classical,': [51], 'alternative': [52], 'lectin.': [54], 'C5α': [55], 'chain': [56, 78, 83, 86], 'by': [59, 191], 'convertases,': [61], 'which': [62, 180], 'are': [63, 188, 221], 'formed': [64], 'during': [65], 'process,': [69], 'form': [71, 91, 131], 'C5a': [72, 93, 111, 161], '(74': [73], 'a.a': [74, 80], 'long)': [75, 89], "C5α'": [77, 82], '(925': [79], 'long).': [81], 'C5β': [85], '(655': [87], 'a.a.': [88], 'together': [90], 'C5b.': [92], 'major': [96], 'anaphylotoxin': [97], 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'cells.': [184], 'Therefore,': [185], 'tightly': [189], 'regulated': [190], 'interaction': [192], 'with': [193, 224], 'other': [194], 'proteins': [195, 200], 'host.': [197], 'regulatory': [199], 'either': [202], 'generated': [205], 'pathogenic': [207], 'factors.': [208], 'Unregulated': [209], 'function': [211], 'result': [213], 'disease': [215], 'phenotypes.': [216], 'Therapeutic': [217], 'antibodies': [218], 'against': [219], 'being': [222], 'developed': [223], 'view': [226], 'treat': [228], 'these': [229], 'conditions.': [230]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2766726410', 'counts_by_year': [], 'updated_date': '2024-12-09T22:24:22.343384', 'created_date': '2017-11-10'}