Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2764483221', 'doi': 'https://doi.org/10.1038/169628a0', 'title': 'Origin of the Resistance of Leukæmic Cells to Folic Acid Antagonists', 'display_name': 'Origin of the Resistance of Leukæmic Cells to Folic Acid Antagonists', 'publication_year': 1952, 'publication_date': '1952-04-01', 'ids': {'openalex': 'https://openalex.org/W2764483221', 'doi': 'https://doi.org/10.1038/169628a0', 'mag': '2764483221', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/14929259'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1038/169628a0', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S137773608', 'display_name': 'Nature', 'issn_l': '0028-0836', 'issn': ['0028-0836', '1476-4687'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310319908', 'host_organization_name': 'Nature Portfolio', 'host_organization_lineage': ['https://openalex.org/P4310319908', 'https://openalex.org/P4310319965'], 'host_organization_lineage_names': ['Nature Portfolio', 'Springer Nature'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5034888318', 'display_name': 'L. W. Law', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I35344726', 'display_name': 'United States Public Health Service', 'ror': 'https://ror.org/05xf94514', 'country_code': 'US', 'type': 'government', 'lineage': ['https://openalex.org/I1299022934', 'https://openalex.org/I35344726']}, {'id': 'https://openalex.org/I1299303238', 'display_name': 'National Institutes of Health', 'ror': 'https://ror.org/01cwqze88', 'country_code': 'US', 'type': 'government', 'lineage': ['https://openalex.org/I1299022934', 'https://openalex.org/I1299303238']}, {'id': 'https://openalex.org/I4210140884', 'display_name': 'National Cancer Institute', 'ror': 'https://ror.org/040gcmg81', 'country_code': 'US', 'type': 'government', 'lineage': ['https://openalex.org/I1299022934', 'https://openalex.org/I1299303238', 'https://openalex.org/I4210140884']}], 'countries': ['US'], 'is_corresponding': True, 'raw_author_name': 'L. W. LAW', 'raw_affiliation_strings': ['National Cancer Institute, National Institutes of Health, U.S. Public Health Service, Bethesda, Maryland'], 'affiliations': [{'raw_affiliation_string': 'National Cancer Institute, National Institutes of Health, U.S. Public Health Service, Bethesda, Maryland', 'institution_ids': ['https://openalex.org/I35344726', 'https://openalex.org/I1299303238', 'https://openalex.org/I4210140884']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 3, 'corresponding_author_ids': ['https://openalex.org/A5034888318'], 'corresponding_institution_ids': ['https://openalex.org/I35344726', 'https://openalex.org/I1299303238', 'https://openalex.org/I4210140884'], 'apc_list': {'value': 9750, 'currency': 'EUR', 'value_usd': 11690, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 4.665, 'has_fulltext': False, 'cited_by_count': 117, 'citation_normalized_percentile': {'value': 0.98293, 'is_in_top_1_percent': False, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 98, 'max': 99}, 'biblio': {'volume': '169', 'issue': '4302', 'first_page': '628', 'last_page': '629'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T11559', 'display_name': 'Role of Retinoic Acid in Biological Processes', 'score': 0.9531, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T11559', 'display_name': 'Role of Retinoic Acid in Biological Processes', 'score': 0.9531, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10309', 'display_name': 'Acute Myeloid Leukemia', 'score': 0.9309, 'subfield': {'id': 'https://openalex.org/subfields/2720', 'display_name': 'Hematology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/folic-acid-antagonists', 'display_name': 'Folic Acid Antagonists', 'score': 0.80628455}, {'id': 'https://openalex.org/keywords/differentiation-therapy', 'display_name': 'Differentiation Therapy', 'score': 0.458394}], 'concepts': [{'id': 'https://openalex.org/C2992130864', 'wikidata': 'https://www.wikidata.org/wiki/Q127060', 'display_name': 'Folic acid', 'level': 2, 'score': 0.83021766}, {'id': 'https://openalex.org/C2909344506', 'wikidata': 'https://www.wikidata.org/wiki/Q50573407', 'display_name': 'Folic Acid Antagonists', 'level': 3, 'score': 0.80628455}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.47409114}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.37870768}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.35166454}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.25703865}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.11463395}], 'mesh': [{'descriptor_ui': 'D001669', 'descriptor_name': 'Biochemical Phenomena', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D005493', 'descriptor_name': 'Folic Acid Antagonists', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D007942', 'descriptor_name': 'Leukemia, Experimental', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1038/169628a0', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S137773608', 'display_name': 'Nature', 'issn_l': '0028-0836', 'issn': ['0028-0836', '1476-4687'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310319908', 'host_organization_name': 'Nature Portfolio', 'host_organization_lineage': ['https://openalex.org/P4310319908', 'https://openalex.org/P4310319965'], 'host_organization_lineage_names': ['Nature Portfolio', 'Springer Nature'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/14929259', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'id': 'https://metadata.un.org/sdg/2', 'display_name': 'Zero hunger', 'score': 0.59}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 9, 'referenced_works': ['https://openalex.org/W1850815376', 'https://openalex.org/W1980718269', 'https://openalex.org/W2009283420', 'https://openalex.org/W2053815207', 'https://openalex.org/W2091354017', 'https://openalex.org/W2170343590', 'https://openalex.org/W2330188305', 'https://openalex.org/W2412837864', 'https://openalex.org/W4239077426'], 'related_works': ['https://openalex.org/W4205211075', 'https://openalex.org/W3145203298', 'https://openalex.org/W3023065389', 'https://openalex.org/W2779102286', 'https://openalex.org/W2777855446', 'https://openalex.org/W2764483221', 'https://openalex.org/W2467388356', 'https://openalex.org/W2397470459', 'https://openalex.org/W2067712716', 'https://openalex.org/W1962995064'], 'abstract_inverted_index': None, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2764483221', 'counts_by_year': [{'year': 2023, 'cited_by_count': 2}, {'year': 2022, 'cited_by_count': 1}, {'year': 2021, 'cited_by_count': 1}, {'year': 2020, 'cited_by_count': 1}, {'year': 2018, 'cited_by_count': 3}, {'year': 2017, 'cited_by_count': 5}, {'year': 2016, 'cited_by_count': 3}, {'year': 2014, 'cited_by_count': 2}, {'year': 2012, 'cited_by_count': 4}], 'updated_date': '2024-09-14T17:20:20.805125', 'created_date': '2017-10-27'}