Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2761956704', 'doi': 'https://doi.org/10.18632/oncotarget.21744', 'title': 'Fluorescence contrast-enhanced proliferative lesion imaging by enema administration of indocyanine green in a rat model of colon carcinogenesis', 'display_name': 'Fluorescence contrast-enhanced proliferative lesion imaging by enema administration of indocyanine green in a rat model of colon carcinogenesis', 'publication_year': 2017, 'publication_date': '2017-10-09', 'ids': {'openalex': 'https://openalex.org/W2761956704', 'doi': 'https://doi.org/10.18632/oncotarget.21744', 'mag': '2761956704', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/29163827', 'pmcid': 'https://www.ncbi.nlm.nih.gov/pmc/articles/5685748'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.18632/oncotarget.21744', 'pdf_url': 'https://www.oncotarget.com/article/21744/pdf/', 'source': {'id': 'https://openalex.org/S126644158', 'display_name': 'Oncotarget', 'issn_l': '1949-2553', 'issn': ['1949-2553'], 'is_oa': True, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310316297', 'host_organization_name': 'Impact Journals LLC', 'host_organization_lineage': ['https://openalex.org/P4310316297'], 'host_organization_lineage_names': ['Impact Journals LLC'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'gold', 'oa_url': 'https://www.oncotarget.com/article/21744/pdf/', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5058709234', 'display_name': 'Nobuhiko Onda', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I36940870', 'display_name': 'Olympus (Japan)', 'ror': 'https://ror.org/01v0pgv63', 'country_code': 'JP', 'type': 'company', 'lineage': ['https://openalex.org/I36940870']}, {'id': 'https://openalex.org/I92614990', 'display_name': 'Tokyo University of Agriculture and Technology', 'ror': 'https://ror.org/00qg0kr10', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I92614990']}, {'id': 'https://openalex.org/I4210111488', 'display_name': 'Life Science Institute', 'ror': 'https://ror.org/01yeyd808', 'country_code': 'JP', 'type': 'facility', 'lineage': ['https://openalex.org/I4210111488']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Nobuhiko Onda', 'raw_affiliation_strings': ['Evaluation Technology Department 1, R&D Group, Olympus Corporation, Hachioji, Tokyo 192-8512, Japan', 'Laboratory of Veterinary Pathology, Division of Animal Life Science, Institute of Agriculture, Tokyo University of Agriculture and Technology, Fuchu, Tokyo 183-8509, Japan'], 'affiliations': [{'raw_affiliation_string': 'Evaluation Technology Department 1, R&D Group, Olympus Corporation, Hachioji, Tokyo 192-8512, Japan', 'institution_ids': ['https://openalex.org/I36940870']}, {'raw_affiliation_string': 'Laboratory of Veterinary Pathology, Division of Animal Life Science, Institute of Agriculture, Tokyo University of Agriculture and Technology, Fuchu, Tokyo 183-8509, Japan', 'institution_ids': ['https://openalex.org/I92614990', 'https://openalex.org/I4210111488']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5040542769', 'display_name': 'Reiko Mizutani-Morita', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210111488', 'display_name': 'Life Science Institute', 'ror': 'https://ror.org/01yeyd808', 'country_code': 'JP', 'type': 'facility', 'lineage': ['https://openalex.org/I4210111488']}, {'id': 'https://openalex.org/I92614990', 'display_name': 'Tokyo University of Agriculture and Technology', 'ror': 'https://ror.org/00qg0kr10', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I92614990']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Reiko Mizutani-Morita', 'raw_affiliation_strings': ['Laboratory of Veterinary Pathology, Division of Animal Life Science, Institute of Agriculture, Tokyo University of Agriculture and Technology, Fuchu, Tokyo 183-8509, Japan'], 'affiliations': [{'raw_affiliation_string': 'Laboratory of Veterinary Pathology, Division of Animal Life Science, Institute of Agriculture, Tokyo University of Agriculture and Technology, Fuchu, Tokyo 183-8509, Japan', 'institution_ids': ['https://openalex.org/I4210111488', 'https://openalex.org/I92614990']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5069562625', 'display_name': 'Susumu Yamashita', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I36940870', 'display_name': 'Olympus (Japan)', 'ror': 'https://ror.org/01v0pgv63', 'country_code': 'JP', 'type': 'company', 'lineage': ['https://openalex.org/I36940870']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Susumu Yamashita', 'raw_affiliation_strings': ['Evaluation Technology Department 1, R&D Group, Olympus Corporation, Hachioji, Tokyo 192-8512, Japan'], 'affiliations': [{'raw_affiliation_string': 'Evaluation Technology Department 1, R&D Group, Olympus Corporation, Hachioji, Tokyo 192-8512, Japan', 'institution_ids': ['https://openalex.org/I36940870']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5081045160', 'display_name': 'Rei Nagahara', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I92614990', 'display_name': 'Tokyo University of Agriculture and Technology', 'ror': 'https://ror.org/00qg0kr10', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I92614990']}, {'id': 'https://openalex.org/I4210111488', 'display_name': 'Life Science Institute', 'ror': 'https://ror.org/01yeyd808', 'country_code': 'JP', 'type': 'facility', 'lineage': ['https://openalex.org/I4210111488']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Rei Nagahara', 'raw_affiliation_strings': ['Laboratory of Veterinary Pathology, Division of Animal Life Science, Institute of Agriculture, Tokyo University of Agriculture and Technology, Fuchu, Tokyo 183-8509, Japan'], 'affiliations': [{'raw_affiliation_string': 'Laboratory of Veterinary Pathology, Division of Animal Life Science, Institute of Agriculture, Tokyo University of Agriculture and Technology, Fuchu, Tokyo 183-8509, Japan', 'institution_ids': ['https://openalex.org/I92614990', 'https://openalex.org/I4210111488']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5101472129', 'display_name': 'Shinya Matsumoto', 'orcid': 'https://orcid.org/0000-0001-5166-9036'}, 'institutions': [{'id': 'https://openalex.org/I36940870', 'display_name': 'Olympus (Japan)', 'ror': 'https://ror.org/01v0pgv63', 'country_code': 'JP', 'type': 'company', 'lineage': ['https://openalex.org/I36940870']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Shinya Matsumoto', 'raw_affiliation_strings': ['Evaluation Technology Department 1, R&D Group, Olympus Corporation, Hachioji, Tokyo 192-8512, Japan'], 'affiliations': [{'raw_affiliation_string': 'Evaluation Technology Department 1, R&D Group, Olympus Corporation, Hachioji, Tokyo 192-8512, Japan', 'institution_ids': ['https://openalex.org/I36940870']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5055943723', 'display_name': 'Toshinori Yoshida', 'orcid': 'https://orcid.org/0000-0003-2476-7794'}, 'institutions': [{'id': 'https://openalex.org/I92614990', 'display_name': 'Tokyo University of Agriculture and Technology', 'ror': 'https://ror.org/00qg0kr10', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I92614990']}, {'id': 'https://openalex.org/I4210111488', 'display_name': 'Life Science Institute', 'ror': 'https://ror.org/01yeyd808', 'country_code': 'JP', 'type': 'facility', 'lineage': ['https://openalex.org/I4210111488']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Toshinori Yoshida', 'raw_affiliation_strings': ['Laboratory of Veterinary Pathology, Division of Animal Life Science, Institute of Agriculture, Tokyo University of Agriculture and Technology, Fuchu, Tokyo 183-8509, Japan'], 'affiliations': [{'raw_affiliation_string': 'Laboratory of Veterinary Pathology, Division of Animal Life Science, Institute of Agriculture, Tokyo University of Agriculture and Technology, Fuchu, Tokyo 183-8509, Japan', 'institution_ids': ['https://openalex.org/I92614990', 'https://openalex.org/I4210111488']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5062202170', 'display_name': 'Makoto Shibutani', 'orcid': 'https://orcid.org/0000-0003-3417-9697'}, 'institutions': [{'id': 'https://openalex.org/I92614990', 'display_name': 'Tokyo University of Agriculture and Technology', 'ror': 'https://ror.org/00qg0kr10', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I92614990']}, {'id': 'https://openalex.org/I4210111488', 'display_name': 'Life Science Institute', 'ror': 'https://ror.org/01yeyd808', 'country_code': 'JP', 'type': 'facility', 'lineage': ['https://openalex.org/I4210111488']}], 'countries': ['JP'], 'is_corresponding': True, 'raw_author_name': 'Makoto Shibutani', 'raw_affiliation_strings': ['Institute of Global Innovation Research, Tokyo University of Agriculture and Technology, Fuchu, Tokyo 183-8509, Japan', 'Laboratory of Veterinary Pathology, Division of Animal Life Science, Institute of Agriculture, Tokyo University of Agriculture and Technology, Fuchu, Tokyo 183-8509, Japan'], 'affiliations': [{'raw_affiliation_string': 'Laboratory of Veterinary Pathology, Division of Animal Life Science, Institute of Agriculture, Tokyo University of Agriculture and Technology, Fuchu, Tokyo 183-8509, Japan', 'institution_ids': ['https://openalex.org/I92614990', 'https://openalex.org/I4210111488']}, {'raw_affiliation_string': 'Institute of Global Innovation Research, Tokyo University of Agriculture and Technology, Fuchu, Tokyo 183-8509, Japan', 'institution_ids': ['https://openalex.org/I92614990']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 3, 'corresponding_author_ids': ['https://openalex.org/A5062202170'], 'corresponding_institution_ids': ['https://openalex.org/I92614990', 'https://openalex.org/I4210111488'], 'apc_list': None, 'apc_paid': None, 'fwci': 0.35, 'has_fulltext': True, 'fulltext_origin': 'pdf', 'cited_by_count': 16, 'citation_normalized_percentile': {'value': 0.719501, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 89, 'max': 90}, 'biblio': {'volume': '8', 'issue': '52', 'first_page': '90278', 'last_page': '90290'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10782', 'display_name': 'Nanoplatforms for cancer theranostics', 'score': 0.9953, 'subfield': {'id': 'https://openalex.org/subfields/2204', 'display_name': 'Biomedical Engineering'}, 'field': {'id': 'https://openalex.org/fields/22', 'display_name': 'Engineering'}, 'domain': {'id': 'https://openalex.org/domains/3', 'display_name': 'Physical Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10782', 'display_name': 'Nanoplatforms for cancer theranostics', 'score': 0.9953, 'subfield': {'id': 'https://openalex.org/subfields/2204', 'display_name': 'Biomedical Engineering'}, 'field': {'id': 'https://openalex.org/fields/22', 'display_name': 'Engineering'}, 'domain': {'id': 'https://openalex.org/domains/3', 'display_name': 'Physical Sciences'}}, {'id': 'https://openalex.org/T10335', 'display_name': 'Colorectal Cancer Surgical Treatments', 'score': 0.9946, 'subfield': {'id': 'https://openalex.org/subfields/2730', 'display_name': 'Oncology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T11872', 'display_name': 'Barrier Structure and Function Studies', 'score': 0.9942, 'subfield': {'id': 'https://openalex.org/subfields/2808', 'display_name': 'Neurology'}, 'field': {'id': 'https://openalex.org/fields/28', 'display_name': 'Neuroscience'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/indocyanine-green', 'display_name': 'Indocyanine Green', 'score': 0.80471826}, {'id': 'https://openalex.org/keywords/ex-vivo', 'display_name': 'Ex vivo', 'score': 0.60642904}], 'concepts': [{'id': 'https://openalex.org/C2781065829', 'wikidata': 'https://www.wikidata.org/wiki/Q905662', 'display_name': 'Indocyanine green', 'level': 2, 'score': 0.80471826}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.61648655}, {'id': 'https://openalex.org/C26291073', 'wikidata': 'https://www.wikidata.org/wiki/Q310484', 'display_name': 'Ex vivo', 'level': 3, 'score': 0.60642904}, {'id': 'https://openalex.org/C207001950', 'wikidata': 'https://www.wikidata.org/wiki/Q141124', 'display_name': 'In vivo', 'level': 2, 'score': 0.53328735}, {'id': 'https://openalex.org/C142724271', 'wikidata': 'https://www.wikidata.org/wiki/Q7208', 'display_name': 'Pathology', 'level': 1, 'score': 0.5050183}, {'id': 'https://openalex.org/C502942594', 'wikidata': 'https://www.wikidata.org/wiki/Q3421914', 'display_name': 'Cancer research', 'level': 1, 'score': 0.34407014}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.17088407}, {'id': 'https://openalex.org/C150903083', 'wikidata': 'https://www.wikidata.org/wiki/Q7108', 'display_name': 'Biotechnology', 'level': 1, 'score': 0.0}], 'mesh': [], 'locations_count': 4, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.18632/oncotarget.21744', 'pdf_url': 'https://www.oncotarget.com/article/21744/pdf/', 'source': {'id': 'https://openalex.org/S126644158', 'display_name': 'Oncotarget', 'issn_l': '1949-2553', 'issn': ['1949-2553'], 'is_oa': True, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310316297', 'host_organization_name': 'Impact Journals LLC', 'host_organization_lineage': ['https://openalex.org/P4310316297'], 'host_organization_lineage_names': ['Impact Journals LLC'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://europepmc.org/articles/pmc5685748', 'pdf_url': 'https://europepmc.org/articles/pmc5685748?pdf=render', 'source': {'id': 'https://openalex.org/S4306400806', 'display_name': 'Europe PMC (PubMed Central)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1303153112', 'host_organization_name': 'European Bioinformatics Institute', 'host_organization_lineage': ['https://openalex.org/I1303153112'], 'host_organization_lineage_names': ['European Bioinformatics Institute'], 'type': 'repository'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5685748', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/29163827', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.18632/oncotarget.21744', 'pdf_url': 'https://www.oncotarget.com/article/21744/pdf/', 'source': {'id': 'https://openalex.org/S126644158', 'display_name': 'Oncotarget', 'issn_l': '1949-2553', 'issn': ['1949-2553'], 'is_oa': True, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310316297', 'host_organization_name': 'Impact Journals LLC', 'host_organization_lineage': ['https://openalex.org/P4310316297'], 'host_organization_lineage_names': ['Impact Journals LLC'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [{'id': 'https://metadata.un.org/sdg/9', 'score': 0.48, 'display_name': 'Industry, innovation and infrastructure'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 53, 'referenced_works': ['https://openalex.org/W1562674989', 'https://openalex.org/W1570518064', 'https://openalex.org/W1595008039', 'https://openalex.org/W1734393961', 'https://openalex.org/W1836629525', 'https://openalex.org/W1908319679', 'https://openalex.org/W1965694893', 'https://openalex.org/W1966046384', 'https://openalex.org/W1968889670', 'https://openalex.org/W1970192608', 'https://openalex.org/W1971901938', 'https://openalex.org/W1974100712', 'https://openalex.org/W1977871291', 'https://openalex.org/W1991136374', 'https://openalex.org/W1997518603', 'https://openalex.org/W2017054309', 'https://openalex.org/W2023215982', 'https://openalex.org/W2024256483', 'https://openalex.org/W2026762108', 'https://openalex.org/W2034245991', 'https://openalex.org/W2047033241', 'https://openalex.org/W2048691571', 'https://openalex.org/W2048824414', 'https://openalex.org/W2053690364', 'https://openalex.org/W2067721149', 'https://openalex.org/W2072335482', 'https://openalex.org/W2078636414', 'https://openalex.org/W2079208474', 'https://openalex.org/W2088659772', 'https://openalex.org/W2097476366', 'https://openalex.org/W2122382231', 'https://openalex.org/W2126293994', 'https://openalex.org/W2129840658', 'https://openalex.org/W2132668016', 'https://openalex.org/W2135311331', 'https://openalex.org/W2140876736', 'https://openalex.org/W2141250106', 'https://openalex.org/W2143929290', 'https://openalex.org/W2152149158', 'https://openalex.org/W2153178471', 'https://openalex.org/W2165513594', 'https://openalex.org/W2310748356', 'https://openalex.org/W2317165081', 'https://openalex.org/W2329539599', 'https://openalex.org/W2338272197', 'https://openalex.org/W2341975764', 'https://openalex.org/W2418198376', 'https://openalex.org/W2460171264', 'https://openalex.org/W2469283207', 'https://openalex.org/W2475207250', 'https://openalex.org/W2508881103', 'https://openalex.org/W2565903169', 'https://openalex.org/W2917837889'], 'related_works': ['https://openalex.org/W4390989393', 'https://openalex.org/W4389023408', 'https://openalex.org/W2979791217', 'https://openalex.org/W2554934382', 'https://openalex.org/W2435059856', 'https://openalex.org/W2185621195', 'https://openalex.org/W2140910281', 'https://openalex.org/W2037182962', 'https://openalex.org/W2021806548', 'https://openalex.org/W1975498499'], 'abstract_inverted_index': {'//': [0], 'Nobuhiko': [1], 'Onda': [2], '1,': [3, 33], '2': [4, 8, 16, 24, 42], ',': [5, 9, 13, 17, 21], 'Reiko': [6], 'Mizutani-Morita': [7], 'Susumu': [10], 'Yamashita': [11], '1': [12, 20, 29], 'Rei': [14], 'Nagahara': [15], 'Shinya': [18], 'Matsumoto': [19], 'Toshinori': [22], 'Yoshida': [23], 'and': [25, 59, 75, 122, 210, 257, 352], 'Makoto': [26, 83], 'Shibutani': [27], '2,3': [28], 'Evaluation': [30], 'Technology': [31], 'Department': [32], 'R&D': [34], 'Group,': [35], 'Olympus': [36], 'Corporation,': [37], 'Hachioji,': [38], 'Tokyo': [39, 55, 62, 71, 78], '192-8512,': [40], 'Japan': [41, 64, 80], 'Laboratory': [43], 'of': [44, 48, 53, 57, 67, 73, 148, 161, 173, 215, 226, 275, 289, 292, 305, 313, 317, 325, 341, 356], 'Veterinary': [45], 'Pathology,': [46], 'Division': [47], 'Animal': [49], 'Life': [50], 'Science,': [51], 'Institute': [52, 66], 'Agriculture,': [54], 'University': [56, 72], 'Agriculture': [58, 74], 'Technology,': [60, 76], 'Fuchu,': [61, 77], '183-8509,': [63, 79], '3': [65], 'Global': [68], 'Innovation': [69], 'Research,': [70], 'Correspondence': [81], 'to:': [82], 'Shibutani,': [84], 'email:': [85], '[email protected]': [86], 'Keywords:': [87], 'colon': [88, 134, 163, 178, 201, 246, 319], 'tumor,': [89], 'endoscopy,': [90, 206], 'fluorescence': [91, 159, 299], 'imaging,': [92], 'indocyanine': [93, 114], 'green,': [94], 'tight': [95, 150, 293, 342], 'junction': [96], 'Received:': [97], 'April': [98], '19,': [99], '2017': [100, 104, 108], 'Accepted:': [101], 'August': [102], '08,': [103], 'Published:': [105], 'October': [106], '09,': [107], 'ABSTRACT': [109], 'The': [110, 152, 170, 213, 223, 273, 322], 'fluorescent': [111], 'contrast': [112], 'agent': [113], 'green': [115], '(ICG)': [116], 'is': [117], 'approved': [118], 'by': [119, 141, 217, 349], 'the': [120, 162, 218, 227, 230, 237, 276, 283, 287, 290, 303, 311, 318, 328, 339, 353], 'Food': [121], 'Drug': [123], 'Administration': [124], 'for': [125], 'clinical': [126], 'applications.': [127], 'We': [128], 'previously': [129], 'reported': [130], 'that': [131, 298], 'cultured': [132, 176, 219], 'human': [133], 'tumor': [135, 179], 'cells': [136, 180, 220, 351], 'preferentially': [137], 'take': [138], 'up': [139], 'ICG': [140, 156, 174, 216, 240, 326], 'endocytic': [142], 'activity': [143], 'in': [144, 158, 175, 188, 197, 204, 229, 245, 259, 270, 282, 327, 332, 345], 'association': [145], 'with': [146, 199], 'disruption': [147, 288, 340], 'their': [149], 'junctions.': [151, 294], 'present': [153], 'study': [154, 334], 'explored': [155], 'availability': [157], 'imaging': [160, 301], 'to': [164, 255, 338], 'identify': [165], 'proliferative': [166, 247, 268, 284, 315, 350], 'lesions': [167, 187, 248, 269, 316], 'during': [168, 320], 'colonoscopy.': [169, 321], 'cellular': [171, 354], 'uptake': [172, 214, 238, 355], 'rat': [177, 329], 'was': [181, 221, 280], 'examined': [182], 'using': [183, 203], 'live-cell': [184], 'imaging.': [185], 'Colon': [186], 'rats': [189, 198], 'administered': [190, 241], 'an': [191, 306], 'ICG-containing': [192, 307], 'enema': [193, 243, 308], 'were': [194], 'further': [195], 'assessed': [196], 'azoxymethane-induced': [200], 'carcinogenesis,': [202], 'vivo': [205, 208, 271], 'ex': [207], 'microscopy,': [209], 'immunofluorescence': [211], 'microscopy.': [212], 'temperature-dependent.': [222], 'intracellular': [224], 'retention': [225], 'dye': [228], 'membrane': [231], 'trafficking': [232], 'system': [233], 'suggested': [234], 'endocytosis': [235, 348], 'as': [236], 'mechanism.': [239], 'via': [242], 'accumulated': [244], 'ranging': [249], 'from': [250], 'tiny': [251], 'aberrant': [252], 'crypt': [253], 'foci': [254], 'adenomas': [256], 'localized': [258], 'proliferating': [260], 'cells.': [261], 'Fluorescence': [262], 'endoscopy': [263], 'detected': [264], 'these': [265], 'ICG-positive': [266], 'colonic': [267], '.': [272], 'immunoreactivity': [274], 'tight-junction': [277], 'molecule': [278], 'occludin': [279], 'altered': [281], 'lesions,': [285], 'suggesting': [286], 'integrity': [291], 'These': [295], 'results': [296], 'suggest': [297], 'contrast-enhanced': [300], 'following': [302], 'administration': [304], 'can': [309, 335], 'enhance': [310], 'detection': [312], 'mucosal': [314], 'tissue': [323], 'preference': [324], 'model': [330], 'evaluated': [331], 'this': [333], 'be': [336], 'attributed': [337], 'junctions,': [343], 'which': [344], 'turn': [346], 'promotes': [347], 'ICG.': [357]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2761956704', 'counts_by_year': [{'year': 2024, 'cited_by_count': 2}, {'year': 2023, 'cited_by_count': 4}, {'year': 2022, 'cited_by_count': 3}, {'year': 2021, 'cited_by_count': 4}, {'year': 2020, 'cited_by_count': 2}, {'year': 2018, 'cited_by_count': 1}], 'updated_date': '2024-12-08T07:30:09.894550', 'created_date': '2017-10-20'}