Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2760534580', 'doi': 'https://doi.org/10.1093/nar/gkx844', 'title': 'Proteomic identification of histone post-translational modifications and proteins enriched at a DNA double-strand break', 'display_name': 'Proteomic identification of histone post-translational modifications and proteins enriched at a DNA double-strand break', 'publication_year': 2017, 'publication_date': '2017-09-26', 'ids': {'openalex': 'https://openalex.org/W2760534580', 'doi': 'https://doi.org/10.1093/nar/gkx844', 'mag': '2760534580', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/29036368', 'pmcid': 'https://www.ncbi.nlm.nih.gov/pmc/articles/5737490'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1093/nar/gkx844', 'pdf_url': 'https://academic.oup.com/nar/article-pdf/45/19/10923/22934709/gkx844.pdf', 'source': {'id': 'https://openalex.org/S134668137', 'display_name': 'Nucleic Acids Research', 'issn_l': '0305-1048', 'issn': ['0305-1048', '1362-4954', '1362-4962'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310311648', 'host_organization_name': 'Oxford University Press', 'host_organization_lineage': ['https://openalex.org/P4310311647', 'https://openalex.org/P4310311648'], 'host_organization_lineage_names': ['University of Oxford', 'Oxford University Press'], 'type': 'journal'}, 'license': 'cc-by-nc', 'license_id': 'https://openalex.org/licenses/cc-by-nc', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'gold', 'oa_url': 'https://academic.oup.com/nar/article-pdf/45/19/10923/22934709/gkx844.pdf', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5067159963', 'display_name': 'Pingping Wang', 'orcid': 'https://orcid.org/0000-0001-6203-5725'}, 'institutions': [{'id': 'https://openalex.org/I919571938', 'display_name': 'The University of Texas Health Science Center at Houston', 'ror': 'https://ror.org/03gds6c39', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I919571938']}, {'id': 'https://openalex.org/I205783295', 'display_name': 'Cornell University', 'ror': 'https://ror.org/05bnh6r87', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I205783295']}, {'id': 'https://openalex.org/I1343551460', 'display_name': 'The University of Texas MD Anderson Cancer Center', 'ror': 'https://ror.org/04twxam07', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1343551460']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Pingping Wang', 'raw_affiliation_strings': ['Genes and Development Graduate Program of the University of Texas MD Anderson Cancer Center, UT Health Graduate School of Biomedical Sciences, Houston, TX 77030, USA', 'Weill Cornell Medicine, Department of Pathology and Laboratory Medicine, New York, NY 10065, USA'], 'affiliations': [{'raw_affiliation_string': 'Genes and Development Graduate Program of the University of Texas MD Anderson Cancer Center, UT Health Graduate School of Biomedical Sciences, Houston, TX 77030, USA', 'institution_ids': ['https://openalex.org/I919571938', 'https://openalex.org/I1343551460', 'https://openalex.org/I919571938']}, {'raw_affiliation_string': 'Weill Cornell Medicine, Department of Pathology and Laboratory Medicine, New York, NY 10065, USA', 'institution_ids': ['https://openalex.org/I205783295']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5059818425', 'display_name': 'Stephanie D. Byrum', 'orcid': 'https://orcid.org/0000-0002-1783-3610'}, 'institutions': [{'id': 'https://openalex.org/I79620101', 'display_name': 'University of Arkansas for Medical Sciences', 'ror': 'https://ror.org/00xcryt71', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I79620101']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Stephanie Byrum', 'raw_affiliation_strings': ['University of Arkansas for Medical Sciences, Department of Biochemistry and Molecular Biology, Little Rock, AR 72205, USA'], 'affiliations': [{'raw_affiliation_string': 'University of Arkansas for Medical Sciences, Department of Biochemistry and Molecular Biology, Little Rock, AR 72205, USA', 'institution_ids': ['https://openalex.org/I79620101']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5044147790', 'display_name': 'Faith C. Fowler', 'orcid': 'https://orcid.org/0000-0002-7180-8141'}, 'institutions': [{'id': 'https://openalex.org/I205783295', 'display_name': 'Cornell University', 'ror': 'https://ror.org/05bnh6r87', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I205783295']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Faith C. Fowler', 'raw_affiliation_strings': ['Weill Cornell Medicine, Department of Pathology and Laboratory Medicine, New York, NY 10065, USA'], 'affiliations': [{'raw_affiliation_string': 'Weill Cornell Medicine, Department of Pathology and Laboratory Medicine, New York, NY 10065, USA', 'institution_ids': ['https://openalex.org/I205783295']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5015485203', 'display_name': 'Sangita Pal', 'orcid': 'https://orcid.org/0000-0002-4892-841X'}, 'institutions': [{'id': 'https://openalex.org/I919571938', 'display_name': 'The University of Texas Health Science Center at Houston', 'ror': 'https://ror.org/03gds6c39', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I919571938']}, {'id': 'https://openalex.org/I205783295', 'display_name': 'Cornell University', 'ror': 'https://ror.org/05bnh6r87', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I205783295']}, {'id': 'https://openalex.org/I1343551460', 'display_name': 'The University of Texas MD Anderson Cancer Center', 'ror': 'https://ror.org/04twxam07', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1343551460']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Sangita Pal', 'raw_affiliation_strings': ['Genes and Development Graduate Program of the University of Texas MD Anderson Cancer Center, UT Health Graduate School of Biomedical Sciences, Houston, TX 77030, USA', 'Weill Cornell Medicine, Department of Pathology and Laboratory Medicine, New York, NY 10065, USA'], 'affiliations': [{'raw_affiliation_string': 'Genes and Development Graduate Program of the University of Texas MD Anderson Cancer Center, UT Health Graduate School of Biomedical Sciences, Houston, TX 77030, USA', 'institution_ids': ['https://openalex.org/I919571938', 'https://openalex.org/I1343551460', 'https://openalex.org/I919571938']}, {'raw_affiliation_string': 'Weill Cornell Medicine, Department of Pathology and Laboratory Medicine, New York, NY 10065, USA', 'institution_ids': ['https://openalex.org/I205783295']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5032217222', 'display_name': 'Alan J. Tackett', 'orcid': 'https://orcid.org/0000-0002-3672-4460'}, 'institutions': [{'id': 'https://openalex.org/I79620101', 'display_name': 'University of Arkansas for Medical Sciences', 'ror': 'https://ror.org/00xcryt71', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I79620101']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Alan J. Tackett', 'raw_affiliation_strings': ['University of Arkansas for Medical Sciences, Department of Biochemistry and Molecular Biology, Little Rock, AR 72205, USA'], 'affiliations': [{'raw_affiliation_string': 'University of Arkansas for Medical Sciences, Department of Biochemistry and Molecular Biology, Little Rock, AR 72205, USA', 'institution_ids': ['https://openalex.org/I79620101']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5042369850', 'display_name': 'Jessica K. Tyler', 'orcid': 'https://orcid.org/0000-0001-9765-1659'}, 'institutions': [{'id': 'https://openalex.org/I205783295', 'display_name': 'Cornell University', 'ror': 'https://ror.org/05bnh6r87', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I205783295']}], 'countries': ['US'], 'is_corresponding': True, 'raw_author_name': 'Jessica K. Tyler', 'raw_affiliation_strings': ['Weill Cornell Medicine, Department of Pathology and Laboratory Medicine, New York, NY 10065, USA'], 'affiliations': [{'raw_affiliation_string': 'Weill Cornell Medicine, Department of Pathology and Laboratory Medicine, New York, NY 10065, USA', 'institution_ids': ['https://openalex.org/I205783295']}]}], 'countries_distinct_count': 1, 'institutions_distinct_count': 4, 'corresponding_author_ids': ['https://openalex.org/A5042369850'], 'corresponding_institution_ids': ['https://openalex.org/I205783295'], 'apc_list': {'value': 3630, 'currency': 'USD', 'value_usd': 3630, 'provenance': 'doaj'}, 'apc_paid': {'value': 3630, 'currency': 'USD', 'value_usd': 3630, 'provenance': 'doaj'}, 'fwci': 0.75, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 11, 'citation_normalized_percentile': {'value': 0.564863, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 86, 'max': 87}, 'biblio': {'volume': '45', 'issue': '19', 'first_page': '10923', 'last_page': '10940'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10123', 'display_name': 'Molecular Mechanisms of DNA Damage Response', 'score': 0.9993, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10123', 'display_name': 'Molecular Mechanisms of DNA Damage Response', 'score': 0.9993, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10222', 'display_name': 'Regulation of Chromatin Structure and Function', 'score': 0.9987, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10604', 'display_name': 'Regulation of RNA Processing and Function', 'score': 0.9986, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/histone-modifications', 'display_name': 'Histone Modifications', 'score': 0.526671}], 'concepts': [{'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.8406347}, {'id': 'https://openalex.org/C83640560', 'wikidata': 'https://www.wikidata.org/wiki/Q180951', 'display_name': 'Chromatin', 'level': 3, 'score': 0.62408906}, {'id': 'https://openalex.org/C64927066', 'wikidata': 'https://www.wikidata.org/wiki/Q36293', 'display_name': 'Histone', 'level': 3, 'score': 0.48902616}, {'id': 'https://openalex.org/C143425029', 'wikidata': 'https://www.wikidata.org/wiki/Q5205747', 'display_name': 'DNA damage', 'level': 3, 'score': 0.4833869}, {'id': 'https://openalex.org/C153911025', 'wikidata': 'https://www.wikidata.org/wiki/Q7202', 'display_name': 'Molecular biology', 'level': 1, 'score': 0.47437698}, {'id': 'https://openalex.org/C134935766', 'wikidata': 'https://www.wikidata.org/wiki/Q210538', 'display_name': 'DNA repair', 'level': 3, 'score': 0.45620298}, {'id': 'https://openalex.org/C56428682', 'wikidata': 'https://www.wikidata.org/wiki/Q24785535', 'display_name': 'Histone H2A', 'level': 4, 'score': 0.41897827}, {'id': 'https://openalex.org/C552990157', 'wikidata': 'https://www.wikidata.org/wiki/Q7430', 'display_name': 'DNA', 'level': 2, 'score': 0.37406874}, {'id': 'https://openalex.org/C95444343', 'wikidata': 'https://www.wikidata.org/wiki/Q7141', 'display_name': 'Cell biology', 'level': 1, 'score': 0.36348826}, {'id': 'https://openalex.org/C54355233', 'wikidata': 'https://www.wikidata.org/wiki/Q7162', 'display_name': 'Genetics', 'level': 1, 'score': 0.33594376}], 'mesh': [{'descriptor_ui': 'D053903', 'descriptor_name': 'DNA Breaks, Double-Stranded', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D006657', 'descriptor_name': 'Histones', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D011499', 'descriptor_name': 'Protein Processing, Post-Translational', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D020543', 'descriptor_name': 'Proteome', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D029701', 'descriptor_name': 'Saccharomyces cerevisiae Proteins', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D002868', 'descriptor_name': 'Chromosomal Proteins, Non-Histone', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D002868', 'descriptor_name': 'Chromosomal Proteins, Non-Histone', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D002868', 'descriptor_name': 'Chromosomal Proteins, Non-Histone', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004260', 'descriptor_name': 'DNA Repair', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006657', 'descriptor_name': 'Histones', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D006657', 'descriptor_name': 'Histones', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008239', 'descriptor_name': 'Lysine', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D008239', 'descriptor_name': 'Lysine', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D008239', 'descriptor_name': 'Lysine', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013058', 'descriptor_name': 'Mass Spectrometry', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008745', 'descriptor_name': 'Methylation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009687', 'descriptor_name': 'Nuclear Proteins', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D009687', 'descriptor_name': 'Nuclear Proteins', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D009687', 'descriptor_name': 'Nuclear Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D054648', 'descriptor_name': 'Protein Phosphatase 2', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D054648', 'descriptor_name': 'Protein Phosphatase 2', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D054648', 'descriptor_name': 'Protein Phosphatase 2', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D020543', 'descriptor_name': 'Proteome', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D020543', 'descriptor_name': 'Proteome', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D040901', 'descriptor_name': 'Proteomics', 'qualifier_ui': 'Q000379', 'qualifier_name': 'methods', 'is_major_topic': False}, {'descriptor_ui': 'D040901', 'descriptor_name': 'Proteomics', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D016601', 'descriptor_name': 'RNA-Binding Proteins', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D016601', 'descriptor_name': 'RNA-Binding Proteins', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D016601', 'descriptor_name': 'RNA-Binding Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D012441', 'descriptor_name': 'Saccharomyces cerevisiae', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D012441', 'descriptor_name': 'Saccharomyces cerevisiae', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D012441', 'descriptor_name': 'Saccharomyces cerevisiae', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D029701', 'descriptor_name': 'Saccharomyces cerevisiae Proteins', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D029701', 'descriptor_name': 'Saccharomyces cerevisiae Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D044767', 'descriptor_name': 'Ubiquitin-Protein Ligases', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D044767', 'descriptor_name': 'Ubiquitin-Protein Ligases', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D044767', 'descriptor_name': 'Ubiquitin-Protein Ligases', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 4, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.1093/nar/gkx844', 'pdf_url': 'https://academic.oup.com/nar/article-pdf/45/19/10923/22934709/gkx844.pdf', 'source': {'id': 'https://openalex.org/S134668137', 'display_name': 'Nucleic Acids Research', 'issn_l': '0305-1048', 'issn': ['0305-1048', '1362-4954', '1362-4962'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310311648', 'host_organization_name': 'Oxford University Press', 'host_organization_lineage': ['https://openalex.org/P4310311647', 'https://openalex.org/P4310311648'], 'host_organization_lineage_names': ['University of Oxford', 'Oxford University Press'], 'type': 'journal'}, 'license': 'cc-by-nc', 'license_id': 'https://openalex.org/licenses/cc-by-nc', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://europepmc.org/articles/pmc5737490', 'pdf_url': 'https://europepmc.org/articles/pmc5737490?pdf=render', 'source': {'id': 'https://openalex.org/S4306400806', 'display_name': 'Europe PMC (PubMed Central)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1303153112', 'host_organization_name': 'European Bioinformatics Institute', 'host_organization_lineage': ['https://openalex.org/I1303153112'], 'host_organization_lineage_names': ['European Bioinformatics Institute'], 'type': 'repository'}, 'license': 'cc-by-nc', 'license_id': 'https://openalex.org/licenses/cc-by-nc', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5737490', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/29036368', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1093/nar/gkx844', 'pdf_url': 'https://academic.oup.com/nar/article-pdf/45/19/10923/22934709/gkx844.pdf', 'source': {'id': 'https://openalex.org/S134668137', 'display_name': 'Nucleic Acids Research', 'issn_l': '0305-1048', 'issn': ['0305-1048', '1362-4954', '1362-4962'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310311648', 'host_organization_name': 'Oxford University Press', 'host_organization_lineage': ['https://openalex.org/P4310311647', 'https://openalex.org/P4310311648'], 'host_organization_lineage_names': ['University of Oxford', 'Oxford University Press'], 'type': 'journal'}, 'license': 'cc-by-nc', 'license_id': 'https://openalex.org/licenses/cc-by-nc', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 68, 'referenced_works': ['https://openalex.org/W1488992604', 'https://openalex.org/W1525080912', 'https://openalex.org/W1756179169', 'https://openalex.org/W1843907743', 'https://openalex.org/W1923529605', 'https://openalex.org/W1966072209', 'https://openalex.org/W1977022180', 'https://openalex.org/W1977188840', 'https://openalex.org/W1980725176', 'https://openalex.org/W1985188792', 'https://openalex.org/W1989943265', 'https://openalex.org/W2002140176', 'https://openalex.org/W2016991182', 'https://openalex.org/W2025972514', 'https://openalex.org/W2029971236', 'https://openalex.org/W2033411843', 'https://openalex.org/W2035910115', 'https://openalex.org/W2036298138', 'https://openalex.org/W2036546456', 'https://openalex.org/W2038860354', 'https://openalex.org/W2041380706', 'https://openalex.org/W2042688172', 'https://openalex.org/W2043682043', 'https://openalex.org/W2051289873', 'https://openalex.org/W2052389165', 'https://openalex.org/W2058794536', 'https://openalex.org/W2060297254', 'https://openalex.org/W2066526435', 'https://openalex.org/W2071955851', 'https://openalex.org/W2077436902', 'https://openalex.org/W2077828161', 'https://openalex.org/W2080522986', 'https://openalex.org/W2081702399', 'https://openalex.org/W2083431317', 'https://openalex.org/W2086046991', 'https://openalex.org/W2086932102', 'https://openalex.org/W2087826539', 'https://openalex.org/W2088189164', 'https://openalex.org/W2092627694', 'https://openalex.org/W2098659547', 'https://openalex.org/W2100203117', 'https://openalex.org/W2100867350', 'https://openalex.org/W2106985615', 'https://openalex.org/W2107643519', 'https://openalex.org/W2107712228', 'https://openalex.org/W2107836354', 'https://openalex.org/W2114989280', 'https://openalex.org/W2118438547', 'https://openalex.org/W2122488874', 'https://openalex.org/W2127200148', 'https://openalex.org/W2140210955', 'https://openalex.org/W2142437744', 'https://openalex.org/W2144171940', 'https://openalex.org/W2144792857', 'https://openalex.org/W2145200068', 'https://openalex.org/W2145929363', 'https://openalex.org/W2155277330', 'https://openalex.org/W2161906145', 'https://openalex.org/W2163082684', 'https://openalex.org/W2163765191', 'https://openalex.org/W2167261518', 'https://openalex.org/W2172147368', 'https://openalex.org/W2322249983', 'https://openalex.org/W2409065418', 'https://openalex.org/W2568885441', 'https://openalex.org/W4254432601', 'https://openalex.org/W4256308671', 'https://openalex.org/W4320995249'], 'related_works': ['https://openalex.org/W98379584', 'https://openalex.org/W2760815521', 'https://openalex.org/W2747101336', 'https://openalex.org/W2413824894', 'https://openalex.org/W2055890925', 'https://openalex.org/W2055566470', 'https://openalex.org/W2033918102', 'https://openalex.org/W2004480716', 'https://openalex.org/W1991644354', 'https://openalex.org/W1972094156'], 'abstract_inverted_index': {'Here,': [0], 'we': [1, 108], 'use': [2], 'ChAP-MS': [3], '(chromatin': [4], 'affinity': [5, 12], 'purification': [6, 13], 'with': [7], 'mass': [8], 'spectrometry),': [9], 'for': [10, 95, 103, 125, 134, 159], 'the': [11, 68, 71, 78, 84, 138, 153, 165], 'of': [14, 44, 47, 90, 137, 156], 'a': [15, 22, 38, 65, 113], 'sequence-specific': [16], 'single-copy': [17], 'endogenous': [18], 'chromosomal': [19], 'locus': [20], 'containing': [21], 'DNA': [23, 139, 166], 'double-strand': [24], 'break': [25], '(DSB).': [26], 'We': [27], 'found': [28], 'multiple': [29], 'new': [30], 'histone': [31, 48], 'post-translational': [32], 'modifications': [33], 'enriched': [34, 63], 'on': [35, 50], 'chromatin': [36], 'bearing': [37], 'DSB': [39, 66, 116, 126, 143], 'from': [40], 'budding': [41], 'yeast.': [42, 119], 'One': [43], 'these,': [45], 'methylation': [46], 'H3': [49], 'lysine': [51], '125,': [52], 'has': [53, 150], 'not': [54], 'previously': [55], 'been': [56], 'reported.': [57], 'Among': [58], 'over': [59], '100': [60], 'novel': [61, 157], 'proteins': [62, 92, 163], 'at': [64], 'were': [67, 101, 123], 'phosphatase': [69], 'Sit4,': [70], 'RNA': [72], 'pol': [73], 'II': [74], 'degradation': [75], 'factor': [76], 'Def1,': [77], 'mRNA': [79], 'export': [80], 'protein': [81], 'Yra1': [82, 120], 'and': [83, 99, 121, 161], 'HECT': [85], 'E3': [86], 'ligase': [87], 'Tom1.': [88], 'Each': [89], 'these': [91, 160], 'was': [93, 132], 'required': [94, 102, 124, 133], 'resistance': [96, 104], 'to': [97, 105, 111, 152], 'radiomimetics,': [98], 'many': [100], 'heat,': [106], 'which': [107], 'show': [109], 'here': [110], 'cause': [112], 'defect': [114], 'in': [115, 118, 164], 'repair': [117, 127], 'Def1': [122], 'per': [128], 'se,': [129], 'while': [130], 'Sit4': [131], 'rapid': [135], 'inactivation': [136], 'damage': [140, 167], 'checkpoint': [141], 'after': [142], 'repair.': [144], 'Thus,': [145], 'our': [146], 'unbiased': [147], 'proteomics': [148], 'approach': [149], 'led': [151], 'unexpected': [154], 'discovery': [155], 'roles': [158], 'other': [162], 'response.': [168]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2760534580', 'counts_by_year': [{'year': 2023, 'cited_by_count': 1}, {'year': 2021, 'cited_by_count': 3}, {'year': 2019, 'cited_by_count': 3}, {'year': 2018, 'cited_by_count': 4}], 'updated_date': '2024-08-29T15:16:53.664538', 'created_date': '2017-10-06'}