Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2757901224', 'doi': 'https://doi.org/10.51415/10321/2577', 'title': 'Investigation of acute systemic inflammatory response and myocardial injury after cardiac surgery in patients infected with human immunodeficiency virus', 'display_name': 'Investigation of acute systemic inflammatory response and myocardial injury after cardiac surgery in patients infected with human immunodeficiency virus', 'publication_year': 2016, 'publication_date': '2016-01-01', 'ids': {'openalex': 'https://openalex.org/W2757901224', 'doi': 'https://doi.org/10.51415/10321/2577', 'mag': '2757901224'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.51415/10321/2577', 'pdf_url': 'https://openscholar.dut.ac.za/bitstream/10321/2577/1/GOJO_MKE_2016.pdf', 'source': None, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'dissertation', 'type_crossref': 'dissertation', 'indexed_in': ['crossref'], 'open_access': {'is_oa': True, 'oa_status': 'bronze', 'oa_url': 'https://openscholar.dut.ac.za/bitstream/10321/2577/1/GOJO_MKE_2016.pdf', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5010916805', 'display_name': 'Mawande Khayalethu Edson Gojo', 'orcid': None}, 'institutions': [], 'countries': [], 'is_corresponding': True, 'raw_author_name': 'Mawande Khayalethu Edson Gojo', 'raw_affiliation_strings': [], 'affiliations': []}], 'institution_assertions': [], 'countries_distinct_count': 0, 'institutions_distinct_count': 0, 'corresponding_author_ids': ['https://openalex.org/A5010916805'], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': None, 'has_fulltext': True, 'fulltext_origin': 'pdf', 'cited_by_count': 0, 'citation_normalized_percentile': {'value': 0.0, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 0, 'max': 66}, 'biblio': {'volume': None, 'issue': None, 'first_page': None, 'last_page': None}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T12598', 'display_name': 'Cardiac Structural Anomalies and Repair', 'score': 0.9952, 'subfield': {'id': 'https://openalex.org/subfields/2746', 'display_name': 'Surgery'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T12598', 'display_name': 'Cardiac Structural Anomalies and Repair', 'score': 0.9952, 'subfield': {'id': 'https://openalex.org/subfields/2746', 'display_name': 'Surgery'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T11055', 'display_name': 'Cardiac and Coronary Surgery Techniques', 'score': 0.9943, 'subfield': {'id': 'https://openalex.org/subfields/2746', 'display_name': 'Surgery'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10172', 'display_name': 'Cardiac Valve Diseases and Treatments', 'score': 0.9936, 'subfield': {'id': 'https://openalex.org/subfields/2705', 'display_name': 'Cardiology and Cardiovascular Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/erythrocyte-sedimentation-rate', 'display_name': 'Erythrocyte sedimentation rate', 'score': 0.46348527}], 'concepts': [{'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.8859215}, {'id': 'https://openalex.org/C31174226', 'wikidata': 'https://www.wikidata.org/wiki/Q64855140', 'display_name': 'Perioperative', 'level': 2, 'score': 0.6820712}, {'id': 'https://openalex.org/C2778881276', 'wikidata': 'https://www.wikidata.org/wiki/Q552304', 'display_name': 'Cardiopulmonary bypass', 'level': 2, 'score': 0.6772064}, {'id': 'https://openalex.org/C115725540', 'wikidata': 'https://www.wikidata.org/wiki/Q7846263', 'display_name': 'Troponin I', 'level': 3, 'score': 0.6244944}, {'id': 'https://openalex.org/C2778384902', 'wikidata': 'https://www.wikidata.org/wiki/Q183134', 'display_name': 'Sepsis', 'level': 2, 'score': 0.5563339}, {'id': 'https://openalex.org/C2778789114', 'wikidata': 'https://www.wikidata.org/wiki/Q235007', 'display_name': 'Cardiac surgery', 'level': 2, 'score': 0.5267952}, {'id': 'https://openalex.org/C188816634', 'wikidata': 'https://www.wikidata.org/wiki/Q2113324', 'display_name': 'Prospective cohort study', 'level': 2, 'score': 0.49673826}, {'id': 'https://openalex.org/C2778143017', 'wikidata': 'https://www.wikidata.org/wiki/Q111208', 'display_name': 'Erythrocyte sedimentation rate', 'level': 2, 'score': 0.46348527}, {'id': 'https://openalex.org/C2781197716', 'wikidata': 'https://www.wikidata.org/wiki/Q864574', 'display_name': 'Biomarker', 'level': 2, 'score': 0.4390067}, {'id': 'https://openalex.org/C42219234', 'wikidata': 'https://www.wikidata.org/wiki/Q131130', 'display_name': 'Anesthesia', 'level': 1, 'score': 0.43207815}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.41527694}, {'id': 'https://openalex.org/C90924648', 'wikidata': 'https://www.wikidata.org/wiki/Q120569', 'display_name': 'Gastroenterology', 'level': 1, 'score': 0.40272424}, {'id': 'https://openalex.org/C500558357', 'wikidata': 'https://www.wikidata.org/wiki/Q12152', 'display_name': 'Myocardial infarction', 'level': 2, 'score': 0.24146512}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.0}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.0}], 'mesh': [], 'locations_count': 1, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.51415/10321/2577', 'pdf_url': 'https://openscholar.dut.ac.za/bitstream/10321/2577/1/GOJO_MKE_2016.pdf', 'source': None, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.51415/10321/2577', 'pdf_url': 'https://openscholar.dut.ac.za/bitstream/10321/2577/1/GOJO_MKE_2016.pdf', 'source': None, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [{'score': 0.81, 'display_name': 'Good health and well-being', 'id': 'https://metadata.un.org/sdg/3'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 114, 'referenced_works': ['https://openalex.org/W135094439', 'https://openalex.org/W1499246780', 'https://openalex.org/W1584525935', 'https://openalex.org/W1588780716', 'https://openalex.org/W161965515', 'https://openalex.org/W1885081232', 'https://openalex.org/W1966466467', 'https://openalex.org/W1970526206', 'https://openalex.org/W1973018733', 'https://openalex.org/W1973406883', 'https://openalex.org/W1976991589', 'https://openalex.org/W1977665434', 'https://openalex.org/W1978305466', 'https://openalex.org/W1978473068', 'https://openalex.org/W1980296214', 'https://openalex.org/W1982280354', 'https://openalex.org/W1983665682', 'https://openalex.org/W1985011397', 'https://openalex.org/W1985146664', 'https://openalex.org/W1987852115', 'https://openalex.org/W1992814825', 'https://openalex.org/W2000774409', 'https://openalex.org/W2003105217', 'https://openalex.org/W2005283722', 'https://openalex.org/W2005464155', 'https://openalex.org/W2006204222', 'https://openalex.org/W2007320066', 'https://openalex.org/W2015671484', 'https://openalex.org/W2016168268', 'https://openalex.org/W2017927066', 'https://openalex.org/W2022668610', 'https://openalex.org/W2024448456', 'https://openalex.org/W2031102666', 'https://openalex.org/W2031350441', 'https://openalex.org/W2032914709', 'https://openalex.org/W2033403165', 'https://openalex.org/W2033702812', 'https://openalex.org/W2036632357', 'https://openalex.org/W2043931994', 'https://openalex.org/W2046254468', 'https://openalex.org/W2047266401', 'https://openalex.org/W2048238199', 'https://openalex.org/W2048470272', 'https://openalex.org/W2057520423', 'https://openalex.org/W2061933717', 'https://openalex.org/W2062602745', 'https://openalex.org/W2067823130', 'https://openalex.org/W2072151191', 'https://openalex.org/W2072636099', 'https://openalex.org/W2074324267', 'https://openalex.org/W2078785742', 'https://openalex.org/W2081463929', 'https://openalex.org/W2081920788', 'https://openalex.org/W2082297510', 'https://openalex.org/W2089226005', 'https://openalex.org/W2092173577', 'https://openalex.org/W2092498025', 'https://openalex.org/W2092853152', 'https://openalex.org/W2093762250', 'https://openalex.org/W2096109794', 'https://openalex.org/W2097155000', 'https://openalex.org/W2098262405', 'https://openalex.org/W2100471492', 'https://openalex.org/W2102452596', 'https://openalex.org/W2104749679', 'https://openalex.org/W2111153977', 'https://openalex.org/W2114075528', 'https://openalex.org/W2114253485', 'https://openalex.org/W2114280375', 'https://openalex.org/W2117035897', 'https://openalex.org/W2120497592', 'https://openalex.org/W2123254057', 'https://openalex.org/W2123599889', 'https://openalex.org/W2127077465', 'https://openalex.org/W2127634309', 'https://openalex.org/W2128876187', 'https://openalex.org/W2129324312', 'https://openalex.org/W2130194184', 'https://openalex.org/W2137021890', 'https://openalex.org/W2143077267', 'https://openalex.org/W2146793040', 'https://openalex.org/W2149617617', 'https://openalex.org/W2150031858', 'https://openalex.org/W2153741943', 'https://openalex.org/W2156212005', 'https://openalex.org/W2157040546', 'https://openalex.org/W2158211112', 'https://openalex.org/W2163912921', 'https://openalex.org/W2164074570', 'https://openalex.org/W2167081101', 'https://openalex.org/W2236550050', 'https://openalex.org/W2298123820', 'https://openalex.org/W2320264340', 'https://openalex.org/W2321021560', 'https://openalex.org/W2330162926', 'https://openalex.org/W2414227321', 'https://openalex.org/W2428715553', 'https://openalex.org/W2479671428', 'https://openalex.org/W2484238733', 'https://openalex.org/W2507554592', 'https://openalex.org/W2514129211', 'https://openalex.org/W2569680470', 'https://openalex.org/W2741861641', 'https://openalex.org/W3025120472', 'https://openalex.org/W3174512386', 'https://openalex.org/W4231502455', 'https://openalex.org/W4242045327', 'https://openalex.org/W4245286435', 'https://openalex.org/W4247018960', 'https://openalex.org/W4247365960', 'https://openalex.org/W4249965191', 'https://openalex.org/W4386040726', 'https://openalex.org/W61294449', 'https://openalex.org/W779307780'], 'related_works': ['https://openalex.org/W4323894198', 'https://openalex.org/W4210540426', 'https://openalex.org/W4210486955', 'https://openalex.org/W3032294988', 'https://openalex.org/W2409262985', 'https://openalex.org/W2393078530', 'https://openalex.org/W2337520786', 'https://openalex.org/W2271356446', 'https://openalex.org/W2134267284', 'https://openalex.org/W2069234075'], 'abstract_inverted_index': {'Introduction:': [0], 'The': [1, 86, 139, 172, 266], 'immediate': [2], 'post-cardiopulmonary': [3], 'bypass': [4], '(CPB)': [5], 'immune': [6], 'responses': [7], 'and': [8, 41, 60, 90, 103, 121, 126, 130, 135, 149, 153, 169, 175, 204, 232, 248, 273, 285, 296, 377], 'organ': [9], 'injuries': [10], 'in': [11, 123, 216, 245, 254, 260, 271, 280, 305, 311, 323, 328, 342], 'immune-': [12], 'compromised': [13], 'patients': [14, 34, 54, 59], 'remain': [15], 'poorly': [16], 'documented.': [17], 'We': [18, 235, 347, 369], 'conducted': [19], 'a': [20, 71, 77, 109, 237, 320], 'prospective': [21], 'clinical': [22], 'study': [23], 'to': [24, 47, 132, 336, 355, 363, 385], 'determine': [25], 'whether': [26], 'or': [27], 'not': [28, 259, 277, 310, 383], 'human': [29], 'immunodeficiency': [30], 'virus': [31], '(HIV)': [32], 'seropositive': [33, 58, 148, 256, 307, 331], 'generate': [35], 'higher': [36], 'acute': [37, 100], 'systemic': [38], 'inflammatory': [39, 101], 'response': [40], 'suffer': [42], 'greater': [43], 'myocardial': [44, 114], 'injury,': [45], 'compared': [46, 129], 'HIV': [48, 57, 147, 330, 350, 366], 'seronegative': [49], 'patients.': [50, 368], 'Methodology:': [51], 'Sixty-one': [52], 'consecutive': [53], 'i.e.': [55], 'Thirty': [56], 'Thirty-one': [61], 'seronegative,': [62], 'undergoing': [63], 'elective': [64], 'cardiac': [65, 104, 356], 'valve(s)': [66], 'replacement': [67], 'were': [68, 95, 118, 128, 177], 'enrolled,': [69], 'over': [70], 'period': [72], 'of': [73, 99, 340, 365], 'nine': [74], 'months': [75], 'from': [76], 'single': [78], 'center': [79], 'hospital,': [80], 'after': [81], 'informed': [82], 'consent': [83], 'was': [84, 143, 276, 303], 'acquired.': [85], 'C-reactive': [87], 'protein': [88], '(CRP)': [89], 'Erythrocyte': [91], 'sedimentation': [92], 'rate': [93], '(ESR)': [94], 'used': [96], 'as': [97, 108], 'biomarkers': [98, 214, 376], 'response,': [102], 'troponin': [105], 'I': [106], '(cTnI)': [107], 'biomarker': [110], 'for': [111], 'measuring': [112], 'postoperative': [113, 294, 353], 'injury.': [115], 'Single': [116], 'tests': [117], 'measured': [119], 'preoperatively': [120], 'postoperatively,': [122], 'both': [124, 158, 217, 281], 'groups,': [125, 183, 218, 308], 'these': [127, 381], 'correlated': [131], 'perioperative': [133, 378], 'events': [134, 174, 189], 'CPB': [136, 173, 184, 188, 195, 199, 205, 360], 'parameters.': [137], 'Results:': [138], 'mean': [140, 226, 229, 243], 'age': [141], 'group': [142, 151, 263, 282, 314], 'similar': [144, 362], 'between': [145, 180, 223, 241, 268, 279, 293, 374, 390], 'the': [146, 181, 224, 242, 255, 261, 269, 297, 306, 312, 329, 338, 375, 387, 391], 'negative': [150, 239, 313], '(37.8': [152], '37.1': [154], 'years,': [155], 'respectively).': [156, 288], 'Preoperatively': [157], 'groups': [159], 'had': [160], 'relatively': [161], 'equal': [162], 'CRP': [163, 227, 246, 272], 'levels': [164, 167, 247], '(p=0.388),': [165], 'ESR': [166, 230], '(p=0.817)': [168], 'cTnI': [170, 233, 295], '(p=0.489).': [171], 'durations': [176], 'significantly': [178], 'different': [179], 'two': [182, 392], 'duration': [185, 193, 300], '(p=0.021).': [186], 'Other': [187], 'include,': [190], 'clamp': [191], 'aortic': [192], '(p=0.026),': [194], 'blood': [196], 'transfusion': [197], '(p=0.013),': [198], 'total': [200], 'urine': [201], 'output': [202], '(p=0.035)': [203], 'peak': [206], 'lactate': [207], '(p=0.040).': [208], 'Postoperatively': [209], 'we': [210, 318], 'observed': [211, 236, 319], 'significant': [212, 221, 238, 278, 290, 321], 'increased': [213], 'level': [215], 'with': [219], 'no': [220], 'difference': [222, 270], 'groups:': [225], '(p=0.115),': [228], '(p=0.214)': [231], '(p=0.363).': [234], 'correlation': [240, 267, 292], 'change': [244, 341], 'mechanical': [249], 'ventilation': [250], '(r=-': [251], '0.548,': [252], 'p=0.002)': [253], 'group,': [257], 'but': [258, 309], 'uninfected': [262], '(r=0.025,': [264], 'p=0.893).': [265], 'ICU': [274], 'stay': [275], '(r=-0.231,': [283], 'p=0.229': [284], 'r=0.25,': [286], 'p=0.975,': [287], 'A': [289], 'positive': [291, 351], 'inotropic': [298], 'support': [299], '(r=0.384,': [301], 'p=0.040)': [302], 'seen': [304], '(r=0.092,': [315], 'p=0.622).': [316], 'Furthermore': [317], 'drop': [322], 'CD4': [324, 343], 'cells': [325, 344], 'postoperatively': [326], '(p=<0.001)': [327], 'group.': [332], 'Antiretroviral': [333], 'treatment': [334], 'appeared': [335], 'influence': [337], 'degree': [339], 'postoperatively.': [345], 'Conclusion:': [346], 'conclude': [348], 'that': [349], 'patients’': [352], 'reactions': [354], 'surgery': [357], 'supported': [358], 'by': [359], 'are': [361], 'those': [364], 'seronegetive': [367], 'further': [370], 'report': [371], 'non-paralleling': [372], 'correlations': [373], 'events;': [379], 'however': [380], 'do': [382], 'seem': [384], 'affect': [386], 'overall': [388], 'outcomes': [389], 'groups.': [393]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2757901224', 'counts_by_year': [], 'updated_date': '2024-12-10T19:33:27.652241', 'created_date': '2017-10-06'}