Publication Information

{'id': 'https://openalex.org/W2753290949', 'doi': 'https://doi.org/10.1172/jci94582', 'title': 'No evidence of HIV replication in children on antiretroviral therapy', 'display_name': 'No evidence of HIV replication in children on antiretroviral therapy', 'publication_year': 2017, 'publication_date': '2017-09-10', 'ids': {'openalex': 'https://openalex.org/W2753290949', 'doi': 'https://doi.org/10.1172/jci94582', 'mag': '2753290949', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/28891813', 'pmcid': 'https://www.ncbi.nlm.nih.gov/pmc/articles/5617669'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1172/jci94582', 'pdf_url': 'http://www.jci.org/articles/view/94582/files/pdf', 'source': {'id': 'https://openalex.org/S114430552', 'display_name': 'Journal of Clinical Investigation', 'issn_l': '0021-9738', 'issn': ['0021-9738', '1558-8238'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320279', 'host_organization_name': 'American Society for Clinical Investigation', 'host_organization_lineage': ['https://openalex.org/P4310320279'], 'host_organization_lineage_names': ['American Society for Clinical Investigation'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'bronze', 'oa_url': 'http://www.jci.org/articles/view/94582/files/pdf', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5027678141', 'display_name': 'Gert U. van Zyl', 'orcid': 'https://orcid.org/0000-0003-3021-5101'}, 'institutions': [{'id': 'https://openalex.org/I107920810', 'display_name': 'National Health Laboratory Service', 'ror': 'https://ror.org/00znvbk37', 'country_code': 'ZA', 'type': 'government', 'lineage': ['https://openalex.org/I107920810']}, {'id': 'https://openalex.org/I26092322', 'display_name': 'Stellenbosch University', 'ror': 'https://ror.org/05bk57929', 'country_code': 'ZA', 'type': 'education', 'lineage': ['https://openalex.org/I26092322']}], 'countries': ['ZA'], 'is_corresponding': False, 'raw_author_name': 'Gert U. Van Zyl', 'raw_affiliation_strings': ['Division of Medical Virology, Stellenbosch University and National Health Laboratory Service (NHLS) Tygerberg, Cape Town, South Africa.'], 'affiliations': [{'raw_affiliation_string': 'Division of Medical Virology, Stellenbosch University and National Health Laboratory Service (NHLS) Tygerberg, Cape Town, South Africa.', 'institution_ids': ['https://openalex.org/I107920810', 'https://openalex.org/I26092322']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5073155285', 'display_name': 'Mary Grace Katusiime', 'orcid': 'https://orcid.org/0000-0002-0468-0600'}, 'institutions': [{'id': 'https://openalex.org/I107920810', 'display_name': 'National Health Laboratory Service', 'ror': 'https://ror.org/00znvbk37', 'country_code': 'ZA', 'type': 'government', 'lineage': ['https://openalex.org/I107920810']}, {'id': 'https://openalex.org/I26092322', 'display_name': 'Stellenbosch University', 'ror': 'https://ror.org/05bk57929', 'country_code': 'ZA', 'type': 'education', 'lineage': ['https://openalex.org/I26092322']}], 'countries': ['ZA'], 'is_corresponding': False, 'raw_author_name': 'Mary Grace Katusiime', 'raw_affiliation_strings': ['Division of Medical Virology, Stellenbosch University and National Health Laboratory Service (NHLS) Tygerberg, Cape Town, South Africa.'], 'affiliations': [{'raw_affiliation_string': 'Division of Medical Virology, Stellenbosch University and National Health Laboratory Service (NHLS) Tygerberg, Cape Town, South Africa.', 'institution_ids': ['https://openalex.org/I107920810', 'https://openalex.org/I26092322']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5027031903', 'display_name': 'Ann Wiegand', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210140884', 'display_name': 'National Cancer Institute', 'ror': 'https://ror.org/040gcmg81', 'country_code': 'US', 'type': 'government', 'lineage': ['https://openalex.org/I1299022934', 'https://openalex.org/I1299303238', 'https://openalex.org/I4210140884']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Ann Wiegand', 'raw_affiliation_strings': ['HIV Dynamics and Replication Program, National Cancer Institute (NCI), Frederick, Maryland, USA.'], 'affiliations': [{'raw_affiliation_string': 'HIV Dynamics and Replication Program, National Cancer Institute (NCI), Frederick, Maryland, USA.', 'institution_ids': ['https://openalex.org/I4210140884']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5014870853', 'display_name': 'William R. McManus', 'orcid': 'https://orcid.org/0000-0002-1461-3903'}, 'institutions': [{'id': 'https://openalex.org/I4210140884', 'display_name': 'National Cancer Institute', 'ror': 'https://ror.org/040gcmg81', 'country_code': 'US', 'type': 'government', 'lineage': ['https://openalex.org/I1299022934', 'https://openalex.org/I1299303238', 'https://openalex.org/I4210140884']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'William R. McManus', 'raw_affiliation_strings': ['HIV Dynamics and Replication Program, National Cancer Institute (NCI), Frederick, Maryland, USA.'], 'affiliations': [{'raw_affiliation_string': 'HIV Dynamics and Replication Program, National Cancer Institute (NCI), Frederick, Maryland, USA.', 'institution_ids': ['https://openalex.org/I4210140884']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5040722690', 'display_name': 'Michael J. Bale', 'orcid': 'https://orcid.org/0000-0002-6899-1459'}, 'institutions': [{'id': 'https://openalex.org/I4210140884', 'display_name': 'National Cancer Institute', 'ror': 'https://ror.org/040gcmg81', 'country_code': 'US', 'type': 'government', 'lineage': ['https://openalex.org/I1299022934', 'https://openalex.org/I1299303238', 'https://openalex.org/I4210140884']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Michael J. Bale', 'raw_affiliation_strings': ['HIV Dynamics and Replication Program, National Cancer Institute (NCI), Frederick, Maryland, USA.'], 'affiliations': [{'raw_affiliation_string': 'HIV Dynamics and Replication Program, National Cancer Institute (NCI), Frederick, Maryland, USA.', 'institution_ids': ['https://openalex.org/I4210140884']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5052131528', 'display_name': 'Elias K. Halvas', 'orcid': 'https://orcid.org/0000-0002-4890-1209'}, 'institutions': [{'id': 'https://openalex.org/I170201317', 'display_name': 'University of Pittsburgh', 'ror': 'https://ror.org/01an3r305', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I170201317']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Elias K. Halvas', 'raw_affiliation_strings': ['Department of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.'], 'affiliations': [{'raw_affiliation_string': 'Department of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.', 'institution_ids': ['https://openalex.org/I170201317']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5077852553', 'display_name': 'Brian T. Luke', 'orcid': 'https://orcid.org/0000-0002-2777-7376'}, 'institutions': [{'id': 'https://openalex.org/I114662689', 'display_name': 'Leidos (United States)', 'ror': 'https://ror.org/012cvds63', 'country_code': 'US', 'type': 'company', 'lineage': ['https://openalex.org/I114662689']}, {'id': 'https://openalex.org/I4396570585', 'display_name': 'Leidos Biomedical Research Inc. (United States)', 'ror': 'https://ror.org/00bardy64', 'country_code': None, 'type': 'company', 'lineage': ['https://openalex.org/I114662689', 'https://openalex.org/I4396570585']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Brian Luke', 'raw_affiliation_strings': ['Advanced Biomedical Computing Center, Leidos Biomedical Research Inc. and Frederick National Laboratories for Cancer Research, Frederick, Maryland, USA.'], 'affiliations': [{'raw_affiliation_string': 'Advanced Biomedical Computing Center, Leidos Biomedical Research Inc. and Frederick National Laboratories for Cancer Research, Frederick, Maryland, USA.', 'institution_ids': ['https://openalex.org/I114662689', 'https://openalex.org/I4396570585']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5040327077', 'display_name': 'Valerie F. Boltz', 'orcid': 'https://orcid.org/0000-0001-8872-5599'}, 'institutions': [{'id': 'https://openalex.org/I4210140884', 'display_name': 'National Cancer Institute', 'ror': 'https://ror.org/040gcmg81', 'country_code': 'US', 'type': 'government', 'lineage': ['https://openalex.org/I1299022934', 'https://openalex.org/I1299303238', 'https://openalex.org/I4210140884']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Valerie F. Boltz', 'raw_affiliation_strings': ['HIV Dynamics and Replication Program, National Cancer Institute (NCI), Frederick, Maryland, USA.'], 'affiliations': [{'raw_affiliation_string': 'HIV Dynamics and Replication Program, National Cancer Institute (NCI), Frederick, Maryland, USA.', 'institution_ids': ['https://openalex.org/I4210140884']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5110699889', 'display_name': 'Jonathan Spindler', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210140884', 'display_name': 'National Cancer Institute', 'ror': 'https://ror.org/040gcmg81', 'country_code': 'US', 'type': 'government', 'lineage': ['https://openalex.org/I1299022934', 'https://openalex.org/I1299303238', 'https://openalex.org/I4210140884']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Jonathan Spindler', 'raw_affiliation_strings': ['HIV Dynamics and Replication Program, National Cancer Institute (NCI), Frederick, Maryland, USA.'], 'affiliations': [{'raw_affiliation_string': 'HIV Dynamics and Replication Program, National Cancer Institute (NCI), Frederick, Maryland, USA.', 'institution_ids': ['https://openalex.org/I4210140884']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5020803338', 'display_name': 'Barbara Laughton', 'orcid': 'https://orcid.org/0000-0001-7260-7723'}, 'institutions': [{'id': 'https://openalex.org/I26092322', 'display_name': 'Stellenbosch University', 'ror': 'https://ror.org/05bk57929', 'country_code': 'ZA', 'type': 'education', 'lineage': ['https://openalex.org/I26092322']}, {'id': 'https://openalex.org/I4210092469', 'display_name': 'Tygerberg Children’s Hospital', 'ror': 'https://ror.org/00je08x63', 'country_code': 'ZA', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210092469']}], 'countries': ['ZA'], 'is_corresponding': False, 'raw_author_name': 'Barbara Laughton', 'raw_affiliation_strings': ["Department Pediatrics and Child Health, Tygerberg Children's Hospital and Family Clinical Research Unit, Stellenbosch University, Cape Town, South Africa."], 'affiliations': [{'raw_affiliation_string': "Department Pediatrics and Child Health, Tygerberg Children's Hospital and Family Clinical Research Unit, Stellenbosch University, Cape Town, South Africa.", 'institution_ids': ['https://openalex.org/I26092322', 'https://openalex.org/I4210092469']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5050560272', 'display_name': 'Susan Engelbrecht', 'orcid': 'https://orcid.org/0000-0002-1318-5994'}, 'institutions': [{'id': 'https://openalex.org/I107920810', 'display_name': 'National Health Laboratory Service', 'ror': 'https://ror.org/00znvbk37', 'country_code': 'ZA', 'type': 'government', 'lineage': ['https://openalex.org/I107920810']}, {'id': 'https://openalex.org/I26092322', 'display_name': 'Stellenbosch University', 'ror': 'https://ror.org/05bk57929', 'country_code': 'ZA', 'type': 'education', 'lineage': ['https://openalex.org/I26092322']}], 'countries': ['ZA'], 'is_corresponding': False, 'raw_author_name': 'Susan Engelbrecht', 'raw_affiliation_strings': ['Division of Medical Virology, Stellenbosch University and National Health Laboratory Service (NHLS) Tygerberg, Cape Town, South Africa.'], 'affiliations': [{'raw_affiliation_string': 'Division of Medical Virology, Stellenbosch University and National Health Laboratory Service (NHLS) Tygerberg, Cape Town, South Africa.', 'institution_ids': ['https://openalex.org/I107920810', 'https://openalex.org/I26092322']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5065227576', 'display_name': 'John M. Coffin', 'orcid': 'https://orcid.org/0000-0003-3856-762X'}, 'institutions': [{'id': 'https://openalex.org/I121934306', 'display_name': 'Tufts University', 'ror': 'https://ror.org/05wvpxv85', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I121934306']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'John M. Coffin', 'raw_affiliation_strings': ['Department of Molecular Biology and Microbiology, Tufts University, Boston,                      Massachusetts, USA.'], 'affiliations': [{'raw_affiliation_string': 'Department of Molecular Biology and Microbiology, Tufts University, Boston,                      Massachusetts, USA.', 'institution_ids': ['https://openalex.org/I121934306']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5011540954', 'display_name': 'Mark F. Cotton', 'orcid': 'https://orcid.org/0000-0003-2559-6034'}, 'institutions': [{'id': 'https://openalex.org/I26092322', 'display_name': 'Stellenbosch University', 'ror': 'https://ror.org/05bk57929', 'country_code': 'ZA', 'type': 'education', 'lineage': ['https://openalex.org/I26092322']}, {'id': 'https://openalex.org/I4210092469', 'display_name': 'Tygerberg Children’s Hospital', 'ror': 'https://ror.org/00je08x63', 'country_code': 'ZA', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210092469']}], 'countries': ['ZA'], 'is_corresponding': False, 'raw_author_name': 'Mark F. Cotton', 'raw_affiliation_strings': ["Department Pediatrics and Child Health, Tygerberg Children's Hospital and Family Clinical Research Unit, Stellenbosch University, Cape Town, South Africa."], 'affiliations': [{'raw_affiliation_string': "Department Pediatrics and Child Health, Tygerberg Children's Hospital and Family Clinical Research Unit, Stellenbosch University, Cape Town, South Africa.", 'institution_ids': ['https://openalex.org/I26092322', 'https://openalex.org/I4210092469']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5101923609', 'display_name': 'Wei Shao', 'orcid': 'https://orcid.org/0000-0002-3662-5753'}, 'institutions': [{'id': 'https://openalex.org/I114662689', 'display_name': 'Leidos (United States)', 'ror': 'https://ror.org/012cvds63', 'country_code': 'US', 'type': 'company', 'lineage': ['https://openalex.org/I114662689']}, {'id': 'https://openalex.org/I4396570585', 'display_name': 'Leidos Biomedical Research Inc. (United States)', 'ror': 'https://ror.org/00bardy64', 'country_code': None, 'type': 'company', 'lineage': ['https://openalex.org/I114662689', 'https://openalex.org/I4396570585']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Wei Shao', 'raw_affiliation_strings': ['Advanced Biomedical Computing Center, Leidos Biomedical Research Inc. and Frederick National Laboratories for Cancer Research, Frederick, Maryland, USA.'], 'affiliations': [{'raw_affiliation_string': 'Advanced Biomedical Computing Center, Leidos Biomedical Research Inc. and Frederick National Laboratories for Cancer Research, Frederick, Maryland, USA.', 'institution_ids': ['https://openalex.org/I114662689', 'https://openalex.org/I4396570585']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5038307269', 'display_name': 'John W. Mellors', 'orcid': 'https://orcid.org/0000-0002-3737-9742'}, 'institutions': [{'id': 'https://openalex.org/I170201317', 'display_name': 'University of Pittsburgh', 'ror': 'https://ror.org/01an3r305', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I170201317']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'John W. Mellors', 'raw_affiliation_strings': ['Department of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.'], 'affiliations': [{'raw_affiliation_string': 'Department of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.', 'institution_ids': ['https://openalex.org/I170201317']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5029362932', 'display_name': 'Mary F. Kearney', 'orcid': 'https://orcid.org/0000-0003-3839-6576'}, 'institutions': [{'id': 'https://openalex.org/I4210140884', 'display_name': 'National Cancer Institute', 'ror': 'https://ror.org/040gcmg81', 'country_code': 'US', 'type': 'government', 'lineage': ['https://openalex.org/I1299022934', 'https://openalex.org/I1299303238', 'https://openalex.org/I4210140884']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Mary F. Kearney', 'raw_affiliation_strings': ['HIV Dynamics and Replication Program, National Cancer Institute (NCI), Frederick, Maryland, USA.'], 'affiliations': [{'raw_affiliation_string': 'HIV Dynamics and Replication Program, National Cancer Institute (NCI), Frederick, Maryland, USA.', 'institution_ids': ['https://openalex.org/I4210140884']}]}], 'institution_assertions': [], 'countries_distinct_count': 2, 'institutions_distinct_count': 8, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': {'value': 5200, 'currency': 'USD', 'value_usd': 5200, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 4.833, 'has_fulltext': True, 'fulltext_origin': 'pdf', 'cited_by_count': 68, 'citation_normalized_percentile': {'value': 0.820796, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 97, 'max': 98}, 'biblio': {'volume': '127', 'issue': '10', 'first_page': '3827', 'last_page': '3834'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10112', 'display_name': 'HIV Research and Treatment', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/2406', 'display_name': 'Virology'}, 'field': {'id': 'https://openalex.org/fields/24', 'display_name': 'Immunology and Microbiology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10112', 'display_name': 'HIV Research and Treatment', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/2406', 'display_name': 'Virology'}, 'field': {'id': 'https://openalex.org/fields/24', 'display_name': 'Immunology and Microbiology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10082', 'display_name': 'HIV/AIDS Research and Interventions', 'score': 0.9992, 'subfield': {'id': 'https://openalex.org/subfields/2725', 'display_name': 'Infectious Diseases'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10526', 'display_name': 'HIV/AIDS drug development and treatment', 'score': 0.9906, 'subfield': {'id': 'https://openalex.org/subfields/2725', 'display_name': 'Infectious Diseases'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/viremia', 'display_name': 'Viremia', 'score': 0.953738}, {'id': 'https://openalex.org/keywords/viral-evolution', 'display_name': 'Viral evolution', 'score': 0.5432078}, {'id': 'https://openalex.org/keywords/replication', 'display_name': 'Replication', 'score': 0.5165314}], 'concepts': [{'id': 'https://openalex.org/C2776185481', 'wikidata': 'https://www.wikidata.org/wiki/Q1425304', 'display_name': 'Viremia', 'level': 3, 'score': 0.953738}, {'id': 'https://openalex.org/C140704245', 'wikidata': 'https://www.wikidata.org/wiki/Q3933202', 'display_name': 'Viral replication', 'level': 3, 'score': 0.7255026}, {'id': 'https://openalex.org/C2993143319', 'wikidata': 'https://www.wikidata.org/wiki/Q583050', 'display_name': 'Antiretroviral therapy', 'level': 4, 'score': 0.67904425}, {'id': 'https://openalex.org/C159047783', 'wikidata': 'https://www.wikidata.org/wiki/Q7215', 'display_name': 'Virology', 'level': 1, 'score': 0.61661863}, {'id': 'https://openalex.org/C8769409', 'wikidata': 'https://www.wikidata.org/wiki/Q2066554', 'display_name': 'Viral evolution', 'level': 4, 'score': 0.5432078}, {'id': 'https://openalex.org/C142462285', 'wikidata': 'https://www.wikidata.org/wiki/Q2528140', 'display_name': 'Viral load', 'level': 3, 'score': 0.53333956}, {'id': 'https://openalex.org/C12590798', 'wikidata': 'https://www.wikidata.org/wiki/Q3933199', 'display_name': 'Replication (statistics)', 'level': 2, 'score': 0.5165314}, {'id': 'https://openalex.org/C3013748606', 'wikidata': 'https://www.wikidata.org/wiki/Q15787', 'display_name': 'Human immunodeficiency virus (HIV)', 'level': 2, 'score': 0.4939862}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.46407205}, {'id': 'https://openalex.org/C203014093', 'wikidata': 'https://www.wikidata.org/wiki/Q101929', 'display_name': 'Immunology', 'level': 1, 'score': 0.41289032}, {'id': 'https://openalex.org/C2522874641', 'wikidata': 'https://www.wikidata.org/wiki/Q808', 'display_name': 'Virus', 'level': 2, 'score': 0.40291098}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.3783577}, {'id': 'https://openalex.org/C54355233', 'wikidata': 'https://www.wikidata.org/wiki/Q7162', 'display_name': 'Genetics', 'level': 1, 'score': 0.23162135}, {'id': 'https://openalex.org/C141231307', 'wikidata': 'https://www.wikidata.org/wiki/Q7020', 'display_name': 'Genome', 'level': 3, 'score': 0.09810728}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D044966', 'descriptor_name': 'Anti-Retroviral Agents', 'qualifier_ui': 'Q000008', 'qualifier_name': 'administration & dosage', 'is_major_topic': True}, {'descriptor_ui': 'D015658', 'descriptor_name': 'HIV Infections', 'qualifier_ui': 'Q000188', 'qualifier_name': 'drug therapy', 'is_major_topic': True}, {'descriptor_ui': 'D015497', 'descriptor_name': 'HIV-1', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': True}, {'descriptor_ui': 'D014779', 'descriptor_name': 'Virus Replication', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': True}, {'descriptor_ui': 'D002648', 'descriptor_name': 'Child', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002675', 'descriptor_name': 'Child, Preschool', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005260', 'descriptor_name': 'Female', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007223', 'descriptor_name': 'Infant', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007231', 'descriptor_name': 'Infant, Newborn', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008297', 'descriptor_name': 'Male', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D014766', 'descriptor_name': 'Viremia', 'qualifier_ui': 'Q000188', 'qualifier_name': 'drug therapy', 'is_major_topic': False}], 'locations_count': 4, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.1172/jci94582', 'pdf_url': 'http://www.jci.org/articles/view/94582/files/pdf', 'source': {'id': 'https://openalex.org/S114430552', 'display_name': 'Journal of Clinical Investigation', 'issn_l': '0021-9738', 'issn': ['0021-9738', '1558-8238'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320279', 'host_organization_name': 'American Society for Clinical Investigation', 'host_organization_lineage': ['https://openalex.org/P4310320279'], 'host_organization_lineage_names': ['American Society for Clinical Investigation'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://europepmc.org/articles/pmc5617669', 'pdf_url': 'https://europepmc.org/articles/pmc5617669?pdf=render', 'source': {'id': 'https://openalex.org/S4306400806', 'display_name': 'Europe PMC (PubMed Central)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1303153112', 'host_organization_name': 'European Bioinformatics Institute', 'host_organization_lineage': ['https://openalex.org/I1303153112'], 'host_organization_lineage_names': ['European Bioinformatics Institute'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5617669', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/28891813', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1172/jci94582', 'pdf_url': 'http://www.jci.org/articles/view/94582/files/pdf', 'source': {'id': 'https://openalex.org/S114430552', 'display_name': 'Journal of Clinical Investigation', 'issn_l': '0021-9738', 'issn': ['0021-9738', '1558-8238'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320279', 'host_organization_name': 'American Society for Clinical Investigation', 'host_organization_lineage': ['https://openalex.org/P4310320279'], 'host_organization_lineage_names': ['American Society for Clinical Investigation'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [{'display_name': 'Good health and well-being', 'id': 'https://metadata.un.org/sdg/3', 'score': 0.85}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 44, 'referenced_works': ['https://openalex.org/W1497870368', 'https://openalex.org/W2002574877', 'https://openalex.org/W2013711784', 'https://openalex.org/W2024070376', 'https://openalex.org/W2045035461', 'https://openalex.org/W2046159404', 'https://openalex.org/W2052959758', 'https://openalex.org/W2056833651', 'https://openalex.org/W2060829964', 'https://openalex.org/W2064140898', 'https://openalex.org/W2064416623', 'https://openalex.org/W2068816405', 'https://openalex.org/W2072913970', 'https://openalex.org/W2090646713', 'https://openalex.org/W2101516953', 'https://openalex.org/W2114538357', 'https://openalex.org/W2115580899', 'https://openalex.org/W2119974226', 'https://openalex.org/W2126603527', 'https://openalex.org/W2135390958', 'https://openalex.org/W2151235890', 'https://openalex.org/W2152365654', 'https://openalex.org/W2154283429', 'https://openalex.org/W2155462089', 'https://openalex.org/W2163515030', 'https://openalex.org/W2164734631', 'https://openalex.org/W2170178664', 'https://openalex.org/W2170219825', 'https://openalex.org/W2170830827', 'https://openalex.org/W2172297142', 'https://openalex.org/W2179998662', 'https://openalex.org/W2263584512', 'https://openalex.org/W2272185077', 'https://openalex.org/W2284414405', 'https://openalex.org/W2330970697', 'https://openalex.org/W2339878931', 'https://openalex.org/W2504810550', 'https://openalex.org/W2512878063', 'https://openalex.org/W2549615728', 'https://openalex.org/W2581762880', 'https://openalex.org/W2598871150', 'https://openalex.org/W2602545542', 'https://openalex.org/W2606857030', 'https://openalex.org/W2793229524'], 'related_works': ['https://openalex.org/W4255695068', 'https://openalex.org/W4249966514', 'https://openalex.org/W4236946429', 'https://openalex.org/W2231521459', 'https://openalex.org/W2086616853', 'https://openalex.org/W2074878346', 'https://openalex.org/W2009307527', 'https://openalex.org/W2002753371', 'https://openalex.org/W1995324211', 'https://openalex.org/W1993025430'], 'abstract_inverted_index': {'It': [0], 'remains': [1], 'controversial': [2], 'whether': [3], 'current': [4, 54], 'antiretroviral': [5], 'therapy': [6], '(ART)': [7], 'fully': [8], 'suppresses': [9], 'the': [10, 28, 47, 146, 158, 176, 184, 196], 'cycles': [11], 'of': [12, 49, 85, 90, 129, 135, 140, 145, 163, 167], 'HIV': [13, 59, 118, 188], 'replication': [14, 21, 52, 119, 189], 'and': [15, 87, 105, 112, 120, 194], 'viral': [16, 51, 72], 'evolution': [17, 142], 'in': [18, 23, 61, 143], 'vivo.': [19], 'If': [20], 'persists': [22], 'sanctuary': [24], 'sites': [25], 'such': [26], 'as': [27, 114], 'lymph': [29], 'nodes,': [30], 'a': [31], 'high': [32], 'priority': [33], 'should': [34], 'be': [35], 'placed': [36], 'on': [37, 53, 152, 165], 'improving': [38], 'ART': [39, 55, 70, 79, 166, 193], 'regimes': [40], 'to': [41, 95, 175, 199], 'target': [42], 'these': [43, 181], 'sites.': [44], 'To': [45], 'investigate': [46], 'question': [48], 'ongoing': [50, 187], 'regimens,': [56], 'we': [57], 'analyzed': [58], 'populations': [60], 'longitudinal': [62], 'samples': [63], 'from': [64], '10': [65], 'HIV-1–infected': [66], 'children': [67, 77, 99, 125, 148], 'who': [68], 'initiated': [69], 'when': [71], 'diversity': [73], 'was': [74], 'low.': [75], 'Eight': [76], 'started': [78], 'at': [80], 'less': [81], 'than': [82], 'ten': [83], 'months': [84], 'age': [86], 'showed': [88, 126], 'suppression': [89, 151], 'plasma': [91], 'viremia': [92, 102, 110, 150], 'for': [93, 103, 117], 'seven': [94], 'nine': [96], 'years.': [97], 'Two': [98], 'had': [100], 'uncontrolled': [101], 'fifteen': [104], 'thirty': [106], 'months,': [107], 'respectively,': [108], 'before': [109], 'suppression,': [111], 'served': [113], 'positive': [115], 'controls': [116], 'evolution.': [121], 'These': [122], 'latter': [123], '2': [124], 'clear': [127], 'evidence': [128, 139], 'virus': [130, 141], 'evolution,': [131], 'whereas': [132], 'multiple': [133], 'methods': [134], 'analysis': [136], 'bore': [137, 172], 'no': [138, 173], 'any': [144], '8': [147], 'with': [149, 157, 192], 'ART.': [153], 'Phylogenetic': [154], 'trees': [155], 'simulated': [156], 'recently': [159], 'reported': [160], 'evolutionary': [161], 'rate': [162], 'HIV-1': [164, 201], '6': [168], '×': [169], '10–4': [170], 'substitutions/site/month': [171], 'resemblance': [174], 'observed': [177], 'data.': [178], 'Taken': [179], 'together,': [180], 'data': [182], 'refute': [183], 'concept': [185], 'that': [186], 'is': [190, 195], 'common': [191], 'major': [197], 'barrier': [198], 'curing': [200], 'infection.': [202]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2753290949', 'counts_by_year': [{'year': 2024, 'cited_by_count': 3}, {'year': 2023, 'cited_by_count': 7}, {'year': 2022, 'cited_by_count': 8}, {'year': 2021, 'cited_by_count': 12}, {'year': 2020, 'cited_by_count': 12}, {'year': 2019, 'cited_by_count': 15}, {'year': 2018, 'cited_by_count': 11}], 'updated_date': '2024-12-15T05:57:58.945623', 'created_date': '2017-09-15'}