Publication Information

{'id': 'https://openalex.org/W2752848087', 'doi': 'https://doi.org/10.1038/s41598-017-11892-9', 'title': 'Effect of efflux pump inhibition on Pseudomonas aeruginosa transcriptome and virulence', 'display_name': 'Effect of efflux pump inhibition on Pseudomonas aeruginosa transcriptome and virulence', 'publication_year': 2017, 'publication_date': '2017-09-06', 'ids': {'openalex': 'https://openalex.org/W2752848087', 'doi': 'https://doi.org/10.1038/s41598-017-11892-9', 'mag': '2752848087', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/28900249', 'pmcid': 'https://www.ncbi.nlm.nih.gov/pmc/articles/5596013'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1038/s41598-017-11892-9', 'pdf_url': 'https://www.nature.com/articles/s41598-017-11892-9.pdf', 'source': {'id': 'https://openalex.org/S196734849', 'display_name': 'Scientific Reports', 'issn_l': '2045-2322', 'issn': ['2045-2322'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310319908', 'host_organization_name': 'Nature Portfolio', 'host_organization_lineage': ['https://openalex.org/P4310319908', 'https://openalex.org/P4310319965'], 'host_organization_lineage_names': ['Nature Portfolio', 'Springer Nature'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'gold', 'oa_url': 'https://www.nature.com/articles/s41598-017-11892-9.pdf', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5020116169', 'display_name': 'Giordano Rampioni', 'orcid': 'https://orcid.org/0000-0002-1735-8565'}, 'institutions': [{'id': 'https://openalex.org/I119003972', 'display_name': 'Roma Tre University', 'ror': 'https://ror.org/05vf0dg29', 'country_code': 'IT', 'type': 'education', 'lineage': ['https://openalex.org/I119003972']}], 'countries': ['IT'], 'is_corresponding': False, 'raw_author_name': 'Giordano Rampioni', 'raw_affiliation_strings': ['Department of Science, University Roma Tre, Rome, Italy'], 'affiliations': [{'raw_affiliation_string': 'Department of Science, University Roma Tre, Rome, Italy', 'institution_ids': ['https://openalex.org/I119003972']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5061741082', 'display_name': 'Cejoice Ramachandran Pillai', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I119003972', 'display_name': 'Roma Tre University', 'ror': 'https://ror.org/05vf0dg29', 'country_code': 'IT', 'type': 'education', 'lineage': ['https://openalex.org/I119003972']}], 'countries': ['IT'], 'is_corresponding': False, 'raw_author_name': 'Cejoice Ramachandran Pillai', 'raw_affiliation_strings': ['Department of Science, University Roma Tre, Rome, Italy'], 'affiliations': [{'raw_affiliation_string': 'Department of Science, University Roma Tre, Rome, Italy', 'institution_ids': ['https://openalex.org/I119003972']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5018121772', 'display_name': 'Francesca Longo', 'orcid': 'https://orcid.org/0000-0002-8733-5959'}, 'institutions': [{'id': 'https://openalex.org/I119003972', 'display_name': 'Roma Tre University', 'ror': 'https://ror.org/05vf0dg29', 'country_code': 'IT', 'type': 'education', 'lineage': ['https://openalex.org/I119003972']}], 'countries': ['IT'], 'is_corresponding': False, 'raw_author_name': 'Francesca Longo', 'raw_affiliation_strings': ['Department of Science, University Roma Tre, Rome, Italy'], 'affiliations': [{'raw_affiliation_string': 'Department of Science, University Roma Tre, Rome, Italy', 'institution_ids': ['https://openalex.org/I119003972']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5020111408', 'display_name': 'Roslen Bondì', 'orcid': 'https://orcid.org/0000-0002-1833-9892'}, 'institutions': [{'id': 'https://openalex.org/I119003972', 'display_name': 'Roma Tre University', 'ror': 'https://ror.org/05vf0dg29', 'country_code': 'IT', 'type': 'education', 'lineage': ['https://openalex.org/I119003972']}], 'countries': ['IT'], 'is_corresponding': False, 'raw_author_name': 'Roslen Bondì', 'raw_affiliation_strings': ['Department of Science, University Roma Tre, Rome, Italy'], 'affiliations': [{'raw_affiliation_string': 'Department of Science, University Roma Tre, Rome, Italy', 'institution_ids': ['https://openalex.org/I119003972']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5057323555', 'display_name': 'Valerio Baldelli', 'orcid': 'https://orcid.org/0000-0001-6698-7061'}, 'institutions': [{'id': 'https://openalex.org/I119003972', 'display_name': 'Roma Tre University', 'ror': 'https://ror.org/05vf0dg29', 'country_code': 'IT', 'type': 'education', 'lineage': ['https://openalex.org/I119003972']}], 'countries': ['IT'], 'is_corresponding': False, 'raw_author_name': 'Valerio Baldelli', 'raw_affiliation_strings': ['Department of Science, University Roma Tre, Rome, Italy'], 'affiliations': [{'raw_affiliation_string': 'Department of Science, University Roma Tre, Rome, Italy', 'institution_ids': ['https://openalex.org/I119003972']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5101955480', 'display_name': 'Marco Messina', 'orcid': 'https://orcid.org/0009-0009-8408-8217'}, 'institutions': [{'id': 'https://openalex.org/I119003972', 'display_name': 'Roma Tre University', 'ror': 'https://ror.org/05vf0dg29', 'country_code': 'IT', 'type': 'education', 'lineage': ['https://openalex.org/I119003972']}], 'countries': ['IT'], 'is_corresponding': False, 'raw_author_name': 'Marco Messina', 'raw_affiliation_strings': ['Department of Science, University Roma Tre, Rome, Italy'], 'affiliations': [{'raw_affiliation_string': 'Department of Science, University Roma Tre, Rome, Italy', 'institution_ids': ['https://openalex.org/I119003972']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5021443870', 'display_name': 'Francesco Imperi', 'orcid': 'https://orcid.org/0000-0001-5080-5665'}, 'institutions': [{'id': 'https://openalex.org/I4210153523', 'display_name': 'Istituto Pasteur', 'ror': 'https://ror.org/051v7w268', 'country_code': 'IT', 'type': 'nonprofit', 'lineage': ['https://openalex.org/I4210153523']}, {'id': 'https://openalex.org/I861853513', 'display_name': 'Sapienza University of Rome', 'ror': 'https://ror.org/02be6w209', 'country_code': 'IT', 'type': 'education', 'lineage': ['https://openalex.org/I861853513']}], 'countries': ['IT'], 'is_corresponding': False, 'raw_author_name': 'Francesco Imperi', 'raw_affiliation_strings': ['Department of Biology and Biotechnology "Charles Darwin", Sapienza University of Rome, Rome, Laboratory affiliated to Istituto Pasteur Italia – Fondazione Cenci Bolognetti, Rome, Italy'], 'affiliations': [{'raw_affiliation_string': 'Department of Biology and Biotechnology "Charles Darwin", Sapienza University of Rome, Rome, Laboratory affiliated to Istituto Pasteur Italia – Fondazione Cenci Bolognetti, Rome, Italy', 'institution_ids': ['https://openalex.org/I4210153523', 'https://openalex.org/I861853513']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5050658340', 'display_name': 'Paolo Visca', 'orcid': 'https://orcid.org/0000-0002-6128-7039'}, 'institutions': [{'id': 'https://openalex.org/I119003972', 'display_name': 'Roma Tre University', 'ror': 'https://ror.org/05vf0dg29', 'country_code': 'IT', 'type': 'education', 'lineage': ['https://openalex.org/I119003972']}], 'countries': ['IT'], 'is_corresponding': False, 'raw_author_name': 'Paolo Visca', 'raw_affiliation_strings': ['Department of Science, University Roma Tre, Rome, Italy'], 'affiliations': [{'raw_affiliation_string': 'Department of Science, University Roma Tre, Rome, Italy', 'institution_ids': ['https://openalex.org/I119003972']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5000004678', 'display_name': 'Livia Leoni', 'orcid': 'https://orcid.org/0000-0002-2046-4297'}, 'institutions': [{'id': 'https://openalex.org/I119003972', 'display_name': 'Roma Tre University', 'ror': 'https://ror.org/05vf0dg29', 'country_code': 'IT', 'type': 'education', 'lineage': ['https://openalex.org/I119003972']}], 'countries': ['IT'], 'is_corresponding': False, 'raw_author_name': 'Livia Leoni', 'raw_affiliation_strings': ['Department of Science, University Roma Tre, Rome, Italy'], 'affiliations': [{'raw_affiliation_string': 'Department of Science, University Roma Tre, Rome, Italy', 'institution_ids': ['https://openalex.org/I119003972']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 3, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': {'value': 1890, 'currency': 'EUR', 'value_usd': 2190, 'provenance': 'doaj'}, 'apc_paid': {'value': 1890, 'currency': 'EUR', 'value_usd': 2190, 'provenance': 'doaj'}, 'fwci': 2.749, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 80, 'citation_normalized_percentile': {'value': 0.799125, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 97, 'max': 98}, 'biblio': {'volume': '7', 'issue': '1', 'first_page': None, 'last_page': None}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10593', 'display_name': 'Bacterial biofilms and quorum sensing', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10593', 'display_name': 'Bacterial biofilms and quorum sensing', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10147', 'display_name': 'Antibiotic Resistance in Bacteria', 'score': 0.9997, 'subfield': {'id': 'https://openalex.org/subfields/1313', 'display_name': 'Molecular Medicine'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10195', 'display_name': 'Antimicrobial Resistance in Staphylococcus', 'score': 0.996, 'subfield': {'id': 'https://openalex.org/subfields/2725', 'display_name': 'Infectious Diseases'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/efflux', 'display_name': 'Efflux', 'score': 0.89818096}, {'id': 'https://openalex.org/keywords/strain', 'display_name': 'Strain (injury)', 'score': 0.47217837}], 'concepts': [{'id': 'https://openalex.org/C60987743', 'wikidata': 'https://www.wikidata.org/wiki/Q1460232', 'display_name': 'Virulence', 'level': 3, 'score': 0.9748243}, {'id': 'https://openalex.org/C2777637488', 'wikidata': 'https://www.wikidata.org/wiki/Q31856', 'display_name': 'Pseudomonas aeruginosa', 'level': 3, 'score': 0.94357586}, {'id': 'https://openalex.org/C200082930', 'wikidata': 'https://www.wikidata.org/wiki/Q22327148', 'display_name': 'Efflux', 'level': 2, 'score': 0.89818096}, {'id': 'https://openalex.org/C89423630', 'wikidata': 'https://www.wikidata.org/wiki/Q7193', 'display_name': 'Microbiology', 'level': 1, 'score': 0.8067173}, {'id': 'https://openalex.org/C118687296', 'wikidata': 'https://www.wikidata.org/wiki/Q905754', 'display_name': 'Quorum sensing', 'level': 4, 'score': 0.7670944}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.67726433}, {'id': 'https://openalex.org/C162317418', 'wikidata': 'https://www.wikidata.org/wiki/Q252857', 'display_name': 'Transcriptome', 'level': 4, 'score': 0.57592857}, {'id': 'https://openalex.org/C523546767', 'wikidata': 'https://www.wikidata.org/wiki/Q10876', 'display_name': 'Bacteria', 'level': 2, 'score': 0.53807193}, {'id': 'https://openalex.org/C501593827', 'wikidata': 'https://www.wikidata.org/wiki/Q12187', 'display_name': 'Antibiotics', 'level': 2, 'score': 0.50453985}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.4825403}, {'id': 'https://openalex.org/C127716648', 'wikidata': 'https://www.wikidata.org/wiki/Q104053', 'display_name': 'Phenotype', 'level': 3, 'score': 0.48034775}, {'id': 'https://openalex.org/C2778022156', 'wikidata': 'https://www.wikidata.org/wiki/Q576145', 'display_name': 'Strain (injury)', 'level': 2, 'score': 0.47217837}, {'id': 'https://openalex.org/C94665300', 'wikidata': 'https://www.wikidata.org/wiki/Q63391344', 'display_name': 'Antibiotic resistance', 'level': 3, 'score': 0.42944643}, {'id': 'https://openalex.org/C54355233', 'wikidata': 'https://www.wikidata.org/wiki/Q7162', 'display_name': 'Genetics', 'level': 1, 'score': 0.19422972}, {'id': 'https://openalex.org/C150194340', 'wikidata': 'https://www.wikidata.org/wiki/Q26972', 'display_name': 'Gene expression', 'level': 3, 'score': 0.14694646}, {'id': 'https://openalex.org/C105702510', 'wikidata': 'https://www.wikidata.org/wiki/Q514', 'display_name': 'Anatomy', 'level': 1, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D004151', 'descriptor_name': 'Dipeptides', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': True}, {'descriptor_ui': 'D026901', 'descriptor_name': 'Membrane Transport Proteins', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D011550', 'descriptor_name': 'Pseudomonas aeruginosa', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': True}, {'descriptor_ui': 'D001426', 'descriptor_name': 'Bacterial Proteins', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D020869', 'descriptor_name': 'Gene Expression Profiling', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015964', 'descriptor_name': 'Gene Expression Regulation, Bacterial', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': False}, {'descriptor_ui': 'D010641', 'descriptor_name': 'Phenotype', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011401', 'descriptor_name': 'Promoter Regions, Genetic', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D059467', 'descriptor_name': 'Transcriptome', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D014774', 'descriptor_name': 'Virulence', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 3, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.1038/s41598-017-11892-9', 'pdf_url': 'https://www.nature.com/articles/s41598-017-11892-9.pdf', 'source': {'id': 'https://openalex.org/S196734849', 'display_name': 'Scientific Reports', 'issn_l': '2045-2322', 'issn': ['2045-2322'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310319908', 'host_organization_name': 'Nature Portfolio', 'host_organization_lineage': ['https://openalex.org/P4310319908', 'https://openalex.org/P4310319965'], 'host_organization_lineage_names': ['Nature Portfolio', 'Springer Nature'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5596013', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/28900249', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1038/s41598-017-11892-9', 'pdf_url': 'https://www.nature.com/articles/s41598-017-11892-9.pdf', 'source': {'id': 'https://openalex.org/S196734849', 'display_name': 'Scientific Reports', 'issn_l': '2045-2322', 'issn': ['2045-2322'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310319908', 'host_organization_name': 'Nature Portfolio', 'host_organization_lineage': ['https://openalex.org/P4310319908', 'https://openalex.org/P4310319965'], 'host_organization_lineage_names': ['Nature Portfolio', 'Springer Nature'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [{'id': 'https://metadata.un.org/sdg/3', 'score': 0.42, 'display_name': 'Good health and well-being'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 52, 'referenced_works': ['https://openalex.org/W1498405965', 'https://openalex.org/W1609096489', 'https://openalex.org/W1972605876', 'https://openalex.org/W1973843350', 'https://openalex.org/W1973911317', 'https://openalex.org/W1978334623', 'https://openalex.org/W1978541321', 'https://openalex.org/W1995709604', 'https://openalex.org/W1999979510', 'https://openalex.org/W2001604062', 'https://openalex.org/W2009469402', 'https://openalex.org/W2016341743', 'https://openalex.org/W2027305039', 'https://openalex.org/W2031738351', 'https://openalex.org/W2032054300', 'https://openalex.org/W2034401300', 'https://openalex.org/W2055918473', 'https://openalex.org/W2057418340', 'https://openalex.org/W2068986902', 'https://openalex.org/W2071865996', 'https://openalex.org/W2097804984', 'https://openalex.org/W2104587686', 'https://openalex.org/W2110035347', 'https://openalex.org/W2110473061', 'https://openalex.org/W2112467720', 'https://openalex.org/W2112856040', 'https://openalex.org/W2112882791', 'https://openalex.org/W2112903691', 'https://openalex.org/W2114570899', 'https://openalex.org/W2119158206', 'https://openalex.org/W2133372744', 'https://openalex.org/W2133444948', 'https://openalex.org/W2135215249', 'https://openalex.org/W2136112723', 'https://openalex.org/W2137215017', 'https://openalex.org/W2142758007', 'https://openalex.org/W2146157756', 'https://openalex.org/W2146292204', 'https://openalex.org/W2147171429', 'https://openalex.org/W2154494532', 'https://openalex.org/W2154619792', 'https://openalex.org/W2166489879', 'https://openalex.org/W2166662833', 'https://openalex.org/W2170382524', 'https://openalex.org/W2171527366', 'https://openalex.org/W2278849149', 'https://openalex.org/W2489596030', 'https://openalex.org/W2511101540', 'https://openalex.org/W2523570153', 'https://openalex.org/W2550514972', 'https://openalex.org/W2597266501', 'https://openalex.org/W2604765699'], 'related_works': ['https://openalex.org/W4321436493', 'https://openalex.org/W4319459883', 'https://openalex.org/W3032191698', 'https://openalex.org/W3030741395', 'https://openalex.org/W3029497197', 'https://openalex.org/W2942672939', 'https://openalex.org/W2726936666', 'https://openalex.org/W2370090518', 'https://openalex.org/W2114076854', 'https://openalex.org/W1486285556'], 'abstract_inverted_index': {'Efflux': [0], 'pumps': [1, 24, 77], 'of': [2, 20, 88, 104, 114, 119, 125, 160, 180, 192], 'the': [3, 18, 92, 105, 136, 144, 158], 'resistance-nodulation-cell-division': [4], '(RND)': [5], 'family': [6], 'increase': [7], 'antibiotic': [8, 21, 56], 'resistance': [9], 'in': [10, 84, 101, 154, 167], 'many': [11], 'bacterial': [12, 32], 'pathogens,': [13], 'representing': [14], 'candidate': [15], 'targets': [16], 'for': [17, 52], 'development': [19], 'adjuvants.': [22], 'RND': [23, 75], 'have': [25], 'also': [26, 41], 'been': [27], 'proposed': [28], 'to': [29, 31, 79, 99, 184], 'contribute': [30, 78], 'infection,': [33, 89], 'implying': [34], 'that': [35, 74, 91, 143], 'efflux': [36, 76], 'pump': [37], 'inhibitors': [38], '(EPIs)': [39], 'could': [40], 'act': [42], 'as': [43, 55, 111, 113], 'anti-virulence': [44, 61, 178], 'drugs.': [45], 'Nevertheless,': [46], 'EPIs': [47, 181], 'are': [48, 182], 'usually': [49], 'investigated': [50], 'only': [51], 'their': [53, 59, 193], 'properties': [54, 179], 'adjuvants,': [57], 'while': [58], 'potential': [60], 'activity': [62], 'is': [63, 72, 97, 129], 'seldom': [64], 'taken': [65], 'into': [66, 188], 'account.': [67], 'In': [68], 'this': [69], 'study': [70], 'it': [71], 'shown': [73], 'Pseudomonas': [80], 'aeruginosa': [81, 107, 151, 176], 'PAO1': [82, 108, 152], 'pathogenicity': [83], 'an': [85], 'insect': [86], 'model': [87], 'and': [90, 124, 139, 169], 'well-characterized': [93], 'EPI': [94], 'Phe-Arg-β-naphthylamide': [95], '(PAβN)': [96], 'able': [98], 'reduce': [100], 'vivo': [102, 155], 'virulence': [103, 127, 162], 'P.': [106, 150, 175], 'laboratory': [109], 'strain,': [110], 'well': [112], 'clinical': [115], 'isolates.': [116], 'The': [117], 'production': [118], 'quorum': [120], 'sensing': [121], '(QS)': [122], 'molecules': [123], 'QS-dependent': [126], 'phenotypes': [128], 'differentially': [130], 'affected': [131], 'by': [132, 147], 'PAβN,': [133], 'depending': [134], 'on': [135], 'strain.': [137], 'Transcriptomic': [138], 'phenotypic': [140], 'analyses': [141], 'showed': [142], 'protection': [145], 'exerted': [146], 'PAβN': [148, 173], 'from': [149], 'infection': [153], 'correlates': [156], 'with': [157], 'down-regulation': [159], 'key': [161], 'genes': [163, 165], '(e.g.': [164], 'involved': [166], 'iron': [168], 'phosphate': [170], 'starvation).': [171], 'Since': [172], 'impacts': [174], 'virulence,': [177], 'worthy': [183], 'be': [185], 'explored,': [186], 'taking': [187], 'account': [189], 'possible': [190], 'strain-specificity': [191], 'activity.': [194]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2752848087', 'counts_by_year': [{'year': 2024, 'cited_by_count': 7}, {'year': 2023, 'cited_by_count': 9}, {'year': 2022, 'cited_by_count': 11}, {'year': 2021, 'cited_by_count': 26}, {'year': 2020, 'cited_by_count': 11}, {'year': 2019, 'cited_by_count': 7}, {'year': 2018, 'cited_by_count': 9}], 'updated_date': '2025-01-12T19:23:38.853162', 'created_date': '2017-09-15'}