Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2750747499', 'doi': 'https://doi.org/10.1016/j.semcdb.2017.08.056', 'title': 'Alternative polyadenylation in the regulation and dysregulation of gene expression', 'display_name': 'Alternative polyadenylation in the regulation and dysregulation of gene expression', 'publication_year': 2017, 'publication_date': '2017-09-02', 'ids': {'openalex': 'https://openalex.org/W2750747499', 'doi': 'https://doi.org/10.1016/j.semcdb.2017.08.056', 'mag': '2750747499', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/28867199'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1016/j.semcdb.2017.08.056', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S105347553', 'display_name': 'Seminars in Cell and Developmental Biology', 'issn_l': '1084-9521', 'issn': ['1084-9521', '1096-3634'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'review', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5015384306', 'display_name': 'Rachael Emily Turner', 'orcid': 'https://orcid.org/0000-0001-9319-4825'}, 'institutions': [{'id': 'https://openalex.org/I56590836', 'display_name': 'Monash University', 'ror': 'https://ror.org/02bfwt286', 'country_code': 'AU', 'type': 'education', 'lineage': ['https://openalex.org/I56590836']}], 'countries': ['AU'], 'is_corresponding': False, 'raw_author_name': 'Rachael Emily Turner', 'raw_affiliation_strings': ['Development and stem cells Program, Monash Biomedicine Discovery Institute and Department of Biochemistry and Molecular Biology, Monash University, Melbourne, Victoria, 3800, Australia'], 'affiliations': [{'raw_affiliation_string': 'Development and stem cells Program, Monash Biomedicine Discovery Institute and Department of Biochemistry and Molecular Biology, Monash University, Melbourne, Victoria, 3800, Australia', 'institution_ids': ['https://openalex.org/I56590836']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5023952057', 'display_name': 'Andrew Pattison', 'orcid': 'https://orcid.org/0000-0001-9417-7461'}, 'institutions': [{'id': 'https://openalex.org/I56590836', 'display_name': 'Monash University', 'ror': 'https://ror.org/02bfwt286', 'country_code': 'AU', 'type': 'education', 'lineage': ['https://openalex.org/I56590836']}], 'countries': ['AU'], 'is_corresponding': False, 'raw_author_name': 'Andrew David Pattison', 'raw_affiliation_strings': ['Development and stem cells Program, Monash Biomedicine Discovery Institute and Department of Biochemistry and Molecular Biology, Monash University, Melbourne, Victoria, 3800, Australia'], 'affiliations': [{'raw_affiliation_string': 'Development and stem cells Program, Monash Biomedicine Discovery Institute and Department of Biochemistry and Molecular Biology, Monash University, Melbourne, Victoria, 3800, Australia', 'institution_ids': ['https://openalex.org/I56590836']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5013708479', 'display_name': 'Traude H. Beilharz', 'orcid': 'https://orcid.org/0000-0002-8942-9502'}, 'institutions': [{'id': 'https://openalex.org/I56590836', 'display_name': 'Monash University', 'ror': 'https://ror.org/02bfwt286', 'country_code': 'AU', 'type': 'education', 'lineage': ['https://openalex.org/I56590836']}], 'countries': ['AU'], 'is_corresponding': True, 'raw_author_name': 'Traude Helene Beilharz', 'raw_affiliation_strings': ['Development and stem cells Program, Monash Biomedicine Discovery Institute and Department of Biochemistry and Molecular Biology, Monash University, Melbourne, Victoria, 3800, Australia'], 'affiliations': [{'raw_affiliation_string': 'Development and stem cells Program, Monash Biomedicine Discovery Institute and Department of Biochemistry and Molecular Biology, Monash University, Melbourne, Victoria, 3800, Australia', 'institution_ids': ['https://openalex.org/I56590836']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 1, 'corresponding_author_ids': ['https://openalex.org/A5013708479'], 'corresponding_institution_ids': ['https://openalex.org/I56590836'], 'apc_list': {'value': 4260, 'currency': 'USD', 'value_usd': 4260, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 0.8, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 55, 'citation_normalized_percentile': {'value': 0.461569, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 96, 'max': 97}, 'biblio': {'volume': '75', 'issue': None, 'first_page': '61', 'last_page': '69'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10604', 'display_name': 'RNA Research and Splicing', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10604', 'display_name': 'RNA Research and Splicing', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T11482', 'display_name': 'RNA modifications and cancer', 'score': 0.9993, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T13157', 'display_name': 'Cancer-related gene regulation', 'score': 0.9977, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/post-transcriptional-regulation', 'display_name': 'Post-transcriptional regulation', 'score': 0.5331451}, {'id': 'https://openalex.org/keywords/translational-regulation', 'display_name': 'Translational regulation', 'score': 0.43469846}], 'concepts': [{'id': 'https://openalex.org/C142575336', 'wikidata': 'https://www.wikidata.org/wiki/Q412148', 'display_name': 'Polyadenylation', 'level': 4, 'score': 0.9280188}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.893808}, {'id': 'https://openalex.org/C22667442', 'wikidata': 'https://www.wikidata.org/wiki/Q3272830', 'display_name': 'Three prime untranslated region', 'level': 5, 'score': 0.76673174}, {'id': 'https://openalex.org/C89604277', 'wikidata': 'https://www.wikidata.org/wiki/Q424345', 'display_name': 'Untranslated region', 'level': 4, 'score': 0.73341227}, {'id': 'https://openalex.org/C162317418', 'wikidata': 'https://www.wikidata.org/wiki/Q252857', 'display_name': 'Transcriptome', 'level': 4, 'score': 0.67511666}, {'id': 'https://openalex.org/C105580179', 'wikidata': 'https://www.wikidata.org/wiki/Q188928', 'display_name': 'Messenger RNA', 'level': 3, 'score': 0.6396565}, {'id': 'https://openalex.org/C149364088', 'wikidata': 'https://www.wikidata.org/wiki/Q185917', 'display_name': 'Translation (biology)', 'level': 4, 'score': 0.612713}, {'id': 'https://openalex.org/C150194340', 'wikidata': 'https://www.wikidata.org/wiki/Q26972', 'display_name': 'Gene expression', 'level': 3, 'score': 0.5530831}, {'id': 'https://openalex.org/C178809742', 'wikidata': 'https://www.wikidata.org/wiki/Q3455913', 'display_name': 'Post-transcriptional regulation', 'level': 4, 'score': 0.5331451}, {'id': 'https://openalex.org/C165864922', 'wikidata': 'https://www.wikidata.org/wiki/Q411391', 'display_name': 'Regulation of gene expression', 'level': 3, 'score': 0.49317116}, {'id': 'https://openalex.org/C95444343', 'wikidata': 'https://www.wikidata.org/wiki/Q7141', 'display_name': 'Cell biology', 'level': 1, 'score': 0.48249912}, {'id': 'https://openalex.org/C62531158', 'wikidata': 'https://www.wikidata.org/wiki/Q21100335', 'display_name': 'Cleavage and polyadenylation specificity factor', 'level': 5, 'score': 0.48043868}, {'id': 'https://openalex.org/C67705224', 'wikidata': 'https://www.wikidata.org/wiki/Q11053', 'display_name': 'RNA', 'level': 3, 'score': 0.46195483}, {'id': 'https://openalex.org/C54355233', 'wikidata': 'https://www.wikidata.org/wiki/Q7162', 'display_name': 'Genetics', 'level': 1, 'score': 0.44923148}, {'id': 'https://openalex.org/C41282012', 'wikidata': 'https://www.wikidata.org/wiki/Q3928341', 'display_name': 'RNA-binding protein', 'level': 4, 'score': 0.44776094}, {'id': 'https://openalex.org/C39685955', 'wikidata': 'https://www.wikidata.org/wiki/Q3455905', 'display_name': 'Translational regulation', 'level': 5, 'score': 0.43469846}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.43441772}, {'id': 'https://openalex.org/C2991743866', 'wikidata': 'https://www.wikidata.org/wiki/Q417379', 'display_name': 'Rna processing', 'level': 4, 'score': 0.43339145}, {'id': 'https://openalex.org/C70721500', 'wikidata': 'https://www.wikidata.org/wiki/Q177005', 'display_name': 'Computational biology', 'level': 1, 'score': 0.34551275}], 'mesh': [{'descriptor_ui': 'D020413', 'descriptor_name': "3' Untranslated Regions", 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': True}, {'descriptor_ui': 'D017398', 'descriptor_name': 'Alternative Splicing', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D005786', 'descriptor_name': 'Gene Expression Regulation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D026723', 'descriptor_name': 'Polyadenylation', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': True}, {'descriptor_ui': 'D020413', 'descriptor_name': "3' Untranslated Regions", 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008957', 'descriptor_name': 'Models, Genetic', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D026723', 'descriptor_name': 'Polyadenylation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D014176', 'descriptor_name': 'Protein Biosynthesis', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D059368', 'descriptor_name': 'RNA Isoforms', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D059368', 'descriptor_name': 'RNA Isoforms', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D020871', 'descriptor_name': 'RNA Stability', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1016/j.semcdb.2017.08.056', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S105347553', 'display_name': 'Seminars in Cell and Developmental Biology', 'issn_l': '1084-9521', 'issn': ['1084-9521', '1096-3634'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/28867199', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'score': 0.45, 'display_name': 'Zero hunger', 'id': 'https://metadata.un.org/sdg/2'}], 'grants': [{'funder': 'https://openalex.org/F4320320971', 'funder_display_name': 'Monash University', 'award_id': 'DP170100569'}, {'funder': 'https://openalex.org/F4320320971', 'funder_display_name': 'Monash University', 'award_id': 'APP1128250'}, {'funder': 'https://openalex.org/F4320334704', 'funder_display_name': 'Australian Research Council', 'award_id': 'DP170100569'}, {'funder': 'https://openalex.org/F4320334704', 'funder_display_name': 'Australian Research Council', 'award_id': 'APP1128250'}, {'funder': 'https://openalex.org/F4320334705', 'funder_display_name': 'National Health and Medical Research Council', 'award_id': 'DP170100569'}, {'funder': 'https://openalex.org/F4320334705', 'funder_display_name': 'National Health and Medical Research Council', 'award_id': 'APP1128250'}], 'datasets': [], 'versions': [], 'referenced_works_count': 112, 'referenced_works': ['https://openalex.org/W1539247107', 'https://openalex.org/W1542927170', 'https://openalex.org/W1673271895', 'https://openalex.org/W1807193345', 'https://openalex.org/W1895804627', 'https://openalex.org/W1909699921', 'https://openalex.org/W1964727443', 'https://openalex.org/W1964828166', 'https://openalex.org/W1969412365', 'https://openalex.org/W1971042181', 'https://openalex.org/W1972570570', 'https://openalex.org/W1973159925', 'https://openalex.org/W1975265095', 'https://openalex.org/W1984397453', 'https://openalex.org/W1984594593', 'https://openalex.org/W1988264905', 'https://openalex.org/W1991230146', 'https://openalex.org/W2000666866', 'https://openalex.org/W2002759338', 'https://openalex.org/W2004070918', 'https://openalex.org/W2005106388', 'https://openalex.org/W2014119967', 'https://openalex.org/W2015663091', 'https://openalex.org/W2016874086', 'https://openalex.org/W2017042783', 'https://openalex.org/W2021678907', 'https://openalex.org/W2027784918', 'https://openalex.org/W2028845751', 'https://openalex.org/W2030011185', 'https://openalex.org/W2035225194', 'https://openalex.org/W2036065307', 'https://openalex.org/W2036464097', 'https://openalex.org/W2038424676', 'https://openalex.org/W2042783076', 'https://openalex.org/W2044648543', 'https://openalex.org/W2045124856', 'https://openalex.org/W2045709965', 'https://openalex.org/W2047935781', 'https://openalex.org/W2052494348', 'https://openalex.org/W2054084236', 'https://openalex.org/W2055034110', 'https://openalex.org/W2055191926', 'https://openalex.org/W2057571594', 'https://openalex.org/W2058872954', 'https://openalex.org/W2065213545', 'https://openalex.org/W2073461718', 'https://openalex.org/W2074114726', 'https://openalex.org/W2079591756', 'https://openalex.org/W2079932405', 'https://openalex.org/W2083699794', 'https://openalex.org/W2083748188', 'https://openalex.org/W2083996291', 'https://openalex.org/W2084813257', 'https://openalex.org/W2088389307', 'https://openalex.org/W2089503287', 'https://openalex.org/W2091095457', 'https://openalex.org/W2093295511', 'https://openalex.org/W2093827499', 'https://openalex.org/W2095930993', 'https://openalex.org/W2097247706', 'https://openalex.org/W2097467166', 'https://openalex.org/W2099915768', 'https://openalex.org/W2105060337', 'https://openalex.org/W2105545925', 'https://openalex.org/W2105879579', 'https://openalex.org/W2106448802', 'https://openalex.org/W2106774938', 'https://openalex.org/W2108264419', 'https://openalex.org/W2109302137', 'https://openalex.org/W2109684789', 'https://openalex.org/W2111730089', 'https://openalex.org/W2115305774', 'https://openalex.org/W2116355524', 'https://openalex.org/W2118031210', 'https://openalex.org/W2118834857', 'https://openalex.org/W2119980799', 'https://openalex.org/W2120755707', 'https://openalex.org/W2123285201', 'https://openalex.org/W2124640147', 'https://openalex.org/W2129429612', 'https://openalex.org/W2132619562', 'https://openalex.org/W2132640619', 'https://openalex.org/W2133932782', 'https://openalex.org/W2140006817', 'https://openalex.org/W2143232699', 'https://openalex.org/W2143993503', 'https://openalex.org/W2145083867', 'https://openalex.org/W2148624148', 'https://openalex.org/W2149146886', 'https://openalex.org/W2151562469', 'https://openalex.org/W2151971476', 'https://openalex.org/W2158634288', 'https://openalex.org/W2159666069', 'https://openalex.org/W2161030070', 'https://openalex.org/W2163741321', 'https://openalex.org/W2163975718', 'https://openalex.org/W2164440878', 'https://openalex.org/W2168558973', 'https://openalex.org/W2168759699', 'https://openalex.org/W2170755007', 'https://openalex.org/W2170808955', 'https://openalex.org/W2172208515', 'https://openalex.org/W2178279848', 'https://openalex.org/W2204797107', 'https://openalex.org/W2237816067', 'https://openalex.org/W2263613603', 'https://openalex.org/W2269883402', 'https://openalex.org/W2302755037', 'https://openalex.org/W2463869186', 'https://openalex.org/W2521303180', 'https://openalex.org/W2530453716', 'https://openalex.org/W2531940442'], 'related_works': ['https://openalex.org/W35524438', 'https://openalex.org/W2885722273', 'https://openalex.org/W2750747499', 'https://openalex.org/W2728347564', 'https://openalex.org/W2415164231', 'https://openalex.org/W2165518330', 'https://openalex.org/W2157467537', 'https://openalex.org/W2086830397', 'https://openalex.org/W2062021343', 'https://openalex.org/W1991230146'], 'abstract_inverted_index': None, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2750747499', 'counts_by_year': [{'year': 2024, 'cited_by_count': 3}, {'year': 2023, 'cited_by_count': 6}, {'year': 2022, 'cited_by_count': 8}, {'year': 2021, 'cited_by_count': 12}, {'year': 2020, 'cited_by_count': 12}, {'year': 2019, 'cited_by_count': 8}, {'year': 2018, 'cited_by_count': 6}], 'updated_date': '2025-01-05T11:12:26.072298', 'created_date': '2017-09-15'}