Abstract: Objectives: To determine how accurately freehand elasticity images and measurements correlate to the pathological appearances and dimensions of breast cancers. Reported series show reoperation rates of as high as 50% when wide local excision is based on conventional breast imaging techniques.Methods: Freehand elasticity images (using real time elasticity software implemented on a Siemens Elegra ultrasound scanner) were obtained the day before surgery. The skin of the breast was marked to allow placement of orientation sutures on the tumour specimen at excision. Histology sections were made in the same plane as imaging planes. The edges of the specimen were examined to ensure tumour extent was accurately measured. The skin marking at imaging, and specimen marking at surgery, allowed ultrasound and specimen image correlation.Results: One of nine cases, of elasticity imaging, under measured maximum tumour diameter (this may have been because tumour extent was greater than the elasticity viewable area). B-mode under measured in seven cases. Seven cases of elasticity imaging had closer correlation to pathology diameters than greyscale imaging. On average greyscale under measured by 20% while elasticity imaging over measured by 14%.Conclusions: Initial results suggest that elasticity imaging provides a more reliable method of assessing tumour extent. Objectives: To determine how accurately freehand elasticity images and measurements correlate to the pathological appearances and dimensions of breast cancers. Reported series show reoperation rates of as high as 50% when wide local excision is based on conventional breast imaging techniques. Methods: Freehand elasticity images (using real time elasticity software implemented on a Siemens Elegra ultrasound scanner) were obtained the day before surgery. The skin of the breast was marked to allow placement of orientation sutures on the tumour specimen at excision. Histology sections were made in the same plane as imaging planes. The edges of the specimen were examined to ensure tumour extent was accurately measured. The skin marking at imaging, and specimen marking at surgery, allowed ultrasound and specimen image correlation. Results: One of nine cases, of elasticity imaging, under measured maximum tumour diameter (this may have been because tumour extent was greater than the elasticity viewable area). B-mode under measured in seven cases. Seven cases of elasticity imaging had closer correlation to pathology diameters than greyscale imaging. On average greyscale under measured by 20% while elasticity imaging over measured by 14%. Conclusions: Initial results suggest that elasticity imaging provides a more reliable method of assessing tumour extent.
Publication Year: 2006
Publication Date: 2006-05-01
Language: en
Type: article
Indexed In: ['crossref']
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