Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2745173311', 'doi': 'https://doi.org/10.18632/oncotarget.20215', 'title': 'High amplification of FGFR1 gene is a delayed poor prognostic factor in early stage ESCC patients', 'display_name': 'High amplification of FGFR1 gene is a delayed poor prognostic factor in early stage ESCC patients', 'publication_year': 2017, 'publication_date': '2017-08-12', 'ids': {'openalex': 'https://openalex.org/W2745173311', 'doi': 'https://doi.org/10.18632/oncotarget.20215', 'mag': '2745173311', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/29088806', 'pmcid': 'https://www.ncbi.nlm.nih.gov/pmc/articles/5650361'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.18632/oncotarget.20215', 'pdf_url': 'http://www.oncotarget.com/index.php?journal=oncotarget&page=article&op=download&path%5B%5D=20215&path%5B%5D=64465', 'source': {'id': 'https://openalex.org/S126644158', 'display_name': 'Oncotarget', 'issn_l': '1949-2553', 'issn': ['1949-2553'], 'is_oa': True, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310316297', 'host_organization_name': 'Impact Journals LLC', 'host_organization_lineage': ['https://openalex.org/P4310316297'], 'host_organization_lineage_names': ['Impact Journals LLC'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'gold', 'oa_url': 'http://www.oncotarget.com/index.php?journal=oncotarget&page=article&op=download&path%5B%5D=20215&path%5B%5D=64465', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5044026422', 'display_name': 'Qi Song', 'orcid': 'https://orcid.org/0000-0002-6077-4388'}, 'institutions': [{'id': 'https://openalex.org/I4210128921', 'display_name': 'The First Affiliated Hospital, Sun Yat-sen University', 'ror': 'https://ror.org/037p24858', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210128921']}, {'id': 'https://openalex.org/I4210127074', 'display_name': 'Zhongshan Hospital', 'ror': 'https://ror.org/032x22645', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210127074']}, {'id': 'https://openalex.org/I24943067', 'display_name': 'Fudan University', 'ror': 'https://ror.org/013q1eq08', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I24943067']}, {'id': 'https://openalex.org/I157773358', 'display_name': 'Sun Yat-sen University', 'ror': 'https://ror.org/0064kty71', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I157773358']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Qi Song', 'raw_affiliation_strings': ['Department of Pathology, Zhongshan Hospital, Fudan University, Shanghai 200032, P. R. China'], 'affiliations': [{'raw_affiliation_string': 'Department of Pathology, Zhongshan Hospital, Fudan University, Shanghai 200032, P. R. China', 'institution_ids': ['https://openalex.org/I4210128921', 'https://openalex.org/I4210127074', 'https://openalex.org/I24943067', 'https://openalex.org/I157773358']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5100678288', 'display_name': 'Yalan Liu', 'orcid': 'https://orcid.org/0000-0002-4901-1670'}, 'institutions': [{'id': 'https://openalex.org/I4210127074', 'display_name': 'Zhongshan Hospital', 'ror': 'https://ror.org/032x22645', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210127074']}, {'id': 'https://openalex.org/I24943067', 'display_name': 'Fudan University', 'ror': 'https://ror.org/013q1eq08', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I24943067']}, {'id': 'https://openalex.org/I157773358', 'display_name': 'Sun Yat-sen University', 'ror': 'https://ror.org/0064kty71', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I157773358']}, {'id': 'https://openalex.org/I4210128921', 'display_name': 'The First Affiliated Hospital, Sun Yat-sen University', 'ror': 'https://ror.org/037p24858', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210128921']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Yalan Liu', 'raw_affiliation_strings': ['Department of Pathology, Zhongshan Hospital, Fudan University, Shanghai 200032, P. R. China'], 'affiliations': [{'raw_affiliation_string': 'Department of Pathology, Zhongshan Hospital, Fudan University, Shanghai 200032, P. R. China', 'institution_ids': ['https://openalex.org/I4210127074', 'https://openalex.org/I24943067', 'https://openalex.org/I157773358', 'https://openalex.org/I4210128921']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5021032300', 'display_name': 'Dongxian Jiang', 'orcid': 'https://orcid.org/0000-0002-0203-0356'}, 'institutions': [{'id': 'https://openalex.org/I4210128921', 'display_name': 'The First Affiliated Hospital, Sun Yat-sen University', 'ror': 'https://ror.org/037p24858', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210128921']}, {'id': 'https://openalex.org/I4210127074', 'display_name': 'Zhongshan Hospital', 'ror': 'https://ror.org/032x22645', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210127074']}, {'id': 'https://openalex.org/I24943067', 'display_name': 'Fudan University', 'ror': 'https://ror.org/013q1eq08', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I24943067']}, {'id': 'https://openalex.org/I157773358', 'display_name': 'Sun Yat-sen University', 'ror': 'https://ror.org/0064kty71', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I157773358']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Dongxian Jiang', 'raw_affiliation_strings': ['Department of Pathology, Zhongshan Hospital, Fudan University, Shanghai 200032, P. R. China'], 'affiliations': [{'raw_affiliation_string': 'Department of Pathology, Zhongshan Hospital, Fudan University, Shanghai 200032, P. R. China', 'institution_ids': ['https://openalex.org/I4210128921', 'https://openalex.org/I4210127074', 'https://openalex.org/I24943067', 'https://openalex.org/I157773358']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5100382773', 'display_name': 'Hai Wang', 'orcid': 'https://orcid.org/0000-0001-6507-5503'}, 'institutions': [{'id': 'https://openalex.org/I4210128921', 'display_name': 'The First Affiliated Hospital, Sun Yat-sen University', 'ror': 'https://ror.org/037p24858', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210128921']}, {'id': 'https://openalex.org/I4210127074', 'display_name': 'Zhongshan Hospital', 'ror': 'https://ror.org/032x22645', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210127074']}, {'id': 'https://openalex.org/I24943067', 'display_name': 'Fudan University', 'ror': 'https://ror.org/013q1eq08', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I24943067']}, {'id': 'https://openalex.org/I157773358', 'display_name': 'Sun Yat-sen University', 'ror': 'https://ror.org/0064kty71', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I157773358']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Haixing Wang', 'raw_affiliation_strings': ['Department of Pathology, Zhongshan Hospital, Fudan University, Shanghai 200032, P. R. China'], 'affiliations': [{'raw_affiliation_string': 'Department of Pathology, Zhongshan Hospital, Fudan University, Shanghai 200032, P. R. China', 'institution_ids': ['https://openalex.org/I4210128921', 'https://openalex.org/I4210127074', 'https://openalex.org/I24943067', 'https://openalex.org/I157773358']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5084031121', 'display_name': 'Jie Huang', 'orcid': 'https://orcid.org/0000-0003-2962-7950'}, 'institutions': [{'id': 'https://openalex.org/I4210128921', 'display_name': 'The First Affiliated Hospital, Sun Yat-sen University', 'ror': 'https://ror.org/037p24858', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210128921']}, {'id': 'https://openalex.org/I4210127074', 'display_name': 'Zhongshan Hospital', 'ror': 'https://ror.org/032x22645', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210127074']}, {'id': 'https://openalex.org/I24943067', 'display_name': 'Fudan University', 'ror': 'https://ror.org/013q1eq08', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I24943067']}, {'id': 'https://openalex.org/I157773358', 'display_name': 'Sun Yat-sen University', 'ror': 'https://ror.org/0064kty71', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I157773358']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Jie Huang', 'raw_affiliation_strings': ['Department of Pathology, Zhongshan Hospital, Fudan University, Shanghai 200032, P. R. China'], 'affiliations': [{'raw_affiliation_string': 'Department of Pathology, Zhongshan Hospital, Fudan University, Shanghai 200032, P. R. China', 'institution_ids': ['https://openalex.org/I4210128921', 'https://openalex.org/I4210127074', 'https://openalex.org/I24943067', 'https://openalex.org/I157773358']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5100626725', 'display_name': 'Yifan Xu', 'orcid': 'https://orcid.org/0000-0002-1573-9217'}, 'institutions': [{'id': 'https://openalex.org/I4210128921', 'display_name': 'The First Affiliated Hospital, Sun Yat-sen University', 'ror': 'https://ror.org/037p24858', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210128921']}, {'id': 'https://openalex.org/I4210127074', 'display_name': 'Zhongshan Hospital', 'ror': 'https://ror.org/032x22645', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210127074']}, {'id': 'https://openalex.org/I24943067', 'display_name': 'Fudan University', 'ror': 'https://ror.org/013q1eq08', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I24943067']}, {'id': 'https://openalex.org/I157773358', 'display_name': 'Sun Yat-sen University', 'ror': 'https://ror.org/0064kty71', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I157773358']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Yifan Xu', 'raw_affiliation_strings': ['Department of Pathology, Zhongshan Hospital, Fudan University, Shanghai 200032, P. R. China'], 'affiliations': [{'raw_affiliation_string': 'Department of Pathology, Zhongshan Hospital, Fudan University, Shanghai 200032, P. R. China', 'institution_ids': ['https://openalex.org/I4210128921', 'https://openalex.org/I4210127074', 'https://openalex.org/I24943067', 'https://openalex.org/I157773358']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5013158517', 'display_name': 'Akesu Sujie', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I24943067', 'display_name': 'Fudan University', 'ror': 'https://ror.org/013q1eq08', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I24943067']}, {'id': 'https://openalex.org/I157773358', 'display_name': 'Sun Yat-sen University', 'ror': 'https://ror.org/0064kty71', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I157773358']}, {'id': 'https://openalex.org/I4210128921', 'display_name': 'The First Affiliated Hospital, Sun Yat-sen University', 'ror': 'https://ror.org/037p24858', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210128921']}, {'id': 'https://openalex.org/I4210127074', 'display_name': 'Zhongshan Hospital', 'ror': 'https://ror.org/032x22645', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210127074']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Akesu Sujie', 'raw_affiliation_strings': ['Department of Pathology, Zhongshan Hospital, Fudan University, Shanghai 200032, P. R. China'], 'affiliations': [{'raw_affiliation_string': 'Department of Pathology, Zhongshan Hospital, Fudan University, Shanghai 200032, P. R. China', 'institution_ids': ['https://openalex.org/I24943067', 'https://openalex.org/I157773358', 'https://openalex.org/I4210128921', 'https://openalex.org/I4210127074']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5076604261', 'display_name': 'Haiying Zeng', 'orcid': 'https://orcid.org/0000-0002-9220-0186'}, 'institutions': [{'id': 'https://openalex.org/I4210128921', 'display_name': 'The First Affiliated Hospital, Sun Yat-sen University', 'ror': 'https://ror.org/037p24858', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210128921']}, {'id': 'https://openalex.org/I4210127074', 'display_name': 'Zhongshan Hospital', 'ror': 'https://ror.org/032x22645', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210127074']}, {'id': 'https://openalex.org/I157773358', 'display_name': 'Sun Yat-sen University', 'ror': 'https://ror.org/0064kty71', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I157773358']}, {'id': 'https://openalex.org/I24943067', 'display_name': 'Fudan University', 'ror': 'https://ror.org/013q1eq08', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I24943067']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Haiying Zeng', 'raw_affiliation_strings': ['Department of Pathology, Zhongshan Hospital, Fudan University, Shanghai 200032, P. R. China'], 'affiliations': [{'raw_affiliation_string': 'Department of Pathology, Zhongshan Hospital, Fudan University, Shanghai 200032, P. R. China', 'institution_ids': ['https://openalex.org/I4210128921', 'https://openalex.org/I4210127074', 'https://openalex.org/I157773358', 'https://openalex.org/I24943067']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5100613195', 'display_name': 'Chen Xu', 'orcid': 'https://orcid.org/0000-0002-0858-945X'}, 'institutions': [{'id': 'https://openalex.org/I4210127074', 'display_name': 'Zhongshan Hospital', 'ror': 'https://ror.org/032x22645', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210127074']}, {'id': 'https://openalex.org/I24943067', 'display_name': 'Fudan University', 'ror': 'https://ror.org/013q1eq08', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I24943067']}, {'id': 'https://openalex.org/I157773358', 'display_name': 'Sun Yat-sen University', 'ror': 'https://ror.org/0064kty71', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I157773358']}, {'id': 'https://openalex.org/I4210128921', 'display_name': 'The First Affiliated Hospital, Sun Yat-sen University', 'ror': 'https://ror.org/037p24858', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210128921']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Chen Xu', 'raw_affiliation_strings': ['Department of Pathology, Zhongshan Hospital, Fudan University, Shanghai 200032, P. R. China'], 'affiliations': [{'raw_affiliation_string': 'Department of Pathology, Zhongshan Hospital, Fudan University, Shanghai 200032, P. R. China', 'institution_ids': ['https://openalex.org/I4210127074', 'https://openalex.org/I24943067', 'https://openalex.org/I157773358', 'https://openalex.org/I4210128921']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5018872547', 'display_name': 'Yingyong Hou', 'orcid': 'https://orcid.org/0000-0001-9156-2305'}, 'institutions': [{'id': 'https://openalex.org/I4210127074', 'display_name': 'Zhongshan Hospital', 'ror': 'https://ror.org/032x22645', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210127074']}, {'id': 'https://openalex.org/I24943067', 'display_name': 'Fudan University', 'ror': 'https://ror.org/013q1eq08', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I24943067']}, {'id': 'https://openalex.org/I157773358', 'display_name': 'Sun Yat-sen University', 'ror': 'https://ror.org/0064kty71', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I157773358']}, {'id': 'https://openalex.org/I4210128921', 'display_name': 'The First Affiliated Hospital, Sun Yat-sen University', 'ror': 'https://ror.org/037p24858', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210128921']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Yingyong Hou', 'raw_affiliation_strings': ['Department of Pathology, School of Basic Medical Sciences & Zhongshan Hospital, Fudan University, Shanghai 200032, P. R. China', 'Department of Pathology, Zhongshan Hospital, Fudan University, Shanghai 200032, P. R. China'], 'affiliations': [{'raw_affiliation_string': 'Department of Pathology, School of Basic Medical Sciences & Zhongshan Hospital, Fudan University, Shanghai 200032, P. R. China', 'institution_ids': ['https://openalex.org/I4210127074', 'https://openalex.org/I24943067', 'https://openalex.org/I157773358', 'https://openalex.org/I4210128921']}, {'raw_affiliation_string': 'Department of Pathology, Zhongshan Hospital, Fudan University, Shanghai 200032, P. R. China', 'institution_ids': ['https://openalex.org/I4210128921', 'https://openalex.org/I4210127074', 'https://openalex.org/I24943067', 'https://openalex.org/I157773358']}]}], 'countries_distinct_count': 1, 'institutions_distinct_count': 4, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 0.536, 'has_fulltext': False, 'cited_by_count': 9, 'citation_normalized_percentile': {'value': 0.813541, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 85, 'max': 86}, 'biblio': {'volume': '8', 'issue': '43', 'first_page': '74539', 'last_page': '74553'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T12287', 'display_name': 'Fibroblast Growth Factor Signaling Pathway', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T12287', 'display_name': 'Fibroblast Growth Factor Signaling Pathway', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T11586', 'display_name': 'Diagnosis and Management of Congenital Diaphragmatic Hernia', 'score': 0.9946, 'subfield': {'id': 'https://openalex.org/subfields/2746', 'display_name': 'Surgery'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10549', 'display_name': 'Neonatal Lung Development and Respiratory Morbidity', 'score': 0.9863, 'subfield': {'id': 'https://openalex.org/subfields/2740', 'display_name': 'Pulmonary and Respiratory Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/fibroblast-growth-factor', 'display_name': 'Fibroblast Growth Factor', 'score': 0.566685}], 'concepts': [{'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.6452561}, {'id': 'https://openalex.org/C146357865', 'wikidata': 'https://www.wikidata.org/wiki/Q1123245', 'display_name': 'Stage (stratigraphy)', 'level': 2, 'score': 0.577258}, {'id': 'https://openalex.org/C143998085', 'wikidata': 'https://www.wikidata.org/wiki/Q162555', 'display_name': 'Oncology', 'level': 1, 'score': 0.5073778}, {'id': 'https://openalex.org/C49418065', 'wikidata': 'https://www.wikidata.org/wiki/Q14914258', 'display_name': 'Fibroblast growth factor receptor 1', 'level': 4, 'score': 0.48239672}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.4792978}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.44237465}, {'id': 'https://openalex.org/C7602840', 'wikidata': 'https://www.wikidata.org/wiki/Q746284', 'display_name': 'Gene duplication', 'level': 3, 'score': 0.4341785}, {'id': 'https://openalex.org/C502942594', 'wikidata': 'https://www.wikidata.org/wiki/Q3421914', 'display_name': 'Cancer research', 'level': 1, 'score': 0.36781365}, {'id': 'https://openalex.org/C60644358', 'wikidata': 'https://www.wikidata.org/wiki/Q128570', 'display_name': 'Bioinformatics', 'level': 1, 'score': 0.33828378}, {'id': 'https://openalex.org/C54355233', 'wikidata': 'https://www.wikidata.org/wiki/Q7162', 'display_name': 'Genetics', 'level': 1, 'score': 0.28149432}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.24944136}, {'id': 'https://openalex.org/C74373430', 'wikidata': 'https://www.wikidata.org/wiki/Q24727126', 'display_name': 'Fibroblast growth factor', 'level': 3, 'score': 0.18899548}, {'id': 'https://openalex.org/C170493617', 'wikidata': 'https://www.wikidata.org/wiki/Q208467', 'display_name': 'Receptor', 'level': 2, 'score': 0.16439131}, {'id': 'https://openalex.org/C151730666', 'wikidata': 'https://www.wikidata.org/wiki/Q7205', 'display_name': 'Paleontology', 'level': 1, 'score': 0.0}], 'mesh': [], 'locations_count': 4, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.18632/oncotarget.20215', 'pdf_url': 'http://www.oncotarget.com/index.php?journal=oncotarget&page=article&op=download&path%5B%5D=20215&path%5B%5D=64465', 'source': {'id': 'https://openalex.org/S126644158', 'display_name': 'Oncotarget', 'issn_l': '1949-2553', 'issn': ['1949-2553'], 'is_oa': True, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310316297', 'host_organization_name': 'Impact Journals LLC', 'host_organization_lineage': ['https://openalex.org/P4310316297'], 'host_organization_lineage_names': ['Impact Journals LLC'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://europepmc.org/articles/pmc5650361', 'pdf_url': 'https://europepmc.org/articles/pmc5650361?pdf=render', 'source': {'id': 'https://openalex.org/S4306400806', 'display_name': 'Europe PMC (PubMed Central)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1303153112', 'host_organization_name': 'European Bioinformatics Institute', 'host_organization_lineage': ['https://openalex.org/I1303153112'], 'host_organization_lineage_names': ['European Bioinformatics Institute'], 'type': 'repository'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5650361', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/29088806', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.18632/oncotarget.20215', 'pdf_url': 'http://www.oncotarget.com/index.php?journal=oncotarget&page=article&op=download&path%5B%5D=20215&path%5B%5D=64465', 'source': {'id': 'https://openalex.org/S126644158', 'display_name': 'Oncotarget', 'issn_l': '1949-2553', 'issn': ['1949-2553'], 'is_oa': True, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310316297', 'host_organization_name': 'Impact Journals LLC', 'host_organization_lineage': ['https://openalex.org/P4310316297'], 'host_organization_lineage_names': ['Impact Journals LLC'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [{'score': 0.56, 'display_name': 'No poverty', 'id': 'https://metadata.un.org/sdg/1'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 35, 'referenced_works': ['https://openalex.org/W1491517465', 'https://openalex.org/W1853436017', 'https://openalex.org/W1862401346', 'https://openalex.org/W1960850967', 'https://openalex.org/W1964015222', 'https://openalex.org/W1976651544', 'https://openalex.org/W1980448975', 'https://openalex.org/W1982403224', 'https://openalex.org/W1989169759', 'https://openalex.org/W2005399294', 'https://openalex.org/W2019105683', 'https://openalex.org/W2020534880', 'https://openalex.org/W2028835984', 'https://openalex.org/W2054606083', 'https://openalex.org/W2056983875', 'https://openalex.org/W2071193240', 'https://openalex.org/W2075453277', 'https://openalex.org/W2076356585', 'https://openalex.org/W2081855695', 'https://openalex.org/W2096019143', 'https://openalex.org/W2100439220', 'https://openalex.org/W2104812730', 'https://openalex.org/W2106787323', 'https://openalex.org/W2109020001', 'https://openalex.org/W2129138183', 'https://openalex.org/W2153089464', 'https://openalex.org/W2159060826', 'https://openalex.org/W2164986334', 'https://openalex.org/W2260536780', 'https://openalex.org/W2272984102', 'https://openalex.org/W2342804478', 'https://openalex.org/W2368819226', 'https://openalex.org/W2401279717', 'https://openalex.org/W2595713273', 'https://openalex.org/W4249441028'], 'related_works': ['https://openalex.org/W4388014327', 'https://openalex.org/W4328050637', 'https://openalex.org/W2776829638', 'https://openalex.org/W2367076742', 'https://openalex.org/W2349742942', 'https://openalex.org/W2202284674', 'https://openalex.org/W2130968561', 'https://openalex.org/W2115382138', 'https://openalex.org/W2064495883', 'https://openalex.org/W1883409887'], 'abstract_inverted_index': {'//': [0], 'Qi': [1], 'Song': [2], '1,': [3, 8, 41], '*': [4, 9, 75], ',': [5, 10, 14, 18, 22, 26, 30, 34], 'Yalan': [6], 'Liu': [7], 'Dongxian': [11], 'Jiang': [12], '1': [13, 17, 21, 25, 29, 33, 37, 43, 127], 'Haixing': [15], 'Wang': [16], 'Jie': [19], 'Huang': [20], 'Yifan': [23], 'Xu': [24, 36], 'Akesu': [27], 'Sujie': [28], 'Haiying': [31], 'Zeng': [32], 'Chen': [35, 90], 'and': [38, 149, 177, 256, 274, 281, 296, 343, 355, 409, 418], 'Yingyong': [39, 86], 'Hou': [40], '2': [42, 56], 'Department': [44, 57], 'of': [45, 58, 61, 121, 141, 153, 180, 203, 209, 218, 232, 248, 398, 407], 'Pathology,': [46, 59], 'Zhongshan': [47, 66], 'Hospital,': [48, 67], 'Fudan': [49, 68], 'University,': [50, 69], 'Shanghai': [51, 70], '200032,': [52, 71], 'P.': [53, 72], 'R.': [54, 73], 'China': [55, 74], 'School': [60], 'Basic': [62], 'Medical': [63], 'Sciences': [64], '&': [65], 'These': [76], 'authors': [77], 'have': [78], 'contributed': [79], 'equally': [80], 'to': [81, 133, 136, 145, 263, 301], 'this': [82, 142, 318], 'work': [83], 'Correspondence': [84], 'to:': [85], 'Hou,': [87], 'email:': [88, 92], '[email protected]': [89], 'Xu,': [91], '[email protected]': [93], 'Keywords:': [94], 'FGFR1': [95, 129, 154, 188, 192, 199, 210, 224, 235, 243, 287, 303, 307, 347, 359, 390, 401], 'high': [96, 189, 193, 270, 288, 348, 391, 402], 'amplification,': [97, 271, 273], 'clinical': [98], 'stage,': [99], 'disease': [100], 'free': [101], 'survival': [102, 294, 298], 'time,': [103], 'prognostic': [104, 151], 'marker,': [105], 'ESCC': [106, 420], 'Received:': [107], 'October': [108], '17,': [109], '2016': [110], 'Accepted:': [111], 'June': [112], '29,': [113], '2017': [114, 118], 'Published:': [115], 'August': [116], '12,': [117], 'ABSTRACT': [119], 'Amplification': [120], 'the': [122, 147, 150, 178, 286, 302, 346, 358], 'fibroblast': [123], 'growth': [124], 'factor': [125], 'receptor': [126], '(': [128, 191, 306], ')': [130, 194, 309], 'is': [131], 'believed': [132], 'predict': [134], 'response': [135], 'FGFR': [137], 'inhibitors.': [138], 'The': [139], 'aim': [140], 'study': [143], 'was': [144, 195, 238, 320], 'investigate': [146], 'frequency': [148], 'impact': [152], 'amplification': [155, 190, 237], 'in': [156, 168, 229, 245, 278, 362, 387, 404, 415], 'patients': [157, 185, 323, 337, 365, 386], 'with': [158, 186, 253, 324, 352, 373], 'resected': [159], 'esophageal': [160], 'squamous': [161], 'cell': [162, 212], 'carcinoma': [163], '(ESCC)': [164], 'by': [165, 197, 240], 'using': [166], 'fluorescent': [167], 'situ': [169], 'hybridization.': [170], 'Microarrayed': [171], 'paraffin': [172], 'embedded': [173], 'blocks': [174], 'were': [175, 261, 276, 338], 'constructed,': [176], 'cohort': [179], 'tissues': [181], 'came': [182], 'from': [183], '506': [184, 268], 'ESCC.': [187], 'defined': [196, 239], 'an': [198], '/centromere': [200], '8': [201], 'ratio': [202], '≥': [204, 214, 222, 230, 241, 246, 326, 375], '2.0,': [205], 'or': [206, 216, 226], 'average': [207], 'number': [208], 'signals/tumor': [211], 'nucleus': [213], '6.0,': [215], 'percentage': [217], 'tumor': [219], 'cells': [220], 'containing': [221], '15': [223], 'signals,': [225], 'large': [227], 'cluster': [228], '10%': [231], 'cancer': [233, 249], 'cells.': [234, 250], 'low': [236, 272, 304], '5': [242], 'signals': [244], '50%': [247], 'Kaplan-Meier': [251], 'curves': [252], 'log-rank': [254], 'tests': [255], 'Cox': [257], 'proportional': [258], 'hazards': [259], 'model': [260], 'used': [262], 'analyze': [264], "patients'": [265], 'survival.': [266], 'Among': [267], 'patients,': [269], 'disomy': [275], 'detected': [277], '8.7%,': [279], '3.6%': [280], '87.7%,': [282], 'respectively.': [283], 'In': [284], 'general,': [285], 'group': [289, 310, 349, 361], 'trended': [290], 'towards': [291], 'worse': [292], 'disease-free': [293], '(DFS)': [295], 'overall': [297], '(OS)': [299], 'compared': [300], 'amplification/disomy': [305], 'low/disomy': [308, 360], '(DFS,': [311, 329, 366, 378], 'P': [312, 315, 330, 333, 367, 370, 379, 382], '=0.108;': [313], 'OS,': [314, 332, 369, 381], '=0.112),': [316], 'but': [317], 'trend': [319], 'amplified': [321], 'for': [322, 385], 'DFS': [325, 354, 374, 399], '30': [327, 376], 'months': [328, 377], '=0.009;': [331], '=0.007).': [334], 'Furthermore,': [335], 'when': [336], 'stratified': [339], 'into': [340], 'stage': [341, 344, 363, 388, 416], 'I-II': [342, 364], 'III-IV,': [345, 389], 'directly': [350], 'presented': [351], 'adverse': [353], 'OS': [356], 'than': [357], '=0.019;': [368], '=0.034),': [371], 'especially': [372], '=0.002;': [380], '=0.001).': [383], 'However,': [384], 'had': [392], 'no': [393], 'effect': [394], 'on': [395], 'prognosis': [396, 414], 'regardless': [397], 'time.': [400], 'occurs': [403], 'a': [405], 'minority': [406], 'ESCC,': [408], 'it': [410], 'predicts': [411], 'delayed': [412], 'poor': [413], 'I': [417], 'II': [419], 'patients.': [421]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2745173311', 'counts_by_year': [{'year': 2024, 'cited_by_count': 1}, {'year': 2023, 'cited_by_count': 1}, {'year': 2022, 'cited_by_count': 1}, {'year': 2021, 'cited_by_count': 1}, {'year': 2020, 'cited_by_count': 1}, {'year': 2019, 'cited_by_count': 2}, {'year': 2018, 'cited_by_count': 2}], 'updated_date': '2024-09-01T05:21:15.020992', 'created_date': '2017-08-17'}