Abstract CT131: A randomized (RCT) phase II study of oncolytic reovirus (pelareorep ) plus standard weekly paclitaxel (P) as therapy for metastatic breast cancer (mBC)

Name: Work Video:
Duration: 3 min 30 s
Vanessa Bernstein; Susan Ellard; Susan Dent; Karen A. Gelmon; Sukhbinder Dhesy‐Thind; Mihaela Mates; Muhammed Salim; Lawrence Panasci; Xinni Song; Mark Clemons; Dongsheng Tu; Linda Hagerman; Lesley Seymour
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'adverse': [401], 'events': [402], '(AE)': [403], 'considered,': [405], 'only': [406], 'incidence': [408], 'fatigue': [410], '≥10%': [414, 432], '(16%': [415], 'on': [416], 'vs': [419, 439, 449, 469, 491], '13%,': [420], 'B,': [422, 442, 472], 'p=0.76).': [423], 'Hematologic': [424], 'effects': [429], 'observed': [430], 'included': [434], 'lymphopenia': [435], '(5%': [436], '18%': [440], 'p=0.08),': [443], 'neutropenia': [445], '(23%': [446], '26%': [450], 'B;': [452], 'p=0.8).': [453], 'There': [454, 474], 'difference': [459], '(0%': [466], '13%': [470], 'p=0.03).': [473], 'related': [478], 'deaths.': [479], 'Conclusions:': [480], 'first,': [482], 'II,': [484], 'did': [499], 'not': [500], 'meet': [501], 'its': [502], 'primary': [503], 'PFS.': [506], 'Despite': [507], 'similar': [508], 'RR': [511], 'there': [512], 'pts.': [524], 'Given': [525], 'these': [526], 'data,': [527], 'further': [528], 'exploration': [529], 'role': [532], 'may': [539], 'be': [540], 'interest.': [542], 'Citation': [543], 'Format:': [544], 'Vanessa': [545], 'Bernstein,': [546], 'Susan': [547, 549], 'Ellard,': [548], 'F.': [550], 'Dent,': [551], 'Karen': [552], 'A.': [553], 'Gelmon,': [554], 'Sukhbinder': [555], 'K.': [556], 'Dhesy-Thind,': [557], 'Mihaela': [558], 'Mates,': [559], 'Muhammed': [560], 'Salim,': [561], 'Lawrence': [562], 'Panasci,': [563], 'Xinni': [564], 'Song,': [565], 'Mark': [566], 'Clemons,': [567], 'Dongsheng': [568], 'Tu,': [569], 'Linda': [570], 'J.': [571], 'Hagerman,': [572], 'Lesley': [573], 'Seymour.': [574], '(RCT)': [577], 'oncolytic': [582], '(pelareorep': [584], ')': [585], 'standard': [587], 'weekly': [588], 'paclitaxel': [589], '(P)': [590], 'therapy': [592], 'metastatic': [594], 'breast': [595], 'cancer': [596], '(mBC)': [597], '[abstract].': [598], 'In:': [599], 'Proceedings': [600], 'American': [603], 'Association': [604], 'Cancer': [606, 619], 'Research': [607], 'Annual': [608], 'Meeting': [609], '2017;': [610], '2017': [611], 'Apr': [612], '1-5;': [613], 'Washington,': [614], 'DC.': [615], 'Philadelphia': [616], '(PA):': [617], 'AACR;': [618], 'Res': [620], '2017;77(13': [621], 'Suppl):Abstract': [622], 'nr': [623], 'CT131.': [624], 'doi:10.1158/1538-7445.AM2017-CT131': [625]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2741423221', 'counts_by_year': [{'year': 2020, 'cited_by_count': 2}, {'year': 2018, 'cited_by_count': 1}, {'year': 2017, 'cited_by_count': 1}], 'updated_date': '2024-12-12T10:16:37.281273', 'created_date': '2017-08-08'}
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