Publication Information

{'id': 'https://openalex.org/W2741158063', 'doi': 'https://doi.org/10.1158/1538-7445.am2017-4702', 'title': 'Abstract 4702: PD-L1 blockade in preclinical models of <i>PTEN</i>-deficient prostate cancer', 'display_name': 'Abstract 4702: PD-L1 blockade in preclinical models of <i>PTEN</i>-deficient prostate cancer', 'publication_year': 2017, 'publication_date': '2017-07-01', 'ids': {'openalex': 'https://openalex.org/W2741158063', 'doi': 'https://doi.org/10.1158/1538-7445.am2017-4702', 'mag': '2741158063'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1158/1538-7445.am2017-4702', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S168522863', 'display_name': 'Cancer Research', 'issn_l': '0008-5472', 'issn': ['0008-5472', '1538-7445'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320273', 'host_organization_name': 'American Association for Cancer Research', 'host_organization_lineage': ['https://openalex.org/P4310320273'], 'host_organization_lineage_names': ['American Association for Cancer Research'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5051123041', 'display_name': 'Marco A. De Velasco', 'orcid': 'https://orcid.org/0000-0002-4011-6572'}, 'institutions': [{'id': 'https://openalex.org/I916559398', 'display_name': 'Kindai University', 'ror': 'https://ror.org/05kt9ap64', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I916559398']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Marco A. De Velasco', 'raw_affiliation_strings': ['1Kindai University Faculty of Medicine, Osaka-Sayama, Japan;'], 'affiliations': [{'raw_affiliation_string': '1Kindai University Faculty of Medicine, Osaka-Sayama, Japan;', 'institution_ids': ['https://openalex.org/I916559398']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5083740330', 'display_name': 'Yurie Kura', 'orcid': 'https://orcid.org/0009-0000-8785-3177'}, 'institutions': [{'id': 'https://openalex.org/I916559398', 'display_name': 'Kindai University', 'ror': 'https://ror.org/05kt9ap64', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I916559398']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Yurie Kura', 'raw_affiliation_strings': ['1Kindai University Faculty of Medicine, Osaka-Sayama, Japan;'], 'affiliations': [{'raw_affiliation_string': '1Kindai University Faculty of Medicine, Osaka-Sayama, Japan;', 'institution_ids': ['https://openalex.org/I916559398']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5047104997', 'display_name': 'Naomi Ando', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I916559398', 'display_name': 'Kindai University', 'ror': 'https://ror.org/05kt9ap64', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I916559398']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Naomi Ando', 'raw_affiliation_strings': ['1Kindai University Faculty of Medicine, Osaka-Sayama, Japan;'], 'affiliations': [{'raw_affiliation_string': '1Kindai University Faculty of Medicine, Osaka-Sayama, Japan;', 'institution_ids': ['https://openalex.org/I916559398']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5015519992', 'display_name': 'Noriko Sato', 'orcid': 'https://orcid.org/0000-0002-9372-1725'}, 'institutions': [{'id': 'https://openalex.org/I916559398', 'display_name': 'Kindai University', 'ror': 'https://ror.org/05kt9ap64', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I916559398']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Noriko Sato', 'raw_affiliation_strings': ['1Kindai University Faculty of Medicine, Osaka-Sayama, Japan;'], 'affiliations': [{'raw_affiliation_string': '1Kindai University Faculty of Medicine, Osaka-Sayama, Japan;', 'institution_ids': ['https://openalex.org/I916559398']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5015524135', 'display_name': 'Kazuko Sakai', 'orcid': 'https://orcid.org/0000-0003-1822-2720'}, 'institutions': [{'id': 'https://openalex.org/I916559398', 'display_name': 'Kindai University', 'ror': 'https://ror.org/05kt9ap64', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I916559398']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Kazuko Sakai', 'raw_affiliation_strings': ['1Kindai University Faculty of Medicine, Osaka-Sayama, Japan;'], 'affiliations': [{'raw_affiliation_string': '1Kindai University Faculty of Medicine, Osaka-Sayama, Japan;', 'institution_ids': ['https://openalex.org/I916559398']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5000275517', 'display_name': 'Barry R. Davies', 'orcid': 'https://orcid.org/0000-0002-5414-9113'}, 'institutions': [{'id': 'https://openalex.org/I105036370', 'display_name': 'AstraZeneca (United Kingdom)', 'ror': 'https://ror.org/04r9x1a08', 'country_code': 'GB', 'type': 'company', 'lineage': ['https://openalex.org/I105036370']}], 'countries': ['GB'], 'is_corresponding': False, 'raw_author_name': 'Barry R. Davies', 'raw_affiliation_strings': ['2AstraZeneca, Macclesfield, United Kingdom;'], 'affiliations': [{'raw_affiliation_string': '2AstraZeneca, Macclesfield, United Kingdom;', 'institution_ids': ['https://openalex.org/I105036370']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5101767875', 'display_name': 'Koichi Sugimoto', 'orcid': 'https://orcid.org/0000-0001-6627-9794'}, 'institutions': [{'id': 'https://openalex.org/I916559398', 'display_name': 'Kindai University', 'ror': 'https://ror.org/05kt9ap64', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I916559398']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Koichi Sugimoto', 'raw_affiliation_strings': ['1Kindai University Faculty of Medicine, Osaka-Sayama, Japan;'], 'affiliations': [{'raw_affiliation_string': '1Kindai University Faculty of Medicine, Osaka-Sayama, Japan;', 'institution_ids': ['https://openalex.org/I916559398']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5103082965', 'display_name': 'Masahiro Nozawa', 'orcid': 'https://orcid.org/0000-0001-9950-4636'}, 'institutions': [{'id': 'https://openalex.org/I916559398', 'display_name': 'Kindai University', 'ror': 'https://ror.org/05kt9ap64', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I916559398']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Masahiro Nozawa', 'raw_affiliation_strings': ['1Kindai University Faculty of Medicine, Osaka-Sayama, Japan;'], 'affiliations': [{'raw_affiliation_string': '1Kindai University Faculty of Medicine, Osaka-Sayama, Japan;', 'institution_ids': ['https://openalex.org/I916559398']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5047840224', 'display_name': 'Kazuhiro Yoshimura', 'orcid': 'https://orcid.org/0000-0002-6598-0391'}, 'institutions': [{'id': 'https://openalex.org/I916559398', 'display_name': 'Kindai University', 'ror': 'https://ror.org/05kt9ap64', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I916559398']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Kazuhiro Yoshimura', 'raw_affiliation_strings': ['1Kindai University Faculty of Medicine, Osaka-Sayama, Japan;'], 'affiliations': [{'raw_affiliation_string': '1Kindai University Faculty of Medicine, Osaka-Sayama, Japan;', 'institution_ids': ['https://openalex.org/I916559398']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5061277451', 'display_name': 'Kazuhiro Yoshikawa', 'orcid': 'https://orcid.org/0000-0002-8778-1174'}, 'institutions': [{'id': 'https://openalex.org/I16528096', 'display_name': 'Aichi Medical University', 'ror': 'https://ror.org/02h6cs343', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I16528096']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Kazuhiro Yoshikawa', 'raw_affiliation_strings': ['3Aichi Medical University, Nagakute, Japan.'], 'affiliations': [{'raw_affiliation_string': '3Aichi Medical University, Nagakute, Japan.', 'institution_ids': ['https://openalex.org/I16528096']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5004282323', 'display_name': 'Kazuto Nishio', 'orcid': 'https://orcid.org/0000-0002-8275-0846'}, 'institutions': [{'id': 'https://openalex.org/I916559398', 'display_name': 'Kindai University', 'ror': 'https://ror.org/05kt9ap64', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I916559398']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Kazuto Nishio', 'raw_affiliation_strings': ['1Kindai University Faculty of Medicine, Osaka-Sayama, Japan;'], 'affiliations': [{'raw_affiliation_string': '1Kindai University Faculty of Medicine, Osaka-Sayama, Japan;', 'institution_ids': ['https://openalex.org/I916559398']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5058934672', 'display_name': 'Hirotsugu Uemura', 'orcid': 'https://orcid.org/0000-0002-3665-9523'}, 'institutions': [{'id': 'https://openalex.org/I916559398', 'display_name': 'Kindai University', 'ror': 'https://ror.org/05kt9ap64', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I916559398']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Hirotsugu Uemura', 'raw_affiliation_strings': ['1Kindai University Faculty of Medicine, Osaka-Sayama, Japan;'], 'affiliations': [{'raw_affiliation_string': '1Kindai University Faculty of Medicine, Osaka-Sayama, Japan;', 'institution_ids': ['https://openalex.org/I916559398']}]}], 'institution_assertions': [], 'countries_distinct_count': 2, 'institutions_distinct_count': 3, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 0.214, 'has_fulltext': False, 'cited_by_count': 7, 'citation_normalized_percentile': {'value': 0.686501, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 82, 'max': 83}, 'biblio': {'volume': '77', 'issue': '13_Supplement', 'first_page': '4702', 'last_page': '4702'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10543', 'display_name': 'Prostate Cancer Treatment and Research', 'score': 0.9962, 'subfield': {'id': 'https://openalex.org/subfields/2740', 'display_name': 'Pulmonary and Respiratory Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10543', 'display_name': 'Prostate Cancer Treatment and Research', 'score': 0.9962, 'subfield': {'id': 'https://openalex.org/subfields/2740', 'display_name': 'Pulmonary and Respiratory Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10158', 'display_name': 'Cancer Immunotherapy and Biomarkers', 'score': 0.9818, 'subfield': {'id': 'https://openalex.org/subfields/2730', 'display_name': 'Oncology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10580', 'display_name': 'Immunotherapy and Immune Responses', 'score': 0.9522, 'subfield': {'id': 'https://openalex.org/subfields/2403', 'display_name': 'Immunology'}, 'field': {'id': 'https://openalex.org/fields/24', 'display_name': 'Immunology and Microbiology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/immune-checkpoint', 'display_name': 'Immune checkpoint', 'score': 0.55102384}], 'concepts': [{'id': 'https://openalex.org/C2780192828', 'wikidata': 'https://www.wikidata.org/wiki/Q181257', 'display_name': 'Prostate cancer', 'level': 3, 'score': 0.82159185}, {'id': 'https://openalex.org/C2777609662', 'wikidata': 'https://www.wikidata.org/wiki/Q416356', 'display_name': 'PTEN', 'level': 4, 'score': 0.735612}, {'id': 'https://openalex.org/C502942594', 'wikidata': 'https://www.wikidata.org/wiki/Q3421914', 'display_name': 'Cancer research', 'level': 1, 'score': 0.63940495}, {'id': 'https://openalex.org/C8891405', 'wikidata': 'https://www.wikidata.org/wiki/Q1059', 'display_name': 'Immune system', 'level': 2, 'score': 0.59294856}, {'id': 'https://openalex.org/C2779256933', 'wikidata': 'https://www.wikidata.org/wiki/Q58929', 'display_name': 'Castration', 'level': 3, 'score': 0.5847071}, {'id': 'https://openalex.org/C2776235491', 'wikidata': 'https://www.wikidata.org/wiki/Q9625', 'display_name': 'Prostate', 'level': 3, 'score': 0.57931113}, {'id': 'https://openalex.org/C2780851360', 'wikidata': 'https://www.wikidata.org/wiki/Q21686041', 'display_name': 'Immune checkpoint', 'level': 4, 'score': 0.55102384}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.51995265}, {'id': 'https://openalex.org/C2777701055', 'wikidata': 'https://www.wikidata.org/wiki/Q1427096', 'display_name': 'Immunotherapy', 'level': 3, 'score': 0.50739425}, {'id': 'https://openalex.org/C2778468042', 'wikidata': 'https://www.wikidata.org/wiki/Q273976', 'display_name': 'Blockade', 'level': 3, 'score': 0.47565147}, {'id': 'https://openalex.org/C2776107976', 'wikidata': 'https://www.wikidata.org/wiki/Q1786433', 'display_name': 'Tumor microenvironment', 'level': 3, 'score': 0.46049124}, {'id': 'https://openalex.org/C16930146', 'wikidata': 'https://www.wikidata.org/wiki/Q4381253', 'display_name': 'Stromal cell', 'level': 2, 'score': 0.4414214}, {'id': 'https://openalex.org/C121608353', 'wikidata': 'https://www.wikidata.org/wiki/Q12078', 'display_name': 'Cancer', 'level': 2, 'score': 0.40847975}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.33252755}, {'id': 'https://openalex.org/C203014093', 'wikidata': 'https://www.wikidata.org/wiki/Q101929', 'display_name': 'Immunology', 'level': 1, 'score': 0.29834044}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.26836467}, {'id': 'https://openalex.org/C62478195', 'wikidata': 'https://www.wikidata.org/wiki/Q828130', 'display_name': 'Signal transduction', 'level': 2, 'score': 0.21859917}, {'id': 'https://openalex.org/C170493617', 'wikidata': 'https://www.wikidata.org/wiki/Q208467', 'display_name': 'Receptor', 'level': 2, 'score': 0.20697701}, {'id': 'https://openalex.org/C86554907', 'wikidata': 'https://www.wikidata.org/wiki/Q285613', 'display_name': 'PI3K/AKT/mTOR pathway', 'level': 3, 'score': 0.16013557}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.0}, {'id': 'https://openalex.org/C71315377', 'wikidata': 'https://www.wikidata.org/wiki/Q11364', 'display_name': 'Hormone', 'level': 2, 'score': 0.0}], 'mesh': [], 'locations_count': 1, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1158/1538-7445.am2017-4702', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S168522863', 'display_name': 'Cancer Research', 'issn_l': '0008-5472', 'issn': ['0008-5472', '1538-7445'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320273', 'host_organization_name': 'American Association for Cancer Research', 'host_organization_lineage': ['https://openalex.org/P4310320273'], 'host_organization_lineage_names': ['American Association for Cancer Research'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'display_name': 'Good health and well-being', 'score': 0.83, 'id': 'https://metadata.un.org/sdg/3'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 0, 'referenced_works': [], 'related_works': ['https://openalex.org/W4308769187', 'https://openalex.org/W4307607145', 'https://openalex.org/W3201473246', 'https://openalex.org/W3193159030', 'https://openalex.org/W3177607563', 'https://openalex.org/W3133749588', 'https://openalex.org/W3081786019', 'https://openalex.org/W3023962864', 'https://openalex.org/W2988154419', 'https://openalex.org/W2497307737'], 'abstract_inverted_index': {'Abstract': [0], 'Immune': [1], 'checkpoint': [2, 349], 'blockade': [3, 212, 250, 286, 350, 390], 'with': [4, 112, 213, 235, 248, 339], 'antibodies': [5, 214], 'aimed': [6], 'at': [7, 89], 'enhancing': [8], 'antitumor': [9], 'immunity': [10, 108, 141], 'have': [11], 'become': [12], 'an': [13, 225], 'attractive': [14], 'therapeutic': [15], 'option.': [16], 'Establishing': [17], 'immunocompetent': [18], 'and': [19, 66, 80, 93, 100, 123, 135, 157, 199, 254, 261, 330], 'clinically': [20], 'relevant': [21], 'models': [22, 52, 393], 'that': [23, 105, 302, 319, 332], 'predict': [24], 'treatment': [25, 247, 305], 'response': [26], 'is': [27], 'essential': [28], 'for': [29, 347, 405], 'the': [30, 40, 60, 67, 113, 131, 151, 279, 402], 'development': [31], 'of': [32, 43, 53, 138, 150, 196, 228, 269, 276, 284, 290, 394, 401], 'novel': [33, 44], 'immunotherapies.': [34], 'To': [35], 'gain': [36], 'better': [37], 'insights': [38], 'into': [39], 'preclinical': [41, 345, 392], 'evaluation': [42], 'immunotherapeutic': [45], 'strategies,': [46], 'we': [47, 343], 'used': [48], 'genetically': [49], 'engineered': [50], 'mouse': [51, 216, 326], 'PTEN-deficient': [54, 327, 395], 'prostate': [55, 64, 79, 82, 231, 238, 295, 328, 355, 396], 'cancer.': [56, 232], 'We': [57, 170], 'first': [58], 'analyzed': [59], 'transcriptome': [61], 'in': [62, 144, 163, 176, 205, 208, 224, 274, 325, 391], 'castration-naïve': [63, 86, 168, 237], 'tumors': [65, 165, 179, 275], 'progression': [68, 114], 'to': [69, 115, 167, 241, 252], 'castration-resistant': [70, 145, 164, 209, 230], 'disease.': [71], 'Comparative': [72], 'analyses': [73], 'were': [74, 129, 142, 161], 'performed': [75], 'between': [76], 'age-matched': [77], 'normal': [78], 'PTEN-/-': [81], 'tumor': [83, 107, 140, 220, 322], 'samples': [84], 'from': [85, 180], 'mice': [87, 234, 277, 303], 'and,': [88], '4': [90], 'weeks': [91, 95], '(castration-sensitive)': [92], '10': [94], '(castration-resistant)': [96], 'post-surgical': [97], 'castration.': [98], 'Pathway': [99], 'gene-set': [101], 'enrichment': [102], 'analysis': [103, 283], 'indicated': [104], 'abnormal': [106], 'was': [109, 187, 206, 272], 'strongly': [110, 188], 'associated': [111], 'castration': [116, 293], 'resistance.': [117], 'Chemokine': [118], 'signaling,': [119], 'B': [120], 'cell': [121, 125, 153], 'receptor': [122, 126], 'T': [124], 'signaling': [127], 'pathways': [128], 'among': [130], 'top': [132], 'dysregulated': [133], 'pathways,': [134], 'gene': [136], 'signatures': [137], 'suppressed': [139], 'enriched': [143], 'tumors.': [146, 169, 210], 'Higher': [147], 'expression': [148, 174], 'patterns': [149], 'programmed': [152], 'death': [154], 'protein': [155], '1(PD-1)': [156], 'its': [158], 'ligand': [159], '(PD-L1)': [160], 'observed': [162, 207, 273], 'compared': [166, 251], 'also': [171], 'characterized': [172], 'immune': [173, 203, 323, 348], 'profiles': [175], 'more': [177], 'aggressive': [178], 'PTEN/P53': [181], 'double': [182], 'knockout': [183], '(DKO)': [184], 'mice.': [185], 'PD-L1': [186, 217, 389], 'expressed': [189], 'cancer': [190, 239, 296, 329, 356, 397], 'cells,': [191], 'but': [192], 'a': [193, 288, 352], 'higher': [194, 267], 'presence': [195], 'PD-1+,': [197], 'CD45+': [198, 219, 270], 'F4/80+': [200], 'stromal': [201], 'infiltrating': [202, 221], 'cells': [204], 'PD-1/PD-L1': [211, 249, 285], 'against': [215], 'increased': [218], 'lymphocytes': [222], '(TILs)': [223], 'early': [226], 'model': [227, 289], 'PTEN/P53-deficient': [229, 292], 'PTEN/P53-DKO': [233], 'advanced': [236, 291], 'tended': [240], 'experienced': [242], 'longer': [243, 308], 'overall': [244], 'survival': [245, 258, 309, 312], 'after': [246], 'vehicle': [253], 'isotype': [255], 'controls,': [256], 'median': [257, 311], '23,': [259], '14': [260], '11': [262], 'days,': [263], 'respectively,': [264], 'P=0.458.': [265], 'A': [266], 'number': [268], 'TILs': [271], 'receiving': [278, 304], 'anti-PD-L1': [280, 340], 'treatment.': [281], 'Interim': [282], 'on': [287], 'resistant': [294], '(CRPC)': [297], 'has': [298], 'thus': [299], 'far': [300], 'shown': [301], 'experience': [306], 'significantly': [307], '(P=0.017,': [310], 'not': [313], 'yet': [314], 'reached).': [315], 'Our': [316], 'findings': [317], 'show': [318], 'castration-resistance': [320], 'promotes': [321], 'suppression': [324], 'suggest': [331], 'this': [333], 'phenomenon': [334], 'can': [335], 'be': [336], 'reversed': [337], 'pharmacologically': [338], 'blockade.': [341], 'Thus,': [342], 'provide': [344], 'evidence': [346], 'as': [351], 'potentially': [353], 'promising': [354], 'therapy.': [357], 'Citation': [358], 'Format:': [359], 'Marco': [360], 'A.': [361], 'De': [362], 'Velasco,': [363], 'Yurie': [364], 'Kura,': [365], 'Naomi': [366], 'Ando,': [367], 'Noriko': [368], 'Sato,': [369], 'Kazuko': [370], 'Sakai': [371], ',': [372, 386], 'Barry': [373], 'R.': [374], 'Davies,': [375], 'Koichi': [376], 'Sugimoto,': [377], 'Masahiro': [378], 'Nozawa,': [379], 'Kazuhiro': [380, 382], 'Yoshimura,': [381], 'Yoshikawa,': [383], 'Kazuto': [384], 'Nishio': [385], 'Hirotsugu': [387], 'Uemura.': [388], '[abstract].': [398], 'In:': [399], 'Proceedings': [400], 'American': [403], 'Association': [404], 'Cancer': [406, 419], 'Research': [407], 'Annual': [408], 'Meeting': [409], '2017;': [410], '2017': [411], 'Apr': [412], '1-5;': [413], 'Washington,': [414], 'DC.': [415], 'Philadelphia': [416], '(PA):': [417], 'AACR;': [418], 'Res': [420], '2017;77(13': [421], 'Suppl):Abstract': [422], 'nr': [423], '4702.': [424], 'doi:10.1158/1538-7445.AM2017-4702': [425]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2741158063', 'counts_by_year': [{'year': 2022, 'cited_by_count': 1}, {'year': 2021, 'cited_by_count': 5}, {'year': 2017, 'cited_by_count': 1}], 'updated_date': '2024-12-12T10:09:55.588044', 'created_date': '2017-08-08'}