Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W27407150', 'doi': 'https://doi.org/10.1016/b978-0-12-571149-4.50011-8', 'title': 'Biochemistry of the Src Protein-Tyrosine Kinase: Regulation by SH2 and SH3 Domains', 'display_name': 'Biochemistry of the Src Protein-Tyrosine Kinase: Regulation by SH2 and SH3 Domains', 'publication_year': 1994, 'publication_date': '1994-01-01', 'ids': {'openalex': 'https://openalex.org/W27407150', 'doi': 'https://doi.org/10.1016/b978-0-12-571149-4.50011-8', 'mag': '27407150', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/7511826'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1016/b978-0-12-571149-4.50011-8', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306463230', 'display_name': 'Elsevier eBooks', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'ebook platform'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'review', 'type_crossref': 'book-chapter', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5085173382', 'display_name': 'X. Johné Liu', 'orcid': 'https://orcid.org/0000-0003-3381-5030'}, 'institutions': [{'id': 'https://openalex.org/I1291836623', 'display_name': 'Mount Sinai Hospital', 'ror': 'https://ror.org/05deks119', 'country_code': 'CA', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1291836623', 'https://openalex.org/I4210130843']}], 'countries': ['CA'], 'is_corresponding': False, 'raw_author_name': 'XINGQUAN LIU', 'raw_affiliation_strings': ['Division of Molecular and Developmental Biology, Samuel Lunenfeld Research Institute, Mount Sinai Hospital Toronto Ontario Canada'], 'affiliations': [{'raw_affiliation_string': 'Division of Molecular and Developmental Biology, Samuel Lunenfeld Research Institute, Mount Sinai Hospital Toronto Ontario Canada', 'institution_ids': ['https://openalex.org/I1291836623']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5109102479', 'display_name': 'Tony Pawson', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I185261750', 'display_name': 'University of Toronto', 'ror': 'https://ror.org/03dbr7087', 'country_code': 'CA', 'type': 'education', 'lineage': ['https://openalex.org/I185261750']}, {'id': 'https://openalex.org/I1291836623', 'display_name': 'Mount Sinai Hospital', 'ror': 'https://ror.org/05deks119', 'country_code': 'CA', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1291836623', 'https://openalex.org/I4210130843']}, {'id': 'https://openalex.org/I210557978', 'display_name': 'Lunenfeld-Tanenbaum Research Institute', 'ror': 'https://ror.org/01s5axj25', 'country_code': 'CA', 'type': 'facility', 'lineage': ['https://openalex.org/I1291836623', 'https://openalex.org/I210557978', 'https://openalex.org/I4210130843']}], 'countries': ['CA'], 'is_corresponding': False, 'raw_author_name': 'TONY PAWSON', 'raw_affiliation_strings': ['Department of Molecular and Medical Genetics, University of Toronto, Toronto, Ontario, Canada MSG 1A8', 'Division of Molecular and Developmental Biology, Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada M5G 1X5'], 'affiliations': [{'raw_affiliation_string': 'Department of Molecular and Medical Genetics, University of Toronto, Toronto, Ontario, Canada MSG 1A8', 'institution_ids': ['https://openalex.org/I185261750']}, {'raw_affiliation_string': 'Division of Molecular and Developmental Biology, Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada M5G 1X5', 'institution_ids': ['https://openalex.org/I1291836623', 'https://openalex.org/I210557978']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 3, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 0.301, 'has_fulltext': False, 'cited_by_count': 34, 'citation_normalized_percentile': {'value': 0.561293, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 89, 'max': 90}, 'biblio': {'volume': None, 'issue': None, 'first_page': '149', 'last_page': '160'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10169', 'display_name': 'Protein Kinase Regulation and GTPase Signaling', 'score': 0.9987, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10169', 'display_name': 'Protein Kinase Regulation and GTPase Signaling', 'score': 0.9987, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T12104', 'display_name': 'Protein Tyrosine Phosphatases', 'score': 0.9933, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10044', 'display_name': 'Protein Structure and Dynamics', 'score': 0.992, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/tyrosine-protein-kinase-csk', 'display_name': 'Tyrosine-protein kinase CSK', 'score': 0.83782995}], 'concepts': [{'id': 'https://openalex.org/C108636557', 'wikidata': 'https://www.wikidata.org/wiki/Q21109354', 'display_name': 'Proto-oncogene tyrosine-protein kinase Src', 'level': 3, 'score': 0.91261184}, {'id': 'https://openalex.org/C197153747', 'wikidata': 'https://www.wikidata.org/wiki/Q24780316', 'display_name': 'SH2 domain', 'level': 4, 'score': 0.8502734}, {'id': 'https://openalex.org/C183141693', 'wikidata': 'https://www.wikidata.org/wiki/Q5005962', 'display_name': 'Tyrosine-protein kinase CSK', 'level': 5, 'score': 0.83782995}, {'id': 'https://openalex.org/C196347352', 'wikidata': 'https://www.wikidata.org/wiki/Q24771787', 'display_name': 'SH3 domain', 'level': 4, 'score': 0.79811656}, {'id': 'https://openalex.org/C42362537', 'wikidata': 'https://www.wikidata.org/wiki/Q87099740', 'display_name': 'Tyrosine kinase', 'level': 3, 'score': 0.59592414}, {'id': 'https://openalex.org/C101544691', 'wikidata': 'https://www.wikidata.org/wiki/Q420511', 'display_name': 'Receptor tyrosine kinase', 'level': 3, 'score': 0.4849565}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.4546748}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.42463917}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.40694183}, {'id': 'https://openalex.org/C11960822', 'wikidata': 'https://www.wikidata.org/wiki/Q242736', 'display_name': 'Phosphorylation', 'level': 2, 'score': 0.4065097}, {'id': 'https://openalex.org/C95444343', 'wikidata': 'https://www.wikidata.org/wiki/Q7141', 'display_name': 'Cell biology', 'level': 1, 'score': 0.40386736}, {'id': 'https://openalex.org/C62478195', 'wikidata': 'https://www.wikidata.org/wiki/Q828130', 'display_name': 'Signal transduction', 'level': 2, 'score': 0.33618698}], 'mesh': [{'descriptor_ui': 'D011505', 'descriptor_name': 'Protein-Tyrosine Kinases', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D016392', 'descriptor_name': 'Proto-Oncogene Proteins pp60(c-src)', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D000595', 'descriptor_name': 'Amino Acid Sequence', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001665', 'descriptor_name': 'Binding Sites', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002471', 'descriptor_name': 'Cell Transformation, Neoplastic', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008969', 'descriptor_name': 'Molecular Sequence Data', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D010766', 'descriptor_name': 'Phosphorylation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011505', 'descriptor_name': 'Protein-Tyrosine Kinases', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': False}, {'descriptor_ui': 'D011505', 'descriptor_name': 'Protein-Tyrosine Kinases', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D016392', 'descriptor_name': 'Proto-Oncogene Proteins pp60(c-src)', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': False}, {'descriptor_ui': 'D016392', 'descriptor_name': 'Proto-Oncogene Proteins pp60(c-src)', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013329', 'descriptor_name': 'Structure-Activity Relationship', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013379', 'descriptor_name': 'Substrate Specificity', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1016/b978-0-12-571149-4.50011-8', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306463230', 'display_name': 'Elsevier eBooks', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'ebook platform'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/7511826', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 67, 'referenced_works': ['https://openalex.org/W115395656', 'https://openalex.org/W1492950839', 'https://openalex.org/W1506509855', 'https://openalex.org/W1549736588', 'https://openalex.org/W1565159606', 'https://openalex.org/W1583862968', 'https://openalex.org/W1594494223', 'https://openalex.org/W1655336816', 'https://openalex.org/W1701189440', 'https://openalex.org/W1749710960', 'https://openalex.org/W1854914172', 'https://openalex.org/W1903523888', 'https://openalex.org/W1909995282', 'https://openalex.org/W1942911026', 'https://openalex.org/W1943448711', 'https://openalex.org/W1966520635', 'https://openalex.org/W1968472053', 'https://openalex.org/W1969071487', 'https://openalex.org/W1973365703', 'https://openalex.org/W1974517994', 'https://openalex.org/W1974814389', 'https://openalex.org/W1980554628', 'https://openalex.org/W1981810445', 'https://openalex.org/W1987981273', 'https://openalex.org/W2000170431', 'https://openalex.org/W2000939282', 'https://openalex.org/W2003044215', 'https://openalex.org/W2005529016', 'https://openalex.org/W2009715603', 'https://openalex.org/W2014397920', 'https://openalex.org/W2016553217', 'https://openalex.org/W2020537787', 'https://openalex.org/W2025018535', 'https://openalex.org/W2029819915', 'https://openalex.org/W2030577752', 'https://openalex.org/W2034152669', 'https://openalex.org/W2038816853', 'https://openalex.org/W2039610291', 'https://openalex.org/W2042824379', 'https://openalex.org/W2044661739', 'https://openalex.org/W2049355608', 'https://openalex.org/W2050925121', 'https://openalex.org/W2051942264', 'https://openalex.org/W2059106195', 'https://openalex.org/W2070623976', 'https://openalex.org/W2085154580', 'https://openalex.org/W2087656195', 'https://openalex.org/W2088638041', 'https://openalex.org/W2089375674', 'https://openalex.org/W2090695896', 'https://openalex.org/W2093913186', 'https://openalex.org/W2100974630', 'https://openalex.org/W2108107129', 'https://openalex.org/W2112093320', 'https://openalex.org/W2124977952', 'https://openalex.org/W2146644912', 'https://openalex.org/W2157189324', 'https://openalex.org/W2157342751', 'https://openalex.org/W2159575819', 'https://openalex.org/W2162075350', 'https://openalex.org/W2305225747', 'https://openalex.org/W2412533640', 'https://openalex.org/W2415639145', 'https://openalex.org/W2439069116', 'https://openalex.org/W267749267', 'https://openalex.org/W5386695', 'https://openalex.org/W92507475'], 'related_works': ['https://openalex.org/W3144869401', 'https://openalex.org/W27407150', 'https://openalex.org/W2473186428', 'https://openalex.org/W2158481045', 'https://openalex.org/W2081048050', 'https://openalex.org/W2054466658', 'https://openalex.org/W2032116260', 'https://openalex.org/W1999996757', 'https://openalex.org/W1981772486', 'https://openalex.org/W113286307'], 'abstract_inverted_index': None, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W27407150', 'counts_by_year': [{'year': 2018, 'cited_by_count': 2}, {'year': 2015, 'cited_by_count': 1}, {'year': 2013, 'cited_by_count': 1}, {'year': 2012, 'cited_by_count': 2}], 'updated_date': '2024-12-16T04:16:00.134100', 'created_date': '2016-06-24'}