Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2725954495', 'doi': 'https://doi.org/10.18632/oncotarget.18830', 'title': 'Overexpression of CHD1L is associated with poor survival and aggressive tumor biology in esophageal carcinoma', 'display_name': 'Overexpression of CHD1L is associated with poor survival and aggressive tumor biology in esophageal carcinoma', 'publication_year': 2017, 'publication_date': '2017-06-29', 'ids': {'openalex': 'https://openalex.org/W2725954495', 'doi': 'https://doi.org/10.18632/oncotarget.18830', 'mag': '2725954495', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/29088777', 'pmcid': 'https://www.ncbi.nlm.nih.gov/pmc/articles/5650332'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.18632/oncotarget.18830', 'pdf_url': 'http://www.oncotarget.com/index.php?journal=oncotarget&page=article&op=download&path%5B%5D=18830&path%5B%5D=66446', 'source': {'id': 'https://openalex.org/S126644158', 'display_name': 'Oncotarget', 'issn_l': '1949-2553', 'issn': ['1949-2553'], 'is_oa': True, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310316297', 'host_organization_name': 'Impact Journals LLC', 'host_organization_lineage': ['https://openalex.org/P4310316297'], 'host_organization_lineage_names': ['Impact Journals LLC'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'gold', 'oa_url': 'http://www.oncotarget.com/index.php?journal=oncotarget&page=article&op=download&path%5B%5D=18830&path%5B%5D=66446', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5054709387', 'display_name': 'Zehan Liu', 'orcid': 'https://orcid.org/0000-0003-1059-6445'}, 'institutions': [{'id': 'https://openalex.org/I5740404', 'display_name': 'Tianjin Medical University', 'ror': 'https://ror.org/02mh8wx89', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I5740404']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Ze-Han Liu', 'raw_affiliation_strings': ['Nankai Clinical College, Tianjin Medical University, Tianjin, P.R. China'], 'affiliations': [{'raw_affiliation_string': 'Nankai Clinical College, Tianjin Medical University, Tianjin, P.R. China', 'institution_ids': ['https://openalex.org/I5740404']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5100360246', 'display_name': 'Qi Zhang', 'orcid': 'https://orcid.org/0000-0001-9916-8919'}, 'institutions': [{'id': 'https://openalex.org/I5740404', 'display_name': 'Tianjin Medical University', 'ror': 'https://ror.org/02mh8wx89', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I5740404']}, {'id': 'https://openalex.org/I4210093484', 'display_name': 'Tianjin Nankai Hospital', 'ror': 'https://ror.org/00hq79z10', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210093484']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Qi Zhang', 'raw_affiliation_strings': ['Institute of Integrative Medicine Therapy for Acute Abdominal Diseases of Tianjin, Nankai Hospital, Tianjin, P. R. China', 'Laboratory of Immunology and Inflammation, Department of Immunology, Key Laboratory of Immune Microenvironment and Diseases of Educational Ministry of China, Basic Medical College, Tianjin Medical University, Tianjin, P.R. China'], 'affiliations': [{'raw_affiliation_string': 'Laboratory of Immunology and Inflammation, Department of Immunology, Key Laboratory of Immune Microenvironment and Diseases of Educational Ministry of China, Basic Medical College, Tianjin Medical University, Tianjin, P.R. China', 'institution_ids': ['https://openalex.org/I5740404']}, {'raw_affiliation_string': 'Institute of Integrative Medicine Therapy for Acute Abdominal Diseases of Tianjin, Nankai Hospital, Tianjin, P. R. China', 'institution_ids': ['https://openalex.org/I4210093484']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5015775730', 'display_name': 'Yijie Ding', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I5740404', 'display_name': 'Tianjin Medical University', 'ror': 'https://ror.org/02mh8wx89', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I5740404']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Yi-Jie Ding', 'raw_affiliation_strings': ['First Central Clinical College, Tianjin Medical University, Tianjin, P.R. China'], 'affiliations': [{'raw_affiliation_string': 'First Central Clinical College, Tianjin Medical University, Tianjin, P.R. China', 'institution_ids': ['https://openalex.org/I5740404']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5101535056', 'display_name': 'Yinghui Ren', 'orcid': 'https://orcid.org/0009-0005-0533-1268'}, 'institutions': [{'id': 'https://openalex.org/I5740404', 'display_name': 'Tianjin Medical University', 'ror': 'https://ror.org/02mh8wx89', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I5740404']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Ying-Hui Ren', 'raw_affiliation_strings': ['Laboratory of Immunology and Inflammation, Department of Immunology, Key Laboratory of Immune Microenvironment and Diseases of Educational Ministry of China, Basic Medical College, Tianjin Medical University, Tianjin, P.R. China'], 'affiliations': [{'raw_affiliation_string': 'Laboratory of Immunology and Inflammation, Department of Immunology, Key Laboratory of Immune Microenvironment and Diseases of Educational Ministry of China, Basic Medical College, Tianjin Medical University, Tianjin, P.R. China', 'institution_ids': ['https://openalex.org/I5740404']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5012037038', 'display_name': 'Huipeng Yang', 'orcid': 'https://orcid.org/0000-0002-6936-9928'}, 'institutions': [{'id': 'https://openalex.org/I5740404', 'display_name': 'Tianjin Medical University', 'ror': 'https://ror.org/02mh8wx89', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I5740404']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Hui-Peng Yang', 'raw_affiliation_strings': ['Laboratory of Immunology and Inflammation, Department of Immunology, Key Laboratory of Immune Microenvironment and Diseases of Educational Ministry of China, Basic Medical College, Tianjin Medical University, Tianjin, P.R. China'], 'affiliations': [{'raw_affiliation_string': 'Laboratory of Immunology and Inflammation, Department of Immunology, Key Laboratory of Immune Microenvironment and Diseases of Educational Ministry of China, Basic Medical College, Tianjin Medical University, Tianjin, P.R. China', 'institution_ids': ['https://openalex.org/I5740404']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5048502872', 'display_name': 'Qing Xi', 'orcid': 'https://orcid.org/0000-0001-8011-5219'}, 'institutions': [{'id': 'https://openalex.org/I5740404', 'display_name': 'Tianjin Medical University', 'ror': 'https://ror.org/02mh8wx89', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I5740404']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Qing Xi', 'raw_affiliation_strings': ['Laboratory of Immunology and Inflammation, Department of Immunology, Key Laboratory of Immune Microenvironment and Diseases of Educational Ministry of China, Basic Medical College, Tianjin Medical University, Tianjin, P.R. China'], 'affiliations': [{'raw_affiliation_string': 'Laboratory of Immunology and Inflammation, Department of Immunology, Key Laboratory of Immune Microenvironment and Diseases of Educational Ministry of China, Basic Medical College, Tianjin Medical University, Tianjin, P.R. China', 'institution_ids': ['https://openalex.org/I5740404']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5011105218', 'display_name': 'Yingnan Cheng', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I5740404', 'display_name': 'Tianjin Medical University', 'ror': 'https://ror.org/02mh8wx89', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I5740404']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Ying-Nan Cheng', 'raw_affiliation_strings': ['Laboratory of Immunology and Inflammation, Department of Immunology, Key Laboratory of Immune Microenvironment and Diseases of Educational Ministry of China, Basic Medical College, Tianjin Medical University, Tianjin, P.R. China'], 'affiliations': [{'raw_affiliation_string': 'Laboratory of Immunology and Inflammation, Department of Immunology, Key Laboratory of Immune Microenvironment and Diseases of Educational Ministry of China, Basic Medical College, Tianjin Medical University, Tianjin, P.R. China', 'institution_ids': ['https://openalex.org/I5740404']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5013752934', 'display_name': 'Guolin Miao', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I5740404', 'display_name': 'Tianjin Medical University', 'ror': 'https://ror.org/02mh8wx89', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I5740404']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Guo-Lin Miao', 'raw_affiliation_strings': ['Laboratory of Immunology and Inflammation, Department of Immunology, Key Laboratory of Immune Microenvironment and Diseases of Educational Ministry of China, Basic Medical College, Tianjin Medical University, Tianjin, P.R. China'], 'affiliations': [{'raw_affiliation_string': 'Laboratory of Immunology and Inflammation, Department of Immunology, Key Laboratory of Immune Microenvironment and Diseases of Educational Ministry of China, Basic Medical College, Tianjin Medical University, Tianjin, P.R. China', 'institution_ids': ['https://openalex.org/I5740404']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5004761284', 'display_name': 'Hongkun Liu', 'orcid': 'https://orcid.org/0000-0002-3329-8902'}, 'institutions': [{'id': 'https://openalex.org/I5740404', 'display_name': 'Tianjin Medical University', 'ror': 'https://ror.org/02mh8wx89', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I5740404']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Hong-Kun Liu', 'raw_affiliation_strings': ['Laboratory of Immunology and Inflammation, Department of Immunology, Key Laboratory of Immune Microenvironment and Diseases of Educational Ministry of China, Basic Medical College, Tianjin Medical University, Tianjin, P.R. China'], 'affiliations': [{'raw_affiliation_string': 'Laboratory of Immunology and Inflammation, Department of Immunology, Key Laboratory of Immune Microenvironment and Diseases of Educational Ministry of China, Basic Medical College, Tianjin Medical University, Tianjin, P.R. China', 'institution_ids': ['https://openalex.org/I5740404']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5100412349', 'display_name': 'Caixia Li', 'orcid': 'https://orcid.org/0000-0003-3079-4158'}, 'institutions': [{'id': 'https://openalex.org/I4210093484', 'display_name': 'Tianjin Nankai Hospital', 'ror': 'https://ror.org/00hq79z10', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210093484']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Cai-Xia Li', 'raw_affiliation_strings': ['Institute of Integrative Medicine Therapy for Acute Abdominal Diseases of Tianjin, Nankai Hospital, Tianjin, P. R. China'], 'affiliations': [{'raw_affiliation_string': 'Institute of Integrative Medicine Therapy for Acute Abdominal Diseases of Tianjin, Nankai Hospital, Tianjin, P. R. China', 'institution_ids': ['https://openalex.org/I4210093484']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5103759011', 'display_name': 'Wenqiang Yan', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210093484', 'display_name': 'Tianjin Nankai Hospital', 'ror': 'https://ror.org/00hq79z10', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210093484']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Wen-Qiang Yan', 'raw_affiliation_strings': ['Department of Thoracic Surgery, Nankai Hospital, Nankai District, Tianjin, P. R. China'], 'affiliations': [{'raw_affiliation_string': 'Department of Thoracic Surgery, Nankai Hospital, Nankai District, Tianjin, P. R. China', 'institution_ids': ['https://openalex.org/I4210093484']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5083960636', 'display_name': 'Yan Li', 'orcid': 'https://orcid.org/0009-0002-0817-0525'}, 'institutions': [{'id': 'https://openalex.org/I5740404', 'display_name': 'Tianjin Medical University', 'ror': 'https://ror.org/02mh8wx89', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I5740404']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Yan Li', 'raw_affiliation_strings': ['Laboratory of Immunology and Inflammation, Department of Immunology, Key Laboratory of Immune Microenvironment and Diseases of Educational Ministry of China, Basic Medical College, Tianjin Medical University, Tianjin, P.R. China'], 'affiliations': [{'raw_affiliation_string': 'Laboratory of Immunology and Inflammation, Department of Immunology, Key Laboratory of Immune Microenvironment and Diseases of Educational Ministry of China, Basic Medical College, Tianjin Medical University, Tianjin, P.R. China', 'institution_ids': ['https://openalex.org/I5740404']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5102304493', 'display_name': 'Zhenyi Xue', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I5740404', 'display_name': 'Tianjin Medical University', 'ror': 'https://ror.org/02mh8wx89', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I5740404']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Zhenyi Xue', 'raw_affiliation_strings': ['Laboratory of Immunology and Inflammation, Department of Immunology, Key Laboratory of Immune Microenvironment and Diseases of Educational Ministry of China, Basic Medical College, Tianjin Medical University, Tianjin, P.R. China'], 'affiliations': [{'raw_affiliation_string': 'Laboratory of Immunology and Inflammation, Department of Immunology, Key Laboratory of Immune Microenvironment and Diseases of Educational Ministry of China, Basic Medical College, Tianjin Medical University, Tianjin, P.R. China', 'institution_ids': ['https://openalex.org/I5740404']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5101742243', 'display_name': 'Qian Zhang', 'orcid': 'https://orcid.org/0000-0002-8421-2419'}, 'institutions': [{'id': 'https://openalex.org/I5740404', 'display_name': 'Tianjin Medical University', 'ror': 'https://ror.org/02mh8wx89', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I5740404']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Lijuan Zhang', 'raw_affiliation_strings': ['Laboratory of Immunology and Inflammation, Department of Immunology, Key Laboratory of Immune Microenvironment and Diseases of Educational Ministry of China, Basic Medical College, Tianjin Medical University, Tianjin, P.R. China'], 'affiliations': [{'raw_affiliation_string': 'Laboratory of Immunology and Inflammation, Department of Immunology, Key Laboratory of Immune Microenvironment and Diseases of Educational Ministry of China, Basic Medical College, Tianjin Medical University, Tianjin, P.R. China', 'institution_ids': ['https://openalex.org/I5740404']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5038081962', 'display_name': 'Xinye Li', 'orcid': 'https://orcid.org/0000-0001-8131-4981'}, 'institutions': [{'id': 'https://openalex.org/I2802534033', 'display_name': 'Tianjin Medical University General Hospital', 'ror': 'https://ror.org/003sav965', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2802534033']}, {'id': 'https://openalex.org/I5740404', 'display_name': 'Tianjin Medical University', 'ror': 'https://ror.org/02mh8wx89', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I5740404']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Xin-Ye Li', 'raw_affiliation_strings': ['General Hospital, Tianjin Medical University, Tianjin, P.R. China'], 'affiliations': [{'raw_affiliation_string': 'General Hospital, Tianjin Medical University, Tianjin, P.R. China', 'institution_ids': ['https://openalex.org/I2802534033', 'https://openalex.org/I5740404']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5103140209', 'display_name': 'Chenglong Zhao', 'orcid': 'https://orcid.org/0000-0003-2831-1671'}, 'institutions': [{'id': 'https://openalex.org/I2802534033', 'display_name': 'Tianjin Medical University General Hospital', 'ror': 'https://ror.org/003sav965', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2802534033']}, {'id': 'https://openalex.org/I5740404', 'display_name': 'Tianjin Medical University', 'ror': 'https://ror.org/02mh8wx89', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I5740404']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Chen-Long Zhao', 'raw_affiliation_strings': ['General Hospital, Tianjin Medical University, Tianjin, P.R. China'], 'affiliations': [{'raw_affiliation_string': 'General Hospital, Tianjin Medical University, Tianjin, P.R. China', 'institution_ids': ['https://openalex.org/I2802534033', 'https://openalex.org/I5740404']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5072433198', 'display_name': 'Yurong Da', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I5740404', 'display_name': 'Tianjin Medical University', 'ror': 'https://ror.org/02mh8wx89', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I5740404']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Yurong Da', 'raw_affiliation_strings': ['Laboratory of Immunology and Inflammation, Department of Immunology, Key Laboratory of Immune Microenvironment and Diseases of Educational Ministry of China, Basic Medical College, Tianjin Medical University, Tianjin, P.R. China'], 'affiliations': [{'raw_affiliation_string': 'Laboratory of Immunology and Inflammation, Department of Immunology, Key Laboratory of Immune Microenvironment and Diseases of Educational Ministry of China, Basic Medical College, Tianjin Medical University, Tianjin, P.R. China', 'institution_ids': ['https://openalex.org/I5740404']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5104110244', 'display_name': 'Xianzhong Wu', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210093484', 'display_name': 'Tianjin Nankai Hospital', 'ror': 'https://ror.org/00hq79z10', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210093484']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Xian-Zhong Wu', 'raw_affiliation_strings': ['Institute of Integrative Medicine Therapy for Acute Abdominal Diseases of Tianjin, Nankai Hospital, Tianjin, P. R. China'], 'affiliations': [{'raw_affiliation_string': 'Institute of Integrative Medicine Therapy for Acute Abdominal Diseases of Tianjin, Nankai Hospital, Tianjin, P. R. China', 'institution_ids': ['https://openalex.org/I4210093484']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5010117153', 'display_name': 'Junqiang Chen', 'orcid': 'https://orcid.org/0000-0003-1484-9382'}, 'institutions': [{'id': 'https://openalex.org/I4210148548', 'display_name': 'Fujian Provincial Cancer Hospital', 'ror': 'https://ror.org/058ms9w43', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210148548']}, {'id': 'https://openalex.org/I129708740', 'display_name': 'Fujian Medical University', 'ror': 'https://ror.org/050s6ns64', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I129708740']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Jun-Qiang Chen', 'raw_affiliation_strings': ['Department of Radiotherapy, Fujian Provincial Tumor Hospital, Affiliated Tumor Hospital of Fujian Medical University, Fuzhou, P.R. China'], 'affiliations': [{'raw_affiliation_string': 'Department of Radiotherapy, Fujian Provincial Tumor Hospital, Affiliated Tumor Hospital of Fujian Medical University, Fuzhou, P.R. China', 'institution_ids': ['https://openalex.org/I4210148548', 'https://openalex.org/I129708740']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5007708850', 'display_name': 'Rongxin Zhang', 'orcid': 'https://orcid.org/0000-0002-4083-374X'}, 'institutions': [{'id': 'https://openalex.org/I190242452', 'display_name': 'Guangdong Pharmaceutical University', 'ror': 'https://ror.org/02vg7mz57', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I190242452']}, {'id': 'https://openalex.org/I5740404', 'display_name': 'Tianjin Medical University', 'ror': 'https://ror.org/02mh8wx89', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I5740404']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Rongxin Zhang', 'raw_affiliation_strings': ['Laboratory of Immunology and Inflammation, Department of Immunology, Key Laboratory of Immune Microenvironment and Diseases of Educational Ministry of China, Basic Medical College, Tianjin Medical University, Tianjin, P.R. China', 'Laboratory of Immunology and Inflammation, Guangdong Pharmaceutical University, Guangzhou, P.R. China'], 'affiliations': [{'raw_affiliation_string': 'Laboratory of Immunology and Inflammation, Guangdong Pharmaceutical University, Guangzhou, P.R. China', 'institution_ids': ['https://openalex.org/I190242452']}, {'raw_affiliation_string': 'Laboratory of Immunology and Inflammation, Department of Immunology, Key Laboratory of Immune Microenvironment and Diseases of Educational Ministry of China, Basic Medical College, Tianjin Medical University, Tianjin, P.R. China', 'institution_ids': ['https://openalex.org/I5740404']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5052059747', 'display_name': 'Zhigang Li', 'orcid': 'https://orcid.org/0000-0001-5086-5334'}, 'institutions': [{'id': 'https://openalex.org/I4210158567', 'display_name': 'Hainan Medical College Hospital', 'ror': 'https://ror.org/04jg69j33', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210158567']}, {'id': 'https://openalex.org/I2802534033', 'display_name': 'Tianjin Medical University General Hospital', 'ror': 'https://ror.org/003sav965', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2802534033']}, {'id': 'https://openalex.org/I5740404', 'display_name': 'Tianjin Medical University', 'ror': 'https://ror.org/02mh8wx89', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I5740404']}, {'id': 'https://openalex.org/I4210093484', 'display_name': 'Tianjin Nankai Hospital', 'ror': 'https://ror.org/00hq79z10', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210093484']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Zhi-Gang Li', 'raw_affiliation_strings': ['General Hospital, Tianjin Medical University, Tianjin, P.R. China', 'Hainan Cancer Hospital, Affiliated Cancer Hospital of Hainan Medical College, Haikou City, P.R. China', 'Institute of Integrative Medicine Therapy for Acute Abdominal Diseases of Tianjin, Nankai Hospital, Tianjin, P. R. China'], 'affiliations': [{'raw_affiliation_string': 'Hainan Cancer Hospital, Affiliated Cancer Hospital of Hainan Medical College, Haikou City, P.R. China', 'institution_ids': ['https://openalex.org/I4210158567']}, {'raw_affiliation_string': 'General Hospital, Tianjin Medical University, Tianjin, P.R. China', 'institution_ids': ['https://openalex.org/I2802534033', 'https://openalex.org/I5740404']}, {'raw_affiliation_string': 'Institute of Integrative Medicine Therapy for Acute Abdominal Diseases of Tianjin, Nankai Hospital, Tianjin, P. R. China', 'institution_ids': ['https://openalex.org/I4210093484']}]}], 'countries_distinct_count': 1, 'institutions_distinct_count': 7, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 0.538, 'has_fulltext': True, 'fulltext_origin': 'pdf', 'cited_by_count': 9, 'citation_normalized_percentile': {'value': 0.729964, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 85, 'max': 86}, 'biblio': {'volume': '8', 'issue': '43', 'first_page': '74178', 'last_page': '74187'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10158', 'display_name': 'Cancer Immunotherapy', 'score': 0.9993, 'subfield': {'id': 'https://openalex.org/subfields/2730', 'display_name': 'Oncology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10158', 'display_name': 'Cancer Immunotherapy', 'score': 0.9993, 'subfield': {'id': 'https://openalex.org/subfields/2730', 'display_name': 'Oncology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T11482', 'display_name': 'RNA Methylation and Modification in Gene Expression', 'score': 0.999, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T13157', 'display_name': 'Protein Arginine Methylation in Mammals', 'score': 0.9986, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/tumor-microenvironment', 'display_name': 'Tumor Microenvironment', 'score': 0.526807}, {'id': 'https://openalex.org/keywords/cancer-immunoediting', 'display_name': 'Cancer Immunoediting', 'score': 0.524211}, {'id': 'https://openalex.org/keywords/christian-ministry', 'display_name': 'Christian ministry', 'score': 0.5113308}, {'id': 'https://openalex.org/keywords/cancer-progression', 'display_name': 'Cancer Progression', 'score': 0.505398}, {'id': 'https://openalex.org/keywords/zhàng', 'display_name': 'Zhàng', 'score': 0.41967073}], 'concepts': [{'id': 'https://openalex.org/C191935318', 'wikidata': 'https://www.wikidata.org/wiki/Q148', 'display_name': 'China', 'level': 2, 'score': 0.69297785}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.6546792}, {'id': 'https://openalex.org/C521751864', 'wikidata': 'https://www.wikidata.org/wiki/Q1729207', 'display_name': 'Christian ministry', 'level': 2, 'score': 0.5113308}, {'id': 'https://openalex.org/C2777045944', 'wikidata': 'https://www.wikidata.org/wiki/Q12170198', 'display_name': 'Zhàng', 'level': 3, 'score': 0.41967073}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.40822032}, {'id': 'https://openalex.org/C143998085', 'wikidata': 'https://www.wikidata.org/wiki/Q162555', 'display_name': 'Oncology', 'level': 1, 'score': 0.35834497}, {'id': 'https://openalex.org/C512399662', 'wikidata': 'https://www.wikidata.org/wiki/Q3505712', 'display_name': 'Family medicine', 'level': 1, 'score': 0.3421037}, {'id': 'https://openalex.org/C556039675', 'wikidata': 'https://www.wikidata.org/wiki/Q771035', 'display_name': 'Traditional medicine', 'level': 1, 'score': 0.3350542}, {'id': 'https://openalex.org/C27206212', 'wikidata': 'https://www.wikidata.org/wiki/Q34178', 'display_name': 'Theology', 'level': 1, 'score': 0.13342506}, {'id': 'https://openalex.org/C95457728', 'wikidata': 'https://www.wikidata.org/wiki/Q309', 'display_name': 'History', 'level': 0, 'score': 0.12941393}, {'id': 'https://openalex.org/C138885662', 'wikidata': 'https://www.wikidata.org/wiki/Q5891', 'display_name': 'Philosophy', 'level': 0, 'score': 0.0}, {'id': 'https://openalex.org/C166957645', 'wikidata': 'https://www.wikidata.org/wiki/Q23498', 'display_name': 'Archaeology', 'level': 1, 'score': 0.0}], 'mesh': [], 'locations_count': 4, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.18632/oncotarget.18830', 'pdf_url': 'http://www.oncotarget.com/index.php?journal=oncotarget&page=article&op=download&path%5B%5D=18830&path%5B%5D=66446', 'source': {'id': 'https://openalex.org/S126644158', 'display_name': 'Oncotarget', 'issn_l': '1949-2553', 'issn': ['1949-2553'], 'is_oa': True, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310316297', 'host_organization_name': 'Impact Journals LLC', 'host_organization_lineage': ['https://openalex.org/P4310316297'], 'host_organization_lineage_names': ['Impact Journals LLC'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://europepmc.org/articles/pmc5650332', 'pdf_url': 'https://europepmc.org/articles/pmc5650332?pdf=render', 'source': {'id': 'https://openalex.org/S4306400806', 'display_name': 'Europe PMC (PubMed Central)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1303153112', 'host_organization_name': 'European Bioinformatics Institute', 'host_organization_lineage': ['https://openalex.org/I1303153112'], 'host_organization_lineage_names': ['European Bioinformatics Institute'], 'type': 'repository'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5650332', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/29088777', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.18632/oncotarget.18830', 'pdf_url': 'http://www.oncotarget.com/index.php?journal=oncotarget&page=article&op=download&path%5B%5D=18830&path%5B%5D=66446', 'source': {'id': 'https://openalex.org/S126644158', 'display_name': 'Oncotarget', 'issn_l': '1949-2553', 'issn': ['1949-2553'], 'is_oa': True, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310316297', 'host_organization_name': 'Impact Journals LLC', 'host_organization_lineage': ['https://openalex.org/P4310316297'], 'host_organization_lineage_names': ['Impact Journals LLC'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [{'display_name': 'No poverty', 'score': 0.59, 'id': 'https://metadata.un.org/sdg/1'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 31, 'referenced_works': ['https://openalex.org/W1520425169', 'https://openalex.org/W1992146030', 'https://openalex.org/W2000199388', 'https://openalex.org/W2010158116', 'https://openalex.org/W2016603998', 'https://openalex.org/W2029592915', 'https://openalex.org/W2054606083', 'https://openalex.org/W2058258230', 'https://openalex.org/W2066885008', 'https://openalex.org/W2068061076', 'https://openalex.org/W2074478596', 'https://openalex.org/W2092668333', 'https://openalex.org/W2102482497', 'https://openalex.org/W2106326014', 'https://openalex.org/W2113253176', 'https://openalex.org/W2115675920', 'https://openalex.org/W2117910394', 'https://openalex.org/W2120816732', 'https://openalex.org/W2129138183', 'https://openalex.org/W2139028366', 'https://openalex.org/W2139903560', 'https://openalex.org/W2145699080', 'https://openalex.org/W2146678830', 'https://openalex.org/W2165256123', 'https://openalex.org/W2170552969', 'https://openalex.org/W2174026431', 'https://openalex.org/W2257796989', 'https://openalex.org/W2260536780', 'https://openalex.org/W2337619586', 'https://openalex.org/W2555053325', 'https://openalex.org/W2563470051'], 'related_works': ['https://openalex.org/W2517160981', 'https://openalex.org/W2513786983', 'https://openalex.org/W2510877670', 'https://openalex.org/W2510495077', 'https://openalex.org/W2507155845', 'https://openalex.org/W2347978077', 'https://openalex.org/W2286747645', 'https://openalex.org/W2153749842', 'https://openalex.org/W2020567493', 'https://openalex.org/W2005271262'], 'abstract_inverted_index': {'//': [0], 'Ze-Han': [1], 'Liu': [2, 38], '1,': [3], '*': [4, 10, 15, 227], ',': [5, 11, 16, 20, 24, 28, 32, 36, 40, 44, 48, 52, 56, 60, 64, 68, 72, 76, 80, 246], 'Qi': [6], 'Zhang': [7, 58, 82], '2,': [8], '3,': [9], 'Yi-Jie': [12], 'Ding': [13], '4,': [14], 'Ying-Hui': [17], 'Ren': [18], '3': [19, 23, 27, 31, 35, 39, 51, 55, 59, 71, 84, 119], 'Hui-Peng': [21], 'Yang': [22], 'Qing': [25], 'Xi': [26], 'Ying-Nan': [29], 'Cheng': [30], 'Guo-Lin': [33], 'Miao': [34], 'Hong-Kun': [37], 'Cai-Xia': [41], 'Li': [42, 50, 62, 87], '2': [43, 75, 90, 101], 'Wen-Qiang': [45], 'Yan': [46, 49], '5': [47, 160], 'Zhenyi': [53], 'Xue': [54], 'Lijuan': [57], 'Xin-Ye': [61], '6': [63, 67, 173], 'Chen-Long': [65], 'Zhao': [66], 'Yurong': [69], 'Da': [70], 'Xian-Zhong': [73], 'Wu': [74], 'Jun-Qiang': [77, 238], 'Chen': [78], '7': [79, 182], 'Rongxin': [81, 242], '8,': [83], 'and': [85, 123, 133, 204, 299, 316, 336, 361, 365, 400, 429, 452], 'Zhi-Gang': [86, 248], '9,': [88], '6,': [89], '1': [91], 'Nankai': [92, 113, 165, 167], 'Clinical': [93, 152], 'College,': [94, 142, 153, 222], 'Tianjin': [95, 143, 154, 176], 'Medical': [96, 141, 144, 155, 177, 195, 221], 'University,': [97, 145, 156, 178, 196, 208], 'Tianjin,': [98, 112, 115, 146, 157, 169, 179], 'P.R.': [99, 147, 158, 180, 198, 210, 225], 'China': [100, 118, 148, 159, 172, 181, 199, 211, 226], 'Institute': [102], 'of': [103, 111, 121, 126, 130, 135, 138, 162, 184, 193, 202, 219, 310, 330, 345, 369, 407, 416, 423, 440, 445], 'Integrative': [104], 'Medicine': [105], 'Therapy': [106], 'for': [107], 'Acute': [108], 'Abdominal': [109], 'Diseases': [110, 134], 'Hospital,': [114, 166, 175, 189, 215], 'P.': [116, 170], 'R.': [117, 171], 'Laboratory': [120, 129, 201], 'Immunology': [122, 203], 'Inflammation,': [124, 205], 'Department': [125, 161, 183], 'Immunology,': [127], 'Key': [128], 'Immune': [131], 'Microenvironment': [132], 'Educational': [136], 'Ministry': [137], 'China,': [139], 'Basic': [140], '4': [149], 'First': [150], 'Central': [151], 'Thoracic': [163], 'Surgery,': [164], 'District,': [168], 'General': [174], 'Radiotherapy,': [185], 'Fujian': [186, 194], 'Provincial': [187], 'Tumor': [188, 191], 'Affiliated': [190, 216], 'Hospital': [192, 218], 'Fuzhou,': [197], '8': [200], 'Guangdong': [206], 'Pharmaceutical': [207], 'Guangzhou,': [209], '9': [212], 'Hainan': [213, 220], 'Cancer': [214, 217], 'Haikou': [223], 'City,': [224], 'These': [228], 'authors': [229], 'have': [230], 'contributed': [231], 'equally': [232], 'to': [233, 326, 393, 470], 'this': [234], 'work': [235], 'Correspondence': [236], 'to:': [237], 'Chen,': [239], 'email:': [240, 244, 250], '[email protected]': [241], 'Zhang,': [243], '[email protected]': [245], '[email protected]': [247], 'Li,': [249], '[email protected]': [251], 'Keywords:': [252], 'esophageal': [253], 'carcinoma,': [254], 'CHD1L': [255, 311, 331, 346, 359, 370, 378, 388, 417, 434, 446, 462], 'protein,': [256], 'apoptosis,': [257], 'migration,': [258], 'prognosis': [259, 422], 'Received:': [260], 'March': [261], '21,': [262], '2017 ': [263, 267], 'Accepted:': [264], 'June': [265, 269], '04,': [266], 'Published:': [268], '29,': [270], '2017': [271], 'ABSTRACT': [272], 'Esophageal': [273], 'carcinoma': [274], '(EC)': [275], 'is': [276, 291, 301, 320, 463], 'a': [277, 292, 464, 473], 'malignancy': [278], 'with': [279, 467], 'high': [280, 414], 'metastatic': [281], 'potential.': [282], 'Chromosomal': [283], 'helicase/ATPase': [284], 'DNA': [285], 'binding': [286], 'protein': [287, 312], '1-like': [288], '(CHD1L)': [289], 'gene': [290], 'newly': [293], 'identified': [294], 'oncogene': [295, 466], 'located': [296], 'at': [297], 'Chr1q21,': [298], 'it': [300], 'amplified': [302], 'in': [303, 314, 333, 340, 351, 381, 420, 447, 477], 'many': [304], 'solid': [305], 'tumors.': [306], 'However,': [307], 'the': [308, 328, 366, 468], 'status': [309], 'expression': [313, 332, 344, 360, 389, 415], 'EC': [315, 335, 341, 382, 424, 448, 478], 'its': [317, 337], 'clinical': [318, 362, 395], 'significance': [319, 329], 'uncertain.': [321], 'This': [322], 'study': [323], 'was': [324, 347, 379, 390, 436], 'designed': [325], 'investigate': [327], 'human': [334], 'biological': [338], 'function': [339], 'cells.': [342], 'The': [343, 356, 409], 'examined': [348], 'by': [349], 'immunohistochemistry': [350], '191': [352], 'surgically': [353], 'resected': [354], 'ECs.': [355], 'associations': [357], 'between': [358], 'pathological': [363], 'parameters': [364], 'prognostic': [367, 475], 'value': [368], 'were': [371], 'analyzed.': [372], 'Western': [373], 'blot': [374], 'analysis': [375, 431], 'showed': [376, 432], 'that': [377, 413, 433, 461], 'overexpressed': [380], 'cell': [383, 454], 'lines.': [384], 'In': [385], 'addition,': [386], 'positive': [387], 'strongly': [391], 'related': [392], 'advanced': [394], 'stage': [396], '(': [397, 404, 426], 'P': [398, 405, 427], '<0.01),': [399, 428], 'lymph': [401], 'node': [402], 'metastasis': [403], '<0.01)': [406], 'EC.': [408], 'Kaplan-Meier': [410], 'curve': [411], 'indicated': [412], 'may': [418], 'result': [419], 'poor': [421], 'patients': [425], 'multivariate': [430], 'overexpression': [435], 'an': [437], 'independent': [438], 'predictor': [439], 'overall': [441], 'survival.': [442], 'Furthermore,': [443], 'suppression': [444], 'cells': [449], 'increased': [450], 'apoptosis': [451], 'decreased': [453], 'proliferation': [455], 'invasion': [456], 'ability.': [457], 'Our': [458], 'results': [459], 'suggest': [460], 'target': [465], 'potential': [469], 'serve': [471], 'as': [472], 'novel': [474], 'biomarker': [476], 'pathogenesis.': [479]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2725954495', 'counts_by_year': [{'year': 2023, 'cited_by_count': 2}, {'year': 2021, 'cited_by_count': 3}, {'year': 2020, 'cited_by_count': 2}, {'year': 2019, 'cited_by_count': 1}, {'year': 2018, 'cited_by_count': 1}], 'updated_date': '2024-09-06T15:52:37.172101', 'created_date': '2017-07-14'}