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'carvedilol': [973, 1005, 1039], 'reflects': [974, 1206], 'fact': [976], 'some': [983, 1089], 'α-adrenergic': [984], 'blocking': [986], 'effect;': [987], 'consequence': [991], 'demonstrated': [996], 'left': [998, 2051], 'sympathetic': [1000, 1238, 1976, 2053], 'denervation.13,14': [1001], 'They': [1002], 'exerts': [1006], 'effect': [1009, 1028, 1036, 1064], 'stabilizing': [1011, 1074], 'increasing': [1015], 'Ca2+release.': [1020], 'show': [1024, 2200], 'salutary': [1027], 'β-blocker': [1030], 'class-wide': [1035], 'was': [1040, 1146], 'superior': [1041], 'propranolol': [1043], 'suppressing': [1047, 1066], 'arrhythmia': [1048, 1142, 1170], 'level.': [1056], 'Moreover,': [1057], 'seems': [1059], 'exert': [1061], 'activity': [1071], 'rather': [1072], 'than': [1073], 'receptor.': [1077], 'resolve': [1080], 'past': [1081], 'controversies': [1082], 'about': [1083], 'action': [1087], 'agents': [1090], 'efficacy.To': [1094], 'evaluate': [1095], 'prospectively': [1104], 'predicting': [1105, 1271], 'CPVT2,': [1110], 'then': [1114], 'compared': [1115], 'vitro': [1118], 'patient.': [1131], 'authors': [1133], 'significantly': [1137], 'reduced': [1138], 'isoproterenol': [1139], 'phenylephrine-induced': [1141], 'congruent': [1147], 'exercise': [1150], 'showing': [1153], 'ameliorated': [1158], 'exercise-induced': [1159, 1195, 1935], 'tachycardia.': [1161], 'Interestingly,': [1162], 'did': [1164], 'reduce': [1166], 'single-cell': [1173, 1733], 'level': [1174], 'clinically.': [1176, 1198], 'Propranolol': [1177], 'resulted': [1179], 'partial': [1181, 1200], 'reduction': [1182], 'burden': [1185], 'improvement': [1189], '(but': [1191], 'resolution': [1193], 'of)': [1194], 'success': [1201], 'therapies': [1204], 'used': [1205], 'difficulties': [1209], 'managing': [1211], 'disorders': [1213, 1376], 'when': [1214], 'homozygous': [1218], 'mutation,': [1222], 'increases': [1225], 'severity.': [1227], 'case': [1231], 'channelopathies': [1235], 'activation': [1239], 'main': [1242], 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'generalizable': [1368], 'larger': [1370, 1427], 'populations': [1371], 'inherited': [1375, 1673], 'CPVT.In': [1379], 'summary,': [1380], 'able': [1385], 'demonstrate': [1387], 'iPSC-derived': [1389, 1759, 2273], 'CPVT2.': [1397], 'Their': [1398], 'provides': [1400], 'mechanisms.': [1408], 'Future': [1409], 'improvements': [1410], 'maturation,17': [1413], 'optimization': [1414], 'protocols': [1416], 'faster': [1418], 'yield': [1419], 'iPSC-cardiomyocytes,18': [1421], 'establishing': [1423], 'biobanks': [1425], 'population': [1428], 'patients19': [1431], 'diseases.20': [1439], 'Bench-to-bedside': [1440], 'correlations': [1441], 'utilizing': [1442], 'become': [1445], 'future': [1449], 'cardiovascular': [1452, 1627], 'fully': [1455], 'leverage': [1456], 'broad': [1458], 'utility': [1459], 'model,': [1464], 'bringing': [1466], 'precision': [1467, 1563, 1626, 2236], 'medicine': [1468], 'closer': [1469], 'reality.1,4,21Sources': [1471], 'FundingWe': [1473], 'thank': [1474], 'funding': 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