Why the missing heritability might not be in the DNA

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Duration: 3 min 30 s
Description: There are four major hypotheses (H1, H2, H3, and H4) as to the source of missing heritability. We propose that estimates obtained from GWAS underestimate heritability by not taking into account non-DNA (epigenetic) sources of heritability. Taking those factors into account (H4) should result in increased heritability estimates.
Pierrick Bourrat; Qiaoying Lu; Eva Jablonka
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