Title: Inactivation of fatty acid synthase impairs hepatocarcinogenesis driven by AKT in mice
Abstract: Background: Cumulating evidence underlines the crucial role of aberrant lipid biosyntesis in human hepatocellular carcinoma (HCC). Here, we investigated the oncogenic potential of fatty acid synthase (FASN), the master regulator of de novo lipogenesis, in the mouse liver.
Publication Year: 2015
Publication Date: 2015-12-14
Language: en
Type: article
Indexed In: ['crossref']
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Cited By Count: 2
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