Publication Information

{'id': 'https://openalex.org/W2617882439', 'doi': 'https://doi.org/10.18632/oncotarget.18054', 'title': 'Multiple gene-specific DNA methylation in blood leukocytes and colorectal cancer risk: a case-control study in China', 'display_name': 'Multiple gene-specific DNA methylation in blood leukocytes and colorectal cancer risk: a case-control study in China', 'publication_year': 2017, 'publication_date': '2017-05-22', 'ids': {'openalex': 'https://openalex.org/W2617882439', 'doi': 'https://doi.org/10.18632/oncotarget.18054', 'mag': '2617882439', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/28977860', 'pmcid': 'https://www.ncbi.nlm.nih.gov/pmc/articles/5617420'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.18632/oncotarget.18054', 'pdf_url': 'http://www.oncotarget.com/index.php?journal=oncotarget&page=article&op=download&path%5B%5D=18054&path%5B%5D=57845', 'source': {'id': 'https://openalex.org/S126644158', 'display_name': 'Oncotarget', 'issn_l': '1949-2553', 'issn': ['1949-2553'], 'is_oa': True, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310316297', 'host_organization_name': 'Impact Journals LLC', 'host_organization_lineage': ['https://openalex.org/P4310316297'], 'host_organization_lineage_names': ['Impact Journals LLC'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'gold', 'oa_url': 'http://www.oncotarget.com/index.php?journal=oncotarget&page=article&op=download&path%5B%5D=18054&path%5B%5D=57845', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5059276926', 'display_name': 'Yupeng Liu', 'orcid': 'https://orcid.org/0000-0002-8652-1987'}, 'institutions': [{'id': 'https://openalex.org/I156144747', 'display_name': 'Harbin Medical University', 'ror': 'https://ror.org/05jscf583', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I156144747']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Yupeng Liu', 'raw_affiliation_strings': ["Department of Epidemiology, Public Health College, Harbin Medical University, Harbin 150081, Heilongjiang Province, The People's Republic of China"], 'affiliations': [{'raw_affiliation_string': "Department of Epidemiology, Public Health College, Harbin Medical University, Harbin 150081, Heilongjiang Province, The People's Republic of China", 'institution_ids': ['https://openalex.org/I156144747']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5101572768', 'display_name': 'Yibaina Wang', 'orcid': 'https://orcid.org/0000-0003-3651-4663'}, 'institutions': [{'id': 'https://openalex.org/I156144747', 'display_name': 'Harbin Medical University', 'ror': 'https://ror.org/05jscf583', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I156144747']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Yibaina Wang', 'raw_affiliation_strings': ["Department of Epidemiology, Public Health College, Harbin Medical University, Harbin 150081, Heilongjiang Province, The People's Republic of China"], 'affiliations': [{'raw_affiliation_string': "Department of Epidemiology, Public Health College, Harbin Medical University, Harbin 150081, Heilongjiang Province, The People's Republic of China", 'institution_ids': ['https://openalex.org/I156144747']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5041904059', 'display_name': 'Fulan Hu', 'orcid': 'https://orcid.org/0000-0002-2386-1503'}, 'institutions': [{'id': 'https://openalex.org/I156144747', 'display_name': 'Harbin Medical University', 'ror': 'https://ror.org/05jscf583', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I156144747']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Fulan Hu', 'raw_affiliation_strings': ["Department of Epidemiology, Public Health College, Harbin Medical University, Harbin 150081, Heilongjiang Province, The People's Republic of China"], 'affiliations': [{'raw_affiliation_string': "Department of Epidemiology, Public Health College, Harbin Medical University, Harbin 150081, Heilongjiang Province, The People's Republic of China", 'institution_ids': ['https://openalex.org/I156144747']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5012272710', 'display_name': 'Hongru Sun', 'orcid': 'https://orcid.org/0000-0003-3305-7786'}, 'institutions': [{'id': 'https://openalex.org/I156144747', 'display_name': 'Harbin Medical University', 'ror': 'https://ror.org/05jscf583', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I156144747']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Hongru Sun', 'raw_affiliation_strings': ["Department of Epidemiology, Public Health College, Harbin Medical University, Harbin 150081, Heilongjiang Province, The People's Republic of China"], 'affiliations': [{'raw_affiliation_string': "Department of Epidemiology, Public Health College, Harbin Medical University, Harbin 150081, Heilongjiang Province, The People's Republic of China", 'institution_ids': ['https://openalex.org/I156144747']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5071630800', 'display_name': 'Zuoming Zhang', 'orcid': 'https://orcid.org/0000-0002-5303-893X'}, 'institutions': [{'id': 'https://openalex.org/I156144747', 'display_name': 'Harbin Medical University', 'ror': 'https://ror.org/05jscf583', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I156144747']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Zuoming Zhang', 'raw_affiliation_strings': ["Department of Epidemiology, Public Health College, Harbin Medical University, Harbin 150081, Heilongjiang Province, The People's Republic of China"], 'affiliations': [{'raw_affiliation_string': "Department of Epidemiology, Public Health College, Harbin Medical University, Harbin 150081, Heilongjiang Province, The People's Republic of China", 'institution_ids': ['https://openalex.org/I156144747']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5100328997', 'display_name': 'Xuan Wang', 'orcid': 'https://orcid.org/0000-0002-3556-3239'}, 'institutions': [{'id': 'https://openalex.org/I156144747', 'display_name': 'Harbin Medical University', 'ror': 'https://ror.org/05jscf583', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I156144747']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Xuan Wang', 'raw_affiliation_strings': ['Department of Epidemiology, Public Health College, Harbin Medical University, Harbin 150081, Heilongjiang Province, The People’s Republic of China'], 'affiliations': [{'raw_affiliation_string': 'Department of Epidemiology, Public Health College, Harbin Medical University, Harbin 150081, Heilongjiang Province, The People’s Republic of China', 'institution_ids': ['https://openalex.org/I156144747']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5109084908', 'display_name': 'Xiang Luo', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I156144747', 'display_name': 'Harbin Medical University', 'ror': 'https://ror.org/05jscf583', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I156144747']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Xiang Luo', 'raw_affiliation_strings': ["Department of Epidemiology, Public Health College, Harbin Medical University, Harbin 150081, Heilongjiang Province, The People's Republic of China"], 'affiliations': [{'raw_affiliation_string': "Department of Epidemiology, Public Health College, Harbin Medical University, Harbin 150081, Heilongjiang Province, The People's Republic of China", 'institution_ids': ['https://openalex.org/I156144747']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5101667704', 'display_name': 'Lin Zhu', 'orcid': 'https://orcid.org/0009-0003-8358-6560'}, 'institutions': [{'id': 'https://openalex.org/I156144747', 'display_name': 'Harbin Medical University', 'ror': 'https://ror.org/05jscf583', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I156144747']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Lin Zhu', 'raw_affiliation_strings': ["Department of Epidemiology, Public Health College, Harbin Medical University, Harbin 150081, Heilongjiang Province, The People's Republic of China"], 'affiliations': [{'raw_affiliation_string': "Department of Epidemiology, Public Health College, Harbin Medical University, Harbin 150081, Heilongjiang Province, The People's Republic of China", 'institution_ids': ['https://openalex.org/I156144747']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5114391540', 'display_name': 'Rong Huang', 'orcid': 'https://orcid.org/0000-0003-0496-8628'}, 'institutions': [{'id': 'https://openalex.org/I156144747', 'display_name': 'Harbin Medical University', 'ror': 'https://ror.org/05jscf583', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I156144747']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Rong Huang', 'raw_affiliation_strings': ["Department of Epidemiology, Public Health College, Harbin Medical University, Harbin 150081, Heilongjiang Province, The People's Republic of China"], 'affiliations': [{'raw_affiliation_string': "Department of Epidemiology, Public Health College, Harbin Medical University, Harbin 150081, Heilongjiang Province, The People's Republic of China", 'institution_ids': ['https://openalex.org/I156144747']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5101538538', 'display_name': 'Yan Li', 'orcid': 'https://orcid.org/0000-0001-8888-3386'}, 'institutions': [{'id': 'https://openalex.org/I156144747', 'display_name': 'Harbin Medical University', 'ror': 'https://ror.org/05jscf583', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I156144747']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Yan Li', 'raw_affiliation_strings': ['Department of Epidemiology, Public Health College, Harbin Medical University, Harbin 150081, Heilongjiang Province, The People’s Republic of China'], 'affiliations': [{'raw_affiliation_string': 'Department of Epidemiology, Public Health College, Harbin Medical University, Harbin 150081, Heilongjiang Province, The People’s Republic of China', 'institution_ids': ['https://openalex.org/I156144747']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5101407811', 'display_name': 'Guangxiao Li', 'orcid': 'https://orcid.org/0000-0002-8986-335X'}, 'institutions': [{'id': 'https://openalex.org/I156144747', 'display_name': 'Harbin Medical University', 'ror': 'https://ror.org/05jscf583', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I156144747']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Guangxiao Li', 'raw_affiliation_strings': ["Department of Epidemiology, Public Health College, Harbin Medical University, Harbin 150081, Heilongjiang Province, The People's Republic of China"], 'affiliations': [{'raw_affiliation_string': "Department of Epidemiology, Public Health College, Harbin Medical University, Harbin 150081, Heilongjiang Province, The People's Republic of China", 'institution_ids': ['https://openalex.org/I156144747']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5100445596', 'display_name': 'Xia Li', 'orcid': 'https://orcid.org/0000-0002-9794-2648'}, 'institutions': [{'id': 'https://openalex.org/I156144747', 'display_name': 'Harbin Medical University', 'ror': 'https://ror.org/05jscf583', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I156144747']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Xia Li', 'raw_affiliation_strings': ["Department of Epidemiology, Public Health College, Harbin Medical University, Harbin 150081, Heilongjiang Province, The People's Republic of China"], 'affiliations': [{'raw_affiliation_string': "Department of Epidemiology, Public Health College, Harbin Medical University, Harbin 150081, Heilongjiang Province, The People's Republic of China", 'institution_ids': ['https://openalex.org/I156144747']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5027692730', 'display_name': 'Shangqun Lin', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I156144747', 'display_name': 'Harbin Medical University', 'ror': 'https://ror.org/05jscf583', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I156144747']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Shangqun Lin', 'raw_affiliation_strings': ["Department of Epidemiology, Public Health College, Harbin Medical University, Harbin 150081, Heilongjiang Province, The People's Republic of China"], 'affiliations': [{'raw_affiliation_string': "Department of Epidemiology, Public Health College, Harbin Medical University, Harbin 150081, Heilongjiang Province, The People's Republic of China", 'institution_ids': ['https://openalex.org/I156144747']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5086183062', 'display_name': 'Fan Wang', 'orcid': 'https://orcid.org/0000-0002-9869-9504'}, 'institutions': [{'id': 'https://openalex.org/I156144747', 'display_name': 'Harbin Medical University', 'ror': 'https://ror.org/05jscf583', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I156144747']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Fan Wang', 'raw_affiliation_strings': ["Department of Epidemiology, Public Health College, Harbin Medical University, Harbin 150081, Heilongjiang Province, The People's Republic of China"], 'affiliations': [{'raw_affiliation_string': "Department of Epidemiology, Public Health College, Harbin Medical University, Harbin 150081, Heilongjiang Province, The People's Republic of China", 'institution_ids': ['https://openalex.org/I156144747']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5101442725', 'display_name': 'Yanhong Liu', 'orcid': 'https://orcid.org/0000-0002-2033-9242'}, 'institutions': [{'id': 'https://openalex.org/I156144747', 'display_name': 'Harbin Medical University', 'ror': 'https://ror.org/05jscf583', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I156144747']}, {'id': 'https://openalex.org/I4210132813', 'display_name': 'Second Affiliated Hospital of Harbin Medical University', 'ror': 'https://ror.org/03s8txj32', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210132813']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Yanhong Liu', 'raw_affiliation_strings': ["Department of Clinical Laboratory, The Second Affiliated Hospital of Harbin Medical University, Harbin 150081, Heilongjiang Province, The People's Republic of China", "Department of Epidemiology, Public Health College, Harbin Medical University, Harbin 150081, Heilongjiang Province, The People's Republic of China"], 'affiliations': [{'raw_affiliation_string': "Department of Epidemiology, Public Health College, Harbin Medical University, Harbin 150081, Heilongjiang Province, The People's Republic of China", 'institution_ids': ['https://openalex.org/I156144747']}, {'raw_affiliation_string': "Department of Clinical Laboratory, The Second Affiliated Hospital of Harbin Medical University, Harbin 150081, Heilongjiang Province, The People's Republic of China", 'institution_ids': ['https://openalex.org/I156144747', 'https://openalex.org/I4210132813']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5061429990', 'display_name': 'Jiesheng Rong', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210132813', 'display_name': 'Second Affiliated Hospital of Harbin Medical University', 'ror': 'https://ror.org/03s8txj32', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210132813']}, {'id': 'https://openalex.org/I156144747', 'display_name': 'Harbin Medical University', 'ror': 'https://ror.org/05jscf583', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I156144747']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Jiesheng Rong', 'raw_affiliation_strings': ["Department of Orthopedics Surgery, The Second Affiliated Hospital of Harbin Medical University, Harbin 150081, Heilongjiang Province, The People's Republic of China"], 'affiliations': [{'raw_affiliation_string': "Department of Orthopedics Surgery, The Second Affiliated Hospital of Harbin Medical University, Harbin 150081, Heilongjiang Province, The People's Republic of China", 'institution_ids': ['https://openalex.org/I4210132813', 'https://openalex.org/I156144747']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5101663699', 'display_name': 'Huiping Yuan', 'orcid': 'https://orcid.org/0000-0001-8750-6191'}, 'institutions': [{'id': 'https://openalex.org/I4210132813', 'display_name': 'Second Affiliated Hospital of Harbin Medical University', 'ror': 'https://ror.org/03s8txj32', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210132813']}, {'id': 'https://openalex.org/I156144747', 'display_name': 'Harbin Medical University', 'ror': 'https://ror.org/05jscf583', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I156144747']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Huiping Yuan', 'raw_affiliation_strings': ["Department of Epidemiology, Public Health College, Harbin Medical University, Harbin 150081, Heilongjiang Province, The People's Republic of China", "Key Laboratory of Ophthalmology, Department of Ophthalmology, The Second Affiliated Hospital of Harbin Medical University, Harbin 150081, Heilongjiang Province, The People's Republic of China"], 'affiliations': [{'raw_affiliation_string': "Key Laboratory of Ophthalmology, Department of Ophthalmology, The Second Affiliated Hospital of Harbin Medical University, Harbin 150081, Heilongjiang Province, The People's Republic of China", 'institution_ids': ['https://openalex.org/I4210132813', 'https://openalex.org/I156144747']}, {'raw_affiliation_string': "Department of Epidemiology, Public Health College, Harbin Medical University, Harbin 150081, Heilongjiang Province, The People's Republic of China", 'institution_ids': ['https://openalex.org/I156144747']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5009351025', 'display_name': 'Yashuang Zhao', 'orcid': 'https://orcid.org/0000-0002-7425-5773'}, 'institutions': [{'id': 'https://openalex.org/I156144747', 'display_name': 'Harbin Medical University', 'ror': 'https://ror.org/05jscf583', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I156144747']}], 'countries': ['CN'], 'is_corresponding': True, 'raw_author_name': 'Yashuang Zhao', 'raw_affiliation_strings': ["Department of Epidemiology, Public Health College, Harbin Medical University, Harbin 150081, Heilongjiang Province, The People's Republic of China"], 'affiliations': [{'raw_affiliation_string': "Department of Epidemiology, Public Health College, Harbin Medical University, Harbin 150081, Heilongjiang Province, The People's Republic of China", 'institution_ids': ['https://openalex.org/I156144747']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 2, 'corresponding_author_ids': ['https://openalex.org/A5009351025'], 'corresponding_institution_ids': ['https://openalex.org/I156144747'], 'apc_list': None, 'apc_paid': None, 'fwci': 0.815, 'has_fulltext': True, 'fulltext_origin': 'pdf', 'cited_by_count': 13, 'citation_normalized_percentile': {'value': 0.694668, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 87, 'max': 88}, 'biblio': {'volume': '8', 'issue': '37', 'first_page': '61239', 'last_page': '61252'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10269', 'display_name': 'Epigenetics and DNA Methylation', 'score': 0.9996, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10269', 'display_name': 'Epigenetics and DNA Methylation', 'score': 0.9996, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T11369', 'display_name': 'Genetic factors in colorectal cancer', 'score': 0.9975, 'subfield': {'id': 'https://openalex.org/subfields/2734', 'display_name': 'Pathology and Forensic Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10515', 'display_name': 'Cancer-related molecular mechanisms research', 'score': 0.994, 'subfield': {'id': 'https://openalex.org/subfields/1306', 'display_name': 'Cancer Research'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [], 'concepts': [{'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.65194154}, {'id': 'https://openalex.org/C526805850', 'wikidata': 'https://www.wikidata.org/wiki/Q188874', 'display_name': 'Colorectal cancer', 'level': 3, 'score': 0.6100064}, {'id': 'https://openalex.org/C33288867', 'wikidata': 'https://www.wikidata.org/wiki/Q518328', 'display_name': 'Methylation', 'level': 3, 'score': 0.52038085}, {'id': 'https://openalex.org/C190727270', 'wikidata': 'https://www.wikidata.org/wiki/Q874745', 'display_name': 'DNA methylation', 'level': 4, 'score': 0.5128982}, {'id': 'https://openalex.org/C191935318', 'wikidata': 'https://www.wikidata.org/wiki/Q148', 'display_name': 'China', 'level': 2, 'score': 0.48936027}, {'id': 'https://openalex.org/C107130276', 'wikidata': 'https://www.wikidata.org/wiki/Q133805', 'display_name': 'Epidemiology', 'level': 2, 'score': 0.42285836}, {'id': 'https://openalex.org/C143998085', 'wikidata': 'https://www.wikidata.org/wiki/Q162555', 'display_name': 'Oncology', 'level': 1, 'score': 0.4032079}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.3839354}, {'id': 'https://openalex.org/C121608353', 'wikidata': 'https://www.wikidata.org/wiki/Q12078', 'display_name': 'Cancer', 'level': 2, 'score': 0.372213}, {'id': 'https://openalex.org/C556039675', 'wikidata': 'https://www.wikidata.org/wiki/Q771035', 'display_name': 'Traditional medicine', 'level': 1, 'score': 0.36128995}, {'id': 'https://openalex.org/C512399662', 'wikidata': 'https://www.wikidata.org/wiki/Q3505712', 'display_name': 'Family medicine', 'level': 1, 'score': 0.34422123}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.16081172}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.13354695}, {'id': 'https://openalex.org/C54355233', 'wikidata': 'https://www.wikidata.org/wiki/Q7162', 'display_name': 'Genetics', 'level': 1, 'score': 0.11129108}, {'id': 'https://openalex.org/C205649164', 'wikidata': 'https://www.wikidata.org/wiki/Q1071', 'display_name': 'Geography', 'level': 0, 'score': 0.08706096}, {'id': 'https://openalex.org/C150194340', 'wikidata': 'https://www.wikidata.org/wiki/Q26972', 'display_name': 'Gene expression', 'level': 3, 'score': 0.0}, {'id': 'https://openalex.org/C166957645', 'wikidata': 'https://www.wikidata.org/wiki/Q23498', 'display_name': 'Archaeology', 'level': 1, 'score': 0.0}], 'mesh': [], 'locations_count': 4, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.18632/oncotarget.18054', 'pdf_url': 'http://www.oncotarget.com/index.php?journal=oncotarget&page=article&op=download&path%5B%5D=18054&path%5B%5D=57845', 'source': {'id': 'https://openalex.org/S126644158', 'display_name': 'Oncotarget', 'issn_l': '1949-2553', 'issn': ['1949-2553'], 'is_oa': True, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310316297', 'host_organization_name': 'Impact Journals LLC', 'host_organization_lineage': ['https://openalex.org/P4310316297'], 'host_organization_lineage_names': ['Impact Journals LLC'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://europepmc.org/articles/pmc5617420', 'pdf_url': 'https://europepmc.org/articles/pmc5617420?pdf=render', 'source': {'id': 'https://openalex.org/S4306400806', 'display_name': 'Europe PMC (PubMed Central)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1303153112', 'host_organization_name': 'European Bioinformatics Institute', 'host_organization_lineage': ['https://openalex.org/I1303153112'], 'host_organization_lineage_names': ['European Bioinformatics Institute'], 'type': 'repository'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5617420', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/28977860', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.18632/oncotarget.18054', 'pdf_url': 'http://www.oncotarget.com/index.php?journal=oncotarget&page=article&op=download&path%5B%5D=18054&path%5B%5D=57845', 'source': {'id': 'https://openalex.org/S126644158', 'display_name': 'Oncotarget', 'issn_l': '1949-2553', 'issn': ['1949-2553'], 'is_oa': True, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310316297', 'host_organization_name': 'Impact Journals LLC', 'host_organization_lineage': ['https://openalex.org/P4310316297'], 'host_organization_lineage_names': ['Impact Journals LLC'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [{'display_name': 'Good health and well-being', 'id': 'https://metadata.un.org/sdg/3', 'score': 0.85}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 88, 'referenced_works': ['https://openalex.org/W133930305', 'https://openalex.org/W1553454256', 'https://openalex.org/W1926715094', 'https://openalex.org/W1969534054', 'https://openalex.org/W1971279112', 'https://openalex.org/W1971358842', 'https://openalex.org/W1971708895', 'https://openalex.org/W1975678666', 'https://openalex.org/W1976726102', 'https://openalex.org/W1983319702', 'https://openalex.org/W1983751803', 'https://openalex.org/W1984625204', 'https://openalex.org/W1994214112', 'https://openalex.org/W1994237694', 'https://openalex.org/W1994682257', 'https://openalex.org/W1998953617', 'https://openalex.org/W1999668242', 'https://openalex.org/W2001288546', 'https://openalex.org/W2013343978', 'https://openalex.org/W2019702890', 'https://openalex.org/W2023449715', 'https://openalex.org/W2025135996', 'https://openalex.org/W2032829090', 'https://openalex.org/W2048103082', 'https://openalex.org/W2050259685', 'https://openalex.org/W2052334424', 'https://openalex.org/W2054241465', 'https://openalex.org/W2054742531', 'https://openalex.org/W2057769740', 'https://openalex.org/W2060332633', 'https://openalex.org/W2064915317', 'https://openalex.org/W2071041545', 'https://openalex.org/W2077359776', 'https://openalex.org/W2078120610', 'https://openalex.org/W2080840019', 'https://openalex.org/W2081358320', 'https://openalex.org/W2084174812', 'https://openalex.org/W2084790890', 'https://openalex.org/W2085446175', 'https://openalex.org/W2088716532', 'https://openalex.org/W2092245535', 'https://openalex.org/W2095668208', 'https://openalex.org/W2098442878', 'https://openalex.org/W2099879714', 'https://openalex.org/W2099982130', 'https://openalex.org/W2101612604', 'https://openalex.org/W2103033566', 'https://openalex.org/W2105020912', 'https://openalex.org/W2106421416', 'https://openalex.org/W2108064783', 'https://openalex.org/W2110762079', 'https://openalex.org/W2112677111', 'https://openalex.org/W2114339750', 'https://openalex.org/W2116483002', 'https://openalex.org/W2116514922', 'https://openalex.org/W2123837974', 'https://openalex.org/W2128091936', 'https://openalex.org/W2133766123', 'https://openalex.org/W2136732580', 'https://openalex.org/W2137180582', 'https://openalex.org/W2139122477', 'https://openalex.org/W2140638308', 'https://openalex.org/W2141410747', 'https://openalex.org/W2143366617', 'https://openalex.org/W2144723652', 'https://openalex.org/W2147518517', 'https://openalex.org/W2152286713', 'https://openalex.org/W2155195960', 'https://openalex.org/W2156930995', 'https://openalex.org/W2160372366', 'https://openalex.org/W2160385801', 'https://openalex.org/W2162915050', 'https://openalex.org/W2165560614', 'https://openalex.org/W2167021978', 'https://openalex.org/W2169903102', 'https://openalex.org/W2172283024', 'https://openalex.org/W2272984102', 'https://openalex.org/W2312460312', 'https://openalex.org/W2326023299', 'https://openalex.org/W2328176404', 'https://openalex.org/W2339678743', 'https://openalex.org/W2414471948', 'https://openalex.org/W2496824200', 'https://openalex.org/W2523285199', 'https://openalex.org/W2536579599', 'https://openalex.org/W2547187744', 'https://openalex.org/W2917837889', 'https://openalex.org/W4210458536'], 'related_works': ['https://openalex.org/W2902329290', 'https://openalex.org/W2221018455', 'https://openalex.org/W2151182744', 'https://openalex.org/W2128056428', 'https://openalex.org/W2107880877', 'https://openalex.org/W2054863651', 'https://openalex.org/W2052355316', 'https://openalex.org/W2046964473', 'https://openalex.org/W2024490794', 'https://openalex.org/W1998349112'], 'abstract_inverted_index': {'//': [0], 'Yupeng': [1], 'Liu': [2, 58], '1': [3, 7, 11, 15, 19, 23, 27, 31, 35, 39, 43, 47, 51, 55, 71, 72], ',': [4, 8, 12, 16, 20, 24, 28, 32, 36, 40, 44, 48, 52, 56, 60, 64], 'Yibaina': [5], 'Wang': [6, 22, 54], 'Fulan': [9], 'Hu': [10], 'Hongru': [13], 'Sun': [14], 'Zuoming': [17], 'Zhang': [18], 'Xuan': [21], 'Xiang': [25], 'Luo': [26], 'Lin': [29, 50], 'Zhu': [30], 'Rong': [33, 62], 'Huang': [34], 'Yan': [37], 'Li': [38, 42, 46], 'Guangxiao': [41], 'Xia': [45], 'Shangqun': [49], 'Fan': [53], 'Yanhong': [57], '2': [59, 91], 'Jiesheng': [61], '3': [63, 113], 'Huiping': [65], 'Yuan': [66], '4': [67, 135], 'and': [68, 196, 221, 252, 269, 278, 312, 315, 317, 322, 344, 348, 377], 'Yashuang': [69, 162], 'Zhao': [70], 'Department': [73, 92, 114, 140], 'of': [74, 89, 93, 100, 111, 115, 122, 133, 138, 141, 147, 158, 210, 213, 246, 249, 285, 354, 362, 375, 383], 'Epidemiology,': [75], 'Public': [76], 'Health': [77], 'College,': [78], 'Harbin': [79, 82, 101, 104, 123, 126, 148, 151], 'Medical': [80, 102, 124, 149], 'University,': [81, 103, 125, 150], '150081,': [83, 105, 127, 152], 'Heilongjiang': [84, 106, 128, 153], 'Province,': [85, 107, 129, 154], 'The': [86, 96, 108, 118, 130, 143, 155, 186, 327], "People's": [87, 109, 131, 156], 'Republic': [88, 110, 132, 157], 'China': [90, 112, 134, 159], 'Clinical': [94], 'Laboratory,': [95], 'Second': [97, 119, 144], 'Affiliated': [98, 120, 145], 'Hospital': [99, 121, 146], 'Orthopedics': [116], 'Surgery,': [117], 'Key': [136], 'Laboratory': [137], 'Ophthalmology,': [139, 142], 'Correspondence': [160], 'to:': [161], 'Zhao,': [163], 'email:': [164], '[email protected]': [165], 'Keywords:': [166], 'colorectal': [167, 197], 'cancer': [168, 198], 'risk,': [169], 'DNA': [170, 190, 365], 'methylation,': [171], 'leukocytes': [172, 195, 368], 'Received:': [173], 'February': [174], '03,': [175], '2017': [176, 180, 184], 'Accepted:': [177], 'April': [178], '07,': [179], 'Published:': [181], 'May': [182], '22,': [183], 'ABSTRACT': [185], 'relationship': [187], 'between': [188], 'gene-specific': [189, 364], 'methylation': [191, 208, 236, 244, 366], 'in': [192, 217, 309, 367], 'peripheral': [193], 'blood': [194], '(CRC)': [199], 'susceptibility': [200, 384], 'is': [201], 'unclear.': [202], 'In': [203], 'this': [204], 'case-control': [205], 'study,': [206], 'the': [207, 243, 247, 255, 289, 305, 330, 336, 345, 360, 373], 'status': [209, 245], 'a': [211, 234, 273, 380], 'panel': [212, 248, 361], '10': [214, 250, 363], 'CRC-related': [215], 'genes': [216, 251], '428': [218, 222], 'CRC': [219, 261, 290, 376], 'cases': [220], 'cancer-free': [223], 'controls': [224], 'were': [225], 'detected': [226], 'with': [227, 260, 264, 293, 372], 'methylation-sensitive': [228], 'high-resolution': [229], 'melting': [230], 'analysis.': [231], 'We': [232], 'calculated': [233], 'weighted': [235], 'risk': [237, 284, 291, 374], 'score': [238], '(MRS)': [239], 'that': [240, 254, 304], 'comprehensively': [241], 'combined': [242, 346], 'found': [253], 'MRS_10': [256, 295, 337, 349], 'was': [257, 339, 369], 'significantly': [258], 'associated': [259, 371], 'risk.': [262], 'Compared': [263], 'MRS-Low': [265], 'group,': [266], 'MRS-High': [267], 'group': [268, 271], 'MRS-Medium': [270], 'exhibited': [272], '6.51-fold': [274], '(95%': [275, 280, 341, 356], 'CI,': [276, 281, 342, 357], '3.77-11.27)': [277], '3.85-fold': [279], '2.72-5.45)': [282], 'increased': [283, 292], 'CRC,': [286], 'respectively.': [287], 'Moreover,': [288], 'increasing': [294], '(': [296], 'P': [297], 'trend': [298], '<': [299], '0.0001).': [300], 'Stratified': [301], 'analyses': [302], 'demonstrated': [303], 'significant': [306], 'association': [307], 'retained': [308], 'both': [310], 'men': [311], 'women,': [313], 'younger': [314], 'older,': [316], 'normal': [318], 'weight': [319], 'or': [320, 324], 'underweight': [321], 'overweight': [323], 'obese': [325], 'subjects.': [326], 'area': [328], 'under': [329], 'receiver': [331], 'operating': [332], 'characteristic': [333], 'curves': [334], 'for': [335, 385], 'model': [338, 350], '69.04%': [340], '65.57-72.66%)': [343], 'EF': [347], 'yielded': [351], 'an': [352], 'AUC': [353], '79.12%': [355], '76.22-82.15%).': [358], 'Together,': [359], 'strongly': [370], 'might': [378], 'be': [379], 'useful': [381], 'marker': [382], 'CRC.': [386]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2617882439', 'counts_by_year': [{'year': 2024, 'cited_by_count': 1}, {'year': 2023, 'cited_by_count': 2}, {'year': 2022, 'cited_by_count': 1}, {'year': 2021, 'cited_by_count': 1}, {'year': 2020, 'cited_by_count': 3}, {'year': 2019, 'cited_by_count': 5}], 'updated_date': '2024-12-24T11:30:59.125710', 'created_date': '2017-06-05'}