Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2617453476', 'doi': 'https://doi.org/10.15252/emmm.201607461', 'title': '<scp>SPINK</scp>2 deficiency causes infertility by inducing sperm defects in heterozygotes and azoospermia in homozygotes', 'display_name': '<scp>SPINK</scp>2 deficiency causes infertility by inducing sperm defects in heterozygotes and azoospermia in homozygotes', 'publication_year': 2017, 'publication_date': '2017-05-29', 'ids': {'openalex': 'https://openalex.org/W2617453476', 'doi': 'https://doi.org/10.15252/emmm.201607461', 'mag': '2617453476', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/28554943', 'pmcid': 'https://www.ncbi.nlm.nih.gov/pmc/articles/5538632'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.15252/emmm.201607461', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S163075119', 'display_name': 'EMBO Molecular Medicine', 'issn_l': '1757-4676', 'issn': ['1757-4676', '1757-4684'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310319965', 'host_organization_name': 'Springer Nature', 'host_organization_lineage': ['https://openalex.org/P4310319965'], 'host_organization_lineage_names': ['Springer Nature'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'gold', 'oa_url': 'https://doi.org/10.15252/emmm.201607461', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5069757119', 'display_name': 'Zine‐Eddine Kherraf', 'orcid': 'https://orcid.org/0000-0003-0351-6689'}, 'institutions': [{'id': 'https://openalex.org/I1294671590', 'display_name': 'Centre National de la Recherche Scientifique', 'ror': 'https://ror.org/02feahw73', 'country_code': 'FR', 'type': 'government', 'lineage': ['https://openalex.org/I1294671590']}, {'id': 'https://openalex.org/I4210152302', 'display_name': 'Institut de Biosciences et Biotechnologies', 'ror': 'https://ror.org/055wjj883', 'country_code': 'FR', 'type': 'facility', 'lineage': ['https://openalex.org/I2738703131', 'https://openalex.org/I4210091409', 'https://openalex.org/I4210152302']}, {'id': 'https://openalex.org/I4210160510', 'display_name': "Institut pour l'avancée des biosciences", 'ror': 'https://ror.org/05kwbf598', 'country_code': 'FR', 'type': 'facility', 'lineage': ['https://openalex.org/I1294671590', 'https://openalex.org/I154526488', 'https://openalex.org/I2800555055', 'https://openalex.org/I4210128919', 'https://openalex.org/I4210139971', 'https://openalex.org/I4210150872', 'https://openalex.org/I4210160510', 'https://openalex.org/I899635006']}, {'id': 'https://openalex.org/I154526488', 'display_name': 'Inserm', 'ror': 'https://ror.org/02vjkv261', 'country_code': 'FR', 'type': 'government', 'lineage': ['https://openalex.org/I154526488']}, {'id': 'https://openalex.org/I899635006', 'display_name': 'Université Grenoble Alpes', 'ror': 'https://ror.org/02rx3b187', 'country_code': 'FR', 'type': 'education', 'lineage': ['https://openalex.org/I899635006']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'Zine-Eddine Kherraf', 'raw_affiliation_strings': ["IAB - Institute for Advanced Biosciences / Institut pour l'Avancée des Biosciences (Grenoble) (Institut pour l'Avancée des Biosciences\r\nCentre de Recherche UGA / Inserm U 1209 / CNRS UMR 5309\r\nSite Santé - Allée des Alpes \r\n38700 La Tronche - France)"], 'affiliations': [{'raw_affiliation_string': "IAB - Institute for Advanced Biosciences / Institut pour l'Avancée des Biosciences (Grenoble) (Institut pour l'Avancée des Biosciences\r\nCentre de Recherche UGA / Inserm U 1209 / CNRS UMR 5309\r\nSite Santé - Allée des Alpes \r\n38700 La Tronche - France)", 'institution_ids': ['https://openalex.org/I1294671590', 'https://openalex.org/I4210152302', 'https://openalex.org/I4210160510', 'https://openalex.org/I154526488', 'https://openalex.org/I899635006']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5064877765', 'display_name': 'Marie Christou‐Kent', 'orcid': 'https://orcid.org/0000-0002-6008-7350'}, 'institutions': [{'id': 'https://openalex.org/I1294671590', 'display_name': 'Centre National de la Recherche Scientifique', 'ror': 'https://ror.org/02feahw73', 'country_code': 'FR', 'type': 'government', 'lineage': ['https://openalex.org/I1294671590']}, {'id': 'https://openalex.org/I4210152302', 'display_name': 'Institut de Biosciences et Biotechnologies', 'ror': 'https://ror.org/055wjj883', 'country_code': 'FR', 'type': 'facility', 'lineage': ['https://openalex.org/I2738703131', 'https://openalex.org/I4210091409', 'https://openalex.org/I4210152302']}, {'id': 'https://openalex.org/I4210160510', 'display_name': "Institut pour l'avancée des biosciences", 'ror': 'https://ror.org/05kwbf598', 'country_code': 'FR', 'type': 'facility', 'lineage': ['https://openalex.org/I1294671590', 'https://openalex.org/I154526488', 'https://openalex.org/I2800555055', 'https://openalex.org/I4210128919', 'https://openalex.org/I4210139971', 'https://openalex.org/I4210150872', 'https://openalex.org/I4210160510', 'https://openalex.org/I899635006']}, {'id': 'https://openalex.org/I154526488', 'display_name': 'Inserm', 'ror': 'https://ror.org/02vjkv261', 'country_code': 'FR', 'type': 'government', 'lineage': ['https://openalex.org/I154526488']}, {'id': 'https://openalex.org/I899635006', 'display_name': 'Université Grenoble Alpes', 'ror': 'https://ror.org/02rx3b187', 'country_code': 'FR', 'type': 'education', 'lineage': ['https://openalex.org/I899635006']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'Marie Christou-Kent', 'raw_affiliation_strings': ["IAB - Institute for Advanced Biosciences / Institut pour l'Avancée des Biosciences (Grenoble) (Institut pour l'Avancée des Biosciences\r\nCentre de Recherche UGA / Inserm U 1209 / CNRS UMR 5309\r\nSite Santé - Allée des Alpes \r\n38700 La Tronche - France)"], 'affiliations': [{'raw_affiliation_string': "IAB - Institute for Advanced Biosciences / Institut pour l'Avancée des Biosciences (Grenoble) (Institut pour l'Avancée des Biosciences\r\nCentre de Recherche UGA / Inserm U 1209 / CNRS UMR 5309\r\nSite Santé - Allée des Alpes \r\n38700 La Tronche - France)", 'institution_ids': ['https://openalex.org/I1294671590', 'https://openalex.org/I4210152302', 'https://openalex.org/I4210160510', 'https://openalex.org/I154526488', 'https://openalex.org/I899635006']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5086050335', 'display_name': 'Thomas Karaouzène', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I154526488', 'display_name': 'Inserm', 'ror': 'https://ror.org/02vjkv261', 'country_code': 'FR', 'type': 'government', 'lineage': ['https://openalex.org/I154526488']}, {'id': 'https://openalex.org/I899635006', 'display_name': 'Université Grenoble Alpes', 'ror': 'https://ror.org/02rx3b187', 'country_code': 'FR', 'type': 'education', 'lineage': ['https://openalex.org/I899635006']}, {'id': 'https://openalex.org/I4210136308', 'display_name': 'Translational Innovation in Medicine and Complexity', 'ror': 'https://ror.org/03985kf35', 'country_code': 'FR', 'type': 'facility', 'lineage': ['https://openalex.org/I106785703', 'https://openalex.org/I1294671590', 'https://openalex.org/I4210095849', 'https://openalex.org/I4210104684', 'https://openalex.org/I4210136308', 'https://openalex.org/I4210159245', 'https://openalex.org/I899635006']}, {'id': 'https://openalex.org/I1294671590', 'display_name': 'Centre National de la Recherche Scientifique', 'ror': 'https://ror.org/02feahw73', 'country_code': 'FR', 'type': 'government', 'lineage': ['https://openalex.org/I1294671590']}, {'id': 'https://openalex.org/I4210152302', 'display_name': 'Institut de Biosciences et Biotechnologies', 'ror': 'https://ror.org/055wjj883', 'country_code': 'FR', 'type': 'facility', 'lineage': ['https://openalex.org/I2738703131', 'https://openalex.org/I4210091409', 'https://openalex.org/I4210152302']}, {'id': 'https://openalex.org/I4210160510', 'display_name': "Institut pour l'avancée des biosciences", 'ror': 'https://ror.org/05kwbf598', 'country_code': 'FR', 'type': 'facility', 'lineage': ['https://openalex.org/I1294671590', 'https://openalex.org/I154526488', 'https://openalex.org/I2800555055', 'https://openalex.org/I4210128919', 'https://openalex.org/I4210139971', 'https://openalex.org/I4210150872', 'https://openalex.org/I4210160510', 'https://openalex.org/I899635006']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'Thomas Karaouzene', 'raw_affiliation_strings': ["IAB - Institute for Advanced Biosciences / Institut pour l'Avancée des Biosciences (Grenoble) (Institut pour l'Avancée des Biosciences\r\nCentre de Recherche UGA / Inserm U 1209 / CNRS UMR 5309\r\nSite Santé - Allée des Alpes \r\n38700 La Tronche - France)", 'TIMC-IMAG-BCM - Biologie Computationnelle et Mathématique (Domaine de la Merci, 38706 La Tronche, France - France)'], 'affiliations': [{'raw_affiliation_string': "IAB - Institute for Advanced Biosciences / Institut pour l'Avancée des Biosciences (Grenoble) (Institut pour l'Avancée des Biosciences\r\nCentre de Recherche UGA / Inserm U 1209 / CNRS UMR 5309\r\nSite Santé - Allée des Alpes \r\n38700 La Tronche - France)", 'institution_ids': ['https://openalex.org/I154526488', 'https://openalex.org/I899635006', 'https://openalex.org/I1294671590', 'https://openalex.org/I4210152302', 'https://openalex.org/I4210160510']}, {'raw_affiliation_string': 'TIMC-IMAG-BCM - Biologie Computationnelle et Mathématique (Domaine de la Merci, 38706 La Tronche, France - France)', 'institution_ids': ['https://openalex.org/I4210136308']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5046235987', 'display_name': 'Amir Amiri‐Yekta', 'orcid': 'https://orcid.org/0000-0002-8099-7984'}, 'institutions': [{'id': 'https://openalex.org/I1294671590', 'display_name': 'Centre National de la Recherche Scientifique', 'ror': 'https://ror.org/02feahw73', 'country_code': 'FR', 'type': 'government', 'lineage': ['https://openalex.org/I1294671590']}, {'id': 'https://openalex.org/I4210152302', 'display_name': 'Institut de Biosciences et Biotechnologies', 'ror': 'https://ror.org/055wjj883', 'country_code': 'FR', 'type': 'facility', 'lineage': ['https://openalex.org/I2738703131', 'https://openalex.org/I4210091409', 'https://openalex.org/I4210152302']}, {'id': 'https://openalex.org/I4210160510', 'display_name': "Institut pour l'avancée des biosciences", 'ror': 'https://ror.org/05kwbf598', 'country_code': 'FR', 'type': 'facility', 'lineage': ['https://openalex.org/I1294671590', 'https://openalex.org/I154526488', 'https://openalex.org/I2800555055', 'https://openalex.org/I4210128919', 'https://openalex.org/I4210139971', 'https://openalex.org/I4210150872', 'https://openalex.org/I4210160510', 'https://openalex.org/I899635006']}, {'id': 'https://openalex.org/I154526488', 'display_name': 'Inserm', 'ror': 'https://ror.org/02vjkv261', 'country_code': 'FR', 'type': 'government', 'lineage': ['https://openalex.org/I154526488']}, {'id': 'https://openalex.org/I899635006', 'display_name': 'Université Grenoble Alpes', 'ror': 'https://ror.org/02rx3b187', 'country_code': 'FR', 'type': 'education', 'lineage': ['https://openalex.org/I899635006']}, {'id': 'https://openalex.org/I4210099103', 'display_name': 'Département de Chimie Moléculaire', 'ror': 'https://ror.org/010rs2a38', 'country_code': 'FR', 'type': 'facility', 'lineage': ['https://openalex.org/I1294671590', 'https://openalex.org/I4210099103', 'https://openalex.org/I4210128300', 'https://openalex.org/I899635006']}, {'id': 'https://openalex.org/I2800555055', 'display_name': 'Centre Hospitalier Universitaire de Grenoble', 'ror': 'https://ror.org/041rhpw39', 'country_code': 'FR', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2800555055']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'Amir Amiri-Yekta', 'raw_affiliation_strings': ['Department of Genetics [Tehran, Iran] (P.O. Box: 16635-148, Tehran. - Iran)', "IAB - Institute for Advanced Biosciences / Institut pour l'Avancée des Biosciences (Grenoble) (Institut pour l'Avancée des Biosciences\r\nCentre de Recherche UGA / Inserm U 1209 / CNRS UMR 5309\r\nSite Santé - Allée des Alpes \r\n38700 La Tronche - France)", 'UF de Biochimie et Génétique Moléculaire [CHU Grenoble] (Grenoble, F-38000 - France)'], 'affiliations': [{'raw_affiliation_string': "IAB - Institute for Advanced Biosciences / Institut pour l'Avancée des Biosciences (Grenoble) (Institut pour l'Avancée des Biosciences\r\nCentre de Recherche UGA / Inserm U 1209 / CNRS UMR 5309\r\nSite Santé - Allée des Alpes \r\n38700 La Tronche - France)", 'institution_ids': ['https://openalex.org/I1294671590', 'https://openalex.org/I4210152302', 'https://openalex.org/I4210160510', 'https://openalex.org/I154526488', 'https://openalex.org/I899635006']}, {'raw_affiliation_string': 'UF de Biochimie et Génétique Moléculaire [CHU Grenoble] (Grenoble, F-38000 - France)', 'institution_ids': ['https://openalex.org/I4210099103', 'https://openalex.org/I2800555055']}, {'raw_affiliation_string': 'Department of Genetics [Tehran, Iran] (P.O. Box: 16635-148, Tehran. - Iran)', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5036547398', 'display_name': 'Guillaume Martinez', 'orcid': 'https://orcid.org/0000-0002-7572-9096'}, 'institutions': [{'id': 'https://openalex.org/I4210160510', 'display_name': "Institut pour l'avancée des biosciences", 'ror': 'https://ror.org/05kwbf598', 'country_code': 'FR', 'type': 'facility', 'lineage': ['https://openalex.org/I1294671590', 'https://openalex.org/I154526488', 'https://openalex.org/I2800555055', 'https://openalex.org/I4210128919', 'https://openalex.org/I4210139971', 'https://openalex.org/I4210150872', 'https://openalex.org/I4210160510', 'https://openalex.org/I899635006']}, {'id': 'https://openalex.org/I154526488', 'display_name': 'Inserm', 'ror': 'https://ror.org/02vjkv261', 'country_code': 'FR', 'type': 'government', 'lineage': ['https://openalex.org/I154526488']}, {'id': 'https://openalex.org/I899635006', 'display_name': 'Université Grenoble Alpes', 'ror': 'https://ror.org/02rx3b187', 'country_code': 'FR', 'type': 'education', 'lineage': ['https://openalex.org/I899635006']}, {'id': 'https://openalex.org/I1294671590', 'display_name': 'Centre National de la Recherche Scientifique', 'ror': 'https://ror.org/02feahw73', 'country_code': 'FR', 'type': 'government', 'lineage': ['https://openalex.org/I1294671590']}, {'id': 'https://openalex.org/I4210152302', 'display_name': 'Institut de Biosciences et Biotechnologies', 'ror': 'https://ror.org/055wjj883', 'country_code': 'FR', 'type': 'facility', 'lineage': ['https://openalex.org/I2738703131', 'https://openalex.org/I4210091409', 'https://openalex.org/I4210152302']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'Guillaume Martinez', 'raw_affiliation_strings': ["IAB - Institute for Advanced Biosciences / Institut pour l'Avancée des Biosciences (Grenoble) (Institut pour l'Avancée des Biosciences\r\nCentre de Recherche UGA / Inserm U 1209 / CNRS UMR 5309\r\nSite Santé - Allée des Alpes \r\n38700 La Tronche - France)"], 'affiliations': [{'raw_affiliation_string': "IAB - Institute for Advanced Biosciences / Institut pour l'Avancée des Biosciences (Grenoble) (Institut pour l'Avancée des Biosciences\r\nCentre de Recherche UGA / Inserm U 1209 / CNRS UMR 5309\r\nSite Santé - Allée des Alpes \r\n38700 La Tronche - France)", 'institution_ids': ['https://openalex.org/I4210160510', 'https://openalex.org/I154526488', 'https://openalex.org/I899635006', 'https://openalex.org/I1294671590', 'https://openalex.org/I4210152302']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5044806588', 'display_name': 'Alexandra Vargas', 'orcid': 'https://orcid.org/0000-0003-4441-4937'}, 'institutions': [{'id': 'https://openalex.org/I1294671590', 'display_name': 'Centre National de la Recherche Scientifique', 'ror': 'https://ror.org/02feahw73', 'country_code': 'FR', 'type': 'government', 'lineage': ['https://openalex.org/I1294671590']}, {'id': 'https://openalex.org/I4210152302', 'display_name': 'Institut de Biosciences et Biotechnologies', 'ror': 'https://ror.org/055wjj883', 'country_code': 'FR', 'type': 'facility', 'lineage': ['https://openalex.org/I2738703131', 'https://openalex.org/I4210091409', 'https://openalex.org/I4210152302']}, {'id': 'https://openalex.org/I4210160510', 'display_name': "Institut pour l'avancée des biosciences", 'ror': 'https://ror.org/05kwbf598', 'country_code': 'FR', 'type': 'facility', 'lineage': ['https://openalex.org/I1294671590', 'https://openalex.org/I154526488', 'https://openalex.org/I2800555055', 'https://openalex.org/I4210128919', 'https://openalex.org/I4210139971', 'https://openalex.org/I4210150872', 'https://openalex.org/I4210160510', 'https://openalex.org/I899635006']}, {'id': 'https://openalex.org/I154526488', 'display_name': 'Inserm', 'ror': 'https://ror.org/02vjkv261', 'country_code': 'FR', 'type': 'government', 'lineage': ['https://openalex.org/I154526488']}, {'id': 'https://openalex.org/I899635006', 'display_name': 'Université Grenoble Alpes', 'ror': 'https://ror.org/02rx3b187', 'country_code': 'FR', 'type': 'education', 'lineage': ['https://openalex.org/I899635006']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'Alexandra S. Vargas', 'raw_affiliation_strings': ["IAB - Institute for Advanced Biosciences / Institut pour l'Avancée des Biosciences (Grenoble) (Institut pour l'Avancée des Biosciences\r\nCentre de Recherche UGA / Inserm U 1209 / CNRS UMR 5309\r\nSite Santé - Allée des Alpes \r\n38700 La Tronche - France)"], 'affiliations': [{'raw_affiliation_string': "IAB - Institute for Advanced Biosciences / Institut pour l'Avancée des Biosciences (Grenoble) (Institut pour l'Avancée des Biosciences\r\nCentre de Recherche UGA / Inserm U 1209 / CNRS UMR 5309\r\nSite Santé - Allée des Alpes \r\n38700 La Tronche - France)", 'institution_ids': ['https://openalex.org/I1294671590', 'https://openalex.org/I4210152302', 'https://openalex.org/I4210160510', 'https://openalex.org/I154526488', 'https://openalex.org/I899635006']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5081084146', 'display_name': 'Emeline Lambert', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I1294671590', 'display_name': 'Centre National de la Recherche Scientifique', 'ror': 'https://ror.org/02feahw73', 'country_code': 'FR', 'type': 'government', 'lineage': ['https://openalex.org/I1294671590']}, {'id': 'https://openalex.org/I4210152302', 'display_name': 'Institut de Biosciences et Biotechnologies', 'ror': 'https://ror.org/055wjj883', 'country_code': 'FR', 'type': 'facility', 'lineage': ['https://openalex.org/I2738703131', 'https://openalex.org/I4210091409', 'https://openalex.org/I4210152302']}, {'id': 'https://openalex.org/I4210160510', 'display_name': "Institut pour l'avancée des biosciences", 'ror': 'https://ror.org/05kwbf598', 'country_code': 'FR', 'type': 'facility', 'lineage': ['https://openalex.org/I1294671590', 'https://openalex.org/I154526488', 'https://openalex.org/I2800555055', 'https://openalex.org/I4210128919', 'https://openalex.org/I4210139971', 'https://openalex.org/I4210150872', 'https://openalex.org/I4210160510', 'https://openalex.org/I899635006']}, {'id': 'https://openalex.org/I154526488', 'display_name': 'Inserm', 'ror': 'https://ror.org/02vjkv261', 'country_code': 'FR', 'type': 'government', 'lineage': ['https://openalex.org/I154526488']}, {'id': 'https://openalex.org/I899635006', 'display_name': 'Université Grenoble Alpes', 'ror': 'https://ror.org/02rx3b187', 'country_code': 'FR', 'type': 'education', 'lineage': ['https://openalex.org/I899635006']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'Emeline Lambert', 'raw_affiliation_strings': ["IAB - Institute for Advanced Biosciences / Institut pour l'Avancée des Biosciences (Grenoble) (Institut pour l'Avancée des Biosciences\r\nCentre de Recherche UGA / Inserm U 1209 / CNRS UMR 5309\r\nSite Santé - Allée des Alpes \r\n38700 La Tronche - France)"], 'affiliations': [{'raw_affiliation_string': "IAB - Institute for Advanced Biosciences / Institut pour l'Avancée des Biosciences (Grenoble) (Institut pour l'Avancée des Biosciences\r\nCentre de Recherche UGA / Inserm U 1209 / CNRS UMR 5309\r\nSite Santé - Allée des Alpes \r\n38700 La Tronche - France)", 'institution_ids': ['https://openalex.org/I1294671590', 'https://openalex.org/I4210152302', 'https://openalex.org/I4210160510', 'https://openalex.org/I154526488', 'https://openalex.org/I899635006']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5022209434', 'display_name': 'Christelle Borel', 'orcid': 'https://orcid.org/0000-0002-7525-9418'}, 'institutions': [], 'countries': ['CH'], 'is_corresponding': False, 'raw_author_name': 'Christelle Borel', 'raw_affiliation_strings': ['Department of Genetic Medicine and Development [Geneva, Switzerland] (rue Michel-Servet 1, 1211 Geneva. - Switzerland)'], 'affiliations': [{'raw_affiliation_string': 'Department of Genetic Medicine and Development [Geneva, Switzerland] (rue Michel-Servet 1, 1211 Geneva. - Switzerland)', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5046307945', 'display_name': 'B. Dorphin', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210137121', 'display_name': 'Amer Sports (France)', 'ror': 'https://ror.org/04e5zt867', 'country_code': 'FR', 'type': 'company', 'lineage': ['https://openalex.org/I4210137121', 'https://openalex.org/I4210144574']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'Beatrice Dorphin', 'raw_affiliation_strings': ['AMP 74 - Laboratoire d’Aide Médicale à la Procréation [CH Alpes-Léman] (558 route de Findrol - BP 20500 - 74130 Contamine sur Arve. - France)'], 'affiliations': [{'raw_affiliation_string': 'AMP 74 - Laboratoire d’Aide Médicale à la Procréation [CH Alpes-Léman] (558 route de Findrol - BP 20500 - 74130 Contamine sur Arve. - France)', 'institution_ids': ['https://openalex.org/I4210137121']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5040358711', 'display_name': 'Isabelle Aknin-Seifer', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210157006', 'display_name': 'Centre Hospitalier Universitaire de Saint-Étienne', 'ror': 'https://ror.org/04pn6vp43', 'country_code': 'FR', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210157006']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'Isabelle Aknin-Seifer', 'raw_affiliation_strings': ['Service de Biologie de la Reproduction [CHU Saint Etienne] (Centre Hospitalier Universitaire de Saint-Étienne - 42055 SAINT-ÉTIENNE Cedex 2 - France)'], 'affiliations': [{'raw_affiliation_string': 'Service de Biologie de la Reproduction [CHU Saint Etienne] (Centre Hospitalier Universitaire de Saint-Étienne - 42055 SAINT-ÉTIENNE Cedex 2 - France)', 'institution_ids': ['https://openalex.org/I4210157006']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5023223877', 'display_name': 'Colin E. Bishop', 'orcid': 'https://orcid.org/0000-0003-2052-7347'}, 'institutions': [{'id': 'https://openalex.org/I4210157800', 'display_name': 'Génétique Médicale & Génomique Fonctionelle', 'ror': 'https://ror.org/04fc8dp24', 'country_code': 'FR', 'type': 'facility', 'lineage': ['https://openalex.org/I154526488', 'https://openalex.org/I21491767', 'https://openalex.org/I4210111578', 'https://openalex.org/I4210157800']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'Michael J. Mitchell', 'raw_affiliation_strings': ['GMGF - Génétique Médicale et Génomique Fonctionnelle (Faculté de Médecine - 27 boulevard Jean Moulin 13385 Marseille Cedex 05 - France)'], 'affiliations': [{'raw_affiliation_string': 'GMGF - Génétique Médicale et Génomique Fonctionnelle (Faculté de Médecine - 27 boulevard Jean Moulin 13385 Marseille Cedex 05 - France)', 'institution_ids': ['https://openalex.org/I4210157800']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5029740596', 'display_name': 'Catherine Metzler‐Guillemain', 'orcid': 'https://orcid.org/0000-0002-1971-1932'}, 'institutions': [{'id': 'https://openalex.org/I4210157800', 'display_name': 'Génétique Médicale & Génomique Fonctionelle', 'ror': 'https://ror.org/04fc8dp24', 'country_code': 'FR', 'type': 'facility', 'lineage': ['https://openalex.org/I154526488', 'https://openalex.org/I21491767', 'https://openalex.org/I4210111578', 'https://openalex.org/I4210157800']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'Catherine Metzler-Guillemain', 'raw_affiliation_strings': ['GMGF - Génétique Médicale et Génomique Fonctionnelle (Faculté de Médecine - 27 boulevard Jean Moulin 13385 Marseille Cedex 05 - France)'], 'affiliations': [{'raw_affiliation_string': 'GMGF - Génétique Médicale et Génomique Fonctionnelle (Faculté de Médecine - 27 boulevard Jean Moulin 13385 Marseille Cedex 05 - France)', 'institution_ids': ['https://openalex.org/I4210157800']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5075089476', 'display_name': 'Jessica Escoffier', 'orcid': 'https://orcid.org/0000-0001-8166-5845'}, 'institutions': [{'id': 'https://openalex.org/I1294671590', 'display_name': 'Centre National de la Recherche Scientifique', 'ror': 'https://ror.org/02feahw73', 'country_code': 'FR', 'type': 'government', 'lineage': ['https://openalex.org/I1294671590']}, {'id': 'https://openalex.org/I4210152302', 'display_name': 'Institut de Biosciences et Biotechnologies', 'ror': 'https://ror.org/055wjj883', 'country_code': 'FR', 'type': 'facility', 'lineage': ['https://openalex.org/I2738703131', 'https://openalex.org/I4210091409', 'https://openalex.org/I4210152302']}, {'id': 'https://openalex.org/I4210160510', 'display_name': "Institut pour l'avancée des biosciences", 'ror': 'https://ror.org/05kwbf598', 'country_code': 'FR', 'type': 'facility', 'lineage': ['https://openalex.org/I1294671590', 'https://openalex.org/I154526488', 'https://openalex.org/I2800555055', 'https://openalex.org/I4210128919', 'https://openalex.org/I4210139971', 'https://openalex.org/I4210150872', 'https://openalex.org/I4210160510', 'https://openalex.org/I899635006']}, {'id': 'https://openalex.org/I154526488', 'display_name': 'Inserm', 'ror': 'https://ror.org/02vjkv261', 'country_code': 'FR', 'type': 'government', 'lineage': ['https://openalex.org/I154526488']}, {'id': 'https://openalex.org/I899635006', 'display_name': 'Université Grenoble Alpes', 'ror': 'https://ror.org/02rx3b187', 'country_code': 'FR', 'type': 'education', 'lineage': ['https://openalex.org/I899635006']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'Jessica Escoffier', 'raw_affiliation_strings': ["IAB - Institute for Advanced Biosciences / Institut pour l'Avancée des Biosciences (Grenoble) (Institut pour l'Avancée des Biosciences\r\nCentre de Recherche UGA / Inserm U 1209 / CNRS UMR 5309\r\nSite Santé - Allée des Alpes \r\n38700 La Tronche - France)"], 'affiliations': [{'raw_affiliation_string': "IAB - Institute for Advanced Biosciences / Institut pour l'Avancée des Biosciences (Grenoble) (Institut pour l'Avancée des Biosciences\r\nCentre de Recherche UGA / Inserm U 1209 / CNRS UMR 5309\r\nSite Santé - Allée des Alpes \r\n38700 La Tronche - France)", 'institution_ids': ['https://openalex.org/I1294671590', 'https://openalex.org/I4210152302', 'https://openalex.org/I4210160510', 'https://openalex.org/I154526488', 'https://openalex.org/I899635006']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5057345515', 'display_name': 'Serge Nef', 'orcid': 'https://orcid.org/0000-0001-5462-0676'}, 'institutions': [], 'countries': ['CH'], 'is_corresponding': False, 'raw_author_name': 'Serge Nef', 'raw_affiliation_strings': ['Department of Genetic Medicine and Development [Geneva, Switzerland] (rue Michel-Servet 1, 1211 Geneva. - Switzerland)'], 'affiliations': [{'raw_affiliation_string': 'Department of Genetic Medicine and Development [Geneva, Switzerland] (rue Michel-Servet 1, 1211 Geneva. - Switzerland)', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5017632187', 'display_name': 'Mariane Grepillat', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I1294671590', 'display_name': 'Centre National de la Recherche Scientifique', 'ror': 'https://ror.org/02feahw73', 'country_code': 'FR', 'type': 'government', 'lineage': ['https://openalex.org/I1294671590']}, {'id': 'https://openalex.org/I4210152302', 'display_name': 'Institut de Biosciences et Biotechnologies', 'ror': 'https://ror.org/055wjj883', 'country_code': 'FR', 'type': 'facility', 'lineage': ['https://openalex.org/I2738703131', 'https://openalex.org/I4210091409', 'https://openalex.org/I4210152302']}, {'id': 'https://openalex.org/I4210160510', 'display_name': "Institut pour l'avancée des biosciences", 'ror': 'https://ror.org/05kwbf598', 'country_code': 'FR', 'type': 'facility', 'lineage': ['https://openalex.org/I1294671590', 'https://openalex.org/I154526488', 'https://openalex.org/I2800555055', 'https://openalex.org/I4210128919', 'https://openalex.org/I4210139971', 'https://openalex.org/I4210150872', 'https://openalex.org/I4210160510', 'https://openalex.org/I899635006']}, {'id': 'https://openalex.org/I154526488', 'display_name': 'Inserm', 'ror': 'https://ror.org/02vjkv261', 'country_code': 'FR', 'type': 'government', 'lineage': ['https://openalex.org/I154526488']}, {'id': 'https://openalex.org/I899635006', 'display_name': 'Université Grenoble Alpes', 'ror': 'https://ror.org/02rx3b187', 'country_code': 'FR', 'type': 'education', 'lineage': ['https://openalex.org/I899635006']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'Mariane Grepillat', 'raw_affiliation_strings': ["IAB - Institute for Advanced Biosciences / Institut pour l'Avancée des Biosciences (Grenoble) (Institut pour l'Avancée des Biosciences\r\nCentre de Recherche UGA / Inserm U 1209 / CNRS UMR 5309\r\nSite Santé - Allée des Alpes \r\n38700 La Tronche - France)"], 'affiliations': [{'raw_affiliation_string': "IAB - Institute for Advanced Biosciences / Institut pour l'Avancée des Biosciences (Grenoble) (Institut pour l'Avancée des Biosciences\r\nCentre de Recherche UGA / Inserm U 1209 / CNRS UMR 5309\r\nSite Santé - Allée des Alpes \r\n38700 La Tronche - France)", 'institution_ids': ['https://openalex.org/I1294671590', 'https://openalex.org/I4210152302', 'https://openalex.org/I4210160510', 'https://openalex.org/I154526488', 'https://openalex.org/I899635006']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5050714674', 'display_name': 'Nicolas Thierry‐Mieg', 'orcid': 'https://orcid.org/0000-0002-7667-2853'}, 'institutions': [{'id': 'https://openalex.org/I4210136308', 'display_name': 'Translational Innovation in Medicine and Complexity', 'ror': 'https://ror.org/03985kf35', 'country_code': 'FR', 'type': 'facility', 'lineage': ['https://openalex.org/I106785703', 'https://openalex.org/I1294671590', 'https://openalex.org/I4210095849', 'https://openalex.org/I4210104684', 'https://openalex.org/I4210136308', 'https://openalex.org/I4210159245', 'https://openalex.org/I899635006']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'Nicolas Thierry-Mieg', 'raw_affiliation_strings': ['TIMC-IMAG-BCM - Biologie Computationnelle et Mathématique (Domaine de la Merci, 38706 La Tronche, France - France)'], 'affiliations': [{'raw_affiliation_string': 'TIMC-IMAG-BCM - Biologie Computationnelle et Mathématique (Domaine de la Merci, 38706 La Tronche, France - France)', 'institution_ids': ['https://openalex.org/I4210136308']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5031571999', 'display_name': 'Véronique Satre', 'orcid': 'https://orcid.org/0000-0001-7852-8591'}, 'institutions': [{'id': 'https://openalex.org/I1294671590', 'display_name': 'Centre National de la Recherche Scientifique', 'ror': 'https://ror.org/02feahw73', 'country_code': 'FR', 'type': 'government', 'lineage': ['https://openalex.org/I1294671590']}, {'id': 'https://openalex.org/I4210152302', 'display_name': 'Institut de Biosciences et Biotechnologies', 'ror': 'https://ror.org/055wjj883', 'country_code': 'FR', 'type': 'facility', 'lineage': ['https://openalex.org/I2738703131', 'https://openalex.org/I4210091409', 'https://openalex.org/I4210152302']}, {'id': 'https://openalex.org/I4210160510', 'display_name': "Institut pour l'avancée des biosciences", 'ror': 'https://ror.org/05kwbf598', 'country_code': 'FR', 'type': 'facility', 'lineage': ['https://openalex.org/I1294671590', 'https://openalex.org/I154526488', 'https://openalex.org/I2800555055', 'https://openalex.org/I4210128919', 'https://openalex.org/I4210139971', 'https://openalex.org/I4210150872', 'https://openalex.org/I4210160510', 'https://openalex.org/I899635006']}, {'id': 'https://openalex.org/I154526488', 'display_name': 'Inserm', 'ror': 'https://ror.org/02vjkv261', 'country_code': 'FR', 'type': 'government', 'lineage': ['https://openalex.org/I154526488']}, {'id': 'https://openalex.org/I899635006', 'display_name': 'Université Grenoble Alpes', 'ror': 'https://ror.org/02rx3b187', 'country_code': 'FR', 'type': 'education', 'lineage': ['https://openalex.org/I899635006']}, {'id': 'https://openalex.org/I2800555055', 'display_name': 'Centre Hospitalier Universitaire de Grenoble', 'ror': 'https://ror.org/041rhpw39', 'country_code': 'FR', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2800555055']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'Veronique Satre', 'raw_affiliation_strings': ["IAB - Institute for Advanced Biosciences / Institut pour l'Avancée des Biosciences (Grenoble) (Institut pour l'Avancée des Biosciences\r\nCentre de Recherche UGA / Inserm U 1209 / CNRS UMR 5309\r\nSite Santé - Allée des Alpes \r\n38700 La Tronche - France)", 'UF de Génétique Chromosomique [CHU Grenoble Alpes] (Avenue Maquis du Grésivaudan, 38700 La Tronche. - France)'], 'affiliations': [{'raw_affiliation_string': "IAB - Institute for Advanced Biosciences / Institut pour l'Avancée des Biosciences (Grenoble) (Institut pour l'Avancée des Biosciences\r\nCentre de Recherche UGA / Inserm U 1209 / CNRS UMR 5309\r\nSite Santé - Allée des Alpes \r\n38700 La Tronche - France)", 'institution_ids': ['https://openalex.org/I1294671590', 'https://openalex.org/I4210152302', 'https://openalex.org/I4210160510', 'https://openalex.org/I154526488', 'https://openalex.org/I899635006']}, {'raw_affiliation_string': 'UF de Génétique Chromosomique [CHU Grenoble Alpes] (Avenue Maquis du Grésivaudan, 38700 La Tronche. - France)', 'institution_ids': ['https://openalex.org/I2800555055']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5022341120', 'display_name': 'M. Bailly', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210109121', 'display_name': 'Centre Hospitalier Intercommunal de Poissy', 'ror': 'https://ror.org/015qy8r18', 'country_code': 'FR', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210109121']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'Marc Bailly', 'raw_affiliation_strings': ['Département de biologie de la reproduction et de gynécologie [CHIPS, Poissy] (30 Rue du Maréchal Galliēni, 78100 Saint-Germain-en-Laye. - France)', 'GIG - Gamètes, implantation, gestation (2 avenue de la Bièvre\r\n78180 Montigny le Bretonneux\r\n - France)'], 'affiliations': [{'raw_affiliation_string': 'Département de biologie de la reproduction et de gynécologie [CHIPS, Poissy] (30 Rue du Maréchal Galliēni, 78100 Saint-Germain-en-Laye. - France)', 'institution_ids': ['https://openalex.org/I4210109121']}, {'raw_affiliation_string': 'GIG - Gamètes, implantation, gestation (2 avenue de la Bièvre\r\n78180 Montigny le Bretonneux\r\n - France)', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5077219821', 'display_name': 'Florence Boitrelle', 'orcid': 'https://orcid.org/0000-0002-5322-0141'}, 'institutions': [{'id': 'https://openalex.org/I4210109121', 'display_name': 'Centre Hospitalier Intercommunal de Poissy', 'ror': 'https://ror.org/015qy8r18', 'country_code': 'FR', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210109121']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'Florence Boitrelle', 'raw_affiliation_strings': ['Département de biologie de la reproduction et de gynécologie [CHIPS, Poissy] (30 Rue du Maréchal Galliēni, 78100 Saint-Germain-en-Laye. - France)', 'GIG - Gamètes, implantation, gestation (2 avenue de la Bièvre\r\n78180 Montigny le Bretonneux\r\n - France)'], 'affiliations': [{'raw_affiliation_string': 'Département de biologie de la reproduction et de gynécologie [CHIPS, Poissy] (30 Rue du Maréchal Galliēni, 78100 Saint-Germain-en-Laye. - France)', 'institution_ids': ['https://openalex.org/I4210109121']}, {'raw_affiliation_string': 'GIG - Gamètes, implantation, gestation (2 avenue de la Bièvre\r\n78180 Montigny le Bretonneux\r\n - France)', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5085243858', 'display_name': 'Karin Pernet‐Gallay', 'orcid': 'https://orcid.org/0000-0003-3468-3316'}, 'institutions': [{'id': 'https://openalex.org/I4210151160', 'display_name': 'Grenoble Institute of Neurosciences', 'ror': 'https://ror.org/04as3rk94', 'country_code': 'FR', 'type': 'facility', 'lineage': ['https://openalex.org/I154526488', 'https://openalex.org/I2738703131', 'https://openalex.org/I4210151160', 'https://openalex.org/I899635006']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'Karin Pernet-Gallay', 'raw_affiliation_strings': ['GIN - [GIN] Grenoble Institut des Neurosciences (Site Santé - Bâtiment Edmond J. Safra - Chemin Fortuné Ferrini 38706 La Tronche Cedex - France)'], 'affiliations': [{'raw_affiliation_string': 'GIN - [GIN] Grenoble Institut des Neurosciences (Site Santé - Bâtiment Edmond J. Safra - Chemin Fortuné Ferrini 38706 La Tronche Cedex - France)', 'institution_ids': ['https://openalex.org/I4210151160']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5007735481', 'display_name': 'Sylviane Hennebicq', 'orcid': 'https://orcid.org/0000-0002-1851-6932'}, 'institutions': [{'id': 'https://openalex.org/I154526488', 'display_name': 'Inserm', 'ror': 'https://ror.org/02vjkv261', 'country_code': 'FR', 'type': 'government', 'lineage': ['https://openalex.org/I154526488']}, {'id': 'https://openalex.org/I899635006', 'display_name': 'Université Grenoble Alpes', 'ror': 'https://ror.org/02rx3b187', 'country_code': 'FR', 'type': 'education', 'lineage': ['https://openalex.org/I899635006']}, {'id': 'https://openalex.org/I2800555055', 'display_name': 'Centre Hospitalier Universitaire de Grenoble', 'ror': 'https://ror.org/041rhpw39', 'country_code': 'FR', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2800555055']}, {'id': 'https://openalex.org/I1294671590', 'display_name': 'Centre National de la Recherche Scientifique', 'ror': 'https://ror.org/02feahw73', 'country_code': 'FR', 'type': 'government', 'lineage': ['https://openalex.org/I1294671590']}, {'id': 'https://openalex.org/I4210152302', 'display_name': 'Institut de Biosciences et Biotechnologies', 'ror': 'https://ror.org/055wjj883', 'country_code': 'FR', 'type': 'facility', 'lineage': ['https://openalex.org/I2738703131', 'https://openalex.org/I4210091409', 'https://openalex.org/I4210152302']}, {'id': 'https://openalex.org/I4210160510', 'display_name': "Institut pour l'avancée des biosciences", 'ror': 'https://ror.org/05kwbf598', 'country_code': 'FR', 'type': 'facility', 'lineage': ['https://openalex.org/I1294671590', 'https://openalex.org/I154526488', 'https://openalex.org/I2800555055', 'https://openalex.org/I4210128919', 'https://openalex.org/I4210139971', 'https://openalex.org/I4210150872', 'https://openalex.org/I4210160510', 'https://openalex.org/I899635006']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'Sylviane Hennebicq', 'raw_affiliation_strings': ["IAB - Institute for Advanced Biosciences / Institut pour l'Avancée des Biosciences (Grenoble) (Institut pour l'Avancée des Biosciences\r\nCentre de Recherche UGA / Inserm U 1209 / CNRS UMR 5309\r\nSite Santé - Allée des Alpes \r\n38700 La Tronche - France)", 'UF de Biologie de la procréation [CHU Grenoble-Alpes] (Avenue Maquis du Grésivaudan, 38700 La Tronche. - France)'], 'affiliations': [{'raw_affiliation_string': "IAB - Institute for Advanced Biosciences / Institut pour l'Avancée des Biosciences (Grenoble) (Institut pour l'Avancée des Biosciences\r\nCentre de Recherche UGA / Inserm U 1209 / CNRS UMR 5309\r\nSite Santé - Allée des Alpes \r\n38700 La Tronche - France)", 'institution_ids': ['https://openalex.org/I154526488', 'https://openalex.org/I899635006', 'https://openalex.org/I1294671590', 'https://openalex.org/I4210152302', 'https://openalex.org/I4210160510']}, {'raw_affiliation_string': 'UF de Biologie de la procréation [CHU Grenoble-Alpes] (Avenue Maquis du Grésivaudan, 38700 La Tronche. - France)', 'institution_ids': ['https://openalex.org/I2800555055']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5025094834', 'display_name': 'Julien Fauré', 'orcid': 'https://orcid.org/0000-0002-3660-9809'}, 'institutions': [{'id': 'https://openalex.org/I4210099103', 'display_name': 'Département de Chimie Moléculaire', 'ror': 'https://ror.org/010rs2a38', 'country_code': 'FR', 'type': 'facility', 'lineage': ['https://openalex.org/I1294671590', 'https://openalex.org/I4210099103', 'https://openalex.org/I4210128300', 'https://openalex.org/I899635006']}, {'id': 'https://openalex.org/I2800555055', 'display_name': 'Centre Hospitalier Universitaire de Grenoble', 'ror': 'https://ror.org/041rhpw39', 'country_code': 'FR', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2800555055']}, {'id': 'https://openalex.org/I4210151160', 'display_name': 'Grenoble Institute of Neurosciences', 'ror': 'https://ror.org/04as3rk94', 'country_code': 'FR', 'type': 'facility', 'lineage': ['https://openalex.org/I154526488', 'https://openalex.org/I2738703131', 'https://openalex.org/I4210151160', 'https://openalex.org/I899635006']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'Julien Fauré', 'raw_affiliation_strings': ['GIN - [GIN] Grenoble Institut des Neurosciences (Site Santé - Bâtiment Edmond J. Safra - Chemin Fortuné Ferrini 38706 La Tronche Cedex - France)', 'UF de Biochimie et Génétique Moléculaire [CHU Grenoble] (Grenoble, F-38000 - France)'], 'affiliations': [{'raw_affiliation_string': 'UF de Biochimie et Génétique Moléculaire [CHU Grenoble] (Grenoble, F-38000 - France)', 'institution_ids': ['https://openalex.org/I4210099103', 'https://openalex.org/I2800555055']}, {'raw_affiliation_string': 'GIN - [GIN] Grenoble Institut des Neurosciences (Site Santé - Bâtiment Edmond J. Safra - Chemin Fortuné Ferrini 38706 La Tronche Cedex - France)', 'institution_ids': ['https://openalex.org/I4210151160']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5079148010', 'display_name': 'Serge P. Bottari', 'orcid': 'https://orcid.org/0000-0002-4172-2400'}, 'institutions': [{'id': 'https://openalex.org/I1294671590', 'display_name': 'Centre National de la Recherche Scientifique', 'ror': 'https://ror.org/02feahw73', 'country_code': 'FR', 'type': 'government', 'lineage': ['https://openalex.org/I1294671590']}, {'id': 'https://openalex.org/I4210152302', 'display_name': 'Institut de Biosciences et Biotechnologies', 'ror': 'https://ror.org/055wjj883', 'country_code': 'FR', 'type': 'facility', 'lineage': ['https://openalex.org/I2738703131', 'https://openalex.org/I4210091409', 'https://openalex.org/I4210152302']}, {'id': 'https://openalex.org/I154526488', 'display_name': 'Inserm', 'ror': 'https://ror.org/02vjkv261', 'country_code': 'FR', 'type': 'government', 'lineage': ['https://openalex.org/I154526488']}, {'id': 'https://openalex.org/I899635006', 'display_name': 'Université Grenoble Alpes', 'ror': 'https://ror.org/02rx3b187', 'country_code': 'FR', 'type': 'education', 'lineage': ['https://openalex.org/I899635006']}, {'id': 'https://openalex.org/I2800555055', 'display_name': 'Centre Hospitalier Universitaire de Grenoble', 'ror': 'https://ror.org/041rhpw39', 'country_code': 'FR', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2800555055']}, {'id': 'https://openalex.org/I4210160510', 'display_name': "Institut pour l'avancée des biosciences", 'ror': 'https://ror.org/05kwbf598', 'country_code': 'FR', 'type': 'facility', 'lineage': ['https://openalex.org/I1294671590', 'https://openalex.org/I154526488', 'https://openalex.org/I2800555055', 'https://openalex.org/I4210128919', 'https://openalex.org/I4210139971', 'https://openalex.org/I4210150872', 'https://openalex.org/I4210160510', 'https://openalex.org/I899635006']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'Serge P. Bottari', 'raw_affiliation_strings': ["IAB - Institute for Advanced Biosciences / Institut pour l'Avancée des Biosciences (Grenoble) (Institut pour l'Avancée des Biosciences\r\nCentre de Recherche UGA / Inserm U 1209 / CNRS UMR 5309\r\nSite Santé - Allée des Alpes \r\n38700 La Tronche - France)", 'UF de Radioanalyses [CHU Grenoble Alpes] (Avenue Maquis du Grésivaudan, 38700 La Tronche. - France)'], 'affiliations': [{'raw_affiliation_string': "IAB - Institute for Advanced Biosciences / Institut pour l'Avancée des Biosciences (Grenoble) (Institut pour l'Avancée des Biosciences\r\nCentre de Recherche UGA / Inserm U 1209 / CNRS UMR 5309\r\nSite Santé - Allée des Alpes \r\n38700 La Tronche - France)", 'institution_ids': ['https://openalex.org/I1294671590', 'https://openalex.org/I4210152302', 'https://openalex.org/I154526488', 'https://openalex.org/I899635006', 'https://openalex.org/I4210160510']}, {'raw_affiliation_string': 'UF de Radioanalyses [CHU Grenoble Alpes] (Avenue Maquis du Grésivaudan, 38700 La Tronche. - France)', 'institution_ids': ['https://openalex.org/I2800555055']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5042241430', 'display_name': 'Charles Coutton', 'orcid': 'https://orcid.org/0000-0002-8873-8098'}, 'institutions': [{'id': 'https://openalex.org/I1294671590', 'display_name': 'Centre National de la Recherche Scientifique', 'ror': 'https://ror.org/02feahw73', 'country_code': 'FR', 'type': 'government', 'lineage': ['https://openalex.org/I1294671590']}, {'id': 'https://openalex.org/I4210152302', 'display_name': 'Institut de Biosciences et Biotechnologies', 'ror': 'https://ror.org/055wjj883', 'country_code': 'FR', 'type': 'facility', 'lineage': ['https://openalex.org/I2738703131', 'https://openalex.org/I4210091409', 'https://openalex.org/I4210152302']}, {'id': 'https://openalex.org/I154526488', 'display_name': 'Inserm', 'ror': 'https://ror.org/02vjkv261', 'country_code': 'FR', 'type': 'government', 'lineage': ['https://openalex.org/I154526488']}, {'id': 'https://openalex.org/I899635006', 'display_name': 'Université Grenoble Alpes', 'ror': 'https://ror.org/02rx3b187', 'country_code': 'FR', 'type': 'education', 'lineage': ['https://openalex.org/I899635006']}, {'id': 'https://openalex.org/I2800555055', 'display_name': 'Centre Hospitalier Universitaire de Grenoble', 'ror': 'https://ror.org/041rhpw39', 'country_code': 'FR', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2800555055']}, {'id': 'https://openalex.org/I4210160510', 'display_name': "Institut pour l'avancée des biosciences", 'ror': 'https://ror.org/05kwbf598', 'country_code': 'FR', 'type': 'facility', 'lineage': ['https://openalex.org/I1294671590', 'https://openalex.org/I154526488', 'https://openalex.org/I2800555055', 'https://openalex.org/I4210128919', 'https://openalex.org/I4210139971', 'https://openalex.org/I4210150872', 'https://openalex.org/I4210160510', 'https://openalex.org/I899635006']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'Charles Coutton', 'raw_affiliation_strings': ["IAB - Institute for Advanced Biosciences / Institut pour l'Avancée des Biosciences (Grenoble) (Institut pour l'Avancée des Biosciences\r\nCentre de Recherche UGA / Inserm U 1209 / CNRS UMR 5309\r\nSite Santé - Allée des Alpes \r\n38700 La Tronche - France)", 'UF de Génétique Chromosomique [CHU Grenoble Alpes] (Avenue Maquis du Grésivaudan, 38700 La Tronche. - France)'], 'affiliations': [{'raw_affiliation_string': "IAB - Institute for Advanced Biosciences / Institut pour l'Avancée des Biosciences (Grenoble) (Institut pour l'Avancée des Biosciences\r\nCentre de Recherche UGA / Inserm U 1209 / CNRS UMR 5309\r\nSite Santé - Allée des Alpes \r\n38700 La Tronche - France)", 'institution_ids': ['https://openalex.org/I1294671590', 'https://openalex.org/I4210152302', 'https://openalex.org/I154526488', 'https://openalex.org/I899635006', 'https://openalex.org/I4210160510']}, {'raw_affiliation_string': 'UF de Génétique Chromosomique [CHU Grenoble Alpes] (Avenue Maquis du Grésivaudan, 38700 La Tronche. - France)', 'institution_ids': ['https://openalex.org/I2800555055']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5001457323', 'display_name': 'Pierre F. Ray', 'orcid': 'https://orcid.org/0000-0003-1544-7449'}, 'institutions': [{'id': 'https://openalex.org/I899635006', 'display_name': 'Université Grenoble Alpes', 'ror': 'https://ror.org/02rx3b187', 'country_code': 'FR', 'type': 'education', 'lineage': ['https://openalex.org/I899635006']}, {'id': 'https://openalex.org/I2800555055', 'display_name': 'Centre Hospitalier Universitaire de Grenoble', 'ror': 'https://ror.org/041rhpw39', 'country_code': 'FR', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2800555055']}, {'id': 'https://openalex.org/I4210160510', 'display_name': "Institut pour l'avancée des biosciences", 'ror': 'https://ror.org/05kwbf598', 'country_code': 'FR', 'type': 'facility', 'lineage': ['https://openalex.org/I1294671590', 'https://openalex.org/I154526488', 'https://openalex.org/I2800555055', 'https://openalex.org/I4210128919', 'https://openalex.org/I4210139971', 'https://openalex.org/I4210150872', 'https://openalex.org/I4210160510', 'https://openalex.org/I899635006']}, {'id': 'https://openalex.org/I154526488', 'display_name': 'Inserm', 'ror': 'https://ror.org/02vjkv261', 'country_code': 'FR', 'type': 'government', 'lineage': ['https://openalex.org/I154526488']}, {'id': 'https://openalex.org/I4210099103', 'display_name': 'Département de Chimie Moléculaire', 'ror': 'https://ror.org/010rs2a38', 'country_code': 'FR', 'type': 'facility', 'lineage': ['https://openalex.org/I1294671590', 'https://openalex.org/I4210099103', 'https://openalex.org/I4210128300', 'https://openalex.org/I899635006']}, {'id': 'https://openalex.org/I1294671590', 'display_name': 'Centre National de la Recherche Scientifique', 'ror': 'https://ror.org/02feahw73', 'country_code': 'FR', 'type': 'government', 'lineage': ['https://openalex.org/I1294671590']}, {'id': 'https://openalex.org/I4210152302', 'display_name': 'Institut de Biosciences et Biotechnologies', 'ror': 'https://ror.org/055wjj883', 'country_code': 'FR', 'type': 'facility', 'lineage': ['https://openalex.org/I2738703131', 'https://openalex.org/I4210091409', 'https://openalex.org/I4210152302']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'Pierre F. Ray', 'raw_affiliation_strings': ["IAB - Institute for Advanced Biosciences / Institut pour l'Avancée des Biosciences (Grenoble) (Institut pour l'Avancée des Biosciences\r\nCentre de Recherche UGA / Inserm U 1209 / CNRS UMR 5309\r\nSite Santé - Allée des Alpes \r\n38700 La Tronche - France)", 'UF de Biochimie et Génétique Moléculaire [CHU Grenoble] (Grenoble, F-38000 - France)'], 'affiliations': [{'raw_affiliation_string': "IAB - Institute for Advanced Biosciences / Institut pour l'Avancée des Biosciences (Grenoble) (Institut pour l'Avancée des Biosciences\r\nCentre de Recherche UGA / Inserm U 1209 / CNRS UMR 5309\r\nSite Santé - Allée des Alpes \r\n38700 La Tronche - France)", 'institution_ids': ['https://openalex.org/I899635006', 'https://openalex.org/I4210160510', 'https://openalex.org/I154526488', 'https://openalex.org/I1294671590', 'https://openalex.org/I4210152302']}, {'raw_affiliation_string': 'UF de Biochimie et Génétique Moléculaire [CHU Grenoble] (Grenoble, F-38000 - France)', 'institution_ids': ['https://openalex.org/I2800555055', 'https://openalex.org/I4210099103']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5064642133', 'display_name': 'Christophe Arnoult', 'orcid': 'https://orcid.org/0000-0002-3753-5901'}, 'institutions': [{'id': 'https://openalex.org/I4210160510', 'display_name': "Institut pour l'avancée des biosciences", 'ror': 'https://ror.org/05kwbf598', 'country_code': 'FR', 'type': 'facility', 'lineage': ['https://openalex.org/I1294671590', 'https://openalex.org/I154526488', 'https://openalex.org/I2800555055', 'https://openalex.org/I4210128919', 'https://openalex.org/I4210139971', 'https://openalex.org/I4210150872', 'https://openalex.org/I4210160510', 'https://openalex.org/I899635006']}, {'id': 'https://openalex.org/I154526488', 'display_name': 'Inserm', 'ror': 'https://ror.org/02vjkv261', 'country_code': 'FR', 'type': 'government', 'lineage': ['https://openalex.org/I154526488']}, {'id': 'https://openalex.org/I899635006', 'display_name': 'Université Grenoble Alpes', 'ror': 'https://ror.org/02rx3b187', 'country_code': 'FR', 'type': 'education', 'lineage': ['https://openalex.org/I899635006']}, {'id': 'https://openalex.org/I1294671590', 'display_name': 'Centre National de la Recherche Scientifique', 'ror': 'https://ror.org/02feahw73', 'country_code': 'FR', 'type': 'government', 'lineage': ['https://openalex.org/I1294671590']}, {'id': 'https://openalex.org/I4210152302', 'display_name': 'Institut de Biosciences et Biotechnologies', 'ror': 'https://ror.org/055wjj883', 'country_code': 'FR', 'type': 'facility', 'lineage': ['https://openalex.org/I2738703131', 'https://openalex.org/I4210091409', 'https://openalex.org/I4210152302']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'Christophe Arnoult', 'raw_affiliation_strings': ["IAB - Institute for Advanced Biosciences / Institut pour l'Avancée des Biosciences (Grenoble) (Institut pour l'Avancée des Biosciences\r\nCentre de Recherche UGA / Inserm U 1209 / CNRS UMR 5309\r\nSite Santé - Allée des Alpes \r\n38700 La Tronche - France)"], 'affiliations': [{'raw_affiliation_string': "IAB - Institute for Advanced Biosciences / Institut pour l'Avancée des Biosciences (Grenoble) (Institut pour l'Avancée des Biosciences\r\nCentre de Recherche UGA / Inserm U 1209 / CNRS UMR 5309\r\nSite Santé - Allée des Alpes \r\n38700 La Tronche - France)", 'institution_ids': ['https://openalex.org/I4210160510', 'https://openalex.org/I154526488', 'https://openalex.org/I899635006', 'https://openalex.org/I1294671590', 'https://openalex.org/I4210152302']}]}], 'institution_assertions': [], 'countries_distinct_count': 2, 'institutions_distinct_count': 13, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': {'value': 5000, 'currency': 'USD', 'value_usd': 5000, 'provenance': 'doaj'}, 'apc_paid': {'value': 5000, 'currency': 'USD', 'value_usd': 5000, 'provenance': 'doaj'}, 'fwci': 8.692, 'has_fulltext': True, 'fulltext_origin': 'pdf', 'cited_by_count': 101, 'citation_normalized_percentile': {'value': 0.999953, 'is_in_top_1_percent': True, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 98, 'max': 99}, 'biblio': {'volume': '9', 'issue': '8', 'first_page': '1132', 'last_page': '1149'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T12286', 'display_name': 'Mechanosensitive Ion Channels in Physiology and Disease', 'score': 0.9956, 'subfield': {'id': 'https://openalex.org/subfields/2737', 'display_name': 'Physiology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T12286', 'display_name': 'Mechanosensitive Ion Channels in Physiology and Disease', 'score': 0.9956, 'subfield': {'id': 'https://openalex.org/subfields/2737', 'display_name': 'Physiology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10760', 'display_name': 'Diagnosis and Management of Pancreatitis', 'score': 0.9939, 'subfield': {'id': 'https://openalex.org/subfields/2746', 'display_name': 'Surgery'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T12793', 'display_name': 'Biological Role of Caveolae in Cellular Processes', 'score': 0.9783, 'subfield': {'id': 'https://openalex.org/subfields/1307', 'display_name': 'Cell Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/heterozygote-advantage', 'display_name': 'Heterozygote advantage', 'score': 0.6650206}, {'id': 'https://openalex.org/keywords/sperm-dna-fragmentation', 'display_name': 'Sperm DNA Fragmentation', 'score': 0.55035}, {'id': 'https://openalex.org/keywords/sperm-quality', 'display_name': 'Sperm Quality', 'score': 0.51062}], 'concepts': [{'id': 'https://openalex.org/C2777420699', 'wikidata': 'https://www.wikidata.org/wiki/Q794026', 'display_name': 'Azoospermia', 'level': 4, 'score': 0.7580722}, {'id': 'https://openalex.org/C2777688143', 'wikidata': 'https://www.wikidata.org/wiki/Q179399', 'display_name': 'Infertility', 'level': 3, 'score': 0.70508546}, {'id': 'https://openalex.org/C153471976', 'wikidata': 'https://www.wikidata.org/wiki/Q2873354', 'display_name': 'Heterozygote advantage', 'level': 4, 'score': 0.6650206}, {'id': 'https://openalex.org/C16685009', 'wikidata': 'https://www.wikidata.org/wiki/Q335057', 'display_name': 'Andrology', 'level': 1, 'score': 0.6012118}, {'id': 'https://openalex.org/C2781087480', 'wikidata': 'https://www.wikidata.org/wiki/Q17145', 'display_name': 'Sperm', 'level': 2, 'score': 0.5462825}, {'id': 'https://openalex.org/C2777338322', 'wikidata': 'https://www.wikidata.org/wiki/Q280156', 'display_name': 'Male infertility', 'level': 4, 'score': 0.46288252}, {'id': 'https://openalex.org/C2776687438', 'wikidata': 'https://www.wikidata.org/wiki/Q3749492', 'display_name': 'Sterility', 'level': 2, 'score': 0.42063144}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.40146828}, {'id': 'https://openalex.org/C54355233', 'wikidata': 'https://www.wikidata.org/wiki/Q7162', 'display_name': 'Genetics', 'level': 1, 'score': 0.38428986}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.37415093}, {'id': 'https://openalex.org/C134018914', 'wikidata': 'https://www.wikidata.org/wiki/Q162606', 'display_name': 'Endocrinology', 'level': 1, 'score': 0.3324723}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.18910104}, {'id': 'https://openalex.org/C180754005', 'wikidata': 'https://www.wikidata.org/wiki/Q80726', 'display_name': 'Allele', 'level': 3, 'score': 0.1656839}, {'id': 'https://openalex.org/C2779234561', 'wikidata': 'https://www.wikidata.org/wiki/Q11995', 'display_name': 'Pregnancy', 'level': 2, 'score': 0.14838505}], 'mesh': [{'descriptor_ui': 'D053627', 'descriptor_name': 'Asthenozoospermia', 'qualifier_ui': 'Q000503', 'qualifier_name': 'physiopathology', 'is_major_topic': True}, {'descriptor_ui': 'D053627', 'descriptor_name': 'Asthenozoospermia', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': True}, {'descriptor_ui': 'D053713', 'descriptor_name': 'Azoospermia', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': True}, {'descriptor_ui': 'D053713', 'descriptor_name': 'Azoospermia', 'qualifier_ui': 'Q000503', 'qualifier_name': 'physiopathology', 'is_major_topic': True}, {'descriptor_ui': 'D006023', 'descriptor_name': 'Glycoproteins', 'qualifier_ui': 'Q000172', 'qualifier_name': 'deficiency', 'is_major_topic': True}, {'descriptor_ui': 'D000074162', 'descriptor_name': 'Serine Peptidase Inhibitors, Kazal Type', 'qualifier_ui': 'Q000172', 'qualifier_name': 'deficiency', 'is_major_topic': True}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D053627', 'descriptor_name': 'Asthenozoospermia', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D053713', 'descriptor_name': 'Azoospermia', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004195', 'descriptor_name': 'Disease Models, Animal', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006023', 'descriptor_name': 'Glycoproteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006579', 'descriptor_name': 'Heterozygote', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006720', 'descriptor_name': 'Homozygote', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008297', 'descriptor_name': 'Male', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D051379', 'descriptor_name': 'Mice', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D018345', 'descriptor_name': 'Mice, Knockout', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000074162', 'descriptor_name': 'Serine Peptidase Inhibitors, Kazal Type', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 4, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.15252/emmm.201607461', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S163075119', 'display_name': 'EMBO Molecular Medicine', 'issn_l': '1757-4676', 'issn': ['1757-4676', '1757-4684'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310319965', 'host_organization_name': 'Springer Nature', 'host_organization_lineage': ['https://openalex.org/P4310319965'], 'host_organization_lineage_names': ['Springer Nature'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://hal.science/hal-01741725', 'pdf_url': 'https://hal.science/hal-01741725/document', 'source': {'id': 'https://openalex.org/S4306402512', 'display_name': 'HAL (Le Centre pour la Communication Scientifique Directe)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1294671590', 'host_organization_name': 'Centre National de la Recherche Scientifique', 'host_organization_lineage': ['https://openalex.org/I1294671590'], 'host_organization_lineage_names': ['Centre National de la Recherche Scientifique'], 'type': 'repository'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5538632', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/28554943', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.15252/emmm.201607461', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S163075119', 'display_name': 'EMBO Molecular Medicine', 'issn_l': '1757-4676', 'issn': ['1757-4676', '1757-4684'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310319965', 'host_organization_name': 'Springer Nature', 'host_organization_lineage': ['https://openalex.org/P4310319965'], 'host_organization_lineage_names': ['Springer Nature'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [], 'grants': [{'funder': 'https://openalex.org/F4320320883', 'funder_display_name': 'Agence Nationale de la Recherche', 'award_id': 'GENOPAT‐2009‐ICG2I'}, {'funder': 'https://openalex.org/F4320320883', 'funder_display_name': 'Agence Nationale de la Recherche', 'award_id': 'PRTS‐2014‐MAS‐FLAGELLA'}], 'datasets': [], 'versions': [], 'referenced_works_count': 47, 'referenced_works': ['https://openalex.org/W1508970569', 'https://openalex.org/W1563800735', 'https://openalex.org/W1973609206', 'https://openalex.org/W1973632178', 'https://openalex.org/W1974427864', 'https://openalex.org/W1975534833', 'https://openalex.org/W1978695171', 'https://openalex.org/W1979715747', 'https://openalex.org/W1980996405', 'https://openalex.org/W1986499227', 'https://openalex.org/W1989609207', 'https://openalex.org/W2020259164', 'https://openalex.org/W2028748494', 'https://openalex.org/W2029036137', 'https://openalex.org/W2031724207', 'https://openalex.org/W2035557358', 'https://openalex.org/W2037485665', 'https://openalex.org/W2044088661', 'https://openalex.org/W2059355816', 'https://openalex.org/W2064397275', 'https://openalex.org/W2066449582', 'https://openalex.org/W2071646318', 'https://openalex.org/W2083174192', 'https://openalex.org/W2083445028', 'https://openalex.org/W2089334040', 'https://openalex.org/W2089436328', 'https://openalex.org/W2094809870', 'https://openalex.org/W2098346462', 'https://openalex.org/W2103665463', 'https://openalex.org/W2104628102', 'https://openalex.org/W2117086890', 'https://openalex.org/W2127911142', 'https://openalex.org/W2132658004', 'https://openalex.org/W2140766436', 'https://openalex.org/W2156400902', 'https://openalex.org/W2157938250', 'https://openalex.org/W2158162999', 'https://openalex.org/W2158899309', 'https://openalex.org/W2160577038', 'https://openalex.org/W2160903957', 'https://openalex.org/W2162190911', 'https://openalex.org/W2162395803', 'https://openalex.org/W2166011264', 'https://openalex.org/W2230734953', 'https://openalex.org/W3145949091', 'https://openalex.org/W327137974', 'https://openalex.org/W4240778206'], 'related_works': ['https://openalex.org/W3107319722', 'https://openalex.org/W3099375527', 'https://openalex.org/W3005126946', 'https://openalex.org/W2383649848', 'https://openalex.org/W2381930120', 'https://openalex.org/W2364379034', 'https://openalex.org/W2262973066', 'https://openalex.org/W2208175938', 'https://openalex.org/W2154865904', 'https://openalex.org/W2082930041'], 'abstract_inverted_index': {'Azoospermia,': [0], 'characterized': [1, 20], 'by': [2, 127], 'the': [3, 8, 30, 48, 93, 151], 'absence': [4, 94], 'of': [5, 14, 25, 32, 79, 95, 117], 'spermatozoa': [6, 82], 'in': [7, 37, 92, 120, 164, 168], 'ejaculate,': [9], 'is': [10, 141], 'a': [11, 18, 33, 40, 76, 84, 114, 158], 'common': [12], 'cause': [13], 'male': [15, 64, 73], 'infertility': [16], 'with': [17, 55], 'poorly': [19], 'etiology.': [21], 'Exome': [22], 'sequencing': [23], 'analysis': [24, 89], 'two': [26], 'azoospermic': [27], 'brothers': [28], 'allowed': [29], 'identification': [31], 'homozygous': [34, 61], 'splice': [35], 'mutation': [36], 'SPINK2,': [38], 'encoding': [39], 'serine': [41], 'protease': [42], 'inhibitor': [43], 'believed': [44], 'to': [45, 107, 143, 166], 'target': [46], 'acrosin,': [47], 'main': [49], 'sperm': [50, 86], 'acrosomal': [51], 'protease.': [52], 'In': [53], 'accord': [54], 'these': [56], 'findings,': [57], 'we': [58], 'observed': [59, 113], 'that': [60, 91, 124, 139, 154], 'Spink2': [62], 'KO': [63], 'mice': [65, 74], 'had': [66, 75], 'azoospermia.': [67], 'Moreover,': [68], 'despite': [69], 'normal': [70], 'fertility,': [71], 'heterozygous': [72], 'high': [77], 'rate': [78], 'morphologically': [80], 'abnormal': [81], 'and': [83, 102, 153], 'reduced': [85], 'motility.': [87], 'Further': [88], 'demonstrated': [90], 'Spink2,': [96], 'protease-induced': [97], 'stress': [98], 'initiates': [99], 'Golgi': [100], 'fragmentation': [101], 'prevents': [103], 'acrosome': [104, 152], 'biogenesis': [105], 'leading': [106], 'spermatid': [108], 'differentiation': [109], 'arrest.': [110], 'We': [111], 'also': [112], 'deleterious': [115], 'effect': [116, 123], 'acrosin': [118, 134], 'overexpression': [119], 'HEK': [121], 'cells,': [122], 'was': [125], 'alleviated': [126], 'SPINK2': [128, 140], 'coexpression': [129], 'confirming': [130], 'its': [131, 155], 'role': [132], 'as': [133], 'inhibitor.': [135], 'These': [136], 'results': [137], 'demonstrate': [138], 'necessary': [142], 'neutralize': [144], 'proteases': [145], 'during': [146], 'their': [147], 'cellular': [148], 'transit': [149], 'toward': [150], 'deficiency': [156], 'induces': [157], 'pathological': [159], 'continuum': [160], 'ranging': [161], 'from': [162], 'oligoasthenoteratozoospermia': [163], 'heterozygotes': [165], 'azoospermia': [167], 'homozygotes.': [169]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2617453476', 'counts_by_year': [{'year': 2024, 'cited_by_count': 3}, {'year': 2023, 'cited_by_count': 14}, {'year': 2022, 'cited_by_count': 17}, {'year': 2021, 'cited_by_count': 15}, {'year': 2020, 'cited_by_count': 16}, {'year': 2019, 'cited_by_count': 18}, {'year': 2018, 'cited_by_count': 16}, {'year': 2017, 'cited_by_count': 1}], 'updated_date': '2024-09-24T23:25:58.780272', 'created_date': '2017-06-05'}