Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2614007565', 'doi': 'https://doi.org/10.1007/s00204-017-1982-1', 'title': 'Hepatic glucuronidation of 4-tert-octylphenol in humans: inter-individual variability and responsible UDP-glucuronosyltransferase isoforms', 'display_name': 'Hepatic glucuronidation of 4-tert-octylphenol in humans: inter-individual variability and responsible UDP-glucuronosyltransferase isoforms', 'publication_year': 2017, 'publication_date': '2017-05-12', 'ids': {'openalex': 'https://openalex.org/W2614007565', 'doi': 'https://doi.org/10.1007/s00204-017-1982-1', 'mag': '2614007565', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/28500425'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1007/s00204-017-1982-1', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S87018847', 'display_name': 'Archives of Toxicology', 'issn_l': '0340-5761', 'issn': ['0340-5761', '1432-0738'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310319900', 'host_organization_name': 'Springer Science+Business Media', 'host_organization_lineage': ['https://openalex.org/P4310319965', 'https://openalex.org/P4310319900'], 'host_organization_lineage_names': ['Springer Nature', 'Springer Science+Business Media'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5111821872', 'display_name': 'Takashi Isobe', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I164131854', 'display_name': 'Yokohama University of Pharmacy', 'ror': 'https://ror.org/05s0z8a66', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I164131854']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Takashi Isobe', 'raw_affiliation_strings': ['Laboratory of Xenobiotic Metabolism, Department of Health Pharmacy, Yokohama University of Pharmacy, 601 Matano-cho, Totsuka-ku, Yokohama, 245-0066, Japan'], 'affiliations': [{'raw_affiliation_string': 'Laboratory of Xenobiotic Metabolism, Department of Health Pharmacy, Yokohama University of Pharmacy, 601 Matano-cho, Totsuka-ku, Yokohama, 245-0066, Japan', 'institution_ids': ['https://openalex.org/I164131854']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5014568389', 'display_name': 'Susumu Ohkawara', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I164131854', 'display_name': 'Yokohama University of Pharmacy', 'ror': 'https://ror.org/05s0z8a66', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I164131854']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Susumu Ohkawara', 'raw_affiliation_strings': ['Laboratory of Environmental Toxicology, Department of Health Pharmacy, Yokohama University of Pharmacy, 601 Matano-cho, Totsuka-ku, Yokohama, 245-0066, Japan'], 'affiliations': [{'raw_affiliation_string': 'Laboratory of Environmental Toxicology, Department of Health Pharmacy, Yokohama University of Pharmacy, 601 Matano-cho, Totsuka-ku, Yokohama, 245-0066, Japan', 'institution_ids': ['https://openalex.org/I164131854']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5079328937', 'display_name': 'Toshiko Tanaka‐Kagawa', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I164131854', 'display_name': 'Yokohama University of Pharmacy', 'ror': 'https://ror.org/05s0z8a66', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I164131854']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Toshiko Tanaka-Kagawa', 'raw_affiliation_strings': ['Laboratory of Environmental Toxicology, Department of Health Pharmacy, Yokohama University of Pharmacy, 601 Matano-cho, Totsuka-ku, Yokohama, 245-0066, Japan'], 'affiliations': [{'raw_affiliation_string': 'Laboratory of Environmental Toxicology, Department of Health Pharmacy, Yokohama University of Pharmacy, 601 Matano-cho, Totsuka-ku, Yokohama, 245-0066, Japan', 'institution_ids': ['https://openalex.org/I164131854']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5051741748', 'display_name': 'Hideto Jinno', 'orcid': 'https://orcid.org/0000-0002-1810-4962'}, 'institutions': [{'id': 'https://openalex.org/I96636082', 'display_name': 'Meijo University', 'ror': 'https://ror.org/04h42fc75', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I96636082']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Hideto Jinno', 'raw_affiliation_strings': ['Laboratory of Hygienic Chemistry, Faculty of Pharmacy, Meijo University, 150 Yagotoyama, Tempaku-ku, Nagoya, 468-8503, Japan'], 'affiliations': [{'raw_affiliation_string': 'Laboratory of Hygienic Chemistry, Faculty of Pharmacy, Meijo University, 150 Yagotoyama, Tempaku-ku, Nagoya, 468-8503, Japan', 'institution_ids': ['https://openalex.org/I96636082']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5027553836', 'display_name': 'Nobumitsu Hanioka', 'orcid': 'https://orcid.org/0000-0003-4121-119X'}, 'institutions': [{'id': 'https://openalex.org/I164131854', 'display_name': 'Yokohama University of Pharmacy', 'ror': 'https://ror.org/05s0z8a66', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I164131854']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Nobumitsu Hanioka', 'raw_affiliation_strings': ['Laboratory of Xenobiotic Metabolism, Department of Health Pharmacy, Yokohama University of Pharmacy, 601 Matano-cho, Totsuka-ku, Yokohama, 245-0066, Japan'], 'affiliations': [{'raw_affiliation_string': 'Laboratory of Xenobiotic Metabolism, Department of Health Pharmacy, Yokohama University of Pharmacy, 601 Matano-cho, Totsuka-ku, Yokohama, 245-0066, Japan', 'institution_ids': ['https://openalex.org/I164131854']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 2, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': {'value': 3990, 'currency': 'EUR', 'value_usd': 5290, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 0.249, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 5, 'citation_normalized_percentile': {'value': 0.638087, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 79, 'max': 81}, 'biblio': {'volume': '91', 'issue': '11', 'first_page': '3543', 'last_page': '3550'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10375', 'display_name': 'Pharmacogenetics and Drug Metabolism', 'score': 0.9997, 'subfield': {'id': 'https://openalex.org/subfields/3004', 'display_name': 'Pharmacology'}, 'field': {'id': 'https://openalex.org/fields/30', 'display_name': 'Pharmacology, Toxicology and Pharmaceutics'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10375', 'display_name': 'Pharmacogenetics and Drug Metabolism', 'score': 0.9997, 'subfield': {'id': 'https://openalex.org/subfields/3004', 'display_name': 'Pharmacology'}, 'field': {'id': 'https://openalex.org/fields/30', 'display_name': 'Pharmacology, Toxicology and Pharmaceutics'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10686', 'display_name': 'Effects and risks of endocrine disrupting chemicals', 'score': 0.996, 'subfield': {'id': 'https://openalex.org/subfields/2307', 'display_name': 'Health, Toxicology and Mutagenesis'}, 'field': {'id': 'https://openalex.org/fields/23', 'display_name': 'Environmental Science'}, 'domain': {'id': 'https://openalex.org/domains/3', 'display_name': 'Physical Sciences'}}, {'id': 'https://openalex.org/T10908', 'display_name': 'Analytical Chemistry and Chromatography', 'score': 0.9946, 'subfield': {'id': 'https://openalex.org/subfields/1607', 'display_name': 'Spectroscopy'}, 'field': {'id': 'https://openalex.org/fields/16', 'display_name': 'Chemistry'}, 'domain': {'id': 'https://openalex.org/domains/3', 'display_name': 'Physical Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/glucuronosyltransferase', 'display_name': 'Glucuronosyltransferase', 'score': 0.7575121}, {'id': 'https://openalex.org/keywords/ugt2b7', 'display_name': 'UGT2B7', 'score': 0.53506166}], 'concepts': [{'id': 'https://openalex.org/C2779907587', 'wikidata': 'https://www.wikidata.org/wiki/Q14901439', 'display_name': 'Glucuronidation', 'level': 4, 'score': 0.91850185}, {'id': 'https://openalex.org/C2781278898', 'wikidata': 'https://www.wikidata.org/wiki/Q419543', 'display_name': 'Glucuronosyltransferase', 'level': 4, 'score': 0.7575121}, {'id': 'https://openalex.org/C53345823', 'wikidata': 'https://www.wikidata.org/wiki/Q5531554', 'display_name': 'Gene isoform', 'level': 3, 'score': 0.67269105}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.54225475}, {'id': 'https://openalex.org/C2777469378', 'wikidata': 'https://www.wikidata.org/wiki/Q14907739', 'display_name': 'UGT2B7', 'level': 5, 'score': 0.53506166}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.43637902}, {'id': 'https://openalex.org/C181199279', 'wikidata': 'https://www.wikidata.org/wiki/Q8047', 'display_name': 'Enzyme', 'level': 2, 'score': 0.22365546}, {'id': 'https://openalex.org/C87644729', 'wikidata': 'https://www.wikidata.org/wiki/Q547502', 'display_name': 'Microsome', 'level': 3, 'score': 0.18020862}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.10547218}], 'mesh': [{'descriptor_ui': 'D014453', 'descriptor_name': 'Glucuronosyltransferase', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D008099', 'descriptor_name': 'Liver', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': True}, {'descriptor_ui': 'D008099', 'descriptor_name': 'Liver', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D010636', 'descriptor_name': 'Phenols', 'qualifier_ui': 'Q000493', 'qualifier_name': 'pharmacokinetics', 'is_major_topic': True}, {'descriptor_ui': 'D000293', 'descriptor_name': 'Adolescent', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000328', 'descriptor_name': 'Adult', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000368', 'descriptor_name': 'Aged', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001713', 'descriptor_name': 'Biphenyl Compounds', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001713', 'descriptor_name': 'Biphenyl Compounds', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D001713', 'descriptor_name': 'Biphenyl Compounds', 'qualifier_ui': 'Q000493', 'qualifier_name': 'pharmacokinetics', 'is_major_topic': False}, {'descriptor_ui': 'D004008', 'descriptor_name': 'Diclofenac', 'qualifier_ui': 'Q000493', 'qualifier_name': 'pharmacokinetics', 'is_major_topic': False}, {'descriptor_ui': 'D004008', 'descriptor_name': 'Diclofenac', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D052244', 'descriptor_name': 'Endocrine Disruptors', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D052244', 'descriptor_name': 'Endocrine Disruptors', 'qualifier_ui': 'Q000493', 'qualifier_name': 'pharmacokinetics', 'is_major_topic': False}, {'descriptor_ui': 'D005260', 'descriptor_name': 'Female', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D020719', 'descriptor_name': 'Glucuronides', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D020719', 'descriptor_name': 'Glucuronides', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D014453', 'descriptor_name': 'Glucuronosyltransferase', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D014453', 'descriptor_name': 'Glucuronosyltransferase', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008099', 'descriptor_name': 'Liver', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008297', 'descriptor_name': 'Male', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008862', 'descriptor_name': 'Microsomes, Liver', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': False}, {'descriptor_ui': 'D008862', 'descriptor_name': 'Microsomes, Liver', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D008862', 'descriptor_name': 'Microsomes, Liver', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008875', 'descriptor_name': 'Middle Aged', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D010636', 'descriptor_name': 'Phenols', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011994', 'descriptor_name': 'Recombinant Proteins', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D011994', 'descriptor_name': 'Recombinant Proteins', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D011994', 'descriptor_name': 'Recombinant Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1007/s00204-017-1982-1', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S87018847', 'display_name': 'Archives of Toxicology', 'issn_l': '0340-5761', 'issn': ['0340-5761', '1432-0738'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310319900', 'host_organization_name': 'Springer Science+Business Media', 'host_organization_lineage': ['https://openalex.org/P4310319965', 'https://openalex.org/P4310319900'], 'host_organization_lineage_names': ['Springer Nature', 'Springer Science+Business Media'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/28500425', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'score': 0.5, 'display_name': 'Clean water and sanitation', 'id': 'https://metadata.un.org/sdg/6'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 59, 'referenced_works': ['https://openalex.org/W134077589', 'https://openalex.org/W1768157180', 'https://openalex.org/W1855372530', 'https://openalex.org/W1926734136', 'https://openalex.org/W1963657798', 'https://openalex.org/W1983450831', 'https://openalex.org/W1985334643', 'https://openalex.org/W1986401222', 'https://openalex.org/W1986837154', 'https://openalex.org/W1994169557', 'https://openalex.org/W1995373280', 'https://openalex.org/W1995586718', 'https://openalex.org/W1995727180', 'https://openalex.org/W2001136277', 'https://openalex.org/W2006880847', 'https://openalex.org/W2011593270', 'https://openalex.org/W2020831992', 'https://openalex.org/W2023704290', 'https://openalex.org/W2028628438', 'https://openalex.org/W2029135376', 'https://openalex.org/W2040611122', 'https://openalex.org/W2043169601', 'https://openalex.org/W2043201950', 'https://openalex.org/W2043822514', 'https://openalex.org/W2044647771', 'https://openalex.org/W2048327703', 'https://openalex.org/W2048541287', 'https://openalex.org/W2052249356', 'https://openalex.org/W2058969649', 'https://openalex.org/W2060200728', 'https://openalex.org/W2061587734', 'https://openalex.org/W2063063216', 'https://openalex.org/W2067589028', 'https://openalex.org/W2067753015', 'https://openalex.org/W2068075375', 'https://openalex.org/W2068403848', 'https://openalex.org/W2069290661', 'https://openalex.org/W2069646787', 'https://openalex.org/W2070433988', 'https://openalex.org/W2071528896', 'https://openalex.org/W2073457937', 'https://openalex.org/W2080266891', 'https://openalex.org/W2081865041', 'https://openalex.org/W2087689847', 'https://openalex.org/W2093172984', 'https://openalex.org/W2096718798', 'https://openalex.org/W2106759719', 'https://openalex.org/W2114349412', 'https://openalex.org/W2121148242', 'https://openalex.org/W2129209794', 'https://openalex.org/W2135277692', 'https://openalex.org/W2137440382', 'https://openalex.org/W2154429654', 'https://openalex.org/W2166011949', 'https://openalex.org/W2272686432', 'https://openalex.org/W2315321951', 'https://openalex.org/W2319946012', 'https://openalex.org/W2475102176', 'https://openalex.org/W988420'], 'related_works': ['https://openalex.org/W2614007565', 'https://openalex.org/W2405358853', 'https://openalex.org/W2127974033', 'https://openalex.org/W2111495323', 'https://openalex.org/W2105026769', 'https://openalex.org/W2095892621', 'https://openalex.org/W2068909140', 'https://openalex.org/W2058870475', 'https://openalex.org/W2054706176', 'https://openalex.org/W2018491836'], 'abstract_inverted_index': None, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2614007565', 'counts_by_year': [{'year': 2024, 'cited_by_count': 1}, {'year': 2023, 'cited_by_count': 1}, {'year': 2019, 'cited_by_count': 1}], 'updated_date': '2024-12-21T16:24:52.235488', 'created_date': '2017-05-19'}