Title: Detection of hepatitis E Virus in archived serum samples of wild boar from Northern Germany
Abstract:Hepatitis E virus (HEV), the sole member of the unassigned Genus Hepevirus , caused several largeepidemic outbreaks of acute hepatitis in Asia, Africa and in Mexico. Many of the hepatitis E cases in C...Hepatitis E virus (HEV), the sole member of the unassigned Genus Hepevirus , caused several largeepidemic outbreaks of acute hepatitis in Asia, Africa and in Mexico. Many of the hepatitis E cases in CentralEurope (2007 in Germany: 72 notified cases) are infections imported from the endemic regions; however,there is increasing evidence of sporadic infections without a history of travel. HEV is mainly transmitted byfaecally contaminated water, but also by contaminated food. HEV strains closely related to human isolateshave been detected in several animal species, especially in pigs, indicating that HEV is a zoonotic virus.Using three different RT-PCR protocols, HEV-RNA was detected in 10 out of 189 serum samplescollected in 1995/1996 from wild boars in Germany. Sequence analysis indicates a close relationship withgenotype 3 isolates of pigs and humans from the Netherlands and Japan. The results indicate that HEV ispresent in Germany since more than 10 years and that wild boar may function as a reservoir for HEVRead More
Publication Year: 2008
Publication Date: 2008-01-01
Language: en
Type: article
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