Title: 657. Effects of Imipramine, Scopolamine, Ketamine, NR2B and P2X7 Antagonists in a Chronic Model of Stress (CMS)-Induced Anhedonia
Abstract: It is well accepted that it is difficult to model affective disorders. Since anhedonia is a major clinical feature of depression, the CMS model of anhedonia appears to be a relevant test system. The CMS-induced anhedonia can be reversed following a chronic application of established antidepressants but not by drugs devoid of clinical activity in depressed patients.
Publication Year: 2017
Publication Date: 2017-05-01
Language: en
Type: article
Indexed In: ['crossref']
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