Title: COMPARISON OF NALBUPHINE WITH 0.5% BUPIVACAINE AND NORMAL SALINE WITH 0.5% BUPIVACAINE FOR POST - OPERATIVE EPIDURAL ANALGESIA
Abstract: AIM: Our aim is to evaluate the role of Nalbuphine as an additive to Bupivacaine to increase the duration of analgesia postoperatively by epidural anaesthesia.METHODS: 60 patients randomly allocated into two groups, 30 patients in each of both sexes ranging from 18-50 yrs age group of ASA grade I and II, posted for lower abdominal surgeries using 0.2mg/kg of Nalbuphine (Made to 1ml) with 0.5% Bupivacaine 19ml in study group epidurally with control group 0.5% Bupivacaine with 1ml of normal saline.RESULT: Epidural Nalbuphine produces early onset of sensory blockade significantly at 3.23±0.97mins(Control group 15.30±2.97mins),and prolongs the duration of postoperative analgesia significantly up to 449.67±39.43mins.(Control group 185.93± 32.43mins).CONCLUSION: In conclusion epidural Nalbuphine 0.2mg/kg with 0.5% Bupivacaine produces early onset of analgesia and prolonged duration of analgesia compared with 0.5% Bupivacaine with Normal saline.