Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2597438135', 'doi': 'https://doi.org/10.18632/oncotarget.16519', 'title': 'A six-microRNA signature in plasma was identified as a potential biomarker in diagnosis of esophageal squamous cell carcinoma', 'display_name': 'A six-microRNA signature in plasma was identified as a potential biomarker in diagnosis of esophageal squamous cell carcinoma', 'publication_year': 2017, 'publication_date': '2017-03-23', 'ids': {'openalex': 'https://openalex.org/W2597438135', 'doi': 'https://doi.org/10.18632/oncotarget.16519', 'mag': '2597438135', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/28380431', 'pmcid': 'https://www.ncbi.nlm.nih.gov/pmc/articles/5470983'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.18632/oncotarget.16519', 'pdf_url': 'http://www.oncotarget.com/index.php?journal=oncotarget&page=article&op=download&path%5B%5D=16519&path%5B%5D=52836', 'source': {'id': 'https://openalex.org/S126644158', 'display_name': 'Oncotarget', 'issn_l': '1949-2553', 'issn': ['1949-2553'], 'is_oa': True, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310316297', 'host_organization_name': 'Impact Journals LLC', 'host_organization_lineage': ['https://openalex.org/P4310316297'], 'host_organization_lineage_names': ['Impact Journals LLC'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'gold', 'oa_url': 'http://www.oncotarget.com/index.php?journal=oncotarget&page=article&op=download&path%5B%5D=16519&path%5B%5D=52836', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5090567341', 'display_name': 'Xin Zhou', 'orcid': 'https://orcid.org/0000-0002-6566-9018'}, 'institutions': [{'id': 'https://openalex.org/I83519826', 'display_name': 'Nanjing Medical University', 'ror': 'https://ror.org/059gcgy73', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I83519826']}, {'id': 'https://openalex.org/I4210152119', 'display_name': 'Jiangsu Province Hospital', 'ror': 'https://ror.org/04py1g812', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210152119']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Xin Zhou', 'raw_affiliation_strings': ['Department of Oncology, First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, PR China'], 'affiliations': [{'raw_affiliation_string': 'Department of Oncology, First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, PR China', 'institution_ids': ['https://openalex.org/I83519826', 'https://openalex.org/I4210152119']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5100396390', 'display_name': 'Wei Wen', 'orcid': 'https://orcid.org/0000-0003-2753-3870'}, 'institutions': [{'id': 'https://openalex.org/I83519826', 'display_name': 'Nanjing Medical University', 'ror': 'https://ror.org/059gcgy73', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I83519826']}, {'id': 'https://openalex.org/I4210152119', 'display_name': 'Jiangsu Province Hospital', 'ror': 'https://ror.org/04py1g812', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210152119']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Wei Wen', 'raw_affiliation_strings': ['Department of Thoracic Surgery, First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, PR China'], 'affiliations': [{'raw_affiliation_string': 'Department of Thoracic Surgery, First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, PR China', 'institution_ids': ['https://openalex.org/I83519826', 'https://openalex.org/I4210152119']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5047585931', 'display_name': 'Jun Zhu', 'orcid': 'https://orcid.org/0000-0003-1824-7610'}, 'institutions': [{'id': 'https://openalex.org/I4210128482', 'display_name': 'Jiangsu Cancer Hospital', 'ror': 'https://ror.org/03108sf43', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210128482']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Jun Zhu', 'raw_affiliation_strings': ['Department of Radiation Oncology, Jiangsu Cancer Hospital, Nanjing 210009, PR China'], 'affiliations': [{'raw_affiliation_string': 'Department of Radiation Oncology, Jiangsu Cancer Hospital, Nanjing 210009, PR China', 'institution_ids': ['https://openalex.org/I4210128482']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5090245968', 'display_name': 'Zebo Huang', 'orcid': 'https://orcid.org/0000-0003-2431-3741'}, 'institutions': [{'id': 'https://openalex.org/I83519826', 'display_name': 'Nanjing Medical University', 'ror': 'https://ror.org/059gcgy73', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I83519826']}, {'id': 'https://openalex.org/I4210152119', 'display_name': 'Jiangsu Province Hospital', 'ror': 'https://ror.org/04py1g812', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210152119']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Zebo Huang', 'raw_affiliation_strings': ['Department of Oncology, First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, PR China'], 'affiliations': [{'raw_affiliation_string': 'Department of Oncology, First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, PR China', 'institution_ids': ['https://openalex.org/I83519826', 'https://openalex.org/I4210152119']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5100322321', 'display_name': 'Lan Zhang', 'orcid': 'https://orcid.org/0000-0003-1576-9018'}, 'institutions': [{'id': 'https://openalex.org/I83519826', 'display_name': 'Nanjing Medical University', 'ror': 'https://ror.org/059gcgy73', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I83519826']}, {'id': 'https://openalex.org/I4210152119', 'display_name': 'Jiangsu Province Hospital', 'ror': 'https://ror.org/04py1g812', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210152119']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Lan Zhang', 'raw_affiliation_strings': ['Department of Oncology, First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, PR China'], 'affiliations': [{'raw_affiliation_string': 'Department of Oncology, First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, PR China', 'institution_ids': ['https://openalex.org/I83519826', 'https://openalex.org/I4210152119']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5069869364', 'display_name': 'Huo Zhang', 'orcid': 'https://orcid.org/0000-0002-5453-0846'}, 'institutions': [{'id': 'https://openalex.org/I83519826', 'display_name': 'Nanjing Medical University', 'ror': 'https://ror.org/059gcgy73', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I83519826']}, {'id': 'https://openalex.org/I4210152119', 'display_name': 'Jiangsu Province Hospital', 'ror': 'https://ror.org/04py1g812', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210152119']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Huo Zhang', 'raw_affiliation_strings': ['Department of Oncology, First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, PR China'], 'affiliations': [{'raw_affiliation_string': 'Department of Oncology, First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, PR China', 'institution_ids': ['https://openalex.org/I83519826', 'https://openalex.org/I4210152119']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5025530383', 'display_name': 'Lian‐Wen Qi', 'orcid': 'https://orcid.org/0000-0003-0728-4475'}, 'institutions': [{'id': 'https://openalex.org/I161716053', 'display_name': 'China Pharmaceutical University', 'ror': 'https://ror.org/01sfm2718', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I161716053']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Lian-Wen Qi', 'raw_affiliation_strings': ['State Key Laboratory of Natural Medicines and Department of Pharmacognosy, China Pharmaceutical University, Nanjing 210009, PR China'], 'affiliations': [{'raw_affiliation_string': 'State Key Laboratory of Natural Medicines and Department of Pharmacognosy, China Pharmaceutical University, Nanjing 210009, PR China', 'institution_ids': ['https://openalex.org/I161716053']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5013077143', 'display_name': 'Xia Shan', 'orcid': 'https://orcid.org/0000-0002-7773-4622'}, 'institutions': [{'id': 'https://openalex.org/I83519826', 'display_name': 'Nanjing Medical University', 'ror': 'https://ror.org/059gcgy73', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I83519826']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Xia Shan', 'raw_affiliation_strings': ['Department of Respiration, The Affiliated Jiangning Hospital of Nanjing Medical University, Nanjing 210000, PR China'], 'affiliations': [{'raw_affiliation_string': 'Department of Respiration, The Affiliated Jiangning Hospital of Nanjing Medical University, Nanjing 210000, PR China', 'institution_ids': ['https://openalex.org/I83519826']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5029042943', 'display_name': 'Tongshan Wang', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I83519826', 'display_name': 'Nanjing Medical University', 'ror': 'https://ror.org/059gcgy73', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I83519826']}, {'id': 'https://openalex.org/I4210152119', 'display_name': 'Jiangsu Province Hospital', 'ror': 'https://ror.org/04py1g812', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210152119']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Tongshan Wang', 'raw_affiliation_strings': ['Department of Oncology, First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, PR China'], 'affiliations': [{'raw_affiliation_string': 'Department of Oncology, First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, PR China', 'institution_ids': ['https://openalex.org/I83519826', 'https://openalex.org/I4210152119']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5107072099', 'display_name': 'Wen‐Fang Cheng', 'orcid': 'https://orcid.org/0000-0002-3282-6304'}, 'institutions': [{'id': 'https://openalex.org/I83519826', 'display_name': 'Nanjing Medical University', 'ror': 'https://ror.org/059gcgy73', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I83519826']}, {'id': 'https://openalex.org/I4210152119', 'display_name': 'Jiangsu Province Hospital', 'ror': 'https://ror.org/04py1g812', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210152119']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Wenfang Cheng', 'raw_affiliation_strings': ['Department of Gastroenterology, First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, PR China'], 'affiliations': [{'raw_affiliation_string': 'Department of Gastroenterology, First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, PR China', 'institution_ids': ['https://openalex.org/I83519826', 'https://openalex.org/I4210152119']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5061559660', 'display_name': 'Dan‐Xia Zhu', 'orcid': 'https://orcid.org/0000-0003-3675-0922'}, 'institutions': [{'id': 'https://openalex.org/I3923682', 'display_name': 'Soochow University', 'ror': 'https://ror.org/05t8y2r12', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I3923682']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Danxia Zhu', 'raw_affiliation_strings': ['Department of Oncology, The Third Affiliated Hospital of Soochow University, Changzhou 213003, PR China'], 'affiliations': [{'raw_affiliation_string': 'Department of Oncology, The Third Affiliated Hospital of Soochow University, Changzhou 213003, PR China', 'institution_ids': ['https://openalex.org/I3923682']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5101859546', 'display_name': 'Yin Yin', 'orcid': 'https://orcid.org/0000-0001-8113-4278'}, 'institutions': [{'id': 'https://openalex.org/I83519826', 'display_name': 'Nanjing Medical University', 'ror': 'https://ror.org/059gcgy73', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I83519826']}, {'id': 'https://openalex.org/I4210152119', 'display_name': 'Jiangsu Province Hospital', 'ror': 'https://ror.org/04py1g812', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210152119']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Yin Yin', 'raw_affiliation_strings': ['Department of Obstetrics and Gynecology, First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, PR China'], 'affiliations': [{'raw_affiliation_string': 'Department of Obstetrics and Gynecology, First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, PR China', 'institution_ids': ['https://openalex.org/I83519826', 'https://openalex.org/I4210152119']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5100612715', 'display_name': 'Yan Chen', 'orcid': 'https://orcid.org/0009-0004-6856-263X'}, 'institutions': [{'id': 'https://openalex.org/I83519826', 'display_name': 'Nanjing Medical University', 'ror': 'https://ror.org/059gcgy73', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I83519826']}, {'id': 'https://openalex.org/I4210152119', 'display_name': 'Jiangsu Province Hospital', 'ror': 'https://ror.org/04py1g812', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210152119']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Yan Chen', 'raw_affiliation_strings': ['Department of Emergency, First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, PR China'], 'affiliations': [{'raw_affiliation_string': 'Department of Emergency, First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, PR China', 'institution_ids': ['https://openalex.org/I83519826', 'https://openalex.org/I4210152119']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5030950854', 'display_name': 'Wei Zhu', 'orcid': 'https://orcid.org/0000-0002-5744-5962'}, 'institutions': [{'id': 'https://openalex.org/I83519826', 'display_name': 'Nanjing Medical University', 'ror': 'https://ror.org/059gcgy73', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I83519826']}, {'id': 'https://openalex.org/I4210152119', 'display_name': 'Jiangsu Province Hospital', 'ror': 'https://ror.org/04py1g812', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210152119']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Wei Zhu', 'raw_affiliation_strings': ['Department of Oncology, First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, PR China'], 'affiliations': [{'raw_affiliation_string': 'Department of Oncology, First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, PR China', 'institution_ids': ['https://openalex.org/I83519826', 'https://openalex.org/I4210152119']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5030628537', 'display_name': 'Yongqian Shu', 'orcid': 'https://orcid.org/0000-0002-3034-685X'}, 'institutions': [{'id': 'https://openalex.org/I83519826', 'display_name': 'Nanjing Medical University', 'ror': 'https://ror.org/059gcgy73', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I83519826']}, {'id': 'https://openalex.org/I4210152119', 'display_name': 'Jiangsu Province Hospital', 'ror': 'https://ror.org/04py1g812', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210152119']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Yongqian Shu', 'raw_affiliation_strings': ['Cancer Center of Nanjing Medical University, Nanjing 210029, PR China', 'Department of Oncology, First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, PR China'], 'affiliations': [{'raw_affiliation_string': 'Department of Oncology, First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, PR China', 'institution_ids': ['https://openalex.org/I83519826', 'https://openalex.org/I4210152119']}, {'raw_affiliation_string': 'Cancer Center of Nanjing Medical University, Nanjing 210029, PR China', 'institution_ids': ['https://openalex.org/I83519826']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5100442332', 'display_name': 'Ping Liu', 'orcid': 'https://orcid.org/0000-0001-6882-3204'}, 'institutions': [{'id': 'https://openalex.org/I83519826', 'display_name': 'Nanjing Medical University', 'ror': 'https://ror.org/059gcgy73', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I83519826']}, {'id': 'https://openalex.org/I4210152119', 'display_name': 'Jiangsu Province Hospital', 'ror': 'https://ror.org/04py1g812', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210152119']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Ping Liu', 'raw_affiliation_strings': ['Cancer Center of Nanjing Medical University, Nanjing 210029, PR China', 'Department of Oncology, First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, PR China'], 'affiliations': [{'raw_affiliation_string': 'Department of Oncology, First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, PR China', 'institution_ids': ['https://openalex.org/I83519826', 'https://openalex.org/I4210152119']}, {'raw_affiliation_string': 'Cancer Center of Nanjing Medical University, Nanjing 210029, PR China', 'institution_ids': ['https://openalex.org/I83519826']}]}], 'countries_distinct_count': 1, 'institutions_distinct_count': 5, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 3.18, 'has_fulltext': True, 'fulltext_origin': 'pdf', 'cited_by_count': 64, 'citation_normalized_percentile': {'value': 0.999898, 'is_in_top_1_percent': True, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 97, 'max': 98}, 'biblio': {'volume': '8', 'issue': '21', 'first_page': '34468', 'last_page': '34480'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10062', 'display_name': 'MicroRNA Regulation in Cancer and Development', 'score': 0.9998, 'subfield': {'id': 'https://openalex.org/subfields/1306', 'display_name': 'Cancer Research'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10062', 'display_name': 'MicroRNA Regulation in Cancer and Development', 'score': 0.9998, 'subfield': {'id': 'https://openalex.org/subfields/1306', 'display_name': 'Cancer Research'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T11765', 'display_name': 'Biogenesis and Functions of Circular RNAs', 'score': 0.995, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10515', 'display_name': 'Role of Long Noncoding RNAs in Cancer and Development', 'score': 0.9948, 'subfield': {'id': 'https://openalex.org/subfields/1306', 'display_name': 'Cancer Research'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/cancer-biomarkers', 'display_name': 'Cancer Biomarkers', 'score': 0.519496}, {'id': 'https://openalex.org/keywords/micrornas', 'display_name': 'MicroRNAs', 'score': 0.500501}], 'concepts': [{'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.7466055}, {'id': 'https://openalex.org/C191935318', 'wikidata': 'https://www.wikidata.org/wiki/Q148', 'display_name': 'China', 'level': 2, 'score': 0.552365}, {'id': 'https://openalex.org/C2994415158', 'wikidata': 'https://www.wikidata.org/wiki/Q372701', 'display_name': 'Esophageal squamous cell carcinoma', 'level': 3, 'score': 0.525063}, {'id': 'https://openalex.org/C2780724011', 'wikidata': 'https://www.wikidata.org/wiki/Q1295316', 'display_name': 'Emergency department', 'level': 2, 'score': 0.50898504}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.46514145}, {'id': 'https://openalex.org/C2779742542', 'wikidata': 'https://www.wikidata.org/wiki/Q372701', 'display_name': 'Esophageal cancer', 'level': 3, 'score': 0.4609483}, {'id': 'https://openalex.org/C512399662', 'wikidata': 'https://www.wikidata.org/wiki/Q3505712', 'display_name': 'Family medicine', 'level': 1, 'score': 0.3868519}, {'id': 'https://openalex.org/C143998085', 'wikidata': 'https://www.wikidata.org/wiki/Q162555', 'display_name': 'Oncology', 'level': 1, 'score': 0.37566847}, {'id': 'https://openalex.org/C556039675', 'wikidata': 'https://www.wikidata.org/wiki/Q771035', 'display_name': 'Traditional medicine', 'level': 1, 'score': 0.36870778}, {'id': 'https://openalex.org/C61434518', 'wikidata': 'https://www.wikidata.org/wiki/Q932510', 'display_name': 'General surgery', 'level': 1, 'score': 0.36506113}, {'id': 'https://openalex.org/C121608353', 'wikidata': 'https://www.wikidata.org/wiki/Q12078', 'display_name': 'Cancer', 'level': 2, 'score': 0.30319804}, {'id': 'https://openalex.org/C159110408', 'wikidata': 'https://www.wikidata.org/wiki/Q121176', 'display_name': 'Nursing', 'level': 1, 'score': 0.10453218}, {'id': 'https://openalex.org/C17744445', 'wikidata': 'https://www.wikidata.org/wiki/Q36442', 'display_name': 'Political science', 'level': 0, 'score': 0.0}, {'id': 'https://openalex.org/C199539241', 'wikidata': 'https://www.wikidata.org/wiki/Q7748', 'display_name': 'Law', 'level': 1, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D014408', 'descriptor_name': 'Biomarkers, Tumor', 'qualifier_ui': 'Q000097', 'qualifier_name': 'blood', 'is_major_topic': True}, {'descriptor_ui': 'D002294', 'descriptor_name': 'Carcinoma, Squamous Cell', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': True}, {'descriptor_ui': 'D004938', 'descriptor_name': 'Esophageal Neoplasms', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': True}, {'descriptor_ui': 'D035683', 'descriptor_name': 'MicroRNAs', 'qualifier_ui': 'Q000097', 'qualifier_name': 'blood', 'is_major_topic': True}, {'descriptor_ui': 'D014408', 'descriptor_name': 'Biomarkers, Tumor', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D014408', 'descriptor_name': 'Biomarkers, Tumor', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002294', 'descriptor_name': 'Carcinoma, Squamous Cell', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002294', 'descriptor_name': 'Carcinoma, Squamous Cell', 'qualifier_ui': 'Q000097', 'qualifier_name': 'blood', 'is_major_topic': False}, {'descriptor_ui': 'D004938', 'descriptor_name': 'Esophageal Neoplasms', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004938', 'descriptor_name': 'Esophageal Neoplasms', 'qualifier_ui': 'Q000097', 'qualifier_name': 'blood', 'is_major_topic': False}, {'descriptor_ui': 'D000077277', 'descriptor_name': 'Esophageal Squamous Cell Carcinoma', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005260', 'descriptor_name': 'Female', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D020869', 'descriptor_name': 'Gene Expression Profiling', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015972', 'descriptor_name': 'Gene Expression Regulation, Neoplastic', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D053263', 'descriptor_name': 'Gene Regulatory Networks', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008297', 'descriptor_name': 'Male', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D035683', 'descriptor_name': 'MicroRNAs', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011379', 'descriptor_name': 'Prognosis', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D012372', 'descriptor_name': 'ROC Curve', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D016019', 'descriptor_name': 'Survival Analysis', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 4, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.18632/oncotarget.16519', 'pdf_url': 'http://www.oncotarget.com/index.php?journal=oncotarget&page=article&op=download&path%5B%5D=16519&path%5B%5D=52836', 'source': {'id': 'https://openalex.org/S126644158', 'display_name': 'Oncotarget', 'issn_l': '1949-2553', 'issn': ['1949-2553'], 'is_oa': True, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310316297', 'host_organization_name': 'Impact Journals LLC', 'host_organization_lineage': ['https://openalex.org/P4310316297'], 'host_organization_lineage_names': ['Impact Journals LLC'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://europepmc.org/articles/pmc5470983', 'pdf_url': 'https://europepmc.org/articles/pmc5470983?pdf=render', 'source': {'id': 'https://openalex.org/S4306400806', 'display_name': 'Europe PMC (PubMed Central)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1303153112', 'host_organization_name': 'European Bioinformatics Institute', 'host_organization_lineage': ['https://openalex.org/I1303153112'], 'host_organization_lineage_names': ['European Bioinformatics Institute'], 'type': 'repository'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5470983', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/28380431', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.18632/oncotarget.16519', 'pdf_url': 'http://www.oncotarget.com/index.php?journal=oncotarget&page=article&op=download&path%5B%5D=16519&path%5B%5D=52836', 'source': {'id': 'https://openalex.org/S126644158', 'display_name': 'Oncotarget', 'issn_l': '1949-2553', 'issn': ['1949-2553'], 'is_oa': True, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310316297', 'host_organization_name': 'Impact Journals LLC', 'host_organization_lineage': ['https://openalex.org/P4310316297'], 'host_organization_lineage_names': ['Impact Journals LLC'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [{'display_name': 'Good health and well-being', 'id': 'https://metadata.un.org/sdg/3', 'score': 0.48}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 61, 'referenced_works': ['https://openalex.org/W1590412095', 'https://openalex.org/W1634699770', 'https://openalex.org/W1755027692', 'https://openalex.org/W1757407923', 'https://openalex.org/W1768163319', 'https://openalex.org/W1909950785', 'https://openalex.org/W1958462865', 'https://openalex.org/W1962460712', 'https://openalex.org/W1964123846', 'https://openalex.org/W1969350389', 'https://openalex.org/W1983932066', 'https://openalex.org/W1984539796', 'https://openalex.org/W1985170944', 'https://openalex.org/W1987360584', 'https://openalex.org/W1991929626', 'https://openalex.org/W1994053306', 'https://openalex.org/W1994179903', 'https://openalex.org/W1995320913', 'https://openalex.org/W2005400333', 'https://openalex.org/W2008529756', 'https://openalex.org/W2011733142', 'https://openalex.org/W2012988913', 'https://openalex.org/W2014405568', 'https://openalex.org/W2014842418', 'https://openalex.org/W2024206172', 'https://openalex.org/W2032093760', 'https://openalex.org/W2032923154', 'https://openalex.org/W2040066648', 'https://openalex.org/W2041187014', 'https://openalex.org/W2045914559', 'https://openalex.org/W2050980456', 'https://openalex.org/W2059255307', 'https://openalex.org/W2062690993', 'https://openalex.org/W2069295843', 'https://openalex.org/W2074689365', 'https://openalex.org/W2078703870', 'https://openalex.org/W2083381199', 'https://openalex.org/W2097233439', 'https://openalex.org/W2109227959', 'https://openalex.org/W2115093090', 'https://openalex.org/W2116036884', 'https://openalex.org/W2119043140', 'https://openalex.org/W2126914289', 'https://openalex.org/W2128776855', 'https://openalex.org/W2135899969', 'https://openalex.org/W2138664009', 'https://openalex.org/W2143703527', 'https://openalex.org/W2151409420', 'https://openalex.org/W2151999148', 'https://openalex.org/W2170740525', 'https://openalex.org/W2192353848', 'https://openalex.org/W2272984102', 'https://openalex.org/W2335056534', 'https://openalex.org/W2346635146', 'https://openalex.org/W2399287952', 'https://openalex.org/W2411082790', 'https://openalex.org/W2413737165', 'https://openalex.org/W2418491336', 'https://openalex.org/W2462595973', 'https://openalex.org/W2699220065', 'https://openalex.org/W612945392'], 'related_works': ['https://openalex.org/W4384345078', 'https://openalex.org/W4252242999', 'https://openalex.org/W2891926379', 'https://openalex.org/W2769982907', 'https://openalex.org/W2384709362', 'https://openalex.org/W2354918530', 'https://openalex.org/W2085691574', 'https://openalex.org/W2079855793', 'https://openalex.org/W2062907270', 'https://openalex.org/W2061985929'], 'abstract_inverted_index': {'//': [0], 'Xin': [1], 'Zhou': [2], '1,': [3, 62, 67], '*': [4, 9, 14, 219], ',': [5, 10, 15, 19, 23, 27, 31, 35, 39, 43, 47, 51, 55, 59, 64], 'Wei': [6, 56, 229], 'Wen': [7], '2,': [8], 'Jun': [11], 'Zhu': [12, 45, 57], '3,': [13], 'Zebo': [16], 'Huang': [17], '1': [18, 22, 26, 38, 58, 69, 300], 'Lan': [20], 'Zhang': [21, 25], 'Huo': [24], 'Lian-Wen': [28], 'Qi': [29], '4': [30, 112], 'Xia': [32], 'Shan': [33], '5': [34, 130], 'Tongshan': [36], 'Wang': [37], 'Wenfang': [40], 'Cheng': [41], '6': [42, 146], 'Danxia': [44], '7': [46, 161], 'Yin': [48, 49], '8': [50, 176], 'Yan': [52], 'Chen': [53], '9': [54, 193], 'Yongqian': [60], 'Shu': [61], '10': [63, 68, 208], 'Ping': [65, 233], 'Liu': [66], 'Department': [70, 85, 101, 120, 131, 147, 162, 177, 194], 'of': [71, 76, 86, 92, 102, 116, 121, 132, 138, 148, 153, 163, 169, 178, 185, 195, 200, 211, 262, 267, 373, 437, 457], 'Oncology,': [72, 104, 164], 'First': [73, 89, 150, 182, 197], 'Affiliated': [74, 90, 135, 151, 167, 183, 198], 'Hospital': [75, 91, 137, 152, 168, 184, 199], 'Nanjing': [77, 80, 93, 96, 108, 126, 139, 142, 154, 157, 186, 189, 201, 204, 212, 215], 'Medical': [78, 94, 140, 155, 187, 202, 213], 'University,': [79, 95, 125, 141, 156, 171, 188, 203, 214], '210029,': [81, 97, 158, 190, 205, 216], 'PR': [82, 98, 110, 128, 144, 159, 174, 191, 206, 217], 'China': [83, 99, 111, 123, 129, 145, 160, 175, 192, 207, 218], '2': [84], 'Thoracic': [87], 'Surgery,': [88], '3': [100], 'Radiation': [103], 'Jiangsu': [105], 'Cancer': [106, 209], 'Hospital,': [107], '210009,': [109, 127], 'State': [113], 'Key': [114], 'Laboratory': [115], 'Natural': [117], 'Medicines': [118], 'and': [119, 180, 328, 349, 376, 382, 394, 420, 429], 'Pharmacognosy,': [122], 'Pharmaceutical': [124], 'Respiration,': [133], 'The': [134, 165, 259, 315, 356], 'Jiangning': [136], '210000,': [143], 'Gastroenterology,': [149], 'Third': [166], 'Soochow': [170], 'Changzhou': [172], '213003,': [173], 'Obstetrics': [179], 'Gynecology,': [181], 'Emergency,': [196], 'Center': [210], 'These': [220], 'authors': [221], 'contributed': [222], 'equally': [223], 'to': [224, 285, 311], 'this': [225], 'work': [226], 'Correspondence': [227], 'to:': [228], 'Zhu,': [230], 'email:': [231, 235], '[email protected]': [232], 'Liu,': [234], '[email protected]': [236], 'Keywords:': [237], 'miRNA,': [238], 'esophageal': [239, 268], 'squamous': [240, 269], 'cell': [241, 270], 'carcinoma,': [242], 'diagnosis,': [243], 'exosomes,': [244], 'TCGA': [245, 414], 'Received:': [246], 'October': [247], '25,': [248], '2016': [249], 'Accepted:': [250], 'March': [251, 255], '15,': [252], '2017': [253, 257], 'Published:': [254], '23,': [256], 'ABSTRACT': [258], 'differential': [260], 'expression': [261], 'microRNAs': [263], '(miRNAs)': [264], 'in': [265, 291, 307, 352, 399, 410, 427, 435, 446, 455], 'plasma': [266, 287, 428, 447], 'carcinoma': [271], '(ESCC)': [272], 'patients': [273, 362], 'may': [274], 'serve': [275], 'as': [276, 433, 451], 'a': [277, 443, 452], 'diagnostic': [278], 'biomarker.': [279], 'A': [280, 339], 'four-stage': [281], 'study': [282], 'was': [283, 354, 407], 'conducted': [284], 'identify': [286], 'miRNAs': [288, 317], 'with': [289, 336, 365, 402, 425], 'potential': [290], 'detecting': [292], 'ESCC.': [293, 438, 458], 'Exiqon': [294], 'panels': [295], '(2': [296], 'ESCC': [297, 324, 332, 353, 361, 388, 411], 'pools': [298], 'vs.': [299], 'normal': [301], 'control': [302], '(NC)': [303], 'pool)': [304], 'were': [305, 318, 396, 422], 'applied': [306], 'the': [308, 368, 379, 383], 'screening': [309], 'phase': [310], 'obtain': [312], 'miRNA': [313], 'profiles.': [314], 'identified': [316, 442], 'further': [319], 'evaluated': [320], 'through': [321], 'training': [322], '(36': [323], 'VS.': [325, 333, 389], '42': [326], 'NCs)': [327, 335], 'testing': [329, 381], 'stages': [330], '(101': [331], '113': [334], 'qRT-PCR': [337, 403], 'assays.': [338, 404], 'six-miRNA': [340, 444], 'signature': [341, 357, 445], 'including': [342], 'up-regulated': [343, 398, 409], 'miR-106a,': [344], 'miR-18a,': [345], 'miR-20b,': [346], 'miR-486-5p,': [347], 'miR-584': [348, 395, 406, 421], 'down-regulated': [350], 'miR-223-3p': [351, 419], 'identified.': [355], 'could': [358, 430, 449], 'accurately': [359], 'discriminate': [360], 'from': [363, 413], 'NCs': [364], 'areas': [366], 'under': [367], 'receiver': [369], 'operating': [370], 'characteristic': [371], 'curve': [372], '0.935,': [374], '0.959': [375], '0.966': [377], 'for': [378], 'training,': [380], 'additional': [384], 'validation': [385], 'stage': [386], '(41': [387], '50': [390], 'NCs),': [391], 'respectively.': [392], 'MiR-106a': [393], 'significantly': [397], 'tumor': [400], 'tissues': [401, 412], 'And': [405], 'also': [408, 431], 'database.': [415], 'In': [416, 439], 'addition,': [417], 'exosomal': [418], 'consistently': [423], 'dysregulated': [424], 'those': [426], 'act': [432, 450], 'biomarkers': [434], 'diagnosis': [436], 'conclusion,': [440], 'we': [441], 'which': [448], 'non-invasive': [453], 'biomarker': [454], 'detection': [456]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2597438135', 'counts_by_year': [{'year': 2024, 'cited_by_count': 5}, {'year': 2023, 'cited_by_count': 6}, {'year': 2022, 'cited_by_count': 5}, {'year': 2021, 'cited_by_count': 12}, {'year': 2020, 'cited_by_count': 9}, {'year': 2019, 'cited_by_count': 10}, {'year': 2018, 'cited_by_count': 10}, {'year': 2017, 'cited_by_count': 5}], 'updated_date': '2024-09-11T20:21:46.922290', 'created_date': '2017-04-07'}