2011 ASA/ACCF/AHA/AANN/AANS/ACR/ASNR/CNS/SAIP/SCAI/SIR/SNIS/SVM/SVS Guideline on the Management of Patients With Extracranial Carotid and Vertebral Artery Disease: Executive Summary

Name: Work Video:
Duration: 3 min 30 s
Thomas G. Brott; Jonathan L. Halperin; Suhny Abbara; J. Michael Bacharach; John D. Barr; Ruth L. Bush; Christopher U. Cates; Mark A. Creager; Susan B. Fowler; Gary Friday; Vicki Hertzberg; E. Bruce McIff; Wesley S. Moore; Peter D. Panagos; Thomas S. Riles; Robert H. Rosenwasser; Allen J. Taylor
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1492, 1493, 1494, 1495, 1496, 1497, 1503, 1504, 1505, 1506, 1510, 1511, 1512, 1513, 1514, 1515, 1516, 1517, 1518, 1519, 1520, 1521, 1522, 1523, 1524, 1525, 1526, 1527, 1528, 1529, 1538, 1539, 1540, 1541, 1542, 1543, 1544, 1545, 1546, 1547, 1548, 1549, 1550, 1551, 1552, 1553, 1554, 1555, 1556, 1557, 1564, 1565, 1566, 1567, 1568, 1569, 1570, 1571, 1572, 1573, 1574, 1575, 1576, 1577, 1578, 1579, 1580, 1581, 1582, 1583, 1584, 1585, 1586, 1587, 1588, 1589, 1590, 1591, 1592, 1602, 1603, 1604, 1605, 1606, 1607, 1616, 1617, 1618, 1619, 1620, 1621, 1622, 1623, 1624, 1625, 1626, 1627, 1628, 1629, 1630, 1631, 1632, 1633, 1634, 1635, 1636, 1637, 1638, 1648, 1649, 1650, 1651, 1652, 1653, 1654, 1655, 1656, 1657, 1658, 1659, 1660, 1661, 1662, 1663, 1664, 1665, 1666, 1667, 1668, 1669, 1670, 1675, 1676, 1677, 1678, 1679, 1680, 1681, 1682, 1690, 1691, 1692, 1693, 1694, 1695, 1696, 1697, 1698, 1699, 1700, 1701, 1702, 1703, 1704, 1705, 1706, 1707, 1708, 1709, 1719, 1720, 1721, 1722, 1723, 1724, 1725, 1726, 1727, 1728, 1729, 1730, 1731, 1732, 1733, 1734, 1737, 1738, 1739, 1740, 1741, 1742, 1743, 1744, 1745, 1746, 1747, 1748, 1749, 1750, 1751, 1752, 1753, 1754, 1755, 1756, 1757, 1758, 1759, 1760, 1775, 1776, 1777, 1778, 1779, 1780, 1781, 1782, 1783, 1784, 1785, 1786, 1787, 1788, 1789, 1790, 1791, 1792, 1793, 1794, 1795, 1796, 1803, 1804, 1805, 1806, 1807, 1808, 1809, 1810, 1811, 1812, 1813, 1814, 1815, 1816, 1817, 1818, 1819, 1820, 1821, 1822, 1823, 1824, 1825, 1826, 1827, 1828, 1829, 1834, 1835, 1836, 1837, 1838, 1839, 1840, 1841, 1842, 1843, 1844, 1845, 1846, 1847, 1848, 1849, 1854, 1855, 1856, 1857, 1858, 1859, 1860, 1861, 1862, 1863, 1864, 1865, 1866, 1867, 1871, 1872, 1873, 1874, 1875, 1876, 1877, 1878, 1879, 1880, 1881, 1882, 1883, 1884, 1885, 1886, 1887, 1888, 1889, 1890, 1891, 1892, 1893, 1894, 1895, 1896, 1897, 1899, 1900, 1901, 1902, 1903, 1904, 1905, 1906, 1907, 1908, 1909, 1910, 1911, 1912, 1913, 1914, 1915, 1916, 1917, 1918, 1919, 1920, 1921, 1922, 1923, 1924, 1925, 1926, 1927, 1928, 1929, 1930, 1931, 1932, 1942, 1943, 1944, 1945, 1946, 1947, 1948, 1949, 1950, 1951, 1952, 1953, 1954, 1955, 1956, 1957, 1958, 1959, 1969, 1970, 1971, 1972, 1973, 1974, 1975, 1976, 1977, 1978, 1979, 1980, 1981, 1982, 1983, 1984, 1985, 1986], '.491': [580], 'Introduction': [581], '.493': [612], '1.1': [613], 'Methodology': [614, 3389], 'Evidence': [616, 2392, 2549, 2649, 2712, 3391], 'Review': [617, 639, 4134], '.4931.2': [626], 'Organization': [627, 3988], 'Writing': [630, 2187, 2239, 3011, 3991, 4209], 'Committee': [631], '.4941.3': [637], 'Document': [638, 4133, 4200], 'Approval': [641], '.494Recommendations': [652, 682], 'Duplex': [654, 4292], 'Ultrasonography': [655, 4293], 'Evaluate': [657, 4295], 'Asymptomatic': [658, 1413, 4296], 'Known': [661, 4299], 'or': [662, 690, 821, 980, 1318, 1472, 2037, 2204, 2256, 2261, 2288, 2370, 2389, 2410, 2437, 2602, 2651, 2679, 2714, 2758, 2762, 2793, 2806, 2902, 3132, 3245, 3350, 3587, 3611, 3633, 3775, 3779, 3785, 4300, 4309, 4383, 4414, 4425, 4459, 4523, 4548, 4596, 4617, 4630, 4633, 4646, 4695, 4710, 4753, 4777, 4786, 4803, 4806, 4815, 4891, 4901], 'Suspected': [663, 4301], 'Stenosis': [665, 1481], 'Diagnostic': [684, 4689], 'Testing': [685, 1284, 4690], 'in': [686, 813, 853, 1004, 1026, 1766, 2022, 2100, 2142, 2147, 2210, 2228, 2314, 2425, 2552, 2611, 2684, 2729, 2911, 2973, 3030, 3040, 3045, 3057, 3111, 3173, 3194, 3208, 3228, 3253, 3289, 3327, 3359, 3433, 3450, 3455, 3568, 3590, 3688, 3696, 3713, 3743, 3783, 3792, 3840, 3900, 3930, 4017, 4243, 4320, 4354, 4375, 4392, 4447, 4488, 4512, 4537, 4691, 4738, 4865, 4886], 'Symptoms': [689, 1264, 4694], 'Signs': [691, 4696], 'Disease': [696, 859, 1009, 1031, 1060, 1196, 1207, 1313, 1509, 1563, 1615, 1647, 1771, 3412, 4012, 4191, 4207, 4214], '.495Recommendations': [709, 775], 'Treatment': [712], 'Hypertension': [714], '.495Recommendation': [744], 'Cessation': [746], 'Tobacco': [748], 'Smoking.': [749], 'Control': [777], 'Hyperlipidemia.': [779], '.496Recommendations': [807, 849, 889], 'Diabetes': [811], 'Mellitus': [812], 'Arteries.': [823, 1689], 'Antithrombotic': [851, 1359], 'Therapy': [852, 1308, 1360, 1641], 'Atherosclerotic': [858, 1023, 1312], 'Not': [860], 'Undergoing': [861, 920, 955, 1772], 'Revascularization': [862, 896, 1090, 1502, 1674, 1712], 'Selection': [891, 1468], '.497Recommendations': [914, 950], 'Periprocedural': [916], 'Endarterectomy.': [922, 1379], 'Stenting.': [958, 1429], '.498Recommendations': [970, 1000, 1019], 'Experiencing': [975], 'Restenosis': [976], 'After': [977], 'Endarterectomy': [979, 1451, 1471], 'Stenting': [981, 1453, 1475], 'Risk': [1024, 1340, 1764], 'Factors': [1025], '.499Recommendations': [1052, 1084, 1121, 1151], 'Occlusive': [1059], 'Subclavian': [1063, 1686, 1717], 'Brachiocephalic': [1065, 1688, 1715], 'Arteries': [1066, 1133, 1214, 1320, 1718], 'Evaluation': [1088, 1609], 'Before': [1091], 'Cardiac': [1092, 1773], 'Fibromuscular': [1127, 1832], 'Dysplasia': [1128, 1833], 'Cervical': [1157, 1851], 'Dissection.': [1159], '.500Cerebrovascular': [1174], 'Arterial': [1175, 1536, 1600, 4206], 'Anatomy': [1176, 1532], '.500': [1190], '19.1': [1191], 'Epidemiology': [1192, 1559], 'Cerebrovascular': [1195], '.500Atherosclerotic': [1206], '.500Clinical': [1231, 1256], 'Presentation.': [1232], 'Assessment': [1257, 1448], 'Focal': [1261], 'Cerebral': [1262], 'Ischemic': [1263], '.501Diagnosis': [1282], '.503Medical': [1307], '.504': [1338], '24.1': [1339], 'Factor': [1341], '.50424.2': [1358], '.50524.3': [1377], '.505': [1396], '24.3.1': [1397], 'Symptomatic': [1398], '.50524.3.2': [1412], '.50624.4': [1426], '.50624.5': [1446], 'Comparative': [1447], '.512': [1466], '24.5.1': [1467], 'Individual': [1477], '.51424.6': [1498], 'Durability': [1499], '.514Vertebral': [1507], '.514': [1530], '25.1': [1531], 'Vertebrobasilar': [1535, 1599], 'Circulation': [1537], '.51425.2': [1558], '.51525.3': [1593], 'Clinical': [1594, 3217], 'Presentation': [1595], 'Insufficiency': [1601], '.51525.4': [1608], '.51525.5': [1639], 'Medical': [1640], '.51525.6': [1671], '.515Diseases': [1683], '.515': [1710], '26.1': [1711], '.516Special': [1735], 'Populations': [1736], '.516': [1761, 1830], '27.1': [1762], 'Reduction': [1765], '.516Nonatherosclerotic': [1797], 'Diseases': [1802], '28.1': [1831], '.51628.2': [1850], 'Dissection': [1853], '.51728.3': [1868], 'Future': [1869], 'Research': [1870], '.517References.': [1898], '.518Appendix': [1933], '1.': [1934], 'Author': [1935], 'Relationships': [1936, 1963], 'Industry': [1938, 1965], 'Other': [1940, 1967], 'Entities': [1941, 1968], '.526Appendix': [1960], '2.': [1961], 'Reviewer': [1962], '.528Jacobs': [1987], 'Alice': [1988], 'K.,': [1989], 'FACC,': [1991, 2002], 'FAHAChair,': [1992], 'ACCF/AHA': [1993, 2006, 2156, 2580, 2952, 3020, 3089, 3102, 3393, 4204], 'GuidelinesSmith': [1998], 'Sidney': [1999], 'C.,': [2000], 'FAHAImmediate': [2003], 'Past': [2004], 'Chair,': [2005], 'GuidelinesPreambleIt': [2011], 'is': [2012, 2092, 2164, 2299, 2422, 2466, 2483, 2550, 2582, 2595, 2722, 2760, 2905, 2985, 3233, 3357, 3372, 3711, 3798, 3838, 3975, 4241, 4324, 4342, 4364, 4479, 4557, 4581, 4607, 4659, 4732, 4791, 4819, 4883], 'essential': [2013], 'that': [2014, 2281, 2338, 2719, 2754, 2779, 2811, 2861, 3036, 3166, 3202, 3261, 3656, 3803, 3842, 4496, 4568, 4868], 'medical': [2016, 2234, 3329, 3525, 3893, 4472], 'profession': [2017], 'play': [2018], 'a': [2019, 2104, 2107, 2246, 2385, 2516, 2583, 2749, 2755, 2815, 2871, 2883, 2895, 3049, 3099, 3117, 3138, 3144, 3182, 3415, 3579, 3689, 3736, 4317, 4321, 4372, 4376, 4534, 4538, 4549, 4561, 4839, 4860], 'central': [2020], 'role': [2021], 'critically': [2023], 'evaluating': [2024], 'evidence': [2026, 2194, 2254, 2347, 2355, 2376, 2421, 3152, 3448, 3660, 3668, 3694, 3710, 3866, 4517], 'related': [2027, 3548, 3614, 3963], 'drugs,': [2029], 'devices,': [2030], 'procedures': [2032, 2061], 'detection,': [2035], 'management,': [2036, 3126], 'prevention': [2038, 3128, 3780, 3856], 'disease.': [2040, 3496], 'Properly': [2041], 'applied,': [2042], 'rigorous,': [2043], 'expert': [2044, 2454, 3141], 'analysis': [2045], 'available': [2048, 2375, 2675, 2986, 3149], 'data': [2049, 2091, 2224, 2271, 2302, 2319, 2362, 2381, 2447, 2513, 3267, 3593, 3613], 'documenting': [2050], 'absolute': [2051, 3603], 'relative': [2053, 3617, 3628, 4540], 'benefits': [2054], 'risks': [2056], 'these': [2058, 2315, 2419, 3212, 3236, 3275, 3292, 3500], 'therapies': [2059, 2289], 'can': [2062, 2102], 'improve': [2063, 3157, 3950, 3977], 'effectiveness': [2065, 2619, 2632, 2765], 'care,': [2067], 'optimize': [2068], 'patient': [2069, 2279, 3024, 3078, 3158, 3184, 3193, 3273, 3304], 'outcomes,': [2070, 3311], 'favorably': [2072], 'affect': [2073, 3310, 4497, 4569], 'cost': [2075, 2298], 'care': [2077, 3180, 3232, 3722, 3831, 3878, 3891, 3903], 'by': [2078, 2334, 2495, 2874, 2882, 2917, 2999, 3115, 3188, 3201, 3338, 3555, 3650, 3663, 4140, 4147, 4173, 4255, 4267, 4316, 4371, 4750, 4774, 4851], 'focusing': [2079], 'resources': [2080], 'effective': [2084, 3295], 'strategies.': [2085], 'One': [2086], 'important': [2087, 2725], 'use': [2088, 2117, 2468, 2782], 'such': [2090, 2112, 2687, 3623, 4465, 4625, 4870], 'production': [2094, 2144], 'clinical': [2096, 2119, 2208, 2306, 2368, 2457, 2486, 2497, 2502, 2677, 2726, 2737, 2752, 3112, 3596, 3830, 3917, 3947, 4498, 4516, 4570, 4593], 'practice': [2097, 2171, 2520, 3021, 3075, 3103, 3135], 'guidelines': [2098, 2146, 2172, 2227, 2731, 3022, 3104, 3136, 3161, 3213, 3237, 3333], 'that,': [2099], 'turn,': [2101], 'provide': [2103, 3576, 3877], 'foundation': [2105], 'variety': [2108], 'other': [2110, 2233, 2822, 2965, 3005, 3314, 3447, 3561, 3912, 4232], 'applications': [2111], 'as': [2113, 2195, 2357, 2377, 2395, 2433, 2461, 2688, 2814, 2836, 2838, 2865, 2937, 3240, 3624, 3907, 3909, 4326, 4626], 'performance': [2114], 'measures,': [2115], 'appropriate': [2116, 2499, 3586], 'criteria,': [2118], 'decision': [2120, 3113, 3218], 'support': [2121, 2780], 'tools,': [2122], 'quality': [2124, 3223, 3254, 3981, 4863], 'improvement': [2125, 3252], 'tools.The': [2126], 'Foundation': [2131], '(ACCF)': [2132], '(AHA)': [2138], 'have': [2139, 2215, 2654, 4397, 4468, 4521, 4591, 4665], 'jointly': [2140], 'engaged': [2141], 'area': [2149, 3230], 'cardiovascular': [2151, 2174, 3896], 'disease': [2152, 3728, 3782, 4386, 4454, 4674, 4677, 4818], 'since': [2153], '1980.': [2154], 'The': [2155, 2342, 2372, 2540, 2990, 3160, 3176, 3257, 3354, 3795, 3861, 3968, 4042, 4282], 'Guidelines': [2161], '(Task': [2162], 'Force)': [2163], 'charged': [2165, 2190, 2243], 'with': [2166, 2191, 2230, 2351, 2604, 2636, 2709, 2819, 2898, 2962, 3291, 3502, 3578, 3638, 3725, 3772, 3817, 3834, 3853, 3881, 3928, 3945, 3986, 4229, 4307, 4357, 4394, 4450, 4615, 4707, 4763, 4888], 'developing,': [2167], 'updating,': [2168], 'revising': [2170], 'diseases': [2175, 3131, 3763], 'procedures,': [2177, 2947], 'directs': [2182], 'oversees': [2184], 'effort.': [2186], 'committees': [2188, 2240], 'assessing': [2192], 'an': [2196, 2563, 4411, 4469, 4878], 'independent': [2197], 'group': [2198], 'authors': [2200], 'develop,': [2202], 'update,': [2203], 'revise': [2205], 'recommendations': [2206, 2313, 2323, 2350, 2450, 2489, 2589, 2628, 2766, 2869, 3293, 3431, 3742], 'practice.Experts': [2209], 'subject': [2212, 3551], 'under': [2213], 'consideration': [2214], 'been': [2216, 2655, 4408], 'selected': [2217, 3565], 'from': [2218, 2232, 2295, 2365, 2384, 2676, 3211, 3352, 3594, 4179], 'both': [2219, 3931], 'organizations': [2220], 'examine': [2222], 'subject-specific': [2223], 'write': [2226], 'partnership': [2229], 'representatives': [2231, 4045], 'practitioner': [2235], 'specialty': [2237], 'groups.': [2238], 'specifically': [2242], 'perform': [2245, 4345], 'formal': [2247], 'literature': [2248, 3420, 3699, 3715], 'review;': [2249], 'weigh': [2250], 'strength': [2252], 'against': [2257], 'particular': [2258, 2756, 3183], 'tests,': [2259], 'treatments,': [2260], 'procedures;': [2262], 'include': [2264, 4719], 'estimates': [2265], 'expected': [2267], 'health': [2268], 'outcomes': [2269, 2307], 'where': [2270, 3231], 'exist.': [2272], 'Patient-specific': [2273], 'modifiers,': [2274], 'comorbidities,': [2275, 3520], 'issues': [2277, 2509], 'preference': [2280], 'may': [2282, 2747, 2812, 2862, 3214, 3308, 4429, 4444], 'influence': [2283], 'choice': [2285], 'tests': [2287], 'considered.': [2291], 'When': [2292, 2488, 3235], 'available,': [2293, 2449, 2515, 2745], 'information': [2294, 2942, 2980, 4225], 'studies': [2296, 2778, 3055], 'considered,': [2300], 'but': [2301, 3461, 4463], 'efficacy': [2304], 'constitute': [2308], 'primary': [2310, 2400, 3535, 3890, 3902], 'basis': [2311, 2530, 3242], 'guidelines.In': [2316], 'analyzing': [2317], 'developing': [2321], 'supporting': [2325, 2348, 3865], 'text,': [2326, 3862], 'writing': [2328, 2526, 2627, 2827, 2834, 2859, 2876, 2890, 2932, 2994, 3067, 3394, 3750, 3993, 4238], 'committee': [2329, 2343, 2373, 2527, 2877, 2891, 2933, 2995, 3012, 3068, 3395, 3545, 3644, 3751, 3994, 4043, 4239], 'used': [2330, 3239, 3599, 3645], 'evidence-based': [2331, 3647], 'methodologies': [2332, 3648], 'developed': [2333, 3649], 'described': [2340], 'elsewhere.1': [2341], 'reviewed': [2344, 2916, 3336, 3546, 4139, 4250], 'ranked': [2346, 2356, 2374, 2394, 2460], 'current': [2349, 2519, 2849, 3150, 3344], 'weight': [2353], 'Level': [2358, 2378, 2396, 2462, 2491, 2532, 2547, 2647, 2663, 2672, 2710, 2771], 'A': [2359, 2575, 2650, 2707, 2774], 'if': [2360, 2506, 3297], 'were': [2363, 2382, 3441, 3462, 3598, 3673], 'derived': [2364, 2383], 'multiple': [2366], 'randomized': [2367, 2387, 2438, 2479, 2741, 3680], 'trials': [2369, 2480, 2678, 2742], 'meta-analyses.': [2371], 'B': [2379, 2652, 2713, 2776], 'when': [2380, 2398, 2439, 3284, 3588, 3642, 3669, 4797], 'single': [2386], 'trial': [2388, 3597], 'nonrandomized': [2390], 'studies.': [2391], 'was': [2393, 2405, 2528, 2996, 3661, 3686, 4013, 4138, 4234, 4249], 'C': [2397, 2492, 2533, 2715], 'source': [2401, 4840, 4880], 'recommendation': [2404, 2594, 2708, 2721], 'consensus': [2406, 2455, 2753, 2884, 3139], 'opinion,': [2407], 'case': [2408], 'studies,': [2409, 2620, 3444], 'standard': [2411], 'care.': [2413, 3159, 3256], 'In': [2414, 2609, 3883], 'narrative': [2416], 'portions': [2417], 'guidelines,': [2420], 'generally': [2423, 3120], 'presented': [2424, 3200], 'chronological': [2426], 'order': [2427], 'development.': [2429], 'Studies': [2430], 'identified': [2432, 3279, 4885], 'observational,': [2434], 'retrospective,': [2435], 'prospective,': [2436], 'appropriate.': [2440, 3216, 4431], 'For': [2441, 2508, 2940, 3054], 'certain': [2442], 'conditions': [2443, 4640], 'which': [2445, 2475, 2511, 2555, 3209, 3265, 3789], 'inadequate': [2446], 'based': [2452, 2484, 3747, 3799], 'experience': [2458], 'C.': [2463], 'An': [2464], 'example': [2465], 'penicillin': [2470], 'pneumococcal': [2472], 'pneumonia,': [2473], 'there': [2476, 2746, 3205], 'no': [2478, 2536, 4592, 4666, 4676], 'treatment': [2482, 2573, 3082, 3288, 3618], 'experience.': [2487], 'at': [2490, 2988, 3787, 3819], 'supported': [2494, 2997], 'historical': [2496], 'data,': [2498, 3583], 'references': [2500, 2537], '(including': [2501], 'reviews)': [2503], 'cited': [2505], 'available.': [2507], 'sparse': [2512], 'survey': [2517], 'among': [2521, 2825], 'clinicians': [2523, 3577, 3875], 'recommendations,': [2534, 3863], 'cited.': [2539], 'schema': [2541], 'Classification': [2543, 2659, 2668], 'Recommendations': [2545, 2661, 2670, 4290, 4687], 'summarized': [2551], 'also': [2556, 3621], 'illustrates': [2557], 'how': [2558], 'grading': [2560], 'system': [2561], 'provides': [2562], 'estimate': [2564], 'size': [2567], 'certainty': [2570], 'effect.': [2574], 'new': [2576, 2896], 'addition': [2577], 'methodology': [2581, 2953], 'separation': [2584], 'Class': [2587, 2641], 'III': [2588], 'delineate': [2591], 'whether': [2592, 3094, 4481, 4559], 'determined': [2596], 'be': [2598, 2748, 2863, 2880, 3186, 3215, 3251, 3278, 3335, 4430, 4445, 4506, 4801, 4834, 4857], '"no': [2600], 'benefit"': [2601], 'associated': [2603], '"harm"': [2605], 'patient.': [2608, 3203], 'addition,': [2610], 'view': [2612], 'increasing': [2615], 'number': [2616, 3607, 3739], 'comparative': [2618, 2631, 2764], 'comparator': [2621, 2784], 'verbs': [2622, 2785], 'suggested': [2624], 'phrases': [2625], 'one': [2634], 'treatment/strategy': [2635], 'respect': [2637], 'another': [2639, 3793], 'Recommendation': [2643], 'I': [2644, 2768], 'IIa,': [2646], 'only': [2653, 3296], 'added.Table': [2656], 'Applying': [2658, 2667], 'EvidenceTable': [2665], 'EvidenceData': [2674], 'registries': [2680], 'about': [2681, 2943], 'usefulness/efficacy': [2683], 'different': [2685, 3074, 3671, 3690, 3820], 'subpopulations,': [2686], 'gender,': [2689], 'age,': [2690], 'history': [2691, 2694, 2699, 4536, 4551], 'diabetes,': [2693], 'prior': [2696, 2704], 'myocardial': [2697], 'infarction,': [2698], 'heart': [2701], 'failure,': [2702], 'aspirin': [2705], 'use.': [2706], 'does': [2716], 'not': [2717, 2733, 2744, 3463, 3574, 3766, 4582, 4608, 4660, 4820, 4884], 'imply': [2718], 'weak.': [2723], 'Many': [2724], 'questions': [2727], 'addressed': [2728], 'do': [2732], 'lend': [2734], 'themselves': [2735, 3764], 'trials.': [2738, 3708], 'Even': [2739], 'though': [2740], 'very': [2750], 'clear': [2751], 'test': [2757, 4330], 'therapy': [2759, 4473], 'useful': [2761], 'effective.†For': [2763], '(Class': [2767], 'IIa;': [2770], 'Evidence:': [2773, 4339, 4362, 4434, 4502, 4574, 4603, 4650, 4685, 4729, 4760, 4812, 4846, 4875], 'only),': [2777], 'should': [2786, 3097, 3220, 3250, 3317, 3949, 4718, 4833, 4856], 'involve': [2787], 'direct': [2788], 'comparisons': [2789], 'treatments': [2792], 'strategies': [2794], 'being': [2795], 'evaluated.The': [2796], 'makes': [2799], 'every': [2800, 3319], 'effort': [2801, 2860, 3320], 'avoid': [2803], 'actual,': [2804], 'potential,': [2805], 'perceived': [2807, 2864], 'conflicts': [2808], 'interest': [2810], 'arise': [2813, 3263], 'result': [2816], 'relationships': [2818, 2850, 2961, 4228], 'industry': [2820, 2899, 2963, 4230], 'entities': [2823, 2966, 4233], '(RWI)': [2824], 'committee.': [2828], 'Specifically,': [2829], 'all': [2830, 2848, 2922, 3197], 'members': [2831, 2887, 2923, 3013, 4178], 'committee,': [2835], 'well': [2837, 3908], 'peer': [2839, 2959], 'reviewers': [2840], 'document,': [2843], 'asked': [2845], 'disclose': [2847], 'those': [2852, 4489], '24': [2853], 'months': [2854], 'before': [2855, 4544], 'initiation': [2856], 'relevant.': [2866], 'All': [2867, 4224], 'guideline': [2868, 2909, 2944, 2970, 3283, 3356, 3797, 3837, 3973], 'require': [2870], 'confidential': [2872], 'vote': [2873], 'must': [2879, 3185], 'approved': [2881, 4252], 'voting.': [2888], 'Any': [2889], 'member': [2892], 'who': [2893, 3876, 3915, 4396, 4520, 4590, 4664, 4740], 'develops': [2894], 'relationship': [2897], 'during': [2900, 2924], 'his': [2901], 'her': [2903], 'tenure': [2904], 'required': [2906], 'notify': [2908], 'staff': [2910], 'writing.': [2912], 'These': [2913, 3134], 'statements': [2914], 'each': [2925, 3066, 3281, 3953, 4148, 4866], 'conference': [2926], 'call': [2927], 'and/or': [2928], 'meeting': [2929], 'updated': [2936], 'changes': [2938], 'occur.': [2939], 'detailed': [2941], 'policies': [2945, 2955], 'please': [2948], 'refer': [2949], 'manual.1': [2956], "Authors'": [2957], "reviewers'": [2960, 4227], 'pertinent': [2967], 'disclosed': [2972], 'Appendixes': [2974], '2,': [2977], 'respectively.': [2978], 'Disclosure': [2979], 'online': [2987], 'www.cardiosource.org/ACC/About-ACC/Leadership/Guidelines-and-Documents-Task-Forces.aspx.': [2989], 'work': [2991], 'exclusively': [2998], 'ACCF': [3001, 3557, 4181, 4184, 4188, 4193], 'AHA': [3003, 3382, 3559, 4211, 4217, 4264], '(and': [3004, 3026, 3560, 3692], 'partnering': [3006, 3562], 'organizations)': [3007], 'without': [3008, 3048, 4490, 4515], 'commercial': [3009], 'support.': [3010], 'volunteered': [3014], 'their': [3015], 'time': [3016], 'effort.The': [3019], 'address': [3023, 3843], 'populations': [3025, 3079, 3786], 'healthcare': [3027, 3109, 3190, 3315, 3913], 'providers)': [3028], 'residing': [3029], 'North': [3031, 3041, 3064], 'America.': [3032], 'As': [3033], 'such,': [3034], 'drugs': [3035], 'currently': [3038], 'unavailable': [3039], 'America': [3042], 'discussed': [3044], 'text': [3047], 'specific': [3050, 3100, 3130, 3810], 'class': [3051], 'recommendation.': [3053], 'performed': [3056, 4315, 4835], 'large': [3058, 3738], 'numbers': [3059], 'subjects': [3061, 3452], 'outside': [3062], 'America,': [3065], 'reviews': [3069], 'potential': [3071], 'impact': [3072], 'patterns': [3076], 'effect': [3083], 'relevance': [3086], 'target': [3090], 'population': [3091], 'determine': [3093], 'findings': [3096, 4849], 'inform': [3098, 3272], 'recommendation.The': [3101], 'intended': [3106, 3155, 3868], 'assist': [3108, 3870], 'providers': [3110, 3316], 'making': [3114, 3219], 'describing': [3116], 'range': [3118], 'acceptable': [3121], 'approaches': [3122], 'diagnosis,': [3125], 'conditions.': [3133], 'represent': [3137], 'opinion': [3142], 'after': [3143], 'thorough': [3145], 'review': [3146, 3417], 'scientific': [3151], 'attempt': [3162], 'define': [3164], 'practices': [3165], 'meet': [3167], 'needs': [3169], 'patients': [3172, 3724, 3771, 3816, 3833, 3852, 3880, 3927, 4306, 4356, 4393, 4449, 4466, 4514, 4589, 4614, 4663, 4706, 4739, 4762, 4887], 'circumstances.': [3175], 'ultimate': [3177, 3969], 'judgment': [3178], 'regarding': [3179], 'made': [3187], 'provider': [3191], 'light': [3195], 'circumstances': [3199], 'Thus,': [3204], 'situations': [3207, 3262], 'deviations': [3210], 'consider': [3221], 'availability': [3225], 'expertise': [3227], 'provided.': [3234], 'regulatory': [3244], 'payer': [3246], 'decisions,': [3247], 'goal': [3249, 3970], 'recognizes': [3260], 'additional': [3266, 4484], 'needed': [3269, 3608], 'better': [3271], 'care;': [3274], 'areas': [3276, 4019], 'will': [3277, 3334, 3805], 'within': [3280], 'respective': [3282], 'appropriate.Prescribed': [3285], 'courses': [3286], 'accordance': [3290], 'they': [3298, 3346, 3885], 'followed.': [3300], 'Because': [3301, 3709], 'lack': [3302], 'understanding': [3305], 'adherence': [3307], 'adversely': [3309], 'physicians': [3312], 'make': [3318], 'engage': [3322], "patient's": [3324, 4416], 'active': [3325], 'participation': [3326], 'prescribed': [3328], 'regimens': [3330], 'lifestyles.The': [3332], 'annually': [3337, 4370], 'considered': [3343, 4446, 4507], 'unless': [3345], 'updated,': [3348], 'revised,': [3349], 'withdrawn': [3351], 'distribution.': [3353], 'full-text': [3355, 3796], 'e-published': [3358], 'Journal': [3361], 'Cardiology,': [3367], 'Circulation,': [3368], 'posted': [3373], '(www.cardiosource.org)': [3380], '(my.americanheart.org)': [3383], 'World': [3384], 'Wide': [3385], 'Web': [3386], 'sites.1.': [3387], 'Introduction1.1.': [3388], 'ReviewThe': [3392], 'create': [3397], '2011': [3399, 3998], '(ECVD)': [3413], 'conducted': [3414, 3449, 3687], 'comprehensive': [3416, 3580], 'relevant': [3421], 'carotid': [3423, 3468, 3471, 3474, 3476, 3478, 3480, 3485, 3510, 3727, 4311, 4335, 4352, 4358, 4442, 4491, 4510, 4657, 4673, 4736, 4756, 4780, 4795, 4853], 'vertebral': [3425, 3494, 3540, 3733], 'artery': [3426, 3469, 3481, 3486, 3495, 3511, 3541, 3734, 4457], 'interventions': [3427, 3672, 4391], 'through': [3428], 'May': [3429], '2010.The': [3430], 'listed': [3432], 'document': [3435, 3570, 3745, 3759, 3808, 4137, 4245, 4248], 'are,': [3436], 'whenever': [3437, 3584], 'possible,': [3438], 'evidence-based.': [3439], 'Searches': [3440], 'limited': [3442, 3464], 'reviews,': [3445], 'human': [3451], 'published': [3454, 3554, 3567, 3589, 4242], 'English.': [3456], 'Key': [3457], 'search': [3458, 3806, 4837], 'words': [3459], 'included': [3460, 4044], 'angioplasty,': [3466], 'atherosclerosis,': [3467, 3522], 'disease,': [3470, 3735, 4458], 'endarterectomy': [3472], '(CEA),': [3473], 'revascularization,': [3475], 'stenosis,': [3477, 3487, 4312], 'stenting,': [3479], 'stenting': [3482], '(CAS),': [3483], 'extracranial': [3484, 3521, 4656, 4814, 4879], 'stroke,': [3488], 'transient': [3489, 4708, 4889], 'ischemic': [3490, 3859, 4476, 4553, 4716, 4766, 4830, 4897], 'attack': [3491], '(TIA),': [3492], 'Additional': [3497], 'searches': [3498], 'cross-referenced': [3499], 'topics': [3501], 'following': [3504, 4527], 'subtopics:': [3505], 'acetylsalicylic': [3506], 'acid,': [3507], 'antiplatelet': [3508], 'therapy,': [3509, 3526, 3532], 'dissection,': [3512], 'cerebral': [3513, 3515, 4623, 4632, 4903], 'embolism,': [3514], 'protection,': [3516], 'cerebrovascular': [3517, 4817], 'disorders,': [3518, 4636, 4645], 'complications,': [3519], 'intima-media': [3523], 'thickness,': [3524], 'neurological': [3527, 4616, 4712, 4743, 4767, 4826, 4893], 'examination,': [3528], 'noninvasive': [3529, 4032, 4720], 'testing,': [3530], 'pharmacological': [3531], 'preoperative': [3533], 'risk,': [3534, 3629, 3788], 'closure,': [3536], 'risk': [3537, 3604, 4528, 4597, 4667], 'factors,': [3538], 'dissection.': [3542], 'Additionally,': [3543], 'documents': [3547], 'matter': [3552], 'previously': [3553], 'organizations).': [3563], 'References': [3564], 'representative': [3572], 'all-inclusive.To': [3575], 'set': [3581], 'deemed': [3585], 'article,': [3592], 'calculate': [3601], 'difference': [3605], 'treat': [3610], 'harm;': [3612], 'effects': [3619], 'provided,': [3622], 'odds': [3625], 'ratio': [3626, 3631], '(OR),': [3627], 'hazard': [3630], '(HR),': [3632], 'incidence': [3634], 'rate': [3635], 'ratio,': [3636], 'along': [3637], 'confidence': [3639], 'intervals': [3640, 4424], '(CIs)': [3641], 'available.The': [3643], 'acknowledges': [3655], 'adjudication': [3657], 'complicated': [3662], 'timing': [3665], '2': [3670, 4522], 'contrasted.': [3674], 'Despite': [3675], 'similar': [3676], 'study': [3677], 'designs': [3678], '(eg,': [3679], 'controlled': [3681], 'trials),': [3682], 'research': [3683], 'CEA': [3685], 'era': [3691], 'thus,': [3693], 'existed': [3695], 'peer-reviewed': [3698], 'more': [3701, 3705, 4524], 'time)': [3702], 'than': [3703, 4401], 'contemporary': [3706], 'CAS': [3707], 'lacking': [3712], 'guide': [3717], 'many': [3718], 'aspects': [3719], 'nonatherosclerotic': [3726], 'forms': [3731], 'relatively': [3737], 'consensus.The': [3749], 'chose': [3752], 'limit': [3754], 'scope': [3756], 'vascular': [3762, 3905, 4026, 4036, 4681], 'management': [3769, 3814, 3850, 3925], 'acute': [3773], 'stroke': [3774, 3961], 'detection': [3778, 4724], 'individuals': [3784, 4145], 'covered': [3791], 'guideline.2': [3794], 'presumption': [3802], 'readers': [3804], 'advice': [3811], 'ECVD': [3818, 3929, 4487, 4564], 'phases': [3821], 'illness.': [3823], 'Following': [3824], 'typical': [3826], 'chronology': [3827], 'ECVD,': [3835, 3854], 'organized': [3839], 'sections': [3841], 'pathogenesis,': [3845], 'epidemiology,': [3846, 4039], 'diagnostic': [3847, 3940, 4329, 4871], 'evaluation,': [3848], 'including': [3855, 4144, 4177], 'recurrent': [3858], 'events.': [3860], 'diverse': [3872], 'array': [3873], 'ECVD.': [3882, 4726], 'particular,': [3884], 'designed': [3887], 'aid': [3889], 'clinicians,': [3892], 'surgical': [3895], 'specialists,': [3897], 'trainees': [3899], 'specialties,': [3906], 'nurses': [3910], 'personnel': [3914], 'seek': [3916], 'tools': [3918], 'promote': [3920], 'proper': [3922], 'evaluation': [3923, 4612, 4704], 'inpatient': [3932], 'outpatient': [3934], 'settings.': [3935], 'Application': [3936], 'recommended': [3939, 4325, 4583, 4609, 4661, 4733], 'therapeutic': [3942, 4390], 'strategies,': [3943], 'combined': [3944], 'careful': [3946], 'judgment,': [3948], 'diagnosis': [3951, 4485, 4562], 'syndrome,': [3954], 'enhance': [3955], 'prevention,': [3956], 'decrease': [3958], 'rates': [3959], 'long-term': [3964], 'disability': [3965], 'death.': [3967], 'statement': [3974], 'duration': [3979], 'life': [3983], 'people': [3985], 'ECVD.1.2.': [3987], 'CommitteeThe': [3992], 'develop': [3996, 4741], 'composed': [4014], 'experts': [4016], 'medicine,': [4021, 4035, 4037], 'surgery,': [4022, 4027], 'neurology,': [4023], 'cardiology,': [4024], 'radiology,': [4025, 4031], 'neurosurgery,': [4028], 'neuroradiology,': [4029], 'interventional': [4030], 'imaging,': [4033], 'emergency': [4034], 'nursing,': [4038], 'biostatistics.': [4041], '(ASA),': [4051], 'ACCF,': [4052, 4152, 4262], 'AHA,': [4053, 4153], 'Academy': [4055], 'Neurology': [4057], '(AAN),': [4058], 'Nurses': [4063], '(AANN),': [4064], 'Surgeons': [4069, 4090], '(AANS),': [4070], 'Emergency': [4074], 'Physicians': [4075], '(ACEP),': [4076], 'Radiology': [4080, 4115], '(ACR),': [4081], 'Neuroradiology': [4085], '(ASNR),': [4086], '(CNS),': [4091], 'Prevention': [4097], '(SAIP),': [4098], 'Interventions': [4104], '(SCAI),': [4105], 'Computed': [4109], 'Tomography': [4110], '(SCCT),': [4111], '(SIR),': [4116], '(SNIS),': [4121], 'Medicine': [4125], '(SVM),': [4126], '(SVS).1.3.': [4132], 'ApprovalThe': [4136], '55': [4141], 'external': [4142], 'reviewers,': [4143, 4176], 'nominated': [4146], 'ASA,': [4151, 4261], 'AANN,': [4154, 4269], 'AANS,': [4155, 4270], 'ACEP,': [4156], 'Physicians,': [4160], 'ACR,': [4161, 4271], 'ASNR,': [4162, 4272], 'CNS,': [4163, 4273], 'SAIP,': [4164, 4274], 'SCAI,': [4165, 4275], 'SCCT,': [4166, 4276], 'SIR,': [4167, 4277], 'SNIS,': [4168, 4278], 'SVM,': [4169, 4279], 'SVS,': [4171], 'individual': [4174, 4222], 'content': [4175], 'Catheterization': [4182], 'Committee,': [4183, 4192, 4210, 4216, 4220], 'Scientific': [4186, 4195], 'Council,': [4187, 4196], 'Peripheral': [4189, 4205, 4212], "Surgeons'": [4194], 'ACCF/SCAI/SVMB/SIR/ASITN': [4197], 'Expert': [4198], 'Consensus': [4199], 'Stenting,': [4203], 'Steering': [4215], 'Leadership': [4219], 'nominees.': [4223], 'distributed': [4235], '(Appendix': [4246], '2).This': [4247], 'publication': [4254], 'governing': [4257], 'bodies': [4258], 'endorsed': [4266], 'SVS.': [4281], 'AAN': [4283], 'affirms': [4284], 'value': [4286], 'guideline.2.': [4289], 'StenosisClass': [4303], 'IIn': [4304], 'asymptomatic': [4305, 4355, 4448, 4513, 4588], 'known': [4308], 'suspected': [4310, 4829, 4896], 'duplex': [4313, 4346, 4368, 4579, 4605], 'ultrasonography,': [4314], 'qualified': [4318, 4373], 'technologist': [4319, 4374], 'certified': [4322, 4377], 'laboratory,': [4323], 'initial': [4328, 4680, 4703], 'detect': [4332, 4349, 4439, 4509, 4735, 4794], 'hemodynamically': [4333, 4350, 4440], 'significant': [4334, 4351, 4441], 'stenosis.': [4336], '(Level': [4337, 4360, 4432, 4500, 4572, 4601, 4648, 4683, 4727, 4758, 4810, 4844, 4873], 'C)Class': [4340, 4435, 4575, 4876], 'IIaIt': [4341], 'reasonable': [4343, 4365], 'ultrasonography': [4347, 4369, 4437, 4504, 4580, 4606, 4731], 'stenosis': 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