Title: Methylenetetrahydrofolate reductase (MTHFR): Mythology or polymorphism(ology)?
Abstract: Nutrients can act as dietary signals, influencing genes, and protein expression and, subsequently, metabolite production. The diversity in the individual genetic profile affects nutrient requirements, metabolism, and responses to dietary interventions.Humans have developed the ability to extract and combine food nutrients, altering the way they naturally exist and unbalancing the composition of food. Therefore, nutrition is not anymore “a way to fuel the body” but rather something much more complex and deeply entangled with the specific genetic features. Nutrigenomics emerges as the science that provides a molecular genetic understanding on how common dietary chemicals affect health.The interaction between genes and dietary chemicals, namely polyphenols, is the main objective of this chapter as well as the major progresses in polyphenols–gene interaction of specific food groups. The recent international initiatives related with nutrigenomics and the developing personalized nutrition are also presented and discussed.
Publication Year: 2016
Publication Date: 2016-12-01
Language: en
Type: article
Indexed In: ['crossref']
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Cited By Count: 6
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