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1235, 1772, 1828, 2101, 2460], 'involves': [249], 'splitting': [250], 'layers': [253], 'aortic': [256, 295, 326, 538, 611, 618, 723, 798, 849, 871, 1019, 1034, 1164, 1219, 1542, 1827, 1965, 2459], 'wall,': [257], 'systemic': [259, 532, 1037, 1774], 'hypertension': [260, 737, 759], 'a': [262, 283, 312, 319, 322, 337, 531, 707, 715, 753, 761, 773, 777, 791, 822, 882, 943, 977, 1027, 1046, 1167, 1194, 1241, 1280, 1642, 1735, 1738, 1821, 2056, 2313], 'major': [263], 'predisposing': [264], 'risk': [265, 796, 820, 1017, 1032, 1963], 'factor.': [266], 'often': [270], 'fatal': [271], 'unless': [272], 'it': [273], 'diagnosed': [275], 'early': [276], 'aggressive': [278], 'treatment': [279, 416, 2457], 'initiated': [281], 'timely': [284], 'manner.': [285], 'Although': [286], 'have': [288], 'been': [289, 410], 'suspected': [290], 'onset': [293, 642], 'anecdotal': [298], 'case': [299, 1242, 1727], 'reports,': [300], 'no': [301, 906, 920, 1101], 'comparative': [302, 338], 'study': [303, 339], 'has': [304], 'assessed': [305], 'link.': [307], 'Using': [308, 1641], 'disproportionality': [309], 'analysis1': [310], 'large': [313, 883], 'postmarketing': [315], 'database,': [316, 2280], 'we': [317, 335, 751, 789, 991], 'detected': [318], 'signal': [320, 333, 792, 805, 978, 1028, 1141], 'potential': [323, 831, 1822], 'association': [324, 867, 879], 'between': [325, 391, 868], 'VPIs.': [329, 1040], 'To': [330], 'examine': [331], 'further,': [334], 'performed': [336, 752], 'within': [340], 'database.The': [342], '(JADER)': [348], 'database': [349, 377, 884, 897], 'was': [350, 368, 631, 643, 701, 739, 806, 919], 'obtained': [351], 'from': [352, 1055, 1070, 1082, 2168], 'webpage': [354], 'Pharmaceuticals': [357], 'Devices': [360], 'Agency': [361], '(PMDA)': [362], '(https://www.pmda.go.jp/).': [363], 'Institutional': [364], 'review': [365, 1781], 'board': [366], 'approval': [367], 'not': [369, 601, 913, 949, 960, 993], 'required': [370], 'because': [371, 718], 'JADER': [372], 'an': [374, 469, 494, 597, 794, 866, 902, 915, 980, 1015, 1030, 1825, 2176], 'unlinkable': [375], 'anonymized': [376], 'open': [378], 'public.': [381], 'We': [382], 'extracted': [383], 'spontaneous': [384, 1146], 'adverse': [385, 1150], 'drug': [386, 1151], 'reaction': [387], '(ADR)': [388], 'reports': [389, 864, 947, 1052, 1068], 'published': [390, 846, 1793], 'April': [392], '2004': [393], 'October': [395, 405], '2015': [396], 'associated': [398, 552, 1672, 2063, 2307], 'systemically': [400], 'administered': [401], 'drugs.': [402, 971], 'As': [403], '2015,': [406], '8': [407, 432, 2482], 'had': [409, 537, 730, 760, 776, 856], 'approved': [411, 433, 495], 'malignant': [419, 523, 599], 'tumors,': [420], 'including': [421, 484, 811, 963, 1021], 'renal': [422, 1201, 1745], 'cell': [423, 1202, 1746], 'carcinoma,': [424, 426, 1747, 2073, 2466], 'hepatocellular': [425, 2072, 2465], 'soft': [428], 'tissue': [429], 'sarcomas.': [430], 'are': [435, 888, 948, 959], 'ramucirumab,': [439], 'lenvatinib,': [440, 570], 'vandetanib,': [441], 'axitinib,': [442], 'pazopanib.': [444], 'Subjects': [445], 'at': [448, 478, 1105], 'least': [449, 479], '1': [450, 480], 'these': [452, 1004], 'were': [454, 504, 528, 551, 584], 'defined': [455], 'VPI': [458, 728, 743, 774, 801, 852], 'group,': [459], 'whereas': [460, 534], 'reference': [462, 629, 748], 'group': [463, 622, 630, 729, 744], 'comprised': [464], 'subjects': [465, 520, 595], 'cancer(s)': [467], 'underlying': [470, 522, 598, 967], 'disease,': [471], 'well': [473], 'those': [475, 910, 1022], 'antimalignant': [481], 'neoplasm': [482, 600], 'agent,': [483], 'tyrosine': [485, 1816, 2068], 'kinase': [486, 1817, 1954, 2069, 2170], 'inhibitors,': [487, 2319], 'monoclonal': [488], 'antibodies,': [489], 'other': [491, 1098], 'drugs': [492], 'indication': [496], 'any': [498], 'kind': [499], 'cancer.': [501], 'data': [503, 954], 'analyzed': [505], 'R': [507, 511, 1586, 1850, 2164, 2226], 'software': [508], '(version': [509], '3.1.2;': [510], 'Development': [512, 2054], 'Core': [513], 'Team,': [514], 'Vienna,': [515], 'Austria).Of': [516], '91': [518], '055': [519], 'neoplasms,': [524], '16': [525], '441': [526], '(18.1%)': [527], 'VPI,': [533, 689], '59': [535, 542], '(0.065%)': [536], 'dissection.': [539, 612], 'Of': [540, 591], 'cases,': [543], '49': [544, 722], '[0.30%': [545], '(95%': [546, 607, 633, 768, 784], 'confidence': [547, 686], 'interval': [548], '[CI],': [549], '0.22–0.39)]': [550], 'use': [555, 771, 1675], '(sunitinib,': [558], 'n': [559, 563, 567, 571, 575, 580], '=': [560, 564, 568, 572, 576, 581], '14;': [561], '11;': [565], '21;': [569], '1;': [573, 577], 'axitinib': [574], 'pazopanib': [579], '3;': [582], '2': [583, 854, 860], 'both': [587], 'sunitinib': [588, 1198], 'pazopanib).': [590], '74': [593], '614': [594], 'VPIs,': [604, 810], '10': [605], '[0.01%': [606], 'CI,': [608, 634, 769, 785], '0.01–0.02)]': [609], 'developed': [610], 'crude': [614, 696], 'odds': [615, 697, 764, 780], 'ratio': [616, 698, 765, 781], 'relative': [626], '22.3': [632, 699], '11.2–49.4)': [635], '(Table': [636], '1).': [637], 'median': [639], 'time': [640], '105': [644], 'days': [645], '(range:': [646], '4–1363': [647], 'days).Table': [648], '1.': [649], 'Proportion': [650], 'Odds': [652], 'Ratio': [653], 'CaseDrugNumber': [657], 'CaseNumber': [661], 'SubjectsProportion': [663], 'DissectionOdds': [666], 'RatioPoint': [667], 'Estimate': [668], '(%)95%': [669], 'CIPoint': [670], 'Estimate95%': [671], 'CIVPI4916': [672], '4410.30[0.22–0.39]22.3*[11.2–49.4]': [673], 'Sunitinib1430100.47[0.25–0.78]34.9[14.4–87.8]': [674], 'Sorafenib1149750.22[0.11–0.40]16.5[6.4–43.4]': [675], 'Bevacizumab2174280.28[0.18–0.43]21.1[9.5–50.4]': [676], 'Ramucirumab02260.00[0.00–1.62]': [677], 'Lenvatinib1961.04[0.03–5.67]78.5[1.8–566.3]': [678], 'Vandetanib090.00[0.00–33.63]': [679], 'Axitinib14400.23[0.01–1.26]17.0[0.4–120.3]': [680], 'Pazopanib26890.44[0.09–1.27]32.6[5.8–127.3]Other': [681], 'than': [682, 745], 'VPI1074': [683], '6140.01[0.01–0.02]ReferenceCI': [684], 'indicates': [685], 'interval;': [687], 'inhibitor.*The': [695], '[11.2–49.4]': [700], '19.4': [702, 783], '[10.2–40.8]': [703], 'when': [704], 'adjusted': [705, 763, 779], 'medical': [708, 1538], 'history': [709], 'hypertension.Hypertension': [711], 'appeared': [712], 'be': [714, 930, 985, 1010, 1045], 'confounding': [716, 957], '25': [719], 'cases': [725, 738, 847, 900, 1783], 'baseline': [731], 'hypertension,': [732], 'percentage': [735], 'higher': [740], 'group.': [749], 'When': [750], 'multivariate': [754], 'logistic': [755], 'regression': [756], 'analysis,': [757, 1968], 'although': [758, 1006], 'high': [762, 778], '3.8': [767], '2.3–6.4),': [770], 'still': [775], '10.2–40.8).In': [786], 'study,': [788], 'found': [790, 922, 1026], 'increased': [795, 834, 981, 1016, 1031], 'after': [800, 2102], 'treatment.': [802], 'Because': [803, 895, 938], 'seen': [807], 'several': [809], 'suggests': [817], 'that': [818, 995], 'class': [823, 1047], 'effect.': [824], 'mechanisms': [826], 'could': [827, 928], 'include': [828], 'known': [830, 1830], 'induce': [833], 'blood': [835, 2304], 'pressure': [836, 2305], 'suppress': [838], 'healing': [840], 'damaged': [842], 'endothelium.Of': [843], '4': [845], 'during': [851, 1036, 1221, 1236, 1335, 2461], 'treatment,': [853], 'patients': [855, 1013], 'preexisting': [857], 'hypertension2,3': [858], 'did': [861, 912], 'not.4,5': [862], 'These': [863], 'implied': [865], 'dissection,': [872, 1020], 'current': [875, 1537], 'report': [876, 1100], 'reinforces': [877], 'based': [880, 1002], 'on': [881, 909, 923, 955, 1003, 1737, 2315, 2322], 'ADR': [886, 893, 946], 'reports.There': [887], 'limitations': [889], 'database.': [894], 'registers': [898], 'only': [899, 976], 'ADR,': [903], 'there': [904, 918], 'information': [907, 921], 'available': [908, 1104], 'who': [911], 'ADR.': [916], 'Consequently,': [917, 990], 'drug-exposed': [925], 'population.': [926], 'There': [927], 'also': [929], 'reporting': [931, 1147], 'bias': [932], 'noise': [934], 'data.': [937], 'lack': [941], 'research': [944], 'protocol,': [945], 'collected': [950, 961], 'systematically.': [951], 'In': [952], 'addition,': [953], 'possible': [956], 'factors': [958], 'systematically,': [962], 'patient': [964, 1169, 1195, 1736], 'background': [965], 'information,': [966], 'conditions,': [968], 'concomitant': [970], 'Therefore,': [972], 'our': [973], 'results': [974], 'show': [975], 'risk,': [982], 'which': [983], 'must': [984], 'confirmed': [986], 'further': [988], 'evaluations.': [989], 'do': [992, 1332], 'recommend': [994], 'clinicians': [996], 'alter': [997], 'prescription': [999], 'results,': [1005], 'appropriate': [1007], 'monitoring': [1008], 'should': [1009], 'considered': [1011], 'hypertension.Our': [1024], 'analysis': [1025], 'exposure': [1038], 'This': [1041], 'finding': [1042], 'appears': [1043], 'effect.Sources': [1048], 'FundingNone.DisclosuresDr': [1050], 'personal': [1053, 1080], 'fees': [1054, 1081], 'Novartis': [1056], 'Pharma': [1057], 'K.K.': [1058], 'Sanofi': [1060], 'K.K.,': [1061], 'outside': [1062, 1093], 'submitted': [1064, 1095], 'work.': [1065, 1096], 'Dr': [1066], 'grants': [1069], 'Bristol-Myers,': [1071], 'Pfizer,': [1072], 'Chugai': [1073], 'Pharmaceutical,': [1074, 1084, 1086, 1090], 'Daiichi': [1075], 'Sankyo,': [1076], 'Sumitomo': [1078], 'Dainippon-pharma;': [1079], 'Taiho': [1083], 'Rohto': [1085], 'Celgene,': [1087], 'Novartis,': [1088], 'Ohtsuka': [1089], 'Sysmex,': [1092], 'authors': [1099], 'conflicts.FootnotesCirculation': [1102], 'http://circ.ahajournals.org.Correspondence': [1106], 'to:': [1107], '4-6-1': [1121], 'Shirokanedai,': [1122], 'Minato-ku,': [1123], 'Tokyo-to,': [1124], '108–8639': [1125], 'Japan.': [1126], 'E-mail': [1127], '[email': [1128], 'protected]References1.': [1129], 'van': [1130, 1135], 'Puijenbroek': [1131], 'E,': [1132, 1262, 1357, 1393, 1407, 1415, 1431, 1466, 1474], 'Diemont': [1133], 'W,': [1134, 1318, 2398], 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'FiguresReferencesRelatedDetailsCited': [1257], 'By': [1258], 'Ahmed': [1259], 'T,': [1260, 1375, 1391, 1433, 1516, 1695, 2029, 2035, 2394, 2396, 2400], 'Mouhayar': [1261], 'Banchs': [1263], 'Karimzad': [1265], 'K,': [1266, 1298, 1310, 1363, 1435, 1456, 1462, 1944, 2031, 2045, 2159, 2404, 2449], 'Hassan': [1267], 'S,': [1268, 1312, 1395, 1454, 1472, 1488, 1510, 1522, 1604, 1758, 1762, 1908, 1946, 1999, 2143, 2145, 2262], 'Brewster': [1269], 'A': [1270, 1325, 1544, 1638, 1721, 1726, 1780, 1890, 1914, 1951, 2005, 2267, 2298, 2361], 'Yusuf': [1272], 'S': [1273, 2454], '(2022)': [1274, 1532, 1567, 1590], 'Extensive': [1275], 'Painless': [1276], 'Patient': [1281], 'With': [1282, 2246], 'Breast': [1283], 'Cancer,': [1284], 'Current': [1285, 1573], 'Problems': [1286], 'Cardiology,': [1288], '10.1016/j.cpcardiol.2022.101253,': [1289], '(101253),': [1290], 'Online': [1291, 1343, 1556, 1581, 1653, 1686, 1802, 1841, 1899, 1937, 1975, 1992, 2024, 2081, 2113, 2185, 2255, 2285, 2328, 2372, 2436, 2473], 'publication': [1292, 1344, 1557, 1582, 1654, 1687, 1803, 1842, 1900, 1938, 1976, 1993, 2025, 2082, 2114, 2186, 2256, 2286, 2329, 2373, 2437, 2474], 'date:': [1293, 1345, 1558, 1583, 1655, 1688, 1804, 1843, 1901, 1939, 1977, 1994, 2026, 2083, 2115, 2187, 2257, 2287, 2330, 2374, 2438, 2475], '1-May-2022.': [1294], 'Rose': [1295], 'A,': [1296, 1304, 1379, 1419, 1437, 1478, 1482, 1484, 1490, 1494, 1496, 1561, 1756, 1848, 1868, 1906, 1912, 2092, 2155, 2212, 2292, 2294, 2339, 2441], 'Kobus': [1297], 'Bohmann': [1299], 'Trenner': [1301], 'M,': [1302, 1351, 1353, 1359, 1369, 1381, 1383, 1389, 1427, 1445, 1450, 1452, 1458, 1464, 1480, 1500, 1524, 1606, 1612, 1691, 1754, 1760, 1942, 2047, 2202, 2214, 2296, 2392, 2443], 'Wahida': [1303], 'Eckstein': [1305], 'H,': [1306, 1468, 1492, 2135, 2151], 'Bassermann': [1307], 'F,': [1308, 1403, 2088, 2194], 'Heckel': [1309], 'Wolk': [1311], 'Reeps': [1313], 'Schwaiger': [1315], 'Eilenberg': [1317], 'Neumayer': [1319], 'Burghuber': [1321], 'C': [1322, 2351], 'Busch': [1324], '(2021)': [1326, 1624, 1668, 1701, 1725, 1768, 1811, 1854, 1882, 1918, 1952], 'Concomitantly': [1327], 'discovered': [1328], 'visceral': [1329], 'artery': [1330, 1730, 2062], 'aneurysms': [1331], 'rarely': [1333], 'grow': [1334], 'therapy,': [1337], 'Clinical': [1338, 1681, 2074, 2467], 'Anatomy,': [1339], '10.1002/ca.23813,': [1340], '35:3,': [1341], '(296-304),': [1342], '1-Apr-2022.': [1346], 'Pena': [1347, 1400], 'R,': [1348, 1371, 1401, 1425, 1476, 1662, 1872, 2033, 2041, 2196, 2206], 'Hofmann': [1349], 'Bowman': [1350, 1463], 'Ahmad': [1352, 1499], 'Pham': [1354, 1517], 'Kline-Rogers': [1356, 1465], 'Case': [1358, 1836, 2468], 'Lee': [1360, 1511, 2142], 'Eagle': [1362, 1461], 'Cotter': [1364], 'N,': [1365, 1413, 2001, 2039, 2043, 2139, 2147, 2200, 2447], 'David': [1366], 'Fasano': [1368], 'Goldenberg': [1370], 'Howitt': [1372], 'Söderlund': [1374], 'Trotter': [1376], 'D,': [1377, 1443, 1486, 1719, 1870, 1874, 2086, 2137, 2157, 2343], 'Rabin': [1378], 'Boehler-Tatman': [1380], 'Russo': [1382], 'Drudi': [1384], 'L,': [1385, 1387, 1399, 1411, 1423, 1448, 1508, 1526, 1610, 2003, 2198, 2337], 'Marks': [1386], 'Yousif': [1388], 'Hoffstaetter': [1390], 'Taubenfeld': [1392], 'Vemulapalli': [1394], 'Campos': [1396], 'Rusche': [1398], 'Mussa': [1402], 'MacCarrick': [1404], 'G,': [1405, 1439, 1441, 1660, 2133, 2290], 'Goldsborough': [1406], 'Samuel': [1408], 'Xu': [1410], 'Mouawad': [1412], 'Yassa': [1414], 'Teng': [1416], 'X,': [1417, 1608, 1910], 'Politano': [1418], 'Teindl': [1420], 'Bloom': [1422], 'Gluck': [1424], "O'Neal": [1426], 'Grima': [1428], 'Masciale': [1430], 'Ota': [1432], 'Wright': [1434], 'Hakim': [1436], 'Owens': [1438], 'Arnaoutakis': [1440], 'Judelson': [1442], "D'Oria": [1444], 'del': [1446], 'Rio-Sola': [1447], 'Ajalat': [1449], 'Chau': [1451], 'Talutis': [1453], 'Woo': [1455], 'Wohlauer': [1457], 'Yi': [1459], 'Kim': [1467], 'Henoud': [1469], 'Damrauer': [1471], 'Krol': [1473], 'Afifi': [1475], 'Cecchi': [1477], 'Drake': [1479], 'Estrera': [1481], 'Hebert': [1483], 'Milewicz': [1485, 2156], 'Prakash': [1487], 'Roberts': [1489], 'Sandhu': [1491], 'Smith-Washington': [1493], 'Tanaka': [1495], 'Watson': [1497], 'Albright': [1501], 'Burke': [1503], 'Byers': [1505], 'P,': [1506, 2345], 'Kennedy': [1507], 'Lawrence': [1509], 'Medina': [1513], 'Nishath': [1515], 'Segal': [1519], 'Shalhub': [1521], 'Soto': [1523], 'Catalan': [1525], 'Patterson': [1527], 'M': [1528, 1697, 1724, 1878, 2049, 2095, 2118, 2377, 2406, 2409], 'Ilonzo': [1530], 'N': [1531, 2354], 'An': [1533, 1706], 'assessment': [1534], 'management': [1539], 'thoracic': [1541], 'disease:': [1543], 'patient-centered': [1545], 'scoping': [1546], 'literature': [1547], 'review,': [1548], 'Seminars': [1549], 'Surgery,': [1552], '10.1053/j.semvascsurg.2022.02.007,': [1553], '35:1,': [1554], '(16-34),': [1555], '1-Mar-2022.': [1559, 1584], 'Meilhac': [1560], 'Cautela': [1562], 'J': [1563, 1623, 1664, 1807], 'Thuny': [1565], 'F': [1566, 1700, 1948], 'Cancer': [1568, 1748, 1925], 'Therapies': [1569], 'Toxicities,': [1572], 'Treatment': [1574, 1926, 2421], 'Options': [1575], 'Oncology,': [1577, 1599, 1895, 1933, 2251], '10.1007/s11864-022-00964-2,': [1578], '23:3,': [1579], '(333-347),': [1580], 'Sperandio': [1585], 'Schvartsman': [1588], 'G': [1589, 2161, 2171, 2301], 'Surgery': [1592, 1597, 2243], 'Oncology': [1595], '10.1007/978-3-030-97687-3_10,': [1600], '(347-363),': [1601], '.': [1602, 2131, 2390], 'Wang': [1603, 1615], 'Chen': [1605], 'Zhang': [1607, 1609, 2152], 'Jia': [1611], 'Shen': [1613, 1996], 'Z,': [1614], 'Zhao': [1617], 'Gong': [1619, 1622], 'Y': [1620], 'Aneurysm': [1625, 1859], 'Artery': [1627, 1928], 'Following': [1629], 'Use': [1631], 'Inhibitor:': [1637], 'Real‐World': [1639], 'Analysis': [1640, 1707], 'Spontaneous': [1643], 'Reporting': [1644, 1790], 'System,': [1645], 'Journal': [1646, 1679, 2075, 2106], 'American': [1649, 2366, 2488], 'Heart': [1650, 2367, 2431, 2489], 'Association,': [1651, 2368, 2490], '10:23,': [1652], '7-Dec-2021.': [1656], 'Willems': [1657], 'Mostard': [1659, 1661], 'Buijs': [1663], 'Twist': [1666], 'D': [1667, 1767, 2098], 'intramural': [1670], 'haematoma': [1671], 'nintedanib,': [1677], 'British': [1678], 'Pharmacology,': [1682, 1715], '10.1111/bcp.14861,': [1683], '87:11,': [1684], '(4467-4469),': [1685], '1-Nov-2021.': [1689], 'Allouchery': [1690], 'Tomowiak': [1692], 'Lombard': [1694], 'Pérault-Pochat': [1696], 'Salvo': [1699], 'Safety': [1702], 'Profile': [1703], 'Ibrutinib:': [1705], 'WHO': [1710], 'Pharmacovigilance': [1711, 1892], 'Database,': [1712], 'Frontiers': [1713], '10.3389/fphar.2021.769315,': [1716], '12': [1717], 'Tesolin': [1718], 'Alaref': [1720], 'Ibrahim': [1723], 'splenic': [1729], 'aneurysm': [1731, 1770], 'rupture': [1733], 'inhibitor': [1743, 1818], 'Reports,': [1749, 1837, 2469], '10.1002/cnr2.1567': [1750], 'Cheng': [1751], 'Nguyen': [1753], 'Nayernama': [1755], 'Jones': [1757], 'Brave': [1759], 'Agrawal': [1761], 'Amiri-Kordestani': [1763, 2336], 'L': [1764], 'Woronow': [1766], 'Arterial': [1769], 'inhibitors:': [1779], 'reported': [1784], 'FDA': [1787], 'System': [1791], 'literature,': [1796], 'Medicine,': [1798, 1988], '10.1177/1358863X211006470,': [1799], '26:5,': [1800], '(526-534),': [1801], '1-Oct-2021.': [1805, 1844], 'Ting': [1806], 'Lo': [1809], 'Z': [1810], 'targeted': [1819], 'therapy:': [1820], 'cause': [1823], 'acute': [1826], 'lesser': [1829], 'emergency': [1833], 'physician,': [1834], 'BMJ': [1835], '10.1136/bcr-2021-245653,': [1838], '14:10,': [1839], '(e245653),': [1840], 'Rysz': [1845], 'Gluba-Brzózka': [1847], 'Rokicki': [1849], 'Franczyk': [1852], 'B': [1853], 'Oxidative': [1855], 'Stress-Related': [1856], 'Susceptibility': [1857], 'Marfan’s': [1861], 'Syndrome,': [1862], 'Biomedicines,': [1863], '10.3390/biomedicines9091171,': [1864], '9:9,': [1865], '(1171)': [1866], 'Goldman': [1867], 'Bomze': [1869], 'Dankner': [1871], 'Fourey': [1873], 'Boursi': [1875], 'Arad': [1877], 'Maor': [1880], 'E': [1881], 'Cardiovascular': [1883, 2124, 2383], 'Toxicities': [1884], 'Antiangiogenic': [1886, 1921], 'Tyrosine': [1887, 1953], 'Kinase': [1888], 'Inhibitors:': [1889], 'Retrospective,': [1891], 'Study,': [1893], 'Targeted': [1894], '10.1007/s11523-021-00817-2,': [1896], '16:4,': [1897], '(471-483),': [1898], '1-Jul-2021.': [1902], 'Guyon': [1903], 'Gouverneur': [1905], 'Maumus-Robert': [1907], 'Bérard': [1909], 'Pariente': [1911], 'Bikfalvi': [1913], 'Noize': [1916], 'P': [1917, 2121, 2380], 'Association': [1919], 'Drugs': [1922], 'Used': [1923], 'Dissections': [1929, 2013], 'or': [1930], 'Aneurysms,': [1931], 'JAMA': [1932, 2250], '10.1001/jamaoncol.2021.0210,': [1934], '7:5,': [1935], '(775),': [1936], '1-May-2021.': [1940], 'Dörks': [1941], 'Jobski': [1943], 'Herget‐Rosenthal': [1945], 'Hoffmann': [1947], 'Douros': [1950], 'targeting': [1956], 'dissection—A': [1966], 'pharmacovigilance': [1967], 'Pharmacology': [1969], 'Research': [1970], '&': [1971], 'Perspectives,': [1972], '10.1002/prp2.707,': [1973], '9:1,': [1974], '1-Feb-2021.': [1978], 'Campia': [1979, 2332], 'U': [1980], '(2020)': [1981, 2009, 2122], 'effects': [1983], 'treatments,': [1986], '10.1177/1358863X20914978,': [1989], '25:3,': [1990], '(226-234),': [1991], '1-Jun-2020.': [1995], 'LeMaire': [1998], 'Webb': [2000], 'Cassis': [2002], 'Daugherty': [2004], 'Lu': [2007], 'H': [2008], 'Aneurysms': [2011], 'Series:': [2014], 'Part': [2015], 'II,': [2016], 'Arteriosclerosis,': [2017], 'Thrombosis,': [2018], 'Biology,': [2021], '40:4,': [2022], '(e78-e86),': [2023], '1-Apr-2020.': [2027, 2084], 'Nawa': [2028], 'Katayama': [2030], 'Kiyota': [2032], 'Imai': [2034], 'Abe': [2036], 'Hasegawa': [2038], 'Takada': [2040, 2391], 'Fukutake': [2042], 'Ikezawa': [2044], 'Sakakibara': [2046], 'Fujita': [2048, 2408], 'Ohkawa': [2051], 'K': [2052, 2264], '(2019)': [2053, 2099, 2165, 2230, 2268, 2302, 2355, 2381], 'thrombus': [2057], 'superior': [2060], 'mesenteric': [2061], 'sequential': [2065], 'Gastroenterology,': [2077], '10.1007/s12328-019-01021-6,': [2078], '13:2,': [2079], '(247-251),': [2080], 'Zenoni': [2085], 'Beretta': [2087], 'Martinelli': [2089], 'V,': [2090, 2204], 'Iaculli': [2091], 'Benzoni': [2093], 'Fratelli': [2094], 'Bonzi': [2097], 'ramucirumab': [2103], 'infusion,': [2104], 'European': [2105], 'Pharmacy,': [2109], '10.1136/ejhpharm-2019-001879,': [2110], '27:2,': [2111], '(117-120),': [2112], '1-Mar-2020.': [2116], 'Hussain': [2117, 2376], 'Collier': [2120, 2379], 'Chemotherapy-Related': [2123, 2382], 'Complications': [2125, 2384], 'Oncologic': [2126, 2385], 'Critical': [2127, 2386], 'Care,': [2128, 2387], '10.1007/978-3-319-74588-6_70,': [2129], '(815-836),': [2130], 'Schwaerzer': [2132], 'Kalyanaraman': [2134], 'Casteel': [2136], 'Dalton': [2138], 'Gu': [2140], 'Zhuang': [2144], 'Wahwah': [2146], 'Schilling': [2148], 'Patel': [2150], 'Q,': [2153], 'Makino': [2154], 'Peterson': [2158], 'Boss': [2160], 'Pilz': [2163], 'pathology': [2167], 'protein': [2169], 'activation': [2172], 'prevented': [2174], 'antioxidant': [2177], 'vitamin': [2178], 'B12': [2179], 'analog,': [2180], 'Nature': [2181], 'Communications,': [2182], '10.1038/s41467-019-11389-1,': [2183], '10:1,': [2184], '1-Dec-2019.': [2188], 'Fernández-Martos': [2189], 'Pericay': [2191], 'Losa': [2193], 'García-Carbonero': [2195], 'Layos': [2197], 'Rodríguez-Salas': [2199], 'Martin-Richard': [2201], 'Alonso-Orduña': [2203], 'Vera': [2205], 'Gallego': [2207], 'Capdevila': [2209], 'Salud': [2211], 'Nogué': [2213], 'Maurel': [2215], 'Guash': [2217], 'I,': [2218, 2224], 'Montagut': [2219], 'Lopez': [2221], 'Macias': [2223], 'Jain': [2225], 'Garcia-Albeniz': [2228], 'X': [2229], 'Effect': [2231], 'Aflibercept': [2233], 'Plus': [2234], 'Modified': [2235], 'FOLFOX6': [2236], 'Induction': [2237], 'Chemotherapy': [2238], 'Before': [2239], 'Standard': [2240], 'Chemoradiotherapy': [2241], 'High-Risk': [2247], 'Rectal': [2248], 'Adenocarcinoma,': [2249], '10.1001/jamaoncol.2019.2294,': [2252], '5:11,': [2253], '(1566),': [2254], '1-Nov-2019.': [2258], 'Takahashi': [2261], 'Tani': [2263], 'Granulocyte': [2269], 'colony-stimulating': [2270], 'factor-associated': [2271], 'aortitis': [2272], 'Cytokine,': [2281], '10.1016/j.cyto.2019.02.013,': [2282], '119,': [2283], '(47-51),': [2284], '1-Jul-2019.': [2288], 'Pucci': [2289], 'Milan': [2291], 'Paini': [2293], 'Salvetti': [2295], 'Cerasari': [2297], 'Vaudo': [2300], 'elevation': [2306], 'biological': [2309], 'therapies': [2310], 'cancer:': [2312], 'focus': [2314], 'VEGF': [2316], 'signaling': [2317], 'Expert': [2320], 'Opinion': [2321], 'Biological': [2323], 'Therapy,': [2324], '10.1080/14712598.2019.1594770,': [2325], '19:5,': [2326], '(433-442),': [2327], '4-May-2019.': [2331], 'U,': [2333], 'Moslehi': [2334], 'Barac': [2338], 'Beckman': [2340], 'Chism': [2342], 'Cohen': [2344], 'Groarke': [2346], 'Herrmann': [2348], 'Reilly': [2350], 'Weintraub': [2353], 'Cardio-Oncology:': [2356], 'Metabolic': [2359], 'Perspectives:': [2360], 'Scientific': [2362], 'Statement': [2363], 'Circulation,': [2369], '139:13,': [2370], '(e579-e602),': [2371], '26-Mar-2019.': [2375], '10.1007/978-3-319-74698-2_70-1,': [2388], '(1-23),': [2389], 'Yasui': [2393], 'Oka': [2395], 'Shioyama': [2397], 'Kuroda': [2399], 'Nakai': [2401], 'Nishimura': [2403], 'Mukai': [2405], '(2018)': [2410, 2455], 'Cardiac': [2414], 'Dysfunction': [2415], 'Emerged': [2416], 'Coincidentally': [2417], 'During': [2418], 'Long-Term': [2420], 'Angiogenesis': [2423], 'Metastatic': [2426], 'Renal': [2427], 'Cell': [2428], 'Carcinoma,': [2429], 'International': [2430], 'Journal,': [2432], '10.1536/ihj.17-461,': [2433], '59:5,': [2434], '(1174-1179),': [2435], '1-Sep-2018.': [2439], 'Tsuchiya': [2440], 'Ogawa': [2442], 'Watanabe': [2444], 'Kimura': [2446], 'Hayashi': [2448], 'Suda': [2450], 'T': [2451], 'Terai': [2453], 'Successful': [2456], 'sorafenib': [2462], '10.1002/ccr3.1674,': [2470], '6:8,': [2471], '(1643-1644),': [2472], '1-Aug-2018.': [2476], 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