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[56, 275], 'examined': [57], 'expression': [59], 'RELN,': [61, 228, 256, 297], 'GAD1,': [62, 227, 257], 'GAD2,': [63], 'several': [65, 259], 'other': [66, 260], 'this': [70], 'disorder': [71], 'frontal': [74], 'cortices': [75], '(FC)': [76], 'CON': [80, 140], 'subjects.': [81], 'also': [83, 214], 'focused': [84], 'on': [85], 'role': [87], 'epigenetic': [89], 'processes': [90], 'play': [91], 'regulation': [94], 'these': [96, 248, 287, 314], 'genes': [97, 114, 130, 174, 261], 'brain.': [100], 'Our': [101, 252], 'goal': [102], 'is': [103], 'better': [105], 'understand': [106], 'molecular': [108], 'basis': [109], 'for': [110], 'down‐regulation': [112], 'expressed': [115, 263], 'GABAergic': [117, 129, 265], 'neurons': [118], 'brains.': [121], 'measured': [123], 'mRNA': [124], 'levels': [125], 'selected': [128, 329], 'using': [131], 'qRT‐PCR': [132], 'RNA': [134], 'isolated': [135], 'from': [136, 335], 'groups.': [141], 'determined': [143], 'extent': [145], 'DNMT1': [151, 219, 278, 320], 'repressor': [152], 'proteins': [153], 'by': [154, 177], 'chromatin': [155], 'immunoprecipitation': [156, 180], '(ChIP)': [157], 'assays.': [158], 'The': [159, 289], 'amount': [160], '5‐methylcytosine': [162], '(5mC)': [163], '5‐hydroxymethylcytosine': [165], '(5hmC)': [166], 'present': [167, 312], 'promoters': [170, 240, 285], 'target': [173], 'was': [175], 'quantified': [176], 'methyl': [178], 'DNA': [179, 250], '(MeDIP)': [181], 'hydroxyl': [183], 'MeDIP': [184], '(hMeDIP).': [185], 'detected': [187, 215], 'significant': [188, 199], 'reductions': [189], 'associated': [193], 'with': [194, 302, 322, 338], 'RELN': [195], 'GAD1': [197, 298], 'encoding': [203], 'Ten‐eleven': [205], 'Translocation': [206], '(TET)': [207], 'enzymes': [208], '1,': [209], '2,': [210], '3.': [212], 'increased': [216, 277, 292], 'promoter': [224], 'regions': [225, 347], 'GAD2.': [230], 'Interestingly,': [231], 'there': [232], 'were': [233], 'decreased': [234], '5mC': [237, 306], 'at': [238, 282], 'little': [242], 'change': [243], '5hmC': [245, 311], 'content': [246], 'same': [249], 'fragments.': [251], 'data': [253, 333], 'demonstrate': [254], 'selectively': [262], 'neurons,': [266], 'down‐regulated': [268], 'post‐mortem': [270], 'FC.': [272], 'addition,': [274], 'observed': [276], 'genes.': [288], 'finding': [290], 'GAD2': [300], 'promoters,': [301], 'unchanged': [308], 'regions,': [315], 'suggests': [316], 'possibility': [318], 'interacts': [321], 'alters': [324], 'properties': [327], 'Comparisons': [331], 'between': [332, 345], 'obtained': [334], 'FC': [337], 'CB': [339], 'studies': [340], 'showed': [341], 'some': [342], 'common': [343], 'themes': [344], 'brain': [346], 'which': [348], 'discussed.': [350]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2589091265', 'counts_by_year': [{'year': 2024, 'cited_by_count': 13}, {'year': 2023, 'cited_by_count': 8}, {'year': 2022, 'cited_by_count': 10}, {'year': 2021, 'cited_by_count': 12}, {'year': 2020, 'cited_by_count': 2}, {'year': 2019, 'cited_by_count': 7}, {'year': 2018, 'cited_by_count': 6}, {'year': 2017, 'cited_by_count': 3}], 'updated_date': '2025-01-10T07:33:05.628622', 'created_date': '2017-02-24'}